| Type |
Details |
Score |
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Itgb1/Itgb1 Tg(PLAT-cre)116Sdu/? |
| Background: |
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Itgb1/Itgb1<+> Tg(PLAT-cre)116Sdu/? |
| Background: |
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Itgb1/Itgb1<+> Sox10/Sox10<+> Tg(PLAT-cre)116Sdu/? |
| Background: |
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Iha M |
| Year: |
2012 |
| Journal: |
Reproduction |
| Title: |
Effect of ectopic expression of homeoprotein EGAM1C on the cell morphology, growth, and differentiation in a mouse embryonic stem cell line, MG1.19 cells. |
| Volume: |
143 |
| Issue: |
4 |
| Pages: |
477-89 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Szklarczyk K |
| Year: |
2012 |
| Journal: |
Genes Brain Behav |
| Title: |
Genotype-dependent consequences of traumatic stress in four inbred mouse strains. |
| Volume: |
11 |
| Issue: |
8 |
| Pages: |
977-85 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Homologous_superfamily |
| Description: |
This entry represents a domain superfamily found in a variety of membrane or lipid associated proteins. It is known as the PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology) domain, is found in a variety of membrane or lipid associated proteins. Structurally, this domain forms a β-sandwich composed of two sheets of four strands each [, , ]. The most highly conserved regions coincide with the β-strands, with most of the highly conserved residues being buried within the protein. An exception to this is a surface lysine or arginine that occurs on the surface of the fifth β-strand of the eukaryotic domains. In pancreatic lipase, the lysine in this position forms a salt bridge with the procolipase protein. The conservation of a charged surface residue may indicate the location of a conserved ligand-binding site. It is thought that this domain may mediate membrane attachment via other protein binding partners. |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
This entry represents a domain found in a variety of membrane or lipid associated proteins. It is known as the PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology) domain, is found in a variety of membrane or lipid associated proteins. Structurally, this domain forms a β-sandwich composed of two sheets of four strands each [, , ]. The most highly conserved regions coincide with the β-strands, with most of the highly conserved residues being buried within the protein. An exception to this is a surface lysine or arginine that occurs on the surface of the fifth β-strand of the eukaryotic domains. In pancreatic lipase, the lysine in this position forms a salt bridge with the procolipase protein. The conservation of a charged surface residue may indicate the location of a conserved ligand-binding site. It is thought that this domain may mediate membrane attachment via other protein binding partners. |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2068
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2080
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
996
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2216
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tomchick DR |
| Year: |
2001 |
| Journal: |
Biochemistry |
| Title: |
Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1. |
| Volume: |
40 |
| Issue: |
25 |
| Pages: |
7509-17 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Delrieu I |
| Year: |
2002 |
| Journal: |
Mol Biochem Parasitol |
| Title: |
PSLAP, a protein with multiple adhesive motifs, is expressed in Plasmodium falciparum gametocytes. |
| Volume: |
121 |
| Issue: |
1 |
| Pages: |
11-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Maphis NM |
| Year: |
2017 |
| Journal: |
Front Mol Neurosci |
| Title: |
Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology. |
| Volume: |
10 |
|
| Pages: |
69 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
234
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Matsuwaki T |
| Year: |
2017 |
| Journal: |
Brain Behav Immun |
| Title: |
Involvement of interleukin-1 type 1 receptors in lipopolysaccharide-induced sickness responses. |
| Volume: |
66 |
|
| Pages: |
165-176 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Broders-Bondon F |
| Year: |
2012 |
| Journal: |
Dev Biol |
| Title: |
N-cadherin and β1-integrins cooperate during the development of the enteric nervous system. |
| Volume: |
364 |
| Issue: |
2 |
| Pages: |
178-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Broders-Bondon F |
| Year: |
2016 |
| Journal: |
Dev Biol |
| Title: |
Control of the collective migration of enteric neural crest cells by the Complement anaphylatoxin C3a and N-cadherin. |
| Volume: |
414 |
| Issue: |
1 |
| Pages: |
85-99 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Breau MA |
| Year: |
2008 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A nonneural epithelial domain of embryonic cranial neural folds gives rise to ectomesenchyme. |
| Volume: |
105 |
| Issue: |
22 |
| Pages: |
7750-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Watanabe Y |
| Year: |
2013 |
| Journal: |
Dev Biol |
| Title: |
Sox10 and Itgb1 interaction in enteric neural crest cell migration. |
| Volume: |
379 |
| Issue: |
1 |
| Pages: |
92-106 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Breau MA |
| Year: |
2009 |
| Journal: |
Development |
| Title: |
Beta1 integrins are required for the invasion of the caecum and proximal hindgut by enteric neural crest cells. |
| Volume: |
136 |
| Issue: |
16 |
| Pages: |
2791-801 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chevalier NR |
| Year: |
2021 |
| Journal: |
Commun Biol |
| Title: |
A neural crest cell isotropic-to-nematic phase transition in the developing mammalian gut. |
| Volume: |
4 |
| Issue: |
1 |
| Pages: |
770 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
John A |
| Year: |
2012 |
| Journal: |
Development |
| Title: |
Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development. |
| Volume: |
139 |
| Issue: |
10 |
| Pages: |
1831-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tamura Y |
| Year: |
2011 |
| Journal: |
Arterioscler Thromb Vasc Biol |
| Title: |
Neural crest-derived stem cells migrate and differentiate into cardiomyocytes after myocardial infarction. |
| Volume: |
31 |
| Issue: |
3 |
| Pages: |
582-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gacem N |
| Year: |
2020 |
| Journal: |
Nat Commun |
| Title: |
ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
198 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Coulpier F |
| Year: |
2009 |
| Journal: |
Glia |
| Title: |
Novel features of boundary cap cells revealed by the analysis of newly identified molecular markers. |
| Volume: |
57 |
| Issue: |
13 |
| Pages: |
1450-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huettl RE |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
Npn-1 contributes to axon-axon interactions that differentially control sensory and motor innervation of the limb. |
| Volume: |
9 |
| Issue: |
2 |
| Pages: |
e1001020 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chevalier NR |
| Year: |
2021 |
| Journal: |
Front Cell Dev Biol |
| Title: |
How Smooth Muscle Contractions Shape the Developing Enteric Nervous System. |
| Volume: |
9 |
|
| Pages: |
678975 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yoshida Y |
| Year: |
2006 |
| Journal: |
Neuron |
| Title: |
PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord. |
| Volume: |
52 |
| Issue: |
5 |
| Pages: |
775-88 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Cdh2/Cdh2<+> Itgb1/Itgb1<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(PLAT-cre)116Sdu/? |
| Background: |
involves: 129 * C57BL/6 * DBA/2 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Cdh2/Cdh2 Itgb1/Itgb1<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(PLAT-cre)116Sdu/? |
| Background: |
involves: 129 * C57BL/6 * DBA/2 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Cdh2/Cdh2 Itgb1/Itgb1 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(PLAT-cre)116Sdu/? |
| Background: |
involves: 129 * C57BL/6 * DBA/2 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Cdh2/Cdh2<+> Itgb1/Itgb1 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(PLAT-cre)116Sdu/? |
| Background: |
involves: 129 * C57BL/6 * DBA/2 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Itgb1/Itgb1 Sox10/Sox10<+> Tg(PLAT-cre)116Sdu/? |
| Background: |
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Womack JE |
| Year: |
1989 |
| Journal: |
Cytogenet Cell Genet |
| Title: |
Syntenic mapping of 37 loci in cattle. Chromosomal conservation with mouse and man. |
| Volume: |
51 |
|
| Pages: |
1109 (Abstr.) |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kubota Y |
| Year: |
2011 |
| Journal: |
J Exp Med |
| Title: |
Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero. |
| Volume: |
208 |
| Issue: |
5 |
| Pages: |
949-60 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lagerström MC |
| Year: |
2010 |
| Journal: |
Neuron |
| Title: |
VGLUT2-dependent sensory neurons in the TRPV1 population regulate pain and itch. |
| Volume: |
68 |
| Issue: |
3 |
| Pages: |
529-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ohayon D |
| Year: |
2015 |
| Journal: |
Dev Cell |
| Title: |
Zeb family members and boundary cap cells underlie developmental plasticity of sensory nociceptive neurons. |
| Volume: |
33 |
| Issue: |
3 |
| Pages: |
343-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kalamarides M |
| Year: |
2011 |
| Journal: |
Oncogene |
| Title: |
Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes. |
| Volume: |
30 |
| Issue: |
20 |
| Pages: |
2333-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Van Ho AT |
| Year: |
2011 |
| Journal: |
Dev Cell |
| Title: |
Neural crest cell lineage restricts skeletal muscle progenitor cell differentiation through Neuregulin1-ErbB3 signaling. |
| Volume: |
21 |
| Issue: |
2 |
| Pages: |
273-87 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huettl RE |
| Year: |
2011 |
| Journal: |
Dev Biol |
| Title: |
Cranial nerve fasciculation and Schwann cell migration are impaired after loss of Npn-1. |
| Volume: |
359 |
| Issue: |
2 |
| Pages: |
230-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vahedi-Hunter TA |
| Year: |
2018 |
| Journal: |
Sci Rep |
| Title: |
Cas Adaptor Proteins Coordinate Sensory Axon Fasciculation. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
5996 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Coulpier F |
| Year: |
2010 |
| Journal: |
J Neurosci |
| Title: |
CNS/PNS boundary transgression by central glia in the absence of Schwann cells or Krox20/Egr2 function. |
| Volume: |
30 |
| Issue: |
17 |
| Pages: |
5958-67 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1371
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2070
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1231
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
de Nooij JC |
| Year: |
2013 |
| Journal: |
Neuron |
| Title: |
Etv1 inactivation reveals proprioceptor subclasses that reflect the level of NT3 expression in muscle targets. |
| Volume: |
77 |
| Issue: |
6 |
| Pages: |
1055-68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Coppola E |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Epibranchial ganglia orchestrate the development of the cranial neurogenic crest. |
| Volume: |
107 |
| Issue: |
5 |
| Pages: |
2066-71 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
473
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
474
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
500
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
510
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
482
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
465
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
474
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
474
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
474
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
474
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
459
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1479
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
474
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
474
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
474
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
474
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
500
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
474
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
474
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
474
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
500
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
474
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
474
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
474
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
474
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
464
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
500
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
425
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang P |
| Year: |
2024 |
| Journal: |
Nat Commun |
| Title: |
LOXHD1 is indispensable for maintaining TMC1 auditory mechanosensitive channels at the site of force transmission. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
7865 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1274
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1287
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2201
 |
| Fragment?: |
false |
|
•
•
•
•
•
|