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Search results 701 to 800 out of 3238 for Psen1

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Type Details Score
Publication
18021291 | J:141555
First Author: Lopez JR
Year: 2008
Journal: J Neurochem
Title: Increased intraneuronal resting [Ca2+] in adult Alzheimer's disease mice.
Volume: 105
Issue: 1
Pages: 262-71
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21829458 | J:284814
First Author: Bianchi FT
Year: 2011
Journal: PLoS One
Title: The collagen chaperone HSP47 is a new interactor of APP that affects the levels of extracellular beta-amyloid peptides.
Volume: 6
Issue: 7
Pages: e22370
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Publication
25447943 | J:231418
 
First Author: Hohsfield LA
Year: 2014
Journal: Mol Cell Neurosci
Title: Vascular pathology of 20-month-old hypercholesterolemia mice in comparison to triple-transgenic and APPSwDI Alzheimer's disease mouse models.
Volume: 63
Pages: 83-95
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Publication
22367970 | J:183771
First Author: Manczak M
Year: 2012
Journal: Hum Mol Genet
Title: Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage.
Volume: 21
Issue: 11
Pages: 2538-47
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Publication
27470171 | J:236530
First Author: Höfling C
Year: 2016
Journal: Aging Cell
Title: Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein-specific antibodies.
Volume: 15
Issue: 5
Pages: 953-63
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Publication
25947203 | J:351760
First Author: Plagg B
Year: 2015
Journal: Biogerontology
Title: Platelet dysfunction in hypercholesterolemia mice, two Alzheimer's disease mouse models and in human patients with Alzheimer's disease.
Volume: 16
Issue: 4
Pages: 543-58
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Publication
32920368 | J:348446
 
First Author: Danielyan L
Year: 2020
Journal: EBioMedicine
Title: Cell motility and migration as determinants of stem cell efficacy.
Volume: 60
Pages: 102989
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Publication
26159193 | J:264838
First Author: Plagg B
Year: 2015
Journal: Curr Alzheimer Res
Title: Increased Acetylation of Histone H4 at Lysine 12 (H4K12) in Monocytes of Transgenic Alzheimer's Mice and in Human Patients.
Volume: 12
Issue: 8
Pages: 752-60
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Publication
36451854 | J:348479
First Author: Yang H
Year: 2022
Journal: Theranostics
Title: Adoptive therapy with amyloid-β specific regulatory T cells alleviates Alzheimer's disease.
Volume: 12
Issue: 18
Pages: 7668-7680
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Publication
33192524 | J:313486
 
First Author: Iyaswamy A
Year: 2020
Journal: Front Pharmacol
Title: Yuan-Hu Zhi Tong Prescription Mitigates Tau Pathology and Alleviates Memory Deficiency in the Preclinical Models of Alzheimer's Disease.
Volume: 11
Pages: 584770
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Publication
18800967 | J:141307
First Author: Ribe EM
Year: 2008
Journal: Biochem J
Title: Mechanisms of neuronal death in disease: defining the models and the players.
Volume: 415
Issue: 2
Pages: 165-82
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Publication
19664757 | J:281363
First Author: España J
Year: 2010
Journal: Biol Psychiatry
Title: Intraneuronal beta-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice.
Volume: 67
Issue: 6
Pages: 513-21
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Publication
15951428 | J:99874
First Author: Mastrangelo P
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Dissociated phenotypes in presenilin transgenic mice define functionally distinct gamma-secretases.
Volume: 102
Issue: 25
Pages: 8972-7
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24828645 | J:211264
First Author: Shilling D
Year: 2014
Journal: J Neurosci
Title: Suppression of InsP3 receptor-mediated Ca2+ signaling alleviates mutant presenilin-linked familial Alzheimer's disease pathogenesis.
Volume: 34
Issue: 20
Pages: 6910-23
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Publication
21741124 | J:188201
First Author: Minami SS
Year: 2012
Journal: Neurobiol Aging
Title: Fyn knock-down increases Aβ, decreases phospho-tau, and worsens spatial learning in 3×Tg-AD mice.
Volume: 33
Issue: 4
Pages: 825.e15-24
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Publication
31814000 | J:285091
First Author: Kim J
Year: 2020
Journal: Hum Mol Genet
Title: Ca2+-permeable TRPV1 pain receptor knockout rescues memory deficits and reduces amyloid-β and tau in a mouse model of Alzheimer's disease.
Volume: 29
Issue: 2
Pages: 228-237
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Publication
28641077 | J:244252
First Author: Qin X
Year: 2017
Journal: Am J Pathol
Title: Inhibition of Early Growth Response 1 in the Hippocampus Alleviates Neuropathology and Improves Cognition in an Alzheimer Model with Plaques and Tangles.
Volume: 187
Issue: 8
Pages: 1828-1847
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21531375 | J:173178
First Author: Sy M
Year: 2011
Journal: Am J Pathol
Title: Inflammation induced by infection potentiates tau pathological features in transgenic mice.
Volume: 178
Issue: 6
Pages: 2811-22
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37253603 | J:340905
First Author: Landry O
Year: 2023
Journal: J Neurosci
Title: Postsynaptic Protein Shank3a Deficiency Synergizes with Alzheimer's Disease Neuropathology to Impair Cognitive Performance in the 3xTg-AD Murine Model.
Volume: 43
Issue: 26
Pages: 4941-4954
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24411482 | J:213887
First Author: Orr ME
Year: 2014
Journal: Neurobiol Aging
Title: Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology.
Volume: 35
Issue: 6
Pages: 1233-42
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Publication
27509875 | J:241263
 
First Author: Daniels MJ
Year: 2016
Journal: Nat Commun
Title: Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models.
Volume: 7
Pages: 12504
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Publication
27586053 | J:238228
 
First Author: Griffith CM
Year: 2016
Journal: Neuroscience
Title: Aberrant expression of the pore-forming KATP channel subunit Kir6.2 in hippocampal reactive astrocytes in the 3xTg-AD mouse model and human Alzheimer's disease.
Volume: 336
Pages: 81-101
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Publication
36331820 | J:351377
First Author: Colussi C
Year: 2023
Journal: Neuropathol Appl Neurobiol
Title: Cytoplasmic HDAC4 recovers synaptic function in the 3×Tg mouse model of Alzheimer's disease.
Volume: 49
Issue: 1
Pages: e12861
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Publication
37061718 | J:349106
First Author: Wander CM
Year: 2023
Journal: J Transl Med
Title: Compensatory remodeling of a septo-hippocampal GABAergic network in the triple transgenic Alzheimer's mouse model.
Volume: 21
Issue: 1
Pages: 258
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Publication
20875398 | J:166163
First Author: Chakravarthy B
Year: 2010
Journal: Biochem Biophys Res Commun
Title: The p75 neurotrophin receptor is localized to primary cilia in adult murine hippocampal dentate gyrus granule cells.
Volume: 401
Issue: 3
Pages: 458-62
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Publication
27709751 | J:239335
     
First Author: Wyssenbach A
Year: 2016
Journal: Aging Cell
Title: Amyloid β-induced astrogliosis is mediated by β1-integrin via NADPH oxidase 2 in Alzheimer's disease.
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Publication
25309427 | J:288953
 
First Author: Castro-Alvarez JF
Year: 2014
Journal: Front Aging Neurosci
Title: Long- and short-term CDK5 knockdown prevents spatial memory dysfunction and tau pathology of triple transgenic Alzheimer's mice.
Volume: 6
Pages: 243
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Publication
29632073 | J:264136
First Author: Mondragón-Rodríguez S
Year: 2018
Journal: J Biol Chem
Title: Phosphorylation of Tau protein correlates with changes in hippocampal theta oscillations and reduces hippocampal excitability in Alzheimer's model.
Volume: 293
Issue: 22
Pages: 8462-8472
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Publication
19497998 | J:150061
First Author: Takata K
Year: 2009
Journal: Am J Pathol
Title: Involvement of WAVE accumulation in Abeta/APP pathology-dependent tangle modification in Alzheimer's disease.
Volume: 175
Issue: 1
Pages: 17-24
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Publication
19633196 | J:152002
First Author: Blurton-Jones M
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease.
Volume: 106
Issue: 32
Pages: 13594-9
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Publication
25552414 | J:223234
First Author: Sykora P
Year: 2015
Journal: Nucleic Acids Res
Title: DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes.
Volume: 43
Issue: 2
Pages: 943-59
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Publication
18974297 | J:143926
First Author: Janelsins MC
Year: 2008
Journal: Am J Pathol
Title: Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice.
Volume: 173
Issue: 6
Pages: 1768-82
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Publication
39179121 | J:353954
 
First Author: Marmolejo-Garza A
Year: 2024
Journal: Neurobiol Dis
Title: Nicotinamide riboside modulates the reactive species interactome, bioenergetic status and proteomic landscape in a brain-region-specific manner.
Volume: 200
Pages: 106645
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Publication
29643768 | J:269539
 
First Author: Ross SP
Year: 2018
Journal: Front Cell Neurosci
Title: miRNA-431 Prevents Amyloid-β-Induced Synapse Loss in Neuronal Cell Culture Model of Alzheimer's Disease by Silencing Kremen1.
Volume: 12
Pages: 87
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Publication
31334659 | J:294124
First Author: Adler P
Year: 2019
Journal: J Proteome Res
Title: Therapeutic Targeting of Casein Kinase 1δ/ε in an Alzheimer's Disease Mouse Model.
Volume: 18
Issue: 9
Pages: 3383-3393
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Publication
25711385 | J:286059
First Author: Castro-Alvarez JF
Year: 2015
Journal: J Neurosci Res
Title: Cyclin-Dependent kinase 5 targeting prevents β-Amyloid aggregation involving glycogen synthase kinase 3β and phosphatases.
Volume: 93
Issue: 8
Pages: 1258-66
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Publication
19772895 | J:155135
First Author: Robertson RT
Year: 2009
Journal: Neuroscience
Title: Amyloid-beta expression in retrosplenial cortex of triple transgenic mice: relationship to cholinergic axonal afferents from medial septum.
Volume: 164
Issue: 3
Pages: 1334-46
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Publication
37499037 | J:339456
First Author: Zhang ZY
Year: 2023
Journal: Science
Title: TRIM11 protects against tauopathies and is down-regulated in Alzheimer's disease.
Volume: 381
Issue: 6656
Pages: eadd6696
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Publication
34469732 | J:311306
First Author: Brigas HC
Year: 2021
Journal: Cell Rep
Title: IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer's disease.
Volume: 36
Issue: 9
Pages: 109574
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Publication
34437570 | J:311297
First Author: Lee SH
Year: 2021
Journal: PLoS One
Title: Three month inhalation exposure to low-level PM2.5 induced brain toxicity in an Alzheimer's disease mouse model.
Volume: 16
Issue: 8
Pages: e0254587
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Publication
33227902 | J:305094
 
First Author: Espino de la Fuente-Muñoz C
Year: 2020
Journal: Int J Mol Sci
Title: Age-Dependent Decline in Synaptic Mitochondrial Function Is Exacerbated in Vulnerable Brain Regions of Female 3xTg-AD Mice.
Volume: 21
Issue: 22
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Publication
26830653 | J:348414
 
First Author: Cho SM
Year: 2016
Journal: Sci Rep
Title: Age-dependent inverse correlations in CSF and plasma amyloid-β(1-42) concentrations prior to amyloid plaque deposition in the brain of 3xTg-AD mice.
Volume: 6
Pages: 20185
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Publication
30734228 | J:358330
First Author: Li L
Year: 2019
Journal: Mol Neurobiol
Title: Pathological Alterations of Tau in Alzheimer's Disease and 3xTg-AD Mouse Brains.
Volume: 56
Issue: 9
Pages: 6168-6183
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Publication
23520537 | J:200185
First Author: Badiola N
Year: 2013
Journal: PLoS One
Title: The proton-pump inhibitor lansoprazole enhances amyloid beta production.
Volume: 8
Issue: 3
Pages: e58837
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Publication
24176788 | J:207203
 
First Author: Baglietto-Vargas D
Year: 2014
Journal: Neurobiol Dis
Title: Endogenous murine tau promotes neurofibrillary tangles in 3xTg-AD mice without affecting cognition.
Volume: 62
Pages: 407-15
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Publication
32578216 | J:304693
First Author: Li W
Year: 2020
Journal: J Neurochem
Title: Intermittent fasting promotes adult hippocampal neuronal differentiation by activating GSK-3β in 3xTg-AD mice.
Volume: 155
Issue: 6
Pages: 697-713
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Publication
26582141 | J:290046
 
First Author: Hou X
Year: 2015
Journal: Front Aging Neurosci
Title: Differential contributions of ApoE4 and female sex to BACE1 activity and expression mediate Aβ deposition and learning and memory in mouse models of Alzheimer's disease.
Volume: 7
Pages: 207
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Publication
16282321 | J:107286
First Author: Oddo S
Year: 2006
Journal: J Biol Chem
Title: Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology.
Volume: 281
Issue: 3
Pages: 1599-604
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Publication
31062249 | J:348502
First Author: Ting LL
Year: 2019
Journal: Mol Neurobiol
Title: Expression of AHI1 Rescues Amyloidogenic Pathology in Alzheimer's Disease Model Cells.
Volume: 56
Issue: 11
Pages: 7572-7582
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Publication
32528242 | J:311334
 
First Author: Dionisio-Santos DA
Year: 2020
Journal: Front Neurosci
Title: Evaluating the Effect of Interleukin-4 in the 3xTg Mouse Model of Alzheimer's Disease.
Volume: 14
Pages: 441
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Publication
23632329 | J:348504
First Author: Noh MY
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Newly developed glycogen synthase kinase-3 (GSK-3) inhibitors protect neuronal cells death in amyloid-beta induced cell model and in a transgenic mouse model of Alzheimer's disease.
Volume: 435
Issue: 2
Pages: 274-81
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Publication
30484658 | J:348506
First Author: Zhou X
Year: 2019
Journal: J Proteome Res
Title: Hippocampal Proteomic Alteration in Triple Transgenic Mouse Model of Alzheimer's Disease and Implication of PINK 1 Regulation in Donepezil Treatment.
Volume: 18
Issue: 4
Pages: 1542-1552
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Publication
25344396 | J:355781
First Author: Gstir R
Year: 2014
Journal: RNA
Title: Generation of a neuro-specific microarray reveals novel differentially expressed noncoding RNAs in mouse models for neurodegenerative diseases.
Volume: 20
Issue: 12
Pages: 1929-43
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32084533 | J:311344
 
First Author: Singulani MP
Year: 2020
Journal: Exp Gerontol
Title: Impairment of PGC-1α-mediated mitochondrial biogenesis precedes mitochondrial dysfunction and Alzheimer's pathology in the 3xTg mouse model of Alzheimer's disease.
Volume: 133
Pages: 110882
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20576032 | J:171787
First Author: Noristani HN
Year: 2010
Journal: Eur J Neurosci
Title: Serotonin fibre sprouting and increase in serotonin transporter immunoreactivity in the CA1 area of hippocampus in a triple transgenic mouse model of Alzheimer's disease.
Volume: 32
Issue: 1
Pages: 71-9
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Publication
32585593 | J:311347
First Author: Wander CM
Year: 2020
Journal: iScience
Title: The Accumulation of Tau-Immunoreactive Hippocampal Granules and Corpora Amylacea Implicates Reactive Glia in Tau Pathogenesis during Aging.
Volume: 23
Issue: 7
Pages: 101255
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Publication
27686631 | J:238755
First Author: Misiak M
Year: 2017
Journal: Aging Cell
Title: DNA polymerase β decrement triggers death of olfactory bulb cells and impairs olfaction in a mouse model of Alzheimer's disease.
Volume: 16
Issue: 1
Pages: 162-172
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Publication
33083725 | J:311348
First Author: Navarro JF
Year: 2020
Journal: iScience
Title: Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease.
Volume: 23
Issue: 10
Pages: 101556
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Publication
25457549 | J:219505
First Author: Lauretti E
Year: 2015
Journal: Neurobiol Aging
Title: Modulation of AD neuropathology and memory impairments by the isoprostane F2α is mediated by the thromboxane receptor.
Volume: 36
Issue: 2
Pages: 812-20
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Publication
29432159 | J:257524
First Author: Hou Y
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: NAD+ supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency.
Volume: 115
Issue: 8
Pages: E1876-E1885
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Publication
32768866 | J:299545
 
First Author: Russo-Savage L
Year: 2020
Journal: Neurobiol Aging
Title: Role of Kalirin and mouse strain in retention of spatial memory training in an Alzheimer's disease model mouse line.
Volume: 95
Pages: 69-80
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Publication
21784978 | J:176011
First Author: Müller M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Constitutive cAMP response element binding protein (CREB) activation by Alzheimer's disease presenilin-driven inositol trisphosphate receptor (InsP3R) Ca2+ signaling.
Volume: 108
Issue: 32
Pages: 13293-8
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Publication
34842276 | J:324405
 
First Author: Barthelson K
Year: 2022
Journal: Dis Model Mech
Title: Brain transcriptomes of zebrafish and mouse Alzheimer's disease knock-in models imply early disrupted energy metabolism.
Volume: 15
Issue: 1
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Publication
25218961 | J:217628
 
First Author: Hascalovici JR
Year: 2014
Journal: Neuroscience
Title: Neural HO-1/sterol interactions in vivo: implications for Alzheimer's disease.
Volume: 280
Pages: 40-9
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Publication
33758207 | J:304921
First Author: Oka S
Year: 2021
Journal: Sci Rep
Title: MTH1 and OGG1 maintain a low level of 8-oxoguanine in Alzheimer's brain, and prevent the progression of Alzheimer's pathogenesis.
Volume: 11
Issue: 1
Pages: 5819
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Publication
25024332 | J:357992
First Author: Rodriguez-Ortiz CJ
Year: 2014
Journal: J Alzheimers Dis
Title: Upregulation of miR-181 decreases c-Fos and SIRT-1 in the hippocampus of 3xTg-AD mice.
Volume: 42
Issue: 4
Pages: 1229-38
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Publication
31797996 | J:287531
First Author: Bourne KZ
Year: 2019
Journal: Sci Rep
Title: Suppressing aberrant phospholipase D1 signaling in 3xTg Alzheimer's disease mouse model promotes synaptic resilience.
Volume: 9
Issue: 1
Pages: 18342
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Publication
25224257 | J:325317
First Author: Shahani N
Year: 2015
Journal: Mol Psychiatry
Title: DISC1 regulates trafficking and processing of APP and Aβ generation.
Volume: 20
Issue: 7
Pages: 874-9
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Publication
36919893 | J:350716
First Author: Sonoda R
Year: 2023
Journal: J Dent Res
Title: Reduced Autophagy in Aged Trigeminal Neurons Causes Amyloid β Diffusion.
Volume: 102
Issue: 8
Pages: 938-946
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Publication
27189884 | J:235964
 
First Author: Michalski D
Year: 2016
Journal: Neuroscience
Title: Decline of microtubule-associated protein tau after experimental stroke in differently aged wild-type and 3xTg mice with Alzheimer-like alterations.
Volume: 330
Pages: 1-11
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Publication
22960314 | J:192478
 
First Author: Algarzae N
Year: 2012
Journal: Neuroscience
Title: Parkin prevents cortical atrophy and Aβ-induced alterations of brain metabolism: ¹³C NMR and magnetic resonance imaging studies in AD models.
Volume: 225
Pages: 22-34
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Publication
34879266 | J:321535
First Author: Han J
Year: 2021
Journal: Cell Rep
Title: Aberrant role of pyruvate kinase M2 in the regulation of gamma-secretase and memory deficits in Alzheimer's disease.
Volume: 37
Issue: 10
Pages: 110102
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12431992 | J:81726
First Author: Herms J
Year: 2003
Journal: J Biol Chem
Title: Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein.
Volume: 278
Issue: 4
Pages: 2484-9
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Publication
22926141 | J:188922
First Author: Manczak M
Year: 2012
Journal: Hum Mol Genet
Title: Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease.
Volume: 21
Issue: 23
Pages: 5131-46
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Publication
38750512 | J:352622
First Author: Zhang N
Year: 2024
Journal: Alzheimers Res Ther
Title: Cholecystokinin B receptor agonists alleviates anterograde amnesia in cholecystokinin-deficient and aged Alzheimer's disease mice.
Volume: 16
Issue: 1
Pages: 109
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Publication
36843263 | J:338361
First Author: Kim SH
Year: 2023
Journal: Autophagy
Title: Endolysosomal impairment by binding of amyloid beta or MAPT/Tau to V-ATPase and rescue via the HYAL-CD44 axis in Alzheimer disease.
Volume: 19
Issue: 8
Pages: 2318-2337
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Publication
30525042 | J:268837
 
First Author: Sabbir MG
Year: 2018
Journal: Front Mol Biosci
Title: Loss of Ca2+/Calmodulin Dependent Protein Kinase Kinase 2 Leads to Aberrant Transferrin Phosphorylation and Trafficking: A Potential Biomarker for Alzheimer's Disease.
Volume: 5
Pages: 99
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Publication
21235806 | J:194454
First Author: Fonseca MI
Year: 2011
Journal: J Neuroinflammation
Title: Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease.
Volume: 8
Issue: 1
Pages: 4
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Publication
29358916 | J:310530
 
First Author: Yang S
Year: 2017
Journal: Front Aging Neurosci
Title: Reducing the Levels of Akt Activation by PDK1 Knock-in Mutation Protects Neuronal Cultures against Synthetic Amyloid-Beta Peptides.
Volume: 9
Pages: 435
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Publication
21704011 | J:174403
First Author: Medeiros R
Year: 2011
Journal: Am J Pathol
Title: Loss of muscarinic M1 receptor exacerbates Alzheimer's disease-like pathology and cognitive decline.
Volume: 179
Issue: 2
Pages: 980-91
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Publication
27155503 | J:242424
First Author: Hargis KE
Year: 2017
Journal: Behav Brain Res
Title: Transcriptional signatures of brain aging and Alzheimer's disease: What are our rodent models telling us?
Volume: 322
Issue: Pt B
Pages: 311-328
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Publication
25002035 | J:218071
First Author: Orre M
Year: 2014
Journal: Neurobiol Aging
Title: Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction.
Volume: 35
Issue: 12
Pages: 2746-2760
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Publication
23432034 | J:199628
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Journal: Glia
Title: A single-cell analysis reveals multiple roles of oligodendroglial lineage cells during post-ischemic regeneration.
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Journal: Front Cell Dev Biol
Title: Tetramethylpyrazine Improves Cognitive Impairment and Modifies the Hippocampal Proteome in Two Mouse Models of Alzheimer's Disease.
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Title: The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer's and Huntington's diseases.
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