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Search results 701 to 774 out of 774 for Rax

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Hits by Pathway

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Hits by Strain

Type Details Score
Allele
Rax<tm1.1(rTA,tetO-cre)Lan> | MGI:5494255
Name: retina and anterior neural fold homeobox; targeted mutation 1.1, Richard A Lang
Allele Type: Targeted
Attribute String: Inducible, Recombinase, Transactivator
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Strain
MGI:5562437 | B6.Cg-Tg(Rax-cre)1Zkoz/Ph
Attribute String: transgenic, mutant strain, congenic
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Strain
MGI:5603595 | STOCK Rax<tm1.1(cre/ERT2)Sbls>/J
Attribute String: targeted mutation, mutant stock
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Genotype
Genotype
Symbol: Pax6/Pax6 Tg(Rax-cre)1Zkoz/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rax/Rax<+>
Background: involves: 129S6/SvEvTac
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rax/?
Background: involves: 129/Sv * C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rax/Rax<+> Yap1/Yap1
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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Publication
31634395 | J:280641
First Author: Shu W
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: Iron Accumulates in Retinal Vascular Endothelial Cells But Has Minimal Retinal Penetration After IP Iron Dextran Injection in Mice.
Volume: 60
Issue: 13
Pages: 4378-4387
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Publication
37048108 | J:335074
 
First Author: Kuzelova A
Year: 2023
Journal: Cells
Title: Chromatin Remodeling Enzyme Snf2h Is Essential for Retinal Cell Proliferation and Photoreceptor Maintenance.
Volume: 12
Issue: 7
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Rax-cre)1Zkoz/?
Background: involves: 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Publication
8944018 | J:36998
First Author: Semina EV
Year: 1996
Journal: Nat Genet
Title: Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome.
Volume: 14
Issue: 4
Pages: 392-9
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Publication
9466998 | J:46366
First Author: Semina EV
Year: 1998
Journal: Hum Mol Genet
Title: A new human homeobox gene OGI2X is a member of the most conserved homeobox gene family and is expressed during heart development in mouse.
Volume: 7
Issue: 3
Pages: 415-22
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Protein
Q920D1
Organism: Mus musculus/domesticus
Length: 161  
Fragment?: true
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Publication
9140395 | -
First Author: Rao E
Year: 1997
Journal: Nat Genet
Title: Pseudoautosomal deletions encompassing a novel homeobox gene cause growth failure in idiopathic short stature and Turner syndrome.
Volume: 16
Issue: 1
Pages: 54-63
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Publication
9482887 | J:46707
First Author: Eggert T
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Isolation of a Drosophila homolog of the vertebrate homeobox gene Rx and its possible role in brain and eye development.
Volume: 95
Issue: 5
Pages: 2343-8
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Protein Domain
IPR003654 | OAR_dom
Type: Domain
Description: This 14 amino acid motif has been identified within the C-terminal region of several paired-like homeodomain (HD) containing proteins [, ]. It was named OAR domain after the initials of otp, aristaless, and rax []. Although it has been proposed that this domain could be important for transactivation and be involved in protein-protein interactions or DNA binding [, ], its function is not yet known. Some proteins known to contain a OAR domain include human RIEG, defects in which are the cause of Rieger syndrome []; human OG12X and Mus musculus (Mouse) Og12x, whose function is not yet known []; vertebrate Rax, which plays a role in the proliferation and/or differentiation of retinal cells []; Drosophila DRX, which appears to be important in brain development []; and human SHOX, encoded by the short stature homeobox-containing gene.
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Publication
35202704 | J:324685
 
First Author: Liu Y
Year: 2022
Journal: Exp Eye Res
Title: Minimal effect of conditional ferroportin KO in the neural retina implicates ferrous iron in retinal iron overload and degeneration.
Volume: 218
Pages: 108988
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Genotype
Genotype
Symbol: Pax6/Pax6 Tg(Rax-cre)1Zkoz/?
Background: involves: 102/El * C3H/Rl
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Rax-cre)1Zkoz/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Rax/Rax<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCr
Zygosity: cn
Has Mutant Allele: true
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Publication
10336432 | J:55431
First Author: Ito T
Year: 1999
Journal: J Biol Chem
Title: RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling.
Volume: 274
Issue: 22
Pages: 15427-32
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Publication
22194846 | J:185991
First Author: Dickerman BK
Year: 2011
Journal: PLoS One
Title: Missense mutation in the second RNA binding domain reveals a role for Prkra (PACT/RAX) during skull development.
Volume: 6
Issue: 12
Pages: e28537
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Publication
36595695 | J:333384
First Author: Kim J
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Neighbor-specific gene expression revealed from physically interacting cells during mouse embryonic development.
Volume: 120
Issue: 2
Pages: e2205371120
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Protein
Q920D0
Organism: Mus musculus/domesticus
Length: 181  
Fragment?: true
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Protein
A0A494B9Q2
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: true
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Protein
A0A494BBH8
Organism: Mus musculus/domesticus
Length: 164  
Fragment?: true
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Protein
Q920C9
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: true
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Protein
O35602
Organism: Mus musculus/domesticus
Length: 342  
Fragment?: false
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Protein
Q9D8E1
Organism: Mus musculus/domesticus
Length: 118  
Fragment?: false
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Publication
26414443 | J:249118
First Author: Dickerman BK
Year: 2015
Journal: FEBS J
Title: The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development.
Volume: 282
Issue: 24
Pages: 4766-81
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Publication
35271829 | J:324683
 
First Author: Zhang KR
Year: 2022
Journal: Exp Eye Res
Title: Conditional knockout of hephaestin in the neural retina disrupts retinal iron homeostasis.
Volume: 218
Pages: 109028
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Publication
31287995 | J:280639
First Author: Baumann BH
Year: 2019
Journal: Am J Pathol
Title: Liver-Specific, but Not Retina-Specific, Hepcidin Knockout Causes Retinal Iron Accumulation and Degeneration.
Volume: 189
Issue: 9
Pages: 1814-1830
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Publication
25794677 | J:222438
First Author: Klimova L
Year: 2015
Journal: Dev Biol
Title: Onecut1 and Onecut2 transcription factors operate downstream of Pax6 to regulate horizontal cell development.
Volume: 402
Issue: 1
Pages: 48-60
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Publication
37287644 | J:359084
 
First Author: Linne C
Year: 2023
Journal: Mol Vis
Title: Encephalopsin (OPN3) is required for normal refractive development and the GO/GROW response to induced myopia.
Volume: 29
Pages: 39-57
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Publication
39284539 | J:354796
 
First Author: Cho SH
Year: 2024
Journal: Dev Biol
Title: Perturbed cell cycle phase-dependent positioning and nuclear migration of retinal progenitors along the apico-basal axis underlie global retinal disorganization in the LCA8-like mouse model.
Volume: 517
Pages: 39-54
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Genotype
Genotype
Symbol: Opn3/Opn3 Tg(Rax-cre)1Zkoz/?
Background: involves: C57BL/6N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Meis1/Meis1 Meis2/Meis2 Tg(Rax-cre)1Zkoz/?
Background: involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * C57BL/6N
Zygosity: cn
Has Mutant Allele: true
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Publication
23667567 | J:198990
First Author: Klimova L
Year: 2013
Journal: PLoS One
Title: Generation of mRx-Cre transgenic mouse line for efficient conditional gene deletion in early retinal progenitors.
Volume: 8
Issue: 5
Pages: e63029
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Publication
37751417 | J:341148
First Author: Bosze B
Year: 2023
Journal: PLoS Genet
Title: Notch pathway mutants do not equivalently perturb mouse embryonic retinal development.
Volume: 19
Issue: 9
Pages: e1010928
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Publication
33723039 | J:304642
 
First Author: Dupacova N
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Meis homeobox genes control progenitor competence in the retina.
Volume: 118
Issue: 12
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Publication
39142280 | J:353790
     
First Author: D'Souza SP
Year: 2024
Journal: Dev Cell
Title: Developmental control of rod number via a light-dependent retrograde pathway from intrinsically photosensitive retinal ganglion cells.
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Protein
Q8C8B0
Organism: Mus musculus/domesticus
Length: 326  
Fragment?: false
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Protein
O35137
Organism: Mus musculus/domesticus
Length: 399  
Fragment?: false
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Protein
Q8BYH0
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: false
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Protein
P97474
Organism: Mus musculus/domesticus
Length: 317  
Fragment?: false
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Protein
Q06348
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: false
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Protein
P70314
Organism: Mus musculus/domesticus
Length: 315  
Fragment?: false
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Protein
Q91ZK4
Organism: Mus musculus/domesticus
Length: 381  
Fragment?: false
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Protein
O35085
Organism: Mus musculus/domesticus
Length: 564  
Fragment?: false
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Protein
O09113
Organism: Mus musculus/domesticus
Length: 325  
Fragment?: false
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Protein
P63013
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: false
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Protein
P70390
Organism: Mus musculus/domesticus
Length: 331  
Fragment?: false
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Protein
O35160
Organism: Mus musculus/domesticus
Length: 302  
Fragment?: false
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Protein
Q61412
Organism: Mus musculus/domesticus
Length: 361  
Fragment?: false
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Protein
Q3UM84
Organism: Mus musculus/domesticus
Length: 222  
Fragment?: true
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Protein
Q80WF9
Organism: Mus musculus/domesticus
Length: 361  
Fragment?: false
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Protein
Q6PDC1
Organism: Mus musculus/domesticus
Length: 380  
Fragment?: false
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Protein
A0A140T8S9
Organism: Mus musculus/domesticus
Length: 190  
Fragment?: false
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Protein
Q9CY80
Organism: Mus musculus/domesticus
Length: 175  
Fragment?: false
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Protein
Q3UQH0
Organism: Mus musculus/domesticus
Length: 315  
Fragment?: false
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Protein
F6UTR6
Organism: Mus musculus/domesticus
Length: 240  
Fragment?: true
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Protein
B1VD85
Organism: Mus musculus/domesticus
Length: 290  
Fragment?: false
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Protein
A0A1W2P8B9
Organism: Mus musculus/domesticus
Length: 377  
Fragment?: false
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Protein
B1VD84
Organism: Mus musculus/domesticus
Length: 304  
Fragment?: false
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Protein
Q6DIA6
Organism: Mus musculus/domesticus
Length: 324  
Fragment?: false
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Protein
A2APZ7
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: false
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Publication
31145883 | J:279263
First Author: Cho SH
Year: 2019
Journal: Dev Biol
Title: Targeted deletion of Crb1/Crb2 in the optic vesicle models key features of leber congenital amaurosis 8.
Volume: 453
Issue: 2
Pages: 141-154
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Publication
37923392 | J:342361
 
First Author: Wu SR
Year: 2023
Journal: eNeuro
Title: The Atoh1-Cre Knock-In Allele Ectopically Labels a Subpopulation of Amacrine Cells and Bipolar Cells in Mouse Retina.
Volume: 10
Issue: 11
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Publication
34677125 | J:314167
   
First Author: Lim S
Year: 2021
Journal: Elife
Title: mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia.
Volume: 10
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Publication
33135183 | J:322005
First Author: Parmhans N
Year: 2021
Journal: J Comp Neurol
Title: Identification of retinal ganglion cell types and brain nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock-in allele.
Volume: 529
Issue: 8
Pages: 1926-1953
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Publication
31968245 | J:287419
First Author: Nayak G
Year: 2020
Journal: Cell Rep
Title: Adaptive Thermogenesis in Mice Is Enhanced by Opsin 3-Dependent Adipocyte Light Sensing.
Volume: 30
Issue: 3
Pages: 672-686.e8
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Protein
P47239
Organism: Mus musculus/domesticus
Length: 503  
Fragment?: false
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Protein
G3UX36
Organism: Mus musculus/domesticus
Length: 505  
Fragment?: false
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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