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Search results 701 to 800 out of 1044 for Rel

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Type Details Score
Publication
First Author: Minakhina S
Year: 2003
Journal: Genes Cells
Title: Tamo selectively modulates nuclear import in Drosophila.
Volume: 8
Issue: 4
Pages: 299-310
Protein Domain
Type: Family
Description: Protein tamozhennic (means 'customs officer' in Russian, also known as Tamo) has an essential role during oogenesis and embryogenesis. Tamo interacts with Dorsal and proteins of the nuclear import machinery. Translocation of the Rel protein Dorsal from the cytoplasm to the nucleus in a graded manner directs the development of the dorsal-ventral axis in Drosophila. Tamo is likely to have a role in nuclear import of Dorsal and other proteins [].
Publication
First Author: Molkentin JD
Year: 1998
Journal: Cell
Title: A calcineurin-dependent transcriptional pathway for cardiac hypertrophy.
Volume: 93
Issue: 2
Pages: 215-28
Publication
First Author: Burkly L
Year: 1995
Journal: Nature
Title: Expression of relB is required for the development of thymic medulla and dendritic cells.
Volume: 373
Issue: 6514
Pages: 531-6
Publication
First Author: Yao Z
Year: 2014
Journal: J Bone Miner Res
Title: NF-κB RelB negatively regulates osteoblast differentiation and bone formation.
Volume: 29
Issue: 4
Pages: 866-77
Publication
First Author: Horsley V
Year: 2003
Journal: Cell
Title: IL-4 acts as a myoblast recruitment factor during mammalian muscle growth.
Volume: 113
Issue: 4
Pages: 483-94
Publication
First Author: Daou N
Year: 2013
Journal: Development
Title: A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis.
Volume: 140
Issue: 24
Pages: 4914-25
Publication
First Author: dos Santos NR
Year: 2008
Journal: PLoS One
Title: RelB-dependent stromal cells promote T-cell leukemogenesis.
Volume: 3
Issue: 7
Pages: e2555
Publication
First Author: Weih F
Year: 1997
Journal: J Exp Med
Title: p50-NF-kappaB complexes partially compensate for the absence of RelB: severely increased pathology in p50(-/-)relB(-/-) double-knockout mice.
Volume: 185
Issue: 7
Pages: 1359-70
Strain
Attribute String: transgenic, mutant strain, coisogenic
Strain
Attribute String: mutant strain, transgenic
Publication
First Author: Lo D
Year: 1992
Journal: Am J Pathol
Title: A recessive defect in lymphocyte or granulocyte function caused by an integrated transgene.
Volume: 141
Issue: 5
Pages: 1237-46
Publication  
First Author: Pareek S
Year: 2019
Journal: Mol Immunol
Title: Pulmonary neutrophilia caused by absence of the NF-κB member RelB is dampened by exposure to cigarette smoke.
Volume: 114
Pages: 395-409
Publication
First Author: Guerin S
Year: 2002
Journal: Eur J Immunol
Title: RelB reduces thymocyte apoptosis and regulates terminal thymocyte maturation.
Volume: 32
Issue: 1
Pages: 1-9
Publication
First Author: Tan JK
Year: 2007
Journal: Exp Hematol
Title: Hematopoiesis of immature myeloid dendritic cells in stroma-dependent spleen long-term cultures occurs independently of NF-KB/RelB function.
Volume: 35
Issue: 10
Pages: 1580-93
Publication
First Author: MacDonald KP
Year: 2007
Journal: Blood
Title: Effector and regulatory T-cell function is differentially regulated by RelB within antigen-presenting cells during GVHD.
Volume: 109
Issue: 11
Pages: 5049-57
Publication
First Author: Wu L
Year: 1998
Journal: Immunity
Title: RelB is essential for the development of myeloid-related CD8alpha- dendritic cells but not of lymphoid-related CD8alpha+ dendritic cells.
Volume: 9
Issue: 6
Pages: 839-47
Publication
First Author: Martucci C
Year: 2007
Journal: J Leukoc Biol
Title: Differential involvement of RelB in morphine-induced modulation of chemotaxis, NO, and cytokine production in murine macrophages and lymphocytes.
Volume: 81
Issue: 1
Pages: 344-54
Publication
First Author: Xia Y
Year: 1999
Journal: Mol Cell Biol
Title: RelB modulation of IkappaBalpha stability as a mechanism of transcription suppression of interleukin-1alpha (IL-1alpha), IL-1beta, and tumor necrosis factor alpha in fibroblasts.
Volume: 19
Issue: 11
Pages: 7688-96
Publication  
First Author: Nakatomi C
Year: 2019
Journal: Bone
Title: Constitutive activation of the alternative NF-κB pathway disturbs endochondral ossification.
Volume: 121
Pages: 29-41
Publication
First Author: Quadrato G
Year: 2014
Journal: J Neurosci
Title: Modulation of GABAA receptor signaling increases neurogenesis and suppresses anxiety through NFATc4.
Volume: 34
Issue: 25
Pages: 8630-45
Publication
First Author: Go WY
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: NFAT5/TonEBP mutant mice define osmotic stress as a critical feature of the lymphoid microenvironment.
Volume: 101
Issue: 29
Pages: 10673-8
Publication  
First Author: Tessier S
Year: 2020
Journal: Matrix Biol
Title: TonEBP-deficiency accelerates intervertebral disc degeneration underscored by matrix remodeling, cytoskeletal rearrangements, and changes in proinflammatory gene expression.
Volume: 87
Pages: 94-111
Publication  
First Author: Lee JH
Year: 2015
Journal: Sci Rep
Title: TonEBP suppresses adipogenesis and insulin sensitivity by blocking epigenetic transition of PPARγ2.
Volume: 5
Pages: 10937
Publication
First Author: Johnson ZI
Year: 2016
Journal: J Biol Chem
Title: RNA Sequencing Reveals a Role of TonEBP Transcription Factor in Regulation of Pro-inflammatory Genes in Response to Hyperosmolarity in Healthy Nucleus Pulposus Cells: A HOMEOSTATIC RESPONSE?
Volume: 291
Issue: 52
Pages: 26686-26697
Publication
First Author: O'Connor RS
Year: 2007
Journal: J Cell Sci
Title: A combinatorial role for NFAT5 in both myoblast migration and differentiation during skeletal muscle myogenesis.
Volume: 120
Issue: Pt 1
Pages: 149-59
Publication  
First Author: Yoo EJ
Year: 2019
Journal: Front Immunol
Title: TonEBP Suppresses the HO-1 Gene by Blocking Recruitment of Nrf2 to Its Promoter.
Volume: 10
Pages: 850
Publication
First Author: Lee S
Year: 2018
Journal: J Immunol
Title: Transcription Factor NFAT5 Promotes Migration and Invasion of Rheumatoid Synoviocytes via Coagulation Factor III and CCL2.
Volume: 201
Issue: 2
Pages: 359-370
Publication
First Author: Choi S
Year: 2017
Journal: J Clin Invest
Title: Transcription factor NFAT5 promotes macrophage survival in rheumatoid arthritis.
Volume: 127
Issue: 3
Pages: 954-969
Publication  
First Author: Gwon DH
Year: 2021
Journal: Int J Mol Sci
Title: NFAT5 Deficiency Alleviates Formalin-Induced Inflammatory Pain Through mTOR.
Volume: 22
Issue: 5
Publication
First Author: Shin HJ
Year: 2014
Journal: Cell Death Differ
Title: Tonicity-responsive enhancer binding protein haplodeficiency attenuates seizure severity and NF-κB-mediated neuroinflammation in kainic acid-induced seizures.
Volume: 21
Issue: 7
Pages: 1095-106
Publication
First Author: Choi H
Year: 2018
Journal: J Biol Chem
Title: COX-2 expression mediated by calcium-TonEBP signaling axis under hyperosmotic conditions serves osmoprotective function in nucleus pulposus cells.
Volume: 293
Issue: 23
Pages: 8969-8981
Publication
First Author: Kim HR
Year: 2019
Journal: FEBS Lett
Title: Tonicity-responsive enhancer binding protein (TonEBP) regulates TNF-α-induced hypothalamic inflammation.
Volume: 593
Issue: 19
Pages: 2762-2770
Publication
First Author: Lee JY
Year: 2017
Journal: Sci Rep
Title: TonEBP/NFAT5 haploinsufficiency attenuates hippocampal inflammation in high-fat diet/streptozotocin-induced diabetic mice.
Volume: 7
Issue: 1
Pages: 7837
Publication
First Author: Liu C
Year: 2017
Journal: Sci Rep
Title: Lack of evidence for involvement of TonEBP and hyperosmotic stimulus in induction of autophagy in the nucleus pulposus.
Volume: 7
Issue: 1
Pages: 4543
Publication  
First Author: Park J
Year: 2014
Journal: Exp Eye Res
Title: Tonicity-responsive enhancer binding protein regulates the expression of aldose reductase and protein kinase C δ in a mouse model of diabetic retinopathy.
Volume: 122
Pages: 13-9
Publication
First Author: Snuggs JW
Year: 2021
Journal: Sci Rep
Title: TonEBP regulates the hyperosmotic expression of aquaporin 1 and 5 in the intervertebral disc.
Volume: 11
Issue: 1
Pages: 3164
Publication
First Author: Gillis AM
Year: 2004
Journal: Cardiovasc Res
Title: Heart block in mice overexpressing calcineurin but not NF-AT3.
Volume: 64
Issue: 3
Pages: 488-95
Genotype
Symbol: Nfat5/Nfat5
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Nfat5/Nfat5<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Relb/Relb
Background: C57BL/6-Relb
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Relb/Relb<+>
Background: involves: C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Relb/Relb
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 55  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 83  
Fragment?: false
Publication
First Author: Yen H
Year: 2010
Journal: PLoS Pathog
Title: NleC, a type III secretion protease, compromises NF-κB activation by targeting p65/RelA.
Volume: 6
Issue: 12
Pages: e1001231
Publication
First Author: Iuso A
Year: 2014
Journal: PLoS One
Title: Impairment of Drosophila orthologs of the human orphan protein C19orf12 induces bang sensitivity and neurodegeneration.
Volume: 9
Issue: 2
Pages: e89439
Publication  
First Author: Venco P
Year: 2015
Journal: Front Genet
Title: Mutations of C19orf12, coding for a transmembrane glycine zipper containing mitochondrial protein, cause mis-localization of the protein, inability to respond to oxidative stress and increased mitochondrial Ca²⁺.
Volume: 6
Pages: 185
Publication
First Author: Gagliardi M
Year: 2015
Journal: Parkinsonism Relat Disord
Title: C19orf12 gene mutations in patients with neurodegeneration with brain iron accumulation.
Volume: 21
Issue: 7
Pages: 813-6
Publication
First Author: Goto A
Year: 2018
Journal: Immunity
Title: The Kinase IKKβ Regulates a STING- and NF-κB-Dependent Antiviral Response Pathway in Drosophila.
Volume: 49
Issue: 2
Pages: 225-234.e4
Protein Domain
Type: Family
Description: This family of bacterial metallo-peptidases is thought to compromise the inflammatory response by degrading p65, thereby down-regulating the NF-kappaB signalling pathway []. NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52; and the heterodimeric p65-p50 complex appears to be most abundant one.
Protein Domain
Type: Family
Description: C19orf12 codes for a transmembrane glycine zipper-containing mitochondrial protein of unknown function. Mutations of C19orf12 cause inability to respond to oxidative stress and increased mitochondrial Ca2+ []. Mutations in C19orf12 have been identified in patients affected by Neurodegeneration with Brain Iron Accumulation (NBIA), a condition characterised by iron accumulation in the basal ganglia []. Transgenic flies with impaired C19orf12 homologues also show the neurodegenerative phenotype []. This family also includes protein Nazo from Drosophila melanogaster, an orthologue of human C190rf12 which functions as an antiviral effector protein expressed downstream of Sting and Rel (Relish) signalling in response to viral infection [].
Publication
First Author: Thompson JE
Year: 1995
Journal: Cell
Title: I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B.
Volume: 80
Issue: 4
Pages: 573-82
Publication
First Author: Dobrzanski P
Year: 1993
Journal: Mol Cell Biol
Title: Both N- and C-terminal domains of RelB are required for full transactivation: role of the N-terminal leucine zipper-like motif.
Volume: 13
Issue: 3
Pages: 1572-82
Publication
First Author: Yamamoto Y
Year: 2003
Journal: Nature
Title: Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression.
Volume: 423
Issue: 6940
Pages: 655-9
Publication
First Author: Hodge MR
Year: 1996
Journal: Science
Title: NF-AT-Driven interleukin-4 transcription potentiated by NIP45.
Volume: 274
Issue: 5294
Pages: 1903-5
Publication
First Author: Hu CJ
Year: 2001
Journal: Immunity
Title: PU.1/Spi-B regulation of c-rel is essential for mature B cell survival.
Volume: 15
Issue: 4
Pages: 545-55
Publication
First Author: Kinoshita D
Year: 2006
Journal: J Immunol
Title: Essential role of IkappaB kinase alpha in thymic organogenesis required for the establishment of self-tolerance.
Volume: 176
Issue: 7
Pages: 3995-4002
Publication
First Author: Alcamo E
Year: 2002
Journal: J Exp Med
Title: Requirement for the NF-kappaB family member RelA in the development of secondary lymphoid organs.
Volume: 195
Issue: 2
Pages: 233-44
Publication
First Author: Kajiura F
Year: 2004
Journal: J Immunol
Title: NF-kappa B-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner.
Volume: 172
Issue: 4
Pages: 2067-75
Publication
First Author: Cao S
Year: 2006
Journal: J Biol Chem
Title: NF-kappaB1 (p50) homodimers differentially regulate pro- and anti-inflammatory cytokines in macrophages.
Volume: 281
Issue: 36
Pages: 26041-50
Publication
First Author: Ye BJ
Year: 2020
Journal: Cell Death Dis
Title: TonEBP in dendritic cells mediates pro-inflammatory maturation and Th1/Th17 responses.
Volume: 11
Issue: 6
Pages: 421
Publication
First Author: Lambrecht R
Year: 2023
Journal: Cell Rep
Title: Liver receptor homolog-1 (NR5A2) orchestrates hepatic inflammation and TNF-induced cell death.
Volume: 42
Issue: 12
Pages: 113513
Publication
First Author: Piffat KA
Year: 2001
Journal: Mol Cell Biol Res Commun
Title: The chicken RelB transcription factor has transactivation sequences and a tissue-specific expression pattern that are distinct from mammalian RelB.
Volume: 4
Issue: 5
Pages: 266-75
Publication
First Author: Wulczyn FG
Year: 1992
Journal: Nature
Title: Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappa B.
Volume: 358
Issue: 6387
Pages: 597-9
Publication
First Author: Hoey T
Year: 1995
Journal: Immunity
Title: Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins.
Volume: 2
Issue: 5
Pages: 461-72
Publication
First Author: Savinova OV
Year: 2009
Journal: Mol Cell
Title: The Nfkb1 and Nfkb2 proteins p105 and p100 function as the core of high-molecular-weight heterogeneous complexes.
Volume: 34
Issue: 5
Pages: 591-602
Publication  
First Author: Tsui R
Year: 2015
Journal: Nat Commun
Title: IκBβ enhances the generation of the low-affinity NFκB/RelA homodimer.
Volume: 6
Pages: 7068
Publication
First Author: Wilkins BJ
Year: 2002
Journal: Mol Cell Biol
Title: Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth.
Volume: 22
Issue: 21
Pages: 7603-13
Publication
First Author: Kobayashi T
Year: 2003
Journal: Immunity
Title: TRAF6 is a critical factor for dendritic cell maturation and development.
Volume: 19
Issue: 3
Pages: 353-63
Publication
First Author: Vaira S
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: RelB is the NF-kappaB subunit downstream of NIK responsible for osteoclast differentiation.
Volume: 105
Issue: 10
Pages: 3897-902
Publication  
First Author: Halterman JA
Year: 2012
Journal: Front Physiol
Title: NFAT5 expression in bone marrow-derived cells enhances atherosclerosis and drives macrophage migration.
Volume: 3
Pages: 313
Publication
First Author: Elewaut D
Year: 2003
Journal: J Exp Med
Title: NIK-dependent RelB activation defines a unique signaling pathway for the development of V alpha 14i NKT cells.
Volume: 197
Issue: 12
Pages: 1623-33
Publication
First Author: Eigenbrod T
Year: 2013
Journal: J Immunol
Title: Early inhibition of IL-1β expression by IFN-γ is mediated by impaired binding of NF-κB to the IL-1β promoter but is independent of nitric oxide.
Volume: 190
Issue: 12
Pages: 6533-41
Publication
First Author: Rengarajan J
Year: 2002
Journal: Nat Immunol
Title: NFATc2 and NFATc3 regulate T(H)2 differentiation and modulate TCR-responsiveness of naïve T(H)cells.
Volume: 3
Issue: 1
Pages: 48-54
Publication
First Author: Weigmann B
Year: 2008
Journal: J Exp Med
Title: The transcription factor NFATc2 controls IL-6-dependent T cell activation in experimental colitis.
Volume: 205
Issue: 9
Pages: 2099-110
Publication
First Author: Armand AS
Year: 2008
Journal: J Biol Chem
Title: Cooperative synergy between NFAT and MyoD regulates myogenin expression and myogenesis.
Volume: 283
Issue: 43
Pages: 29004-10
Publication
First Author: Weih F
Year: 1996
Journal: J Immunol
Title: Both multiorgan inflammation and myeloid hyperplasia in RelB-deficient mice are T cell dependent.
Volume: 157
Issue: 9
Pages: 3974-9
Publication
First Author: Paxian S
Year: 2002
Journal: Gastroenterology
Title: Abnormal organogenesis of Peyer's patches in mice deficient for NF-kappaB1, NF-kappaB2, and Bcl-3.
Volume: 122
Issue: 7
Pages: 1853-68
Publication
First Author: de Souza AR
Year: 2014
Journal: Toxicol Sci
Title: Aryl hydrocarbon receptor (AhR) attenuation of subchronic cigarette smoke-induced pulmonary neutrophilia is associated with retention of nuclear RelB and suppression of intercellular adhesion molecule-1 (ICAM-1).
Volume: 140
Issue: 1
Pages: 204-23
Publication
First Author: Heineke J
Year: 2010
Journal: J Mol Cell Cardiol
Title: Calcineurin protects the heart in a murine model of dilated cardiomyopathy.
Volume: 48
Issue: 6
Pages: 1080-7
Publication
First Author: Ishimaru N
Year: 2006
Journal: Nat Immunol
Title: Regulation of naive T cell function by the NF-kappaB2 pathway.
Volume: 7
Issue: 7
Pages: 763-72
Publication
First Author: Soysa NS
Year: 2010
Journal: J Bone Miner Res
Title: The pivotal role of the alternative NF-kappaB pathway in maintenance of basal bone homeostasis and osteoclastogenesis.
Volume: 25
Issue: 4
Pages: 809-18
Publication
First Author: Zhao C
Year: 2012
Journal: Stem Cells
Title: Noncanonical NF-κB signaling regulates hematopoietic stem cell self-renewal and microenvironment interactions.
Volume: 30
Issue: 4
Pages: 709-18
Publication
First Author: Liang Q
Year: 2019
Journal: Am J Pathol
Title: Avian Reticuloendotheliosis Viral Oncogene Related B Regulates Lymphatic Endothelial Cells during Vessel Maturation and Is Required for Lymphatic Vessel Function in Adult Mice.
Volume: 189
Issue: 12
Pages: 2516-2530
Publication
First Author: Guo F
Year: 2007
Journal: Blood
Title: Constitutive alternative NF-kappaB signaling promotes marginal zone B-cell development but disrupts the marginal sinus and induces HEV-like structures in the spleen.
Volume: 110
Issue: 7
Pages: 2381-9
Publication
First Author: Mehta DS
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression.
Volume: 102
Issue: 6
Pages: 2016-21
Publication
First Author: Peng SL
Year: 2001
Journal: Immunity
Title: NFATc1 and NFATc2 together control both T and B cell activation and differentiation.
Volume: 14
Issue: 1
Pages: 13-20
Publication
First Author: Koga T
Year: 2005
Journal: Nat Med
Title: NFAT and Osterix cooperatively regulate bone formation.
Volume: 11
Issue: 8
Pages: 880-5
Publication
First Author: Asagiri M
Year: 2005
Journal: J Exp Med
Title: Autoamplification of NFATc1 expression determines its essential role in bone homeostasis.
Volume: 202
Issue: 9
Pages: 1261-9
Publication
First Author: Bopp T
Year: 2005
Journal: J Exp Med
Title: NFATc2 and NFATc3 transcription factors play a crucial role in suppression of CD4+ T lymphocytes by CD4+ CD25+ regulatory T cells.
Volume: 201
Issue: 2
Pages: 181-7
Publication
First Author: Samanta DN
Year: 2005
Journal: J Immunol
Title: B cell hyperresponsiveness and expansion of mature follicular B cells but not of marginal zone B cells in NFATc2/c3 double-deficient mice.
Volume: 174
Issue: 8
Pages: 4797-802
Publication
First Author: Rengarajan J
Year: 2000
Journal: Immunity
Title: Sequential involvement of NFAT and Egr transcription factors in FasL regulation.
Volume: 12
Issue: 3
Pages: 293-300
Publication
First Author: Glud SZ
Year: 2005
Journal: Blood
Title: A tumor-suppressor function for NFATc3 in T-cell lymphomagenesis by murine leukemia virus.
Volume: 106
Issue: 10
Pages: 3546-52
Publication
First Author: Ranger AM
Year: 1998
Journal: Immunity
Title: Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development.
Volume: 9
Issue: 5
Pages: 627-35
Publication
First Author: Yang TT
Year: 2006
Journal: Mol Cell Biol
Title: Role of transcription factor NFAT in glucose and insulin homeostasis.
Volume: 26
Issue: 20
Pages: 7372-87
Publication
First Author: Bourajjaj M
Year: 2008
Journal: J Biol Chem
Title: NFATc2 is a necessary mediator of calcineurin-dependent cardiac hypertrophy and heart failure.
Volume: 283
Issue: 32
Pages: 22295-303
Publication
First Author: Tessier S
Year: 2019
Journal: Dev Biol
Title: NFAT5/TonEBP controls early acquisition of notochord phenotypic markers, collagen composition, and sonic hedgehog signaling during mouse intervertebral disc embryogenesis.
Volume: 455
Issue: 2
Pages: 369-381
Publication
First Author: Lim HW
Year: 2000
Journal: J Mol Cell Cardiol
Title: Reversal of cardiac hypertrophy in transgenic disease models by calcineurin inhibition.
Volume: 32
Issue: 4
Pages: 697-709