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Search results 701 to 800 out of 818 for Ripk3

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Type Details Score
Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
33549745 | J:304097
First Author: Yañez MJ
Year: 2021
Journal: Biochim Biophys Acta Mol Basis Dis
Title: c-Abl activates RIPK3 signaling in Gaucher disease.
Volume: 1867
Issue: 5
Pages: 166089
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UniProt Feature
UniProt Feature
Begin: 161
Description: Phosphoserine; by RIPK3 and autocatalysis
Type: modified residue
End: 161
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Publication
36696505 | J:344576
First Author: Imanishi T
Year: 2023
Journal: Sci Adv
Title: RIPK1 blocks T cell senescence mediated by RIPK3 and caspase-8.
Volume: 9
Issue: 4
Pages: eadd6097
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Publication
33625952 | J:330413
First Author: Huang HR
Year: 2021
Journal: Am J Respir Cell Mol Biol
Title: RIPK3 Activates MLKL-mediated Necroptosis and Inflammasome Signaling during Streptococcus Infection.
Volume: 64
Issue: 5
Pages: 579-591
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Publication
37639745 | J:340642
 
First Author: Zhang J
Year: 2023
Journal: Biomed Pharmacother
Title: Regulatory mechanism of CaMKII δ mediated by RIPK3 on myocardial fibrosis and reversal effects of RIPK3 inhibitor GSK'872.
Volume: 166
Pages: 115380
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Publication
36604592 | J:355686
First Author: Lee SA
Year: 2023
Journal: Nat Cell Biol
Title: OASL phase condensation induces amyloid-like fibrillation of RIPK3 to promote virus-induced necroptosis.
Volume: 25
Issue: 1
Pages: 92-107
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Publication
35561683 | J:326202
First Author: Zhang L
Year: 2022
Journal: Stem Cell Reports
Title: Ripk3 signaling regulates HSCs during stress and represses radiation-induced leukemia in mice.
Volume: 17
Issue: 6
Pages: 1428-1441
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Publication
23892367 | J:229003
First Author: Dondelinger Y
Year: 2013
Journal: Cell Death Differ
Title: RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition.
Volume: 20
Issue: 10
Pages: 1381-92
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Publication
32433959 | J:292378
First Author: Zhang H
Year: 2020
Journal: Cell Rep
Title: Crucial Roles of the RIP Homotypic Interaction Motifs of RIPK3 in RIPK1-Dependent Cell Death and Lymphoproliferative Disease.
Volume: 31
Issue: 7
Pages: 107650
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Publication
37204757 | J:342083
First Author: Mohammed S
Year: 2023
Journal: Mol Cancer Res
Title: Absence of Either Ripk3 or Mlkl Reduces Incidence of Hepatocellular Carcinoma Independent of Liver Fibrosis.
Volume: 21
Issue: 9
Pages: 933-946
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Interaction Experiment
Matsuzawa Y (2015)
Description: RIPK3 regulates p62-LC3 complex formation via the caspase-8-dependent cleavage of p62.
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Allele
Ripk3<em2Smoc> | MGI:7292065
Name: receptor-interacting serine-threonine kinase 3; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6476184 | C57BL/6JSmoc-Ripk3<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Ripk3<tm1Smoc> | MGI:7292066
Name: receptor-interacting serine-threonine kinase 3; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Publication
32184955 | -
First Author: Hart AC
Year: 2020
Journal: ACS Med Chem Lett
Title: Identification of RIPK3 Type II Inhibitors Using High-Throughput Mechanistic Studies in Hit Triage.
Volume: 11
Issue: 3
Pages: 266-271
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Strain
MGI:7623474 | C57BL/6JSmoc-Ripk3<tm1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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GO Term
GO:0097342 | ripoptosome
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Allele
Gt(ROSA)26Sor<tm1(Ripk3)Aob> | MGI:5908548
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Andrew Oberst
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
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Allele
Mlkl<em1Najaf> | MGI:7550372
 
Name: mixed lineage kinase domain-like; endonuclease-mediated mutation 1, Ayaz Najafov
Allele Type: Endonuclease-mediated
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HT Experiment
E-MTAB-11540 | RNA-sequencing of lung RNA from mice with compound mutations in ADAR1 and MAVS, ZBP1 or RIPK3.
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Strain
MGI:7550373 | C57BL/6N-Mlkl<em1Najaf>/J
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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HT Experiment
GSE254754 | ZBP1 and TRIF trigger lethal necroptosis in mice lacking caspase-8 and TNFR1
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE200854 | ADAR1 mutation causes ZBP1-dependent immunopathology
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE125625 | CASP8 C362A KI MLKL KO e16.5 intestine RNAseq
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE132133 | Single cell RNA-seq of intestine from E18.5 Mlkl -/- and Casp8 C362A/C362A Mlkl -/- embryos
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
29073079 | J:289445
First Author: Koehler H
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of DAI-dependent necroptosis by the Z-DNA binding domain of the vaccinia virus innate immune evasion protein, E3.
Volume: 114
Issue: 43
Pages: 11506-11511
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Publication
26853145 | J:233034
First Author: Quarato G
Year: 2016
Journal: Mol Cell
Title: Sequential Engagement of Distinct MLKL Phosphatidylinositol-Binding Sites Executes Necroptosis.
Volume: 61
Issue: 4
Pages: 589-601
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Publication
38858387 | J:354558
First Author: Rucker AJ
Year: 2024
Journal: Cell Death Dis
Title: Necroptosis stimulates interferon-mediated protective anti-tumor immunity.
Volume: 15
Issue: 6
Pages: 403
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Publication
24095739 | J:203778
First Author: Weinlich R
Year: 2013
Journal: Cell Rep
Title: Protective roles for caspase-8 and cFLIP in adult homeostasis.
Volume: 5
Issue: 2
Pages: 340-8
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Publication
37352855 | J:338214
First Author: Lei Y
Year: 2023
Journal: Cell
Title: Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity.
Volume: 186
Issue: 14
Pages: 3013-3032.e22
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Publication
33510145 | J:314601
First Author: Moujalled D
Year: 2021
Journal: Cell Death Dis
Title: The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis.
Volume: 12
Issue: 1
Pages: 133
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Publication
31358971 | J:282927
First Author: Lee SB
Year: 2019
Journal: Nat Cell Biol
Title: The AMPK-Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome.
Volume: 21
Issue: 8
Pages: 940-951
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Publication
31914391 | J:288110
First Author: Wu K
Year: 2020
Journal: Cell Rep
Title: SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States.
Volume: 30
Issue: 1
Pages: 25-36.e6
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Publication
33147463 | J:306551
First Author: Mabe NW
Year: 2020
Journal: Cell Rep
Title: G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program.
Volume: 33
Issue: 5
Pages: 108341
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Publication
33523877 | J:348490
 
First Author: Park J
Year: 2021
Journal: Sci Adv
Title: O-GlcNAcylation ameliorates the pathological manifestations of Alzheimer's disease by inhibiting necroptosis.
Volume: 7
Issue: 3
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Publication
35101890 | J:322741
First Author: Kodali S
Year: 2022
Journal: J Immunol
Title: Protection of Quiescence and Longevity of IgG Memory B Cells by Mitochondrial Autophagy.
Volume: 208
Issue: 5
Pages: 1085-1098
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Publication
25195660 | J:229215
First Author: Kearney CJ
Year: 2014
Journal: FEBS J
Title: RIPK1 can function as an inhibitor rather than an initiator of RIPK3-dependent necroptosis.
Volume: 281
Issue: 21
Pages: 4921-34
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Publication
27050509 | J:234951
First Author: Aaes TL
Year: 2016
Journal: Cell Rep
Title: Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity.
Volume: 15
Issue: 2
Pages: 274-87
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Publication
28106882 | J:259265
First Author: Tanzer MC
Year: 2017
Journal: Cell Death Differ
Title: Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways.
Volume: 24
Issue: 3
Pages: 481-491
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Publication
32362323 | J:306381
First Author: Schwarzer R
Year: 2020
Journal: Immunity
Title: FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells.
Volume: 52
Issue: 6
Pages: 978-993.e6
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Publication
36471162 | J:341987
First Author: Murai S
Year: 2022
Journal: Commun Biol
Title: Generation of transgenic mice expressing a FRET biosensor, SMART, that responds to necroptosis.
Volume: 5
Issue: 1
Pages: 1331
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Publication
38744293 | J:349097
     
First Author: Imai T
Year: 2024
Journal: Immunity
Title: The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation.
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Publication
38750308 | J:361147
First Author: Chiou S
Year: 2024
Journal: EMBO Mol Med
Title: An immunohistochemical atlas of necroptotic pathway expression.
Volume: 16
Issue: 7
Pages: 1717-1749
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Publication
31748744 | J:285930
First Author: Fritsch M
Year: 2019
Journal: Nature
Title: Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis.
Volume: 575
Issue: 7784
Pages: 683-687
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Publication
30867408 | J:280188
First Author: Zhang X
Year: 2019
Journal: Cell Death Dis
Title: RIPK1 can mediate apoptosis in addition to necroptosis during embryonic development.
Volume: 10
Issue: 3
Pages: 245
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Publication
31827281 | J:285926
First Author: Lalaoui N
Year: 2020
Journal: Nature
Title: Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease.
Volume: 577
Issue: 7788
Pages: 103-108
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Publication
30786994 | J:274184
First Author: Jayakumar A
Year: 2019
Journal: Cancer Res
Title: RIPK3-Induced Inflammation by I-MDSCs Promotes Intestinal Tumors.
Volume: 79
Issue: 7
Pages: 1587-1599
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Publication
28860618 | J:256341
First Author: Lee SH
Year: 2017
Journal: Sci Rep
Title: Interferon-gamma regulates inflammatory cell death by targeting necroptosis in experimental autoimmune arthritis.
Volume: 7
Issue: 1
Pages: 10133
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Publication
30862875 | J:275911
First Author: Berkhout L
Year: 2019
Journal: Sci Rep
Title: Deletion of tumour necrosis factor α receptor 1 elicits an increased TH17 immune response in the chronically inflamed liver.
Volume: 9
Issue: 1
Pages: 4232
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Publication
33288903 | J:302759
     
First Author: Li C
Year: 2020
Journal: Cell Death Differ
Title: Functional crosstalk between myeloid Foxo1-β-catenin axis and Hedgehog/Gli1 signaling in oxidative stress response.
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Publication
29925521 | J:293125
First Author: Yang B
Year: 2018
Journal: J Am Soc Nephrol
Title: Caspase-3 Is a Pivotal Regulator of Microvascular Rarefaction and Renal Fibrosis after Ischemia-Reperfusion Injury.
Volume: 29
Issue: 7
Pages: 1900-1916
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Publication
31745214 | J:357710
First Author: Wang T
Year: 2020
Journal: Cell Death Differ
Title: Necroptosis is dispensable for motor neuron degeneration in a mouse model of ALS.
Volume: 27
Issue: 5
Pages: 1728-1739
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Publication
31672932 | J:287900
 
First Author: Zhang B
Year: 2019
Journal: JCI Insight
Title: O-GlcNAc transferase suppresses necroptosis and liver fibrosis.
Volume: 4
Issue: 21
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Publication
26582950 | J:240016
First Author: Moriwaki K
Year: 2016
Journal: J Immunol
Title: The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages.
Volume: 196
Issue: 1
Pages: 407-15
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Publication
31653783 | J:292494
First Author: Huang M
Year: 2019
Journal: J Am Soc Nephrol
Title: Integrin-Linked Kinase Deficiency in Collecting Duct Principal Cell Promotes Necroptosis of Principal Cell and Contributes to Kidney Inflammation and Fibrosis.
Volume: 30
Issue: 11
Pages: 2073-2090
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Publication
35859177 | J:331943
First Author: Hubbard NW
Year: 2022
Journal: Nature
Title: ADAR1 mutation causes ZBP1-dependent immunopathology.
Volume: 607
Issue: 7920
Pages: 769-775
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Publication
30697165 | J:309747
 
First Author: Zhang X
Year: 2018
Journal: Front Physiol
Title: Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L-Arginine, L-Ornithine, and L-Histidine.
Volume: 9
Pages: 1922
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Publication
31164717 | J:282718
First Author: Jacobs SBR
Year: 2020
Journal: Cell Death Differ
Title: Siva plays a critical role in mouse embryonic development.
Volume: 27
Issue: 1
Pages: 297-309
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Publication
29078411 | J:257222
First Author: Wang H
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP.
Volume: 114
Issue: 45
Pages: 11944-11949
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Publication
38022500 | J:343321
 
First Author: Pefanis A
Year: 2023
Journal: Front Immunol
Title: Dynamics of necroptosis in kidney ischemia-reperfusion injury.
Volume: 14
Pages: 1251452
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Publication
34162724 | J:308019
     
First Author: Tu H
Year: 2021
Journal: J Immunol
Title: Linear Ubiquitination of RIPK1 on Lys 612 Regulates Systemic Inflammation via Preventing Cell Death.
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Publication
36191211 | J:353327
First Author: Rodriguez DA
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Caspase-8 and FADD prevent spontaneous ZBP1 expression and necroptosis.
Volume: 119
Issue: 41
Pages: e2207240119
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Publication
31076724 | J:279198
     
First Author: Yang D
Year: 2019
Journal: Cell Mol Immunol
Title: ZBP1 mediates interferon-induced necroptosis.
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Publication
31019191 | J:278887
First Author: Zhang C
Year: 2019
Journal: Cell Death Dis
Title: Inhibition of HtrA2 alleviated dextran sulfate sodium (DSS)-induced colitis by preventing necroptosis of intestinal epithelial cells.
Volume: 10
Issue: 5
Pages: 344
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Publication
31217278 | J:281281
First Author: Chen J
Year: 2019
Journal: J Biol Chem
Title: Interferon-γ induces the cell surface exposure of phosphatidylserine by activating the protein MLKL in the absence of caspase-8 activity.
Volume: 294
Issue: 32
Pages: 11994-12006
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