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Search results 701 to 774 out of 774 for Rxra

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Type Details Score
Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
29143738 | J:254390
   
First Author: Halstead AM
Year: 2017
Journal: Elife
Title: Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation.
Volume: 6
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GXD Expression
GXD Expression
Probe: MGI:1314968
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6188090
Age: embryonic day 12.5
Image: 5F
Note: Authors report co-localization of expression with Rxra only in walls of large veins.
Specimen Label: 5F
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1314968
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550121
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6188090
Age: embryonic day 13.5
Image: 5I
Note: Authors report co-localization of expression with Rxra only in walls of large veins.
Specimen Label: 5I
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:1314968
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6188090
Age: embryonic day 12.5
Image: 5E
Note: Authors report co-localization of expression with Rxra only in walls of large veins.
Specimen Label: 5E
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:1314968
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1720320
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6188090
Age: embryonic day 12.5
Image: 5G
Note: Authors report co-localization of expression with Rxra in cells not associated with vessels or sinusoidal cells.
Specimen Label: 5G
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:1314968
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1720320
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6188090
Age: embryonic day 12.5
Image: 5H
Note: Authors report co-localization of expression with Rxra in cells not associated with vessels or sinusoidal cells.
Specimen Label: 5H
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:1314968
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1720321
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6188090
Age: embryonic day 13.5
Image: 5J
Note: Authors report co-localization of expression with Rxra in cells not associated with vessels or sinusoidal cells.
Specimen Label: 5J
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:5428715
Assay Type: Immunohistochemistry
Annotation Date: 2012-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5428867
Age: embryonic day 12.5
Image: 7D
Note: Expression was seen in Rxra positive progenitors of the gut epithelium.
Specimen Label: 7D
Detected: true
Specimen Num: 22
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HT Experiment
E-MEXP-1711 | Transcription profiling of liver from wild type and RXR-alpha deficient matured and aged mcie
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE188991 | Metabolic maturation of neonatal hearts driven by gamma-linolenic acid in maternal milk [RNA-seq]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Tg(Myh6-Rxra)41Pcn | MGI:5906918
Name: transgene insertion 41, Pierre Chambon
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(Myh6-Rxra)41Pcn/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
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Publication
16239304 | J:189993
First Author: Tomaru T
Year: 2006
Journal: Endocrinology
Title: Isolation and characterization of a transcriptional cofactor and its novel isoform that bind the deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma.
Volume: 147
Issue: 1
Pages: 377-88
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Protein Domain
IPR031191 | HELZ2
Type: Family
Description: Helicase with zinc finger domain 2 (HELZ2) is a helicase that acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB and RXRA []. It interacts with THRAP3 (thyroid hormone receptor-associated protein3), a putative component of the Mediator complex that plays a role in adipocyte differentiation [].
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Genotype
Genotype
Symbol: Rxra/Rxra Tg(Myh6-Rxra)41Pcn/?
Background: involves: 129S2/SvPas
Zygosity: cn
Has Mutant Allele: true
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Publication
23525231 | -
First Author: Katano-Toki A
Year: 2013
Journal: Mol Endocrinol
Title: THRAP3 interacts with HELZ2 and plays a novel role in adipocyte differentiation.
Volume: 27
Issue: 5
Pages: 769-80
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Publication
39571575 | J:359877
First Author: Wang Y
Year: 2024
Journal: Immunity
Title: A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control.
Volume: 57
Issue: 12
Pages: 2737-2754.e12
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Publication
39532884 | J:358609
First Author: Li Y
Year: 2024
Journal: Nat Commun
Title: A noncoding variant confers pancreatic differentiation defect and contributes to diabetes susceptibility by recruiting RXRA.
Volume: 15
Issue: 1
Pages: 9771
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Publication
25873367 | J:317290
First Author: Giardina C
Year: 2015
Journal: Cancer Prev Res (Phila)
Title: Regulation of VDR Expression in Apc-Mutant Mice, Human Colon Cancers and Adenomas.
Volume: 8
Issue: 5
Pages: 387-99
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Publication
33835049 | J:333276
First Author: Suzuki S
Year: 2021
Journal: Reproduction
Title: Differential RA responsiveness among subsets of mouse late progenitor spermatogonia.
Volume: 161
Issue: 6
Pages: 645-655
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Publication
16488448 | J:107713
First Author: Ouyang Y
Year: 2006
Journal: Mutat Res
Title: Loss of Ubr2, an E3 ubiquitin ligase, leads to chromosome fragility and impaired homologous recombinational repair.
Volume: 596
Issue: 1-2
Pages: 64-75
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Publication
18793138 | -
First Author: Belgareh-Touzé N
Year: 2008
Journal: Biochem Soc Trans
Title: Versatile role of the yeast ubiquitin ligase Rsp5p in intracellular trafficking.
Volume: 36
Issue: Pt 5
Pages: 791-6
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Publication
18202552 | -
First Author: Loring GL
Year: 2008
Journal: Cell Cycle
Title: Yeast Chfr homologs retard cell cycle at G1 and G2/M via Ubc4 and Ubc13/Mms2-dependent ubiquitination.
Volume: 7
Issue: 1
Pages: 96-105
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Publication
14976165 | -
First Author: Morris JR
Year: 2004
Journal: Hum Mol Genet
Title: BRCA1 : BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair.
Volume: 13
Issue: 8
Pages: 807-17
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Protein Domain
IPR017335 | RNF8
Type: Family
Description: This entry represents E3 ubiquitin-protein ligase RNF8, which may be required for proper exit from mitosis after spindle checkpoint activation and may regulate cytokinesis. This enzyme promotes the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer [, ]. Substrates that are poly-ubiquitinated at 'Lys-63' are usually not targeted for degradation. RNF8 acts following DNA double-strand break (DSB) formation, and is recruited to the sites of damage by ATM-phosphorylated MDC1, where it promotes the formation of TP53BP1 and BRCA1 ionizing radiation-induced foci (IRIF) [, ]. It may play a role in the regulation of RXRA-mediated transcriptional activity, but is not involved in RXRA ubiquitination by UBE2E2.Ubiquitinylation is an ATP-dependent process that involves the action of at least three enzymes: a ubiquitin-activating enzyme (E1, ), a ubiquitin-conjugating enzyme (E2, ), and a ubiquitin ligase (E3, , ), which work sequentially in a cascade. There are many different E3 ligases, which are responsible for the type of ubiquitin chain formed, the specificity of the target protein, and the regulation of the ubiquitinylation process []. Ubiquitinylation is an important regulatory tool that controls the concentration of key signalling proteins, such as those involved in cell cycle control, as well as removing misfolded, damaged or mutant proteins that could be harmful to the cell. Several ubiquitin-like molecules have been discovered, such as Ufm1 (), SUMO1 (), NEDD8, Rad23 (), Elongin B and Parkin (), the latter being involved in Parkinson's disease [].
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Protein
Q7TT03
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: false
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Protein
Q922U3
Organism: Mus musculus/domesticus
Length: 717  
Fragment?: true
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Protein
Q69ZA7
Organism: Mus musculus/domesticus
Length: 1622  
Fragment?: true
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Publication
12646216 | -
First Author: Hatakeyama S
Year: 2003
Journal: Biochem Biophys Res Commun
Title: U-box proteins as a new family of ubiquitin ligases.
Volume: 302
Issue: 4
Pages: 635-45
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Publication
15564047 | -
First Author: Ross CA
Year: 2004
Journal: Trends Cell Biol
Title: The ubiquitin-proteasome pathway in Parkinson's disease and other neurodegenerative diseases.
Volume: 14
Issue: 12
Pages: 703-11
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Protein
A2AS05
Organism: Mus musculus/domesticus
Length: 2903  
Fragment?: false
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Protein
Q3TZD5
Organism: Mus musculus/domesticus
Length: 1754  
Fragment?: true
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Protein
E9QAM5
Organism: Mus musculus/domesticus
Length: 2947  
Fragment?: false
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Protein
A2AS03
Organism: Mus musculus/domesticus
Length: 2970  
Fragment?: false
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Protein
Q8VC56
Organism: Mus musculus/domesticus
Length: 488  
Fragment?: false
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Protein
Q6A027
Organism: Mus musculus/domesticus
Length: 749  
Fragment?: true
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Protein
E0CXC2
Organism: Mus musculus/domesticus
Length: 719  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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