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Search results 701 to 790 out of 790 for Ski

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Type Details Score
Protein
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 673  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 808  
Fragment?: true
Publication
First Author: Kim SS
Year: 2002
Journal: Structure
Title: Structure of the retinal determination protein Dachshund reveals a DNA binding motif.
Volume: 10
Issue: 6
Pages: 787-95
Publication  
First Author: Yang K
Year: 2022
Journal: J Clin Invest
Title: Cytoplasmic RNA quality control failure engages mTORC1-mediated autoinflammatory disease.
Volume: 132
Issue: 2
Publication  
First Author: Suzuki A
Year: 2018
Journal: Mech Dev
Title: Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis.
Volume: 150
Pages: 21-27
Protein
Organism: Mus musculus/domesticus
Length: 795  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 744  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 44  
Fragment?: true
Protein Domain
Type: Homologous_superfamily
Description: The SAND domain (named after Sp100, AIRE-1, NucP41/75, DEAF-1) is a conserved ~80 residue region found in a number of nuclear proteins, many of which function in chromatin-dependent transcriptional control. These include proteins linked to various human diseases, such as the Sp100 (Speckled protein 100kDa), NUDR (Nuclear DEAF-1 related), GMEB (Glucocorticoid Modulatory Element Binding) proteins and AIRE-1 (Autoimmune regulator 1) proteins.Proteins containing the SAND domain have a modular structure; the SAND domain can be associated with a number of other modules, including the bromodomain, the PHD finger and the MYND finger. Because no SAND domain has been found in yeast, it is thought that the SAND domain could be restricted to animal phyla. Many SAND domain-containing proteins, including NUDR, DEAF-1 (Deformed epidermal autoregulatory factor-1) and GMEB, have been shown to bind DNA sequences specifically. The SAND domain has been proposed to mediate the DNA binding activity of these proteins [, ]. Structurally, the SAND domain consists of a novel alpha/beta fold, which has a core of three short helices packed against a barrel-like β-sheet; it is structurally similar to the SH3-like fold.Other proteins display domains that are structurally similar to the SAND domain. One such example is the SMAD4-binding domain of the oncoprotein Ski, which is stabilised by a bound zinc atom, and resembles a SAND domain, in which the corresponding I loop is responsible for DNA binding. Ski is able to disrupt the formation of a functional complex between the Co- and R-SMADs, leading to the repression of TGF-beta, Activin and BMP responses, resulting in the repression of TGF-signalling [].
Publication
First Author: Gee S
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Cloning of mDEAH9, a putative RNA helicase and mammalian homologue of Saccharomyces cerevisiae splicing factor Prp43.
Volume: 94
Issue: 22
Pages: 11803-7
Publication
First Author: Lee CG
Year: 1998
Journal: Genomics
Title: Molecular analysis of the cDNA and genomic DNA encoding mouse RNA helicase A.
Volume: 47
Issue: 3
Pages: 365-71
Publication
First Author: Morello F
Year: 2020
Journal: Cell Rep
Title: Molecular Fingerprint and Developmental Regulation of the Tegmental GABAergic and Glutamatergic Neurons Derived from the Anterior Hindbrain.
Volume: 33
Issue: 2
Pages: 108268
Protein
Organism: Mus musculus/domesticus
Length: 1244  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1244  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 884  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1244  
Fragment?: false
Publication
First Author: Borsani G
Year: 1999
Journal: Hum Mol Genet
Title: EYA4, a novel vertebrate gene related to Drosophila eyes absent.
Volume: 8
Issue: 1
Pages: 11-23
Publication
First Author: Li X
Year: 2003
Journal: Nature
Title: Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis.
Volume: 426
Issue: 6964
Pages: 247-54
Publication
First Author: Abdelhak S
Year: 1997
Journal: Nat Genet
Title: A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family.
Volume: 15
Issue: 2
Pages: 157-64
Publication
First Author: Cook PJ
Year: 2009
Journal: Nature
Title: Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions.
Volume: 458
Issue: 7238
Pages: 591-6
Publication  
First Author: Jemc J
Year: 2007
Journal: Annu Rev Biochem
Title: The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription.
Volume: 76
Pages: 513-38
Protein
Organism: Mus musculus/domesticus
Length: 1040  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 993  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 562  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 530  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 563  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 53  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 445  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 450  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 575  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 127  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 411  
Fragment?: true
Publication
First Author: Gibson TJ
Year: 1998
Journal: Trends Biochem Sci
Title: The APECED polyglandular autoimmune syndrome protein, AIRE-1, contains the SAND domain and is probably a transcription factor.
Volume: 23
Issue: 7
Pages: 242-4
Publication
First Author: Bottomley MJ
Year: 2001
Journal: Nat Struct Biol
Title: The SAND domain structure defines a novel DNA-binding fold in transcriptional regulation.
Volume: 8
Issue: 7
Pages: 626-33
Publication
First Author: Tootle TL
Year: 2003
Journal: Nature
Title: The transcription factor Eyes absent is a protein tyrosine phosphatase.
Volume: 426
Issue: 6964
Pages: 299-302
Protein
Organism: Mus musculus/domesticus
Length: 510  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 566  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 482  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 445  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 526  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 464  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 464  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 418  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 507  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 283  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 494  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 482  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 419  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 397  
Fragment?: false
Publication
First Author: Akagi K
Year: 2008
Journal: Genome Res
Title: Extensive variation between inbred mouse strains due to endogenous L1 retrotransposition.
Volume: 18
Issue: 6
Pages: 869-80
Publication
First Author: Yang Z
Year: 2000
Journal: Exp Clin Immunogenet
Title: Organizations and gene duplications of the human and mouse MHC complement gene clusters.
Volume: 17
Issue: 1
Pages: 1-17
Protein
Organism: Mus musculus/domesticus
Length: 317  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 317  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 591  
Fragment?: false
Publication
First Author: Shimizu H
Year: 2013
Journal: PLoS One
Title: The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.
Volume: 8
Issue: 10
Pages: e75754
Publication
First Author: Bailey PJ
Year: 2006
Journal: Exp Cell Res
Title: A global genomic transcriptional code associated with CNS-expressed genes.
Volume: 312
Issue: 16
Pages: 3108-19
Protein
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 302  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 552  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 493  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 551  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 534  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 552  
Fragment?: false
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Allcock RJ
Year: 2000
Journal: Immunol Today
Title: The mouse as a model for the effects of MHC genes on human disease.
Volume: 21
Issue: 7
Pages: 328-32
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication      
First Author: Overbeek PA
Year: 2011
Journal: MGI Direct Data Submission
Title: Direct Data Submission for Overbeek Lentiviral Transgenic Lines
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication      
First Author: Mager J
Year: 2019
Journal: MGI Direct Data Submission
Title: A Catalog of Early Lethal KOMP Phenotypes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 4
Pages: 167-80
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping