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Search results 701 to 800 out of 998 for Snca

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Type Details Score
Publication
29272304 | J:254622
First Author: Zhou W
Year: 2017
Journal: PLoS One
Title: Running wheel exercise reduces α-synuclein aggregation and improves motor and cognitive function in a transgenic mouse model of Parkinson's disease.
Volume: 12
Issue: 12
Pages: e0190160
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Publication
26317866 | J:243017
First Author: Chen X
Year: 2015
Journal: PLoS One
Title: Longitudinal Metabolomics Profiling of Parkinson's Disease-Related α-Synuclein A53T Transgenic Mice.
Volume: 10
Issue: 8
Pages: e0136612
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Publication
20457918 | J:160542
First Author: Tong Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice.
Volume: 107
Issue: 21
Pages: 9879-84
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Publication
30150626 | J:266239
First Author: Bae EJ
Year: 2018
Journal: Nat Commun
Title: LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation.
Volume: 9
Issue: 1
Pages: 3465
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Publication
24388731 | J:211953
First Author: Ginns EI
Year: 2014
Journal: Mol Genet Metab
Title: Neuroinflammation and α-synuclein accumulation in response to glucocerebrosidase deficiency are accompanied by synaptic dysfunction.
Volume: 111
Issue: 2
Pages: 152-62
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Publication
29246723 | J:268285
 
First Author: Schapansky J
Year: 2018
Journal: Neurobiol Dis
Title: Familial knockin mutation of LRRK2 causes lysosomal dysfunction and accumulation of endogenous insoluble α-synuclein in neurons.
Volume: 111
Pages: 26-35
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Publication
24412932 | J:210101
First Author: Mahul-Mellier AL
Year: 2014
Journal: Hum Mol Genet
Title: c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease.
Volume: 23
Issue: 11
Pages: 2858-79
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Publication
26643113 | J:338235
 
First Author: Helferich AM
Year: 2015
Journal: Mol Neurodegener
Title: α-synuclein interacts with SOD1 and promotes its oligomerization.
Volume: 10
Pages: 66
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Publication
22232689 | J:179915
First Author: Ranson A
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Homeostatic plasticity mechanisms are required for juvenile, but not adult, ocular dominance plasticity.
Volume: 109
Issue: 4
Pages: 1311-6
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Publication
21045828 | J:220941
 
First Author: Fujita M
Year: 2010
Journal: Nat Commun
Title: A β-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brain.
Volume: 1
Pages: 110
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Publication
26170293 | J:225977
First Author: McGlinchey RP
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Cysteine cathepsins are essential in lysosomal degradation of α-synuclein.
Volume: 112
Issue: 30
Pages: 9322-7
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Publication
31041657 | J:295776
First Author: Bistaffa E
Year: 2019
Journal: Mol Neurobiol
Title: Prion Efficiently Replicates in α-Synuclein Knockout Mice.
Volume: 56
Issue: 11
Pages: 7448-7457
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Publication
33972291 | J:320992
 
First Author: Stoyka LE
Year: 2021
Journal: eNeuro
Title: Templated α-Synuclein Inclusion Formation Is Independent of Endogenous Tau.
Volume: 8
Issue: 3
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Publication
32560668 | J:319327
First Author: Takaichi Y
Year: 2020
Journal: Acta Neuropathol Commun
Title: Phosphorylation and oligomerization of α-synuclein associated with GSK-3β activation in the rTg4510 mouse model of tauopathy.
Volume: 8
Issue: 1
Pages: 86
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Publication
27378698 | J:237861
First Author: Magalhaes J
Year: 2016
Journal: Hum Mol Genet
Title: Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson disease.
Volume: 25
Issue: 16
Pages: 3432-3445
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Publication
11312297 | J:68925
First Author: Simon HH
Year: 2001
Journal: J Neurosci
Title: Fate of midbrain dopaminergic neurons controlled by the engrailed genes.
Volume: 21
Issue: 9
Pages: 3126-34
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Publication
24691202 | J:215043
First Author: Cochain C
Year: 2014
Journal: PLoS One
Title: Programmed cell death-1 deficiency exacerbates T cell activation and atherogenesis despite expansion of regulatory T cells in atherosclerosis-prone mice.
Volume: 9
Issue: 4
Pages: e93280
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Publication
25825709 | J:220456
First Author: Wang S
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation.
Volume: 112
Issue: 15
Pages: E1926-35
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Publication
29863470 | J:264191
   
First Author: Rousseaux MW
Year: 2018
Journal: Elife
Title: Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau.
Volume: 7
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Publication
21593311 | J:173360
First Author: Anwar S
Year: 2011
Journal: J Neurosci
Title: Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family.
Volume: 31
Issue: 20
Pages: 7264-74
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Publication
23382946 | J:195914
First Author: Paine SM
Year: 2013
Journal: PLoS One
Title: Pale body-like inclusion formation and neurodegeneration following depletion of 26S proteasomes in mouse brain neurones are independent of α-synuclein.
Volume: 8
Issue: 1
Pages: e54711
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Publication
26676570 | J:329750
First Author: Fan Z
Year: 2016
Journal: Mol Neurobiol
Title: MicroRNA-7 Enhances Subventricular Zone Neurogenesis by Inhibiting NLRP3/Caspase-1 Axis in Adult Neural Stem Cells.
Volume: 53
Issue: 10
Pages: 7057-7069
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Publication
34736896 | J:346429
First Author: Ninkina N
Year: 2021
Journal: J Biol Chem
Title: β-synuclein potentiates synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death in the absence of other synucleins.
Volume: 297
Issue: 6
Pages: 101375
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Publication
27779468 | J:238738
   
First Author: Rousseaux MW
Year: 2016
Journal: Elife
Title: TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau.
Volume: 5
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Publication
20858756 | J:172332
First Author: Geng X
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: α-Synuclein binds the K(ATP) channel at insulin-secretory granules and inhibits insulin secretion.
Volume: 300
Issue: 2
Pages: E276-86
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Publication
25051958 | J:216227
First Author: Luo J
Year: 2014
Journal: Hum Mol Genet
Title: A calcineurin- and NFAT-dependent pathway is involved in α-synuclein-induced degeneration of midbrain dopaminergic neurons.
Volume: 23
Issue: 24
Pages: 6567-74
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Publication
28246328 | J:241369
First Author: Dunn AR
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease.
Volume: 114
Issue: 11
Pages: E2253-E2262
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Publication
33000527 | J:329509
First Author: Jiao L
Year: 2020
Journal: FASEB J
Title: Tau knockout exacerbates degeneration of parvalbumin-positive neurons in substantia nigra pars reticulata in Parkinson's disease-related α-synuclein A53T mice.
Volume: 34
Issue: 9
Pages: 12239-12254
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Publication
23011138 | J:339900
 
First Author: Rhinn H
Year: 2012
Journal: Nat Commun
Title: Alternative α-synuclein transcript usage as a convergent mechanism in Parkinson's disease pathology.
Volume: 3
Pages: 1084
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Publication
38713200 | J:359062
   
First Author: Stavsky A
Year: 2024
Journal: Elife
Title: Synapsin E-domain is essential for α-synuclein function.
Volume: 12
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Publication
25316793 | J:216676
First Author: Rothaug M
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: LIMP-2 expression is critical for β-glucocerebrosidase activity and α-synuclein clearance.
Volume: 111
Issue: 43
Pages: 15573-8
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Publication
24865427 | J:213197
First Author: Liu G
Year: 2014
Journal: J Clin Invest
Title: Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation.
Volume: 124
Issue: 7
Pages: 3032-46
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Publication
35021075 | J:320659
First Author: Alam MM
Year: 2022
Journal: Cell Rep
Title: Alpha synuclein, the culprit in Parkinson disease, is required for normal immune function.
Volume: 38
Issue: 2
Pages: 110090
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Publication
29899409 | J:306595
First Author: Chen J
Year: 2018
Journal: Cell Death Dis
Title: Phosphorylation of Parkin at serine 131 by p38 MAPK promotes mitochondrial dysfunction and neuronal death in mutant A53T α-synuclein model of Parkinson's disease.
Volume: 9
Issue: 6
Pages: 700
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Publication
29966750 | J:270236
 
First Author: Miki Y
Year: 2018
Journal: Neurosci Lett
Title: Autophagy mediators (FOXO1, SESN3 and TSC2) in Lewy body disease and aging.
Volume: 684
Pages: 35-41
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Publication
31167929 | J:275659
 
First Author: Gerez JA
Year: 2019
Journal: Sci Transl Med
Title: A cullin-RING ubiquitin ligase targets exogenous α-synuclein and inhibits Lewy body-like pathology.
Volume: 11
Issue: 495
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Publication
38615036 | J:348472
First Author: Guo C
Year: 2024
Journal: Sci Rep
Title: Plasminogen degrades α-synuclein, Tau and TDP-43 and decreases dopaminergic neurodegeneration in mouse models of Parkinson's disease.
Volume: 14
Issue: 1
Pages: 8581
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Publication
25394490 | J:258908
First Author: Credle JJ
Year: 2015
Journal: Cell Death Differ
Title: GSK-3β dysregulation contributes to parkinson's-like pathophysiology with associated region-specific phosphorylation and accumulation of tau and α-synuclein.
Volume: 22
Issue: 5
Pages: 838-51
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Publication
35599331 | J:325698
First Author: Lu J
Year: 2022
Journal: J Neuroinflammation
Title: A breakdown in microglial metabolic reprogramming causes internalization dysfunction of α-synuclein in a mouse model of Parkinson's disease.
Volume: 19
Issue: 1
Pages: 113
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Publication
16096643 | J:104448
First Author: Sato S
Year: 2006
Journal: EMBO J
Title: 14-3-3eta is a novel regulator of parkin ubiquitin ligase.
Volume: 25
Issue: 1
Pages: 211-21
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Publication
20638384 | J:163468
First Author: Adamczyk A
Year: 2010
Journal: FEBS Lett
Title: Alpha-synuclein induced cell death in mouse hippocampal (HT22) cells is mediated by nitric oxide-dependent activation of caspase-3.
Volume: 584
Issue: 15
Pages: 3504-8
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Publication
17296554 | J:136786
First Author: Ihara M
Year: 2007
Journal: Neuron
Title: Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity.
Volume: 53
Issue: 4
Pages: 519-33
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Publication
19744960 | J:153971
First Author: Giovannone B
Year: 2009
Journal: Hum Mol Genet
Title: GIGYF2 gene disruption in mice results in neurodegeneration and altered insulin-like growth factor signaling.
Volume: 18
Issue: 23
Pages: 4629-39
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Publication
17592014 | J:122792
First Author: Jacobs FM
Year: 2007
Journal: Development
Title: Retinoic acid counteracts developmental defects in the substantia nigra caused by Pitx3 deficiency.
Volume: 134
Issue: 14
Pages: 2673-84
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Publication
31036561 | J:276471
First Author: Panicker N
Year: 2019
Journal: J Exp Med
Title: Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia.
Volume: 216
Issue: 6
Pages: 1411-1430
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Publication
16037097 | J:102679
First Author: von Bohlen und Halbach O
Year: 2005
Journal: FASEB J
Title: Haploinsufficiency for trkB and trkC receptors induces cell loss and accumulation of alpha-synuclein in the substantia nigra.
Volume: 19
Issue: 12
Pages: 1740-2
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Publication
18790059 | J:142519
First Author: Westerlund M
Year: 2008
Journal: Mol Cell Neurosci
Title: Lrrk2 and alpha-synuclein are co-regulated in rodent striatum.
Volume: 39
Issue: 4
Pages: 586-91
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Publication
18665422 | J:141972
First Author: Akil O
Year: 2008
Journal: J Assoc Res Otolaryngol
Title: Localization of synucleins in the mammalian cochlea.
Volume: 9
Issue: 4
Pages: 452-63
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Publication
23077667 | J:192205
First Author: Lambertsen KL
Year: 2012
Journal: PLoS One
Title: Genetic KCa3.1-deficiency produces locomotor hyperactivity and alterations in cerebral monoamine levels.
Volume: 7
Issue: 10
Pages: e47744
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Publication
26203154 | J:225806
First Author: Tang FL
Year: 2015
Journal: J Neurosci
Title: VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease.
Volume: 35
Issue: 29
Pages: 10613-28
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Publication
34555357 | J:334103
First Author: Scheiblich H
Year: 2021
Journal: Cell
Title: Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes.
Volume: 184
Issue: 20
Pages: 5089-5106.e21
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Publication
24046356 | J:202836
First Author: Baptista MA
Year: 2013
Journal: Dis Model Mech
Title: A strategy for the generation, characterization and distribution of animal models by The Michael J. Fox Foundation for Parkinson's Research.
Volume: 6
Issue: 6
Pages: 1316-24
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Publication
- | J:188992
     
First Author: The Netherlands Cancer Institute
Year: 2012
Journal: MGI Direct Data Submission
Title: Direct data submission by The Netherlands Cancer Institute
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Publication
34462307 | J:311902
First Author: Komuro Y
Year: 2021
Journal: J Neurosci
Title: The Role of Galanin in Cerebellar Granule Cell Migration in the Early Postnatal Mouse during Normal Development and after Injury.
Volume: 41
Issue: 42
Pages: 8725-8741
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Publication
38648899 | J:348105
First Author: Chen H
Year: 2024
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Pre-eclamptic foetal programming predisposes offspring to hepatic steatosis via DNA methylation.
Volume: 1870
Issue: 5
Pages: 167189
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Publication
21423666 | J:171698
First Author: Pramparo T
Year: 2011
Journal: PLoS Genet
Title: Global developmental gene expression and pathway analysis of normal brain development and mouse models of human neuronal migration defects.
Volume: 7
Issue: 3
Pages: e1001331
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Publication
27864010 | J:239613
 
First Author: Zhang J
Year: 2017
Journal: Gene
Title: Differentially expressed genes in the testicular tissues of adenylyl cyclase 3 knockout mice.
Volume: 602
Pages: 33-42
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Publication
21151134 | J:169031
First Author: Sharma M
Year: 2011
Journal: Nat Cell Biol
Title: CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity.
Volume: 13
Issue: 1
Pages: 30-9
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Publication
28396396 | J:242134
First Author: Zhao Z
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Formation of neurodegenerative aggresome and death-inducing signaling complex in maternal diabetes-induced neural tube defects.
Volume: 114
Issue: 17
Pages: 4489-4494
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Publication
14973278 | J:88592
First Author: Smidt MP
Year: 2004
Journal: Development
Title: Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx3.
Volume: 131
Issue: 5
Pages: 1145-55
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Publication
27407143 | J:235155
First Author: Doucet-Beaupré H
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons.
Volume: 113
Issue: 30
Pages: E4387-96
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Publication
17444492 | J:136998
First Author: Trimarchi JM
Year: 2007
Journal: J Comp Neurol
Title: Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling.
Volume: 502
Issue: 6
Pages: 1047-65
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Publication
38912572 | J:352993
 
First Author: Krishnamurthy A
Year: 2024
Journal: Development
Title: Engrailed transcription factors direct excitatory cerebellar neuron diversity and survival.
Volume: 151
Issue: 14
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Publication
19409883 | J:150768
First Author: Okado H
Year: 2009
Journal: Dev Biol
Title: The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex.
Volume: 331
Issue: 2
Pages: 140-51
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Publication
32868762 | J:295412
First Author: Kim DW
Year: 2020
Journal: Nat Commun
Title: The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development.
Volume: 11
Issue: 1
Pages: 4360
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Publication
35906071 | J:333924
First Author: Wang S
Year: 2022
Journal: J Neurosci
Title: Functional Cooperation of α-Synuclein and Tau Is Essential for Proper Corticogenesis.
Volume: 42
Issue: 37
Pages: 7031-7046
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Publication
22748019 | J:185964
 
First Author: Sgadò P
Year: 2012
Journal: Neural Dev
Title: The atypical homeoprotein Pbx1a participates in the axonal pathfinding of mesencephalic dopaminergic neurons.
Volume: 7
Pages: 24
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Publication
31505254 | J:295435
 
First Author: Yli-Karjanmaa M
Year: 2019
Journal: Brain Behav Immun
Title: TNF deficiency causes alterations in the spatial organization of neurogenic zones and alters the number of microglia and neurons in the cerebral cortex.
Volume: 82
Pages: 279-297
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Publication
31315048 | J:294282
First Author: Li L
Year: 2019
Journal: Cell Rep
Title: The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling.
Volume: 28
Issue: 3
Pages: 698-711.e5
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Publication
31850343 | J:309996
 
First Author: Dumas S
Year: 2019
Journal: Front Cell Dev Biol
Title: Developmental Co-expression of Vglut2 and Nurr1 in a Mes-Di-Encephalic Continuum Preceeds Dopamine and Glutamate Neuron Specification.
Volume: 7
Pages: 307
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Publication
26758845 | J:228865
First Author: Law C
Year: 2016
Journal: J Neurosci
Title: Normal Molecular Specification and Neurodegenerative Disease-Like Death of Spinal Neurons Lacking the SNARE-Associated Synaptic Protein Munc18-1.
Volume: 36
Issue: 2
Pages: 561-76
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
19554387 | J:156036
First Author: Schilling K
Year: 2009
Journal: Cerebellum
Title: The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex.
Volume: 8
Issue: 4
Pages: 477-89
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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