Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Publication |
First Author: |
Sarantos MR |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Transmigration of neutrophils across inflamed endothelium is signaled through LFA-1 and Src family kinase. |
Volume: |
181 |
Issue: |
12 |
Pages: |
8660-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Evangelista V |
Year: |
2007 |
Journal: |
Blood |
Title: |
Src family kinases mediate neutrophil adhesion to adherent platelets. |
Volume: |
109 |
Issue: |
6 |
Pages: |
2461-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim HJ |
Year: |
2009 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo. |
Volume: |
106 |
Issue: |
7 |
Pages: |
2325-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee JH |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
The Src family kinase Fgr is critical for activation of mast cells and IgE-mediated anaphylaxis in mice. |
Volume: |
187 |
Issue: |
4 |
Pages: |
1807-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Borneo J |
Year: |
2007 |
Journal: |
Exp Hematol |
Title: |
Src family kinase-mediated negative regulation of hematopoietic stem cell mobilization involves both intrinsic and microenvironmental factors. |
Volume: |
35 |
Issue: |
7 |
Pages: |
1026-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rovedo M |
Year: |
2008 |
Journal: |
J Virol |
Title: |
Epstein-Barr virus latent membrane protein 2A preferentially signals through the Src family kinase Lyn. |
Volume: |
82 |
Issue: |
17 |
Pages: |
8520-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pereira S |
Year: |
2001 |
Journal: |
J Immunol |
Title: |
Resting murine neutrophils express functional alpha 4 integrins that signal through Src family kinases. |
Volume: |
166 |
Issue: |
6 |
Pages: |
4115-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Orschell CM |
Year: |
2008 |
Journal: |
Exp Hematol |
Title: |
Deficiency of Src family kinases compromises the repopulating ability of hematopoietic stem cells. |
Volume: |
36 |
Issue: |
5 |
Pages: |
655-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thomas SM |
Year: |
1997 |
Journal: |
Annu Rev Cell Dev Biol |
Title: |
Cellular functions regulated by Src family kinases. |
Volume: |
13 |
|
Pages: |
513-609 |
|
•
•
•
•
•
|
Publication |
First Author: |
Canobbio I |
Year: |
2015 |
Journal: |
Biochem J |
Title: |
The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets. |
Volume: |
469 |
Issue: |
2 |
Pages: |
199-210 |
|
•
•
•
•
•
|
Publication |
First Author: |
Prakash O |
Year: |
2005 |
Journal: |
Blood |
Title: |
Activation of Src kinase Lyn by the Kaposi sarcoma-associated herpesvirus K1 protein: implications for lymphomagenesis. |
Volume: |
105 |
Issue: |
10 |
Pages: |
3987-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boudot C |
Year: |
2003 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Involvement of the Src kinase Lyn in phospholipase C-gamma 2 phosphorylation and phosphatidylinositol 3-kinase activation in Epo signalling. |
Volume: |
300 |
Issue: |
2 |
Pages: |
437-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fumagalli L |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
The Src family kinases Hck and Fgr regulate neutrophil responses to N-formyl-methionyl-leucyl-phenylalanine. |
Volume: |
178 |
Issue: |
6 |
Pages: |
3874-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rawlings DJ |
Year: |
1996 |
Journal: |
Science |
Title: |
Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases. |
Volume: |
271 |
Issue: |
5250 |
Pages: |
822-5 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Wetzel DM |
Year: |
2016 |
Journal: |
J Cell Sci |
Title: |
The Src kinases Hck, Fgr and Lyn activate Arg to facilitate IgG-mediated phagocytosis and Leishmania infection. |
Volume: |
129 |
Issue: |
16 |
Pages: |
3130-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Paul R |
Year: |
2008 |
Journal: |
J Leukoc Biol |
Title: |
Myeloid Src kinases regulate phagocytosis and oxidative burst in pneumococcal meningitis by activating NADPH oxidase. |
Volume: |
84 |
Issue: |
4 |
Pages: |
1141-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kojima T |
Year: |
2001 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Genomic organization of the Shc-related phosphotyrosine adapters and characterization of the full-length Sck/ShcB: specific association of p68-Sck/ShcB with pp135. |
Volume: |
284 |
Issue: |
4 |
Pages: |
1039-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Curtis DJ |
Year: |
2000 |
Journal: |
Exp Hematol |
Title: |
Adaptor protein SKAP55R is associated with myeloid differentiation and growth arrest. |
Volume: |
28 |
Issue: |
11 |
Pages: |
1250-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ménasché G |
Year: |
2007 |
Journal: |
Mol Cell Biol |
Title: |
RIAM links the ADAP/SKAP-55 signaling module to Rap1, facilitating T-cell-receptor-mediated integrin activation. |
Volume: |
27 |
Issue: |
11 |
Pages: |
4070-81 |
|
•
•
•
•
•
|
Allele |
Name: |
Rous sarcoma oncogene; targeted mutation 1.1, Goro Kato |
Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
Allele |
Name: |
Rous sarcoma oncogene; targeted mutation 2.1, Goro Kato |
Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Li S |
Year: |
2007 |
Journal: |
Int J Biochem Cell Biol |
Title: |
Src kinase signaling in leukaemia. |
Volume: |
39 |
Issue: |
7-8 |
Pages: |
1483-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Swanson KD |
Year: |
2008 |
Journal: |
Mol Cell |
Title: |
The Skap-hom dimerization and PH domains comprise a 3'-phosphoinositide-gated molecular switch. |
Volume: |
32 |
Issue: |
4 |
Pages: |
564-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu W |
Year: |
2012 |
Journal: |
Acta Crystallogr Sect F Struct Biol Cryst Commun |
Title: |
Lysozyme contamination facilitates crystallization of a heterotrimeric cortactin-Arg-lysozyme complex. |
Volume: |
68 |
Issue: |
Pt 2 |
Pages: |
154-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vines CM |
Year: |
2001 |
Journal: |
Immunity |
Title: |
Inhibition of beta 2 integrin receptor and Syk kinase signaling in monocytes by the Src family kinase Fgr. |
Volume: |
15 |
Issue: |
4 |
Pages: |
507-19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Giagulli C |
Year: |
2006 |
Journal: |
J Immunol |
Title: |
The Src family kinases Hck and Fgr are dispensable for inside-out, chemoattractant-induced signaling regulating beta 2 integrin affinity and valency in neutrophils, but are required for beta 2 integrin-mediated outside-in signaling involved in sustained adhesion. |
Volume: |
177 |
Issue: |
1 |
Pages: |
604-11 |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Mlih M |
Year: |
2015 |
Journal: |
J Biol Chem |
Title: |
The Src homology and collagen A (ShcA) adaptor protein is required for the spatial organization of the costamere/Z-disk network during heart development. |
Volume: |
290 |
Issue: |
4 |
Pages: |
2419-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ma YC |
Year: |
2002 |
Journal: |
Cell Mol Life Sci |
Title: |
Novel regulation and function of Src tyrosine kinase. |
Volume: |
59 |
Issue: |
3 |
Pages: |
456-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Imamura T |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport. |
Volume: |
276 |
Issue: |
47 |
Pages: |
43663-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miglarese MR |
Year: |
1994 |
Journal: |
Oncogene |
Title: |
The protein tyrosine kinase substrate cortactin is differentially expressed in murine B lymphoid tumors. |
Volume: |
9 |
Issue: |
7 |
Pages: |
1989-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Williams MR |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
An essential role for cortactin in the modulation of the potassium channel Kv1.2. |
Volume: |
104 |
Issue: |
44 |
Pages: |
17412-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ishino M |
Year: |
1995 |
Journal: |
Oncogene |
Title: |
Molecular cloning of a cDNA encoding a phosphoprotein, Efs, which contains a Src homology 3 domain and associates with Fyn. |
Volume: |
11 |
Issue: |
11 |
Pages: |
2331-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gustafsson K |
Year: |
2013 |
Journal: |
Exp Cell Res |
Title: |
The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity. |
Volume: |
319 |
Issue: |
12 |
Pages: |
1852-64 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
546
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
509
 |
Fragment?: |
false |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
901 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
901 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
511 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
511 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
24 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
24 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
74 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
74 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
19 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
19 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
737 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
737 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
64 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
64 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
341 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
341 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
340 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
340 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
253 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
253 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
890 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
890 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
340 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
340 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
311 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
311 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
332 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
332 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
333 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
333 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
279 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
279 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
264 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
264 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
152 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
152 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
146 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
146 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
126 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
126 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
142 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
142 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
10 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
10 |
|
•
•
•
•
•
|