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Search results 701 to 800 out of 1344 for T2

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0.043s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Genotype
Genotype
Symbol: Bcl3/Bcl3
Background: involves: 129S4/SvJae
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Card11/Card11<+>
Background: involves: C57BL/6
Zygosity: ht
Has Mutant Allele: true
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ncRNA Gene
MGI:3652329 | Gm11690
Type: lncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_CAROLIEiJ_G0004822 | -
Type: ncRNA_gene
Organism: Mus caroli
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ncRNA Gene
MGP_129S1SvImJ_G0005315 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_AJ_G0005298 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_AKRJ_G0005277 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_BALBcJ_G0005280 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_C3HHeJ_G0005229 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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lncRNA Gene
MGI_C57BL6J_3652329 | -
Type: lncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_C57BL6NJ_G0005432 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_CASTEiJ_G0005176 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_CBAJ_G0005218 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_DBA2J_G0005236 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_FVBNJ_G0005261 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_LPJ_G0005317 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_NODShiLtJ_G0005243 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_NZOHlLtJ_G0005436 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_PWKPhJ_G0005125 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_WSBEiJ_G0005224 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_SPRETEiJ_G0005046 | -
Type: ncRNA_gene
Organism: Mus spretus
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Publication
34435359 | J:333855
First Author: Wang F
Year: 2022
Journal: Immunology
Title: LncRNA00492 is required for marginal zone B-cell development.
Volume: 165
Issue: 1
Pages: 88-98
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Protein Coding Gene
MGI:1913802 | Sppl2a
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q9D505
Organism: Mus musculus/domesticus
Length: 106  
Fragment?: false
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Protein
Q9CVC3
Organism: Mus musculus/domesticus
Length: 73  
Fragment?: true
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Protein Domain
IPR036430 | RNase_T2-like_sf
Type: Homologous_superfamily
Description: Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far. This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases) [, , , , ]. Plant T2 RNases are expressed during leaf senescence in order to scavenge phosphate from ribonucleotides. They are also expressed in response to wounding or pathogen invasion. S-RNases are thought to prevent self-fertilization by acting as selective cytotoxins of "self"pollen. Generally, RNases have two distinct binding sites: the primary site (B1 site) and the subsite (B2 site), for nucleotides located at the 5'- and 3'- terminal ends of the sissile bond, respectively.The fungal ribonucleases T2 from Aspergillus oryzae, M from Aspergillus saitoi and Rh from Rhizopus niveus are structurally and functionally related 30 Kd glycoproteins []that cleave the 3'-5' internucleotide linkage of RNA via a nucleotide 2',3'-cyclic phosphate intermediate (). Two histidines residues have been shown [, ]to be involved in the catalytic mechanism of RNase T2 and Rh. These residues and the region around them are highly conserved ina number of other RNAses that have been found to be evolutionary related to these fungal enzymes.The structure of ribonuclease T2 is composed of an alpha+beta fold.
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Publication
27705781 | J:240500
First Author: López-Doménech G
Year: 2016
Journal: Cell Rep
Title: Loss of Dendritic Complexity Precedes Neurodegeneration in a Mouse Model with Disrupted Mitochondrial Distribution in Mature Dendrites.
Volume: 17
Issue: 2
Pages: 317-327
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Publication
12077353 | J:82103
First Author: Goodson HV
Year: 2002
Journal: J Cell Sci
Title: Molecular evolution of the actin family.
Volume: 115
Issue: Pt 13
Pages: 2619-22
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Protein Domain
IPR039378 | RNase_T2_prok
Type: Family
Description: Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far. This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases) [, , , , ]. Plant T2 RNases are expressed during leaf senescence in order to scavenge phosphate from ribonucleotides. They are also expressed in response to wounding or pathogen invasion. S-RNases are thought to prevent self-fertilization by acting as selective cytotoxins of "self"pollen. Generally, RNases have two distinct binding sites: the primary site (B1 site) and the subsite (B2 site), for nucleotides located at the 5'- and 3'- terminal ends of the sissile bond, respectively.This entry includes the prokaryotic RNase T2 family members.
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Protein Domain
IPR033697 | Ribonuclease_T2_eukaryotic
Type: Family
Description: Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far. This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases) [, , , , ]. Plant T2 RNases are expressed during leaf senescence in order to scavenge phosphate from ribonucleotides. They are also expressed in response to wounding or pathogen invasion. S-RNases are thought to prevent self-fertilization by acting as selective cytotoxins of "self"pollen. Generally, RNases have two distinct binding sites: the primary site (B1 site) and the subsite (B2 site), for nucleotides located at the 5'- and 3'- terminal ends of the sissile bond, respectively.This entry includes the eukaryotic RNase T2 family members.
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Strain
MGI:5544437 | STOCK Tg(Tnnt2-cre)5Blh/JiaoJ
Attribute String: mutant stock, transgenic
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Strain
MGI:5616438 | B6.129S6(Cg)-Ntrk2<tm3.1(cre/ERT2)Ddg>/J
Attribute String: targeted mutation, mutant strain, congenic
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Allele
Rorb<tm1.1(cre/ERT2)Ddg> | MGI:5828138
Name: RAR-related orphan receptor beta; targeted mutation 1.1, David D Ginty
Allele Type: Targeted
Attribute String: Inducible, Recombinase
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Allele
Tg(SFTPC-SFTPA1*)T2Jflo | MGI:7365194
Name: transgene insertion T2, Joanna Floros
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:7562437 | STOCK Tacr1<tm1.1(cre/ERT2)Ddg>/J
Attribute String: mutant stock, targeted mutation
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Strain
MGI:7562435 | STOCK Gpr83<tm1.1(cre/ERT2)Ddg>/J
Attribute String: mutant stock, targeted mutation
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Allele
Rr343500<em1Zkoz> | MGI:7720870
Name: regulatory region 343500; endonuclease-mediated mutation 1, Zbynek Kozmik
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Genotype
Genotype
Symbol: Ntrk2/Ntrk2
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bicra/Bicra Tg(Tnnt2-cre)5Blh/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Protein
A0A338P711
Organism: Mus musculus/domesticus
Length: 163  
Fragment?: true
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Protein
A0A338P7E3
Organism: Mus musculus/domesticus
Length: 163  
Fragment?: false
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Protein
C0HKG5
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
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Protein
C0HKG6
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
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Protein
Q5FWA0
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
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Protein Domain
IPR001568 | RNase_T2-like
Type: Family
Description: Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far. This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases(S-RNases) [, , , , ]. Plant T2 RNases are expressed during leaf senescence in order to scavenge phosphate from ribonucleotides. They are also expressed in response to wounding or pathogen invasion. S-RNases are thought to prevent self-fertilization by acting as selective cytotoxins of "self"pollen. Generally, RNases have two distinct binding sites: the primary site (B1 site) and the subsite (B2 site), for nucleotides located at the 5'- and 3'- terminal ends of the sissile bond, respectively.The fungal ribonucleases T2 from Aspergillus oryzae, M from Aspergillus saitoi and Rh from Rhizopus niveus are structurally and functionally related 30 Kd glycoproteins []that cleave the 3'-5' internucleotide linkage of RNA via a nucleotide 2',3'-cyclic phosphate intermediate (). Two histidines residues have been shown [, ]to be involved in the catalytic mechanism of RNase T2 and Rh. These residues and the region around them are highly conserved in a number of other RNAses that have been found to be evolutionary related to these fungal enzymes.
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Allele
Nfkb2<xdr> | MGI:2667230
 
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100; xander
Allele Type: Chemically induced (ENU)
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Allele
Igh-J<tm1.1Lave> | MGI:4421672
 
Name: immunoglobulin heavy chain, joining region; targeted mutation 1.1, Laurent Verkoczy
Allele Type: Targeted
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Transgene
MGI:4454684 | Tg(H2-K<b>-IL21)5Wjl
Type: transgene
Organism: mouse, laboratory
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Allele
Gimap1<tm1.1Gwb> | MGI:4459837
Name: GTPase, IMAP family member 1; targeted mutation 1.1, Geoffrey W Butcher
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Atp11c<m1Btlr> | MGI:4843273
 
Name: ATPase, class VI, type 11C; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
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Allele
Kdelr1<m1Btlr> | MGI:4843278
Name: KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Null/knockout
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Allele
Nfkbia<tm1.1Smiy> | MGI:4941306
 
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; targeted mutation 1.1, Shigeki Miyamoto
Allele Type: Targeted
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Allele
Grb2<tm1Lnit> | MGI:4949889
Name: growth factor receptor bound protein 2; targeted mutation 1, Lars Nitschke
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Igh<tm1.1Twin> | MGI:5140396
Name: immunoglobulin heavy chain complex; targeted mutation 1.1, Thomas H Winkler
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Cd79a<tm1.1Rsky> | MGI:5301876
 
Name: CD79A antigen (immunoglobulin-associated alpha); targeted mutation 1.1, Klaus Rajewsky
Allele Type: Targeted
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Allele
Akap13<tm1Segj> | MGI:5308769
Name: A kinase anchor protein 13; targeted mutation 1, James H Segars
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Sppl2a<chompB> | MGI:5484577
Name: signal peptide peptidase like 2A; chompB
Allele Type: Chemically induced (ENU)
Attribute String: Hypomorph
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Allele
Sppl2a<tm1Basc> | MGI:5491887
Name: signal peptide peptidase like 2A; targeted mutation 1, Bernd Schroder
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Ell2<tm1.1Cmil> | MGI:5790670
Name: elongation factor for RNA polymerase II 2; targeted mutation 1.1, Christine Milcarek
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Map3k14<tm1.2Gne> | MGI:5903085
Name: mitogen-activated protein kinase kinase kinase 14; targeted mutation 1.2, Genentech
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Niban3<tm1Jyw> | MGI:6388736
Name: niban apoptosis regulator 3; targeted mutation 1, Ji-Yang Wang
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Card11<em1Welu> | MGI:6491988
Name: caspase recruitment domain family, member 11; endonuclease-mediated mutation 1, Wei Lu
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Genotype
Genotype
Symbol: Nfkb2/Nfkb2
Background: C57BL/6JSfdAnu-Nfkb2/Anu
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Plcg2/Plcg2
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igh-J/Igh-J<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(H2-K-IL21)5Wjl/?
Background: involves: 129
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sh3kbp1/Sh3kbp1 Cd79a/Cd79a<+>
Background: involves: BALB/c * C57BL/6 * NZB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Tnfsf13b)1Fma/Tg(Tnfsf13b)1Fma
Background: involves: C57BL/6 * DBA/2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Cd19/Cd19
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Akap13/Akap13<+>
Background: involves: 129
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd22/Cd22
Background: involves: 129S4/SvJae
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sppl2a/Sppl2a
Background: B6.129P2-Sppl2a
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sppl2a/Sppl2a
Background: involves: C57BL/6JAnu
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Card11/Card11
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
16109376 | J:101015
First Author: Jang MK
Year: 2005
Journal: Mol Cell
Title: The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription.
Volume: 19
Issue: 4
Pages: 523-34
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Publication
17213798 | J:117306
 
First Author: Xiao W
Year: 2006
Journal: Mol Vis
Title: Gene expression profiling in embryonic mouse lenses.
Volume: 12
Pages: 1692-8
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Publication
1633875 | -
First Author: Kurihara H
Year: 1992
Journal: FEBS Lett
Title: Crystal and molecular structure of RNase Rh, a new class of microbial ribonuclease from Rhizopus niveus.
Volume: 306
Issue: 2-3
Pages: 189-92
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Publication
2229029 | -
First Author: Watanabe H
Year: 1990
Journal: J Biochem
Title: Primary structure of a base non-specific and adenylic acid preferential ribonuclease from Aspergillus saitoi.
Volume: 108
Issue: 2
Pages: 303-10
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Publication
11029414 | -
First Author: Yu SL
Year: 2000
Journal: J Bacteriol
Title: Characterization of the distal tail fiber locus and determination of the receptor for phage AR1, which specifically infects Escherichia coli O157:H7.
Volume: 182
Issue: 21
Pages: 5962-8
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Protein Domain
IPR007932 | Receptor-recog_Gp38
Type: Family
Description: T-even bacteriophages recognise their cellular receptors with the free ends of their six long tail fibres. The Gp38 protein from bacteriophage T2 and related phages is located at the tip of the tail fibre, where it recognises the host receptor []. OmpC has been identified as the host receptor, and sequence variations appear to be an important determinant of host specificity [].Note this family is not related, either in sequence similairty or function, to the Gp38 protein from bacteriophage T4.
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Publication
17585069 | J:140299
First Author: Song L
Year: 2007
Journal: Circ Res
Title: Myocardial smad4 is essential for cardiogenesis in mouse embryos.
Volume: 101
Issue: 3
Pages: 277-85
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Publication
29765066 | J:278055
First Author: Manalo A
Year: 2018
Journal: Sci Rep
Title: Loss of CENP-F Results in Dilated Cardiomyopathy with Severe Disruption of Cardiac Myocyte Architecture.
Volume: 8
Issue: 1
Pages: 7546
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Publication
22563055 | J:185133
First Author: Dees E
Year: 2012
Journal: Dis Model Mech
Title: Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathy.
Volume: 5
Issue: 4
Pages: 468-80
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Strain
MGI:5828146 | STOCK Rorb<tm1.1(cre/ERT2)Ddg>/J
Attribute String: targeted mutation, mutant stock
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Allele
Tg(CDX2-cre/ERT2)741Erf | MGI:7433054
Name: transgene insertion 741, Eric Fearon
Allele Type: Transgenic
Attribute String: Recombinase
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Genotype
Genotype
Symbol: Hand2/Hand2<+> Tg(Tnnt2-cre)5Blh/?
Background: involves: 129S1/Sv * C57BL/6J * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lims1/Lims1 Tg(Tnnt2-cre)5Blh/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pdlim5/Pdlim5 Tg(Tnnt2-cre)5Blh/?
Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cenpf/Cenpf Tg(Tnnt2-cre)5Blh/?
Background: involves: C57BL/6 * DBA/2 * ICR
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Vegfa/Vegfa Tg(Tnnt2-cre)5Blh/?
Background: involves: 129/Sv * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Tnnt2-cre)5Blh/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nexn/Nexn Tg(Tnnt2-cre)5Blh/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Jag1/Jag1 Tg(Tnnt2-cre)5Blh/?
Background: involves: 129 * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ogt/Ogt Tg(Tnnt2-cre)5Blh/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Protein Coding Gene
MGI:1915387 | Kdelr1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:3686743 | Niban3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1889583 | Sh3kbp1
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Plcg2<tm1Jni> | MGI:2386100
Name: phospholipase C, gamma 2; targeted mutation 1, James N Ihle
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Hax1<tm1.1Gach> | MGI:5056144
Name: HCLS1 associated X-1; targeted mutation 1.1, Gernot Achatz
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Gt(ROSA)26Sor<tm2(CAG-Notch2*)Uzs> | MGI:5301613
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Ursula Zimber-Strobl
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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