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Search results 701 to 735 out of 735 for Tardbp

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Type Details Score
Publication
First Author: Swarup V
Year: 2012
Journal: J Neurosci
Title: Abnormal regenerative responses and impaired axonal outgrowth after nerve crush in TDP-43 transgenic mouse models of amyotrophic lateral sclerosis.
Volume: 32
Issue: 50
Pages: 18186-95
Strain
Attribute String: mutant strain, endonuclease-mediated mutation, coisogenic
Strain
Attribute String: endonuclease-mediated mutation, mutant stock
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: congenic, mutant strain, targeted mutation
Genotype
Symbol: Tardbp/Tardbp
Background: C57BL/6J-Tardbp
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tardbp/Tardbp Tg(Stra8-icre)1Reb/?
Background: involves: C57BL/6 * FVB/NJ * SJL
Zygosity: cn
Has Mutant Allele: true
HT Experiment
Series Id: GSE54418
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication  
First Author: Ma S
Year: 2021
Journal: J Exp Med
Title: The RNA m6A reader YTHDF2 controls NK cell antitumor and antiviral immunity.
Volume: 218
Issue: 8
Publication
First Author: Horiuchi M
Year: 2024
Journal: Acta Neuropathol Commun
Title: ALS-linked mutant TDP-43 in oligodendrocytes induces oligodendrocyte damage and exacerbates motor dysfunction in mice.
Volume: 12
Issue: 1
Pages: 184
Publication
First Author: Stallings NR
Year: 2010
Journal: Neurobiol Dis
Title: Progressive motor weakness in transgenic mice expressing human TDP-43.
Volume: 40
Issue: 2
Pages: 404-14
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Kevin Talbot
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter
Genotype
Symbol: Tardbp/Tardbp Tg(CAG-cre/Esr1*)5Amc/?
Background: involves: 129 * C57BL/6 * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tardbp/Tardbp
Background: involves: 129 * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tardbp/Tardbp<+>
Background: involves: 129 * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tardbp/Tardbp<+> Tg(CAG-cre/Esr1*)5Amc/?
Background: involves: 129 * C57BL/6 * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
Publication  
First Author: Picher-Martel V
Year: 2023
Journal: Int J Mol Sci
Title: Distinct Plasma Immune Profile in ALS Implicates sTNFR-II in pAMPK/Leptin Homeostasis.
Volume: 24
Issue: 6
Publication  
First Author: Audet JN
Year: 2012
Journal: Neuroscience
Title: Methylene blue administration fails to confer neuroprotection in two amyotrophic lateral sclerosis mouse models.
Volume: 209
Pages: 136-43
Publication  
First Author: Zhang F
Year: 2015
Journal: Front Aging Neurosci
Title: Miro1 deficiency in amyotrophic lateral sclerosis.
Volume: 7
Pages: 100
Publication  
First Author: Chaytow H
Year: 2022
Journal: EBioMedicine
Title: Targeting phosphoglycerate kinase 1 with terazosin improves motor neuron phenotypes in multiple models of amyotrophic lateral sclerosis.
Volume: 83
Pages: 104202
Publication
First Author: Swarup V
Year: 2011
Journal: Brain
Title: Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments.
Volume: 134
Issue: Pt 9
Pages: 2610-26
Strain
Attribute String: targeted mutation, mutant stock
Strain
Attribute String: mutant stock, targeted mutation
Publication  
First Author: Feneberg E
Year: 2020
Journal: Neurobiol Dis
Title: An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress.
Volume: 144
Pages: 105050
Publication
First Author: Vieira de Sá R
Year: 2024
Journal: Nat Commun
Title: ATAXIN-2 intermediate-length polyglutamine expansions elicit ALS-associated metabolic and immune phenotypes.
Volume: 15
Issue: 1
Pages: 7484
Publication
First Author: Stover CM
Year: 2004
Journal: Mamm Genome
Title: Organization of the MASP2 locus and its expression profile in mouse and rat.
Volume: 15
Issue: 11
Pages: 887-900
Publication
First Author: Chaya T
Year: 2022
Journal: J Biol Chem
Title: Multiple knockout mouse and embryonic stem cell models reveal the role of miR-124a in neuronal maturation.
Volume: 298
Issue: 9
Pages: 102293
Publication  
First Author: Sieverding K
Year: 2021
Journal: Exp Neurol
Title: Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43G298S transgenic mice.
Volume: 335
Pages: 113496
Publication
First Author: Xu YF
Year: 2010
Journal: J Neurosci
Title: Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice.
Volume: 30
Issue: 32
Pages: 10851-9
Publication
First Author: Ke YD
Year: 2015
Journal: Acta Neuropathol
Title: Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.
Volume: 130
Issue: 5
Pages: 661-78
Publication
First Author: Cho KW
Year: 2023
Journal: Circulation
Title: Polycomb Group Protein CBX7 Represses Cardiomyocyte Proliferation Through Modulation of the TARDBP/RBM38 Axis.
Volume: 147
Issue: 24
Pages: 1823-1842
Publication
First Author: Heck MV
Year: 2014
Journal: Neurogenetics
Title: Dysregulated expression of lipid storage and membrane dynamics factors in Tia1 knockout mouse nervous tissue.
Volume: 15
Issue: 2
Pages: 135-44
Publication  
First Author: Gordon D
Year: 2018
Journal: Neurobiol Dis
Title: Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction.
Volume: 121
Pages: 148-162
Publication  
First Author: Loeffler T
Year: 2020
Journal: Front Neurosci
Title: Neurofilament-Light Chain as Biomarker of Neurodegenerative and Rare Diseases With High Translational Value.
Volume: 14
Pages: 579
Publication      
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)