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Search results 701 to 736 out of 736 for Tet2

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Type Details Score
Publication
42202530 | J:390187
 
First Author: Seo W
Year: 2026
Journal: Biochem Biophys Res Commun
Title: Satb1 enforces CD4(+) effector T cell lineage stability by repressing Foxp3 via DNA methylation.
Volume: 827
Pages: 154026
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Publication
26601783 | J:231190
First Author: Kiladjian JJ
Year: 2016
Journal: Leukemia
Title: Interferon-alpha for the therapy of myeloproliferative neoplasms: targeting the malignant clone.
Volume: 30
Issue: 4
Pages: 776-81
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Publication
28449087 | J:247059
First Author: Zhang P
Year: 2017
Journal: Nucleic Acids Res
Title: Methyl-CpG binding domain protein 1 regulates localization and activity of Tet1 in a CXXC3 domain-dependent manner.
Volume: 45
Issue: 12
Pages: 7118-7136
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Publication
29769264 | J:266032
First Author: Ng SY
Year: 2018
Journal: Blood
Title: RhoA G17V is sufficient to induce autoimmunity and promotes T-cell lymphomagenesis in mice.
Volume: 132
Issue: 9
Pages: 935-947
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Publication
32938585 | J:299188
First Author: Li S
Year: 2020
Journal: Cancer Discov
Title: Somatic Mutations Drive Specific, but Reversible, Epigenetic Heterogeneity States in AML.
Volume: 10
Issue: 12
Pages: 1934-1949
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Publication
34183665 | J:356124
First Author: Lu Y
Year: 2021
Journal: Cell Discov
Title: Spatial transcriptome profiling by MERFISH reveals fetal liver hematopoietic stem cell niche architecture.
Volume: 7
Issue: 1
Pages: 47
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Publication
39131272 | J:361559
     
First Author: Gioulbasani M
Year: 2024
Journal: bioRxiv
Title: TET proteins regulate Drosha expression and impact microRNAs in iNKT cells.
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Publication
16606617 | J:114350
First Author: Cho YS
Year: 2006
Journal: J Biol Chem
Title: Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor.
Volume: 281
Issue: 26
Pages: 17588-98
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Protein
G3UXC9
Organism: Mus musculus/domesticus
Length: 104  
Fragment?: true
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Protein
Q3UQU6
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: true
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Protein Domain
IPR007759 | Asxl_HARE-HTH
Type: Domain
Description: This domain, known as the HARE-HTH domain, adopts the winged helix-turn-helix fold and is predicted to bind DNA. It can be found at the N terminus of the ASXL protein. It can also be found in several other eukaryotic chromatin proteins (such as HB1 in plants), diverse restriction endonucleases and DNA glycosylases, the RNA polymerase delta subunit of Gram-positive bacteria and certain bacterial proteins that combine features of the RNA polymerase alpha-subunit and sigma factors []. The genetic interaction of the HARE-HTH containing ASXL with the methyl cytosine hydroxylating Tet2 protein is suggestive of a role for the domain in discriminating sequences with DNA modifications such as hmC []. Bacterial versions include fusions to diverse restriction endonucleases, and a DNA glycosylase where it may play a similar role in detecting modified DNA. Certain bacterial version of the HARE-HTH domain show fusions to the helix-hairpin-helix domain of the RNA polymerase alpha subunit and the HTH domains found in regions 3 and 4 of the sigma factors []. These versions are predicted to function as a novel inhibitor of the binding of RNA polymerase to transcription start sites, similar to the Bacillus delta protein [, ].This domain consists of four ��-helices (helices I-II-III-IV) and an antiparallel ��-sheet composed of three short ��-strands at the top of a "twisted tripod"formed by helices II, III, and IV [].The Asx-like (Asxl) proteins includes Asxl1-3. They are putative Polycomb group (PcG) proteins, which act by forming multiprotein complexes that are required to maintain the transcriptionally repressive state of homeotic genes throughout development. Asxl1 is involved in transcriptional regulation mediated by ligand-bound retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG) [].The delta protein is a dispensable subunit of Bacillus subtilis RNA polymerase (RNAP) that has major effects on the biochemical properties of the purified enzyme. In the presence of delta, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling []. The delta protein, contains two distinct regions, an N-terminal domain and a glutamate and aspartate residue-rich C-terminal region []. It participates in both the initiation and recycling phases of transcription.
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Publication
41356199 | J:378225
First Author: Ding Y
Year: 2026
Journal: Theranostics
Title: Targeting CPS1 attenuates lung cancer metastasis by regulating EMT through an epigenetic mechanism.
Volume: 16
Issue: 4
Pages: 1740-1761
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Publication
38048324 | J:360014
First Author: Feng J
Year: 2023
Journal: PLoS Pathog
Title: NSUN2-mediated m5C modification of HBV RNA positively regulates HBV replication.
Volume: 19
Issue: 12
Pages: e1011808
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Publication
29615405 | J:264226
First Author: Inaba T
Year: 2018
Journal: Blood
Title: The enigma of monosomy 7.
Volume: 131
Issue: 26
Pages: 2891-2898
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Publication
33705482 | J:304554
First Author: Ono R
Year: 2021
Journal: PLoS One
Title: Tet1 is not required for myeloid leukemogenesis by MLL-ENL in novel mouse models.
Volume: 16
Issue: 3
Pages: e0248425
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Publication
10336502 | -
First Author: L?pez de Saro FJ
Year: 1999
Journal: J Biol Chem
Title: Expression, abundance, and RNA polymerase binding properties of the delta factor of Bacillus subtilis.
Volume: 274
Issue: 22
Pages: 15953-8
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Publication
7545758 | -
First Author: L?pez de Saro FJ
Year: 1995
Journal: J Mol Biol
Title: Structural analysis of the Bacillus subtilis delta factor: a protein polyanion which displaces RNA from RNA polymerase.
Volume: 252
Issue: 2
Pages: 189-202
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Publication
20310067 | -
First Author: Mot?ckov? V
Year: 2010
Journal: Proteins
Title: Solution structure of the N-terminal domain of Bacillus subtilis delta subunit of RNA polymerase and its classification based on structural homologs.
Volume: 78
Issue: 7
Pages: 1807-10
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Publication
31649729 | J:311748
 
First Author: Malloy MA
Year: 2019
Journal: Front Genet
Title: Perinatal Bisphenol A Exposure and Reprogramming of Imprinted Gene Expression in the Adult Mouse Brain.
Volume: 10
Pages: 951
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Publication
37564681 | J:371812
 
First Author: Zhang H
Year: 2023
Journal: Burns Trauma
Title: p53 promotes the expansion of regulatory T cells via DNMT3a- and TET2- mediated Foxp3 expression in sepsis.
Volume: 11
Pages: tkad021
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Publication
35502657 | J:334535
First Author: Chakraborty R
Year: 2022
Journal: Circulation
Title: Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.
Volume: 145
Issue: 23
Pages: 1720-1737
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Protein
P59598
Organism: Mus musculus/domesticus
Length: 1514  
Fragment?: false
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Protein
Q8BZ32
Organism: Mus musculus/domesticus
Length: 1370  
Fragment?: false
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Protein
Q8C4A5
Organism: Mus musculus/domesticus
Length: 2259  
Fragment?: false
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Protein
A0A2I3BQW0
Organism: Mus musculus/domesticus
Length: 1513  
Fragment?: false
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Protein
A0A668KLS4
Organism: Mus musculus/domesticus
Length: 2260  
Fragment?: false
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Protein
B2RUG8
Organism: Mus musculus/domesticus
Length: 1418  
Fragment?: false
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Protein
D6REV1
Organism: Mus musculus/domesticus
Length: 1370  
Fragment?: false
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Protein
F6WV21
Organism: Mus musculus/domesticus
Length: 1370  
Fragment?: false
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Protein
Q24JP2
Organism: Mus musculus/domesticus
Length: 1514  
Fragment?: false
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Protein
Q8BJR0
Organism: Mus musculus/domesticus
Length: 495  
Fragment?: true
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Protein
D3Z112
Organism: Mus musculus/domesticus
Length: 597  
Fragment?: false
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Protein
D6RI62
Organism: Mus musculus/domesticus
Length: 403  
Fragment?: true
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Publication
22186017 | -
First Author: Aravind L
Year: 2012
Journal: Cell Cycle
Title: The HARE-HTH and associated domains: novel modules in the coordination of epigenetic DNA and protein modifications.
Volume: 11
Issue: 1
Pages: 119-31
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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