Type |
Details |
Score |
Publication |
First Author: |
Crespo MI |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
TLR7 triggering with polyuridylic acid promotes cross-presentation in CD8α+ conventional dendritic cells by enhancing antigen preservation and MHC class I antigen permanence on the dendritic cell surface. |
Volume: |
190 |
Issue: |
3 |
Pages: |
948-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thomalla M |
Year: |
2022 |
Journal: |
Int J Mol Sci |
Title: |
Toll-like Receptor 7 (TLR7) Is Expressed in Adipocytes and the Pharmacological TLR7 Agonist Imiquimod and Adipocyte-Derived Cell-Free Nucleic Acids (cfDNA) Regulate Adipocyte Function. |
Volume: |
23 |
Issue: |
15 |
|
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Merkenschlager J |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response. |
Volume: |
7 |
|
Pages: |
10281 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mavrommatis B |
Year: |
2016 |
Journal: |
J Immunol |
Title: |
Dichotomy between T Cell and B Cell Tolerance to Neonatal Retroviral Infection Permits T Cell Therapy. |
Volume: |
197 |
Issue: |
9 |
Pages: |
3628-3638 |
|
•
•
•
•
•
|
Publication |
First Author: |
Young GR |
Year: |
2012 |
Journal: |
PLoS Pathog |
Title: |
Negative selection by an endogenous retrovirus promotes a higher-avidity CD4+ T cell response to retroviral infection. |
Volume: |
8 |
Issue: |
5 |
Pages: |
e1002709 |
|
•
•
•
•
•
|
Publication |
First Author: |
Turcotte K |
Year: |
2005 |
Journal: |
J Exp Med |
Title: |
A mutation in the Icsbp1 gene causes susceptibility to infection and a chronic myeloid leukemia-like syndrome in BXH-2 mice. |
Volume: |
201 |
Issue: |
6 |
Pages: |
881-90 |
|
•
•
•
•
•
|
Other Genome Feature |
Type: |
endogenous_retroviral_sequence |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Kirchgessner TG |
Year: |
1989 |
Journal: |
J Biol Chem |
Title: |
Genetic and developmental regulation of the lipoprotein lipase gene: loci both distal and proximal to the lipoprotein lipase structural gene control enzyme expression. |
Volume: |
264 |
Issue: |
3 |
Pages: |
1473-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ihle JN |
Year: |
1978 |
Journal: |
Virology |
Title: |
Genetic analysis of the endogenous C3H murine leukemia virus genome: evidence for one locus unlinked to the endogenous murine leukemia virus genome of C57BL/6 mice. |
Volume: |
87 |
Issue: |
2 |
Pages: |
298-306 |
|
•
•
•
•
•
|
Publication |
First Author: |
McCubrey J |
Year: |
1982 |
Journal: |
J Exp Med |
Title: |
Allelism and linkage studies of murine leukemia virus activation genes in low leukemic strains of mice. |
Volume: |
155 |
Issue: |
4 |
Pages: |
1233-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
McCubrey J |
Year: |
1982 |
Journal: |
Cell |
Title: |
Genetic interactions in induction of endogenous murine leukemia virus from low leukemic mice. |
Volume: |
28 |
Issue: |
4 |
Pages: |
881-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
McCubrey J |
Year: |
1982 |
Journal: |
J Exp Med |
Title: |
Genetic interactions in the spontaneous production of endogenous murine leukemia virus in low leukemic mouse strains. |
Volume: |
156 |
Issue: |
2 |
Pages: |
337-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Horowitz JM |
Year: |
1982 |
Journal: |
J Virol |
Title: |
A locus that enhances the induction of endogenous ecotropic murine leukemia viruses is distinct from genome-length ecotropic proviruses. |
Volume: |
44 |
Issue: |
3 |
Pages: |
950-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mattano SS |
Year: |
1988 |
Journal: |
J Hered |
Title: |
Linkage of Nat and Es-1 in the mouse and development of strains congenic for N-acetyltransferase. |
Volume: |
79 |
Issue: |
6 |
Pages: |
430-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ceci JD |
Year: |
1990 |
Journal: |
Genomics |
Title: |
An interspecific backcross linkage map of mouse chromosome 8. |
Volume: |
6 |
Issue: |
1 |
Pages: |
72-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abonia JP |
Year: |
1993 |
Journal: |
Mamm Genome |
Title: |
Linkage of Agt and Actsk-1 to distal mouse chromosome 8 loci: a new conserved linkage. |
Volume: |
4 |
Issue: |
1 |
Pages: |
25-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Frankel WN |
Year: |
1994 |
Journal: |
Mamm Genome |
Title: |
Endogenous nonecotropic proviruses mapped with oligonucleotide probes from the long terminal repeat region. |
Volume: |
5 |
Issue: |
5 |
Pages: |
275-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Taylor BA |
Year: |
1999 |
Journal: |
Mamm Genome |
Title: |
Genotyping new BXD recombinant inbred mouse strains and comparison of BXD and consensus maps. |
Volume: |
10 |
Issue: |
4 |
Pages: |
335-48 |
|
•
•
•
•
•
|
Allele |
Name: |
toll-like receptor 7; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
toll-like receptor 7; targeted mutation 3, Shanghai Model Organisms Center |
Allele Type: |
Targeted |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
toll-like receptor 8; targeted mutation 3, Shanghai Model Organisms Center |
Allele Type: |
Targeted |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
Majer O |
Year: |
2019 |
Journal: |
Nature |
Title: |
Release from UNC93B1 reinforces the compartmentalized activation of select TLRs. |
Volume: |
575 |
Issue: |
7782 |
Pages: |
371-374 |
|
•
•
•
•
•
|
Publication |
First Author: |
Melchjorsen J |
Year: |
2005 |
Journal: |
J Virol |
Title: |
Activation of innate defense against a paramyxovirus is mediated by RIG-I and TLR7 and TLR8 in a cell-type-specific manner. |
Volume: |
79 |
Issue: |
20 |
Pages: |
12944-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kozak CA |
Year: |
1982 |
Journal: |
J Exp Med |
Title: |
Genetic mapping of ecotropic murine leukemia virus-inducing loci in six inbred strains. |
Volume: |
155 |
Issue: |
2 |
Pages: |
524-34 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
Jenkins NA |
Year: |
1982 |
Journal: |
J Virol |
Title: |
Ecotropic murine leukemia virus DNA content of normal and lymphomatous tissues of BXH-2 recombinant inbred mice. |
Volume: |
42 |
Issue: |
2 |
Pages: |
379-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Taylor BA |
Year: |
1989 |
Journal: |
Genomics |
Title: |
A mouse linkage testing stock possessing multiple copies of the endogenous ecotropic murine leukemia virus genome. |
Volume: |
5 |
Issue: |
2 |
Pages: |
221-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pilz A |
Year: |
1992 |
Journal: |
Mamm Genome |
Title: |
Mapping of the structural gene for S-adenosyl homocysteine hydrolase to mouse chromosome 2, and related sequences to chromosomes 8 and X. |
Volume: |
3 |
Issue: |
11 |
Pages: |
633-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Taylor BA |
Year: |
1993 |
Journal: |
Genomics |
Title: |
The MEV mouse linkage testing stock: mapping 30 novel proviral insertions and establishment of an improved stock. |
Volume: |
16 |
Issue: |
2 |
Pages: |
380-94 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
138
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
262
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Pohar J |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
The role of UNC93B1 protein in surface localization of TLR3 receptor and in cell priming to nucleic acid agonists. |
Volume: |
288 |
Issue: |
1 |
Pages: |
442-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sasai M |
Year: |
2011 |
Journal: |
Immunity |
Title: |
Love triangle between Unc93B1, TLR7, and TLR9 prevents fatal attraction. |
Volume: |
35 |
Issue: |
1 |
Pages: |
3-5 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
UNC93B1 is a multi-transmembrane domain-containing protein that plays an essential role in signalling by the nucleotide-sensing Toll-like receptors (TLRs), including TLR3, TLR7 and TLR9 [, ]. UNC93B1 delivers the nucleotide-sensing receptors TLR7 and TLR9 from the ER to endolysosomes []. It has been shown to recruit Syntenin-1 and dampen TLR7 signalling and prevent autoimmunity []. It also binds TLR9, and the release of TLR9 from UNC93B1 is required for TLR9 to function []. Mutations in the UNC93B1 gene that result in aberrant TLR trafficking can lead to autoimmune disease []. |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
Taylor BA |
Year: |
1985 |
Journal: |
J Virol |
Title: |
Chromosomal assignment of two endogenous ecotropic murine leukemia virus proviruses of the AKR/J mouse strain. |
Volume: |
56 |
Issue: |
1 |
Pages: |
172-5 |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 1, Silvia Bolland |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 6, Silvia Bolland |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Publication |
First Author: |
Botía-Sánchez M |
Year: |
2023 |
Journal: |
Front Immunol |
Title: |
Gut epithelial barrier dysfunction in lupus triggers a differential humoral response against gut commensals. |
Volume: |
14 |
|
Pages: |
1200769 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(Tlr7)1Boll/? |
Background: |
involves: C57BL/6 |
Zygosity: |
ot |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(Tlr7)6Boll/? |
Background: |
involves: C57BL/6 |
Zygosity: |
ot |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Jenkins NA |
Year: |
1982 |
Journal: |
J Virol |
Title: |
Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA sequences in chromosomes of Mus musculus. |
Volume: |
43 |
Issue: |
1 |
Pages: |
26-36 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
598
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
422
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
619
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen W |
Year: |
2008 |
Journal: |
Nat Struct Mol Biol |
Title: |
Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5. |
Volume: |
15 |
Issue: |
11 |
Pages: |
1213-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barnes BJ |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes. |
Volume: |
276 |
Issue: |
26 |
Pages: |
23382-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dideberg V |
Year: |
2007 |
Journal: |
Hum Mol Genet |
Title: |
An insertion-deletion polymorphism in the interferon regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases. |
Volume: |
16 |
Issue: |
24 |
Pages: |
3008-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sigurdsson S |
Year: |
2005 |
Journal: |
Am J Hum Genet |
Title: |
Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. |
Volume: |
76 |
Issue: |
3 |
Pages: |
528-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schoenemeyer A |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling. |
Volume: |
280 |
Issue: |
17 |
Pages: |
17005-12 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Interferon regulatory factor 5 (IRF5) is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection []. It is activated by TLR7 or TLR8 signalling []. Its structure has been revealed []. Variations of the IRF5 gene affects the susceptibility of a few diseases, such as inflammatory bowel disease 14 (IBD14) [], systemic lupus erythematosus 10 (SLEB10) []and Rheumatoid arthritis (RA). |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang JQ |
Year: |
2016 |
Journal: |
Blood |
Title: |
Inhibiting TLR9 and other UNC93B1-dependent TLRs paradoxically increases accumulation of MYD88L265P plasmablasts in vivo. |
Volume: |
128 |
Issue: |
12 |
Pages: |
1604-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Mouse Synonym Curation |
|
|
|
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
GSE9287 |
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
Publication |
First Author: |
Sisirak V |
Year: |
2014 |
Journal: |
J Exp Med |
Title: |
Genetic evidence for the role of plasmacytoid dendritic cells in systemic lupus erythematosus. |
Volume: |
211 |
Issue: |
10 |
Pages: |
1969-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tun-Kyi A |
Year: |
2011 |
Journal: |
Nat Immunol |
Title: |
Essential role for the prolyl isomerase Pin1 in Toll-like receptor signaling and type I interferon-mediated immunity. |
Volume: |
12 |
Issue: |
8 |
Pages: |
733-41 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
110
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
114
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
de la Cruz IP |
Year: |
2003 |
Journal: |
J Neurosci |
Title: |
sup-9, sup-10, and unc-93 may encode components of a two-pore K+ channel that coordinates muscle contraction in Caenorhabditis elegans. |
Volume: |
23 |
Issue: |
27 |
Pages: |
9133-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Perland E |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly Expressed in the Mouse Brain and Have a Potential Role in Energy Homeostasis. |
Volume: |
11 |
Issue: |
6 |
Pages: |
e0156912 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li S |
Year: |
2012 |
Journal: |
Medchemcomm |
Title: |
Comparative analysis of the biosynthetic systems for fungal bicyclo[2.2.2]diazaoctane indole alkaloids: the (+)/(-)-notoamide, paraherquamide and malbrancheamide pathways. |
Volume: |
3 |
Issue: |
8 |
Pages: |
987-996 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The proteins in this family are represented by UNC-93 from Caenorhabditis elegans and also includes protein unc-93 homologue A (UNC93A), protein unc-93 homologue B1 (UNC93B1), and UNC93-like protein MFSD11 (also called major facilitator superfamily domain-containing protein 11 or protein ET). UNC-93 colocalizes with SUP-10 and SUP-9 within muscle cells. UNC-93 acts as a regulatory subunit of a multi-subunit potassium channel complex that may function in coordinating muscle contraction in C. elegans []. UNC93B1 controls intracellular trafficking and transport of a subset of Toll-like receptors (TLRs), including TLR3, TLR7 and TLR9, from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signalling cascades []. MFSD11 is ubiquitously expressed in the periphery and the central nervous system of mice, where it is expressed in excitatory and inhibitory mouse brain neurons [].This group of proteins also includes Notoamide biosynthesis cluster protein O' from Aspergillus versicolor, which is involved in the biosynthesis of notoamide, a fungal indole alkaloid that belongs to a family of natural products containing a characteristic bicyclo[2.2.2]diazaoctane core []. |
|
•
•
•
•
•
|
Publication |
First Author: |
International Committee on Standardized Genetic Nomenclature for Mice |
Year: |
1993 |
|
Title: |
Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ishida H |
Year: |
2021 |
Journal: |
Nat Struct Mol Biol |
Title: |
Cryo-EM structures of Toll-like receptors in complex with UNC93B1. |
Volume: |
28 |
Issue: |
2 |
Pages: |
173-180 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ewald SE |
Year: |
2011 |
Journal: |
J Exp Med |
Title: |
Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase. |
Volume: |
208 |
Issue: |
4 |
Pages: |
643-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tilstra JS |
Year: |
2020 |
Journal: |
J Clin Invest |
Title: |
B cell-intrinsic TLR9 expression is protective in murine lupus. |
Volume: |
130 |
Issue: |
6 |
Pages: |
3172-3187 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nickerson KM |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
Exacerbated autoimmunity in the absence of TLR9 in MRL.Fas(lpr) mice depends on Ifnar1. |
Volume: |
190 |
Issue: |
8 |
Pages: |
3889-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouchess ML |
Year: |
2011 |
Journal: |
Immunity |
Title: |
Transmembrane mutations in Toll-like receptor 9 bypass the requirement for ectodomain proteolysis and induce fatal inflammation. |
Volume: |
35 |
Issue: |
5 |
Pages: |
721-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marshall-Clarke S |
Year: |
2006 |
Journal: |
Eur J Immunol |
Title: |
Influenza H2 haemagglutinin activates B cells via a MyD88-dependent pathway. |
Volume: |
36 |
Issue: |
1 |
Pages: |
95-106 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carlin LM |
Year: |
2013 |
Journal: |
Cell |
Title: |
Nr4a1-dependent Ly6C(low) monocytes monitor endothelial cells and orchestrate their disposal. |
Volume: |
153 |
Issue: |
2 |
Pages: |
362-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Singh TP |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation. |
Volume: |
7 |
|
Pages: |
13581 |
|
•
•
•
•
•
|
Publication |
First Author: |
Das A |
Year: |
2017 |
Journal: |
Immunity |
Title: |
Follicular Dendritic Cell Activation by TLR Ligands Promotes Autoreactive B Cell Responses. |
Volume: |
46 |
Issue: |
1 |
Pages: |
106-119 |
|
•
•
•
•
•
|
Publication |
First Author: |
Babcock RL |
Year: |
2022 |
Journal: |
Mol Immunol |
Title: |
Regulation and function of Id2 in plasmacytoid dendritic cells. |
Volume: |
148 |
|
Pages: |
6-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bonnardel J |
Year: |
2015 |
Journal: |
Cell Rep |
Title: |
Innate and adaptive immune functions of peyer's patch monocyte-derived cells. |
Volume: |
11 |
Issue: |
5 |
Pages: |
770-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barchet W |
Year: |
2005 |
Journal: |
Eur J Immunol |
Title: |
Dendritic cells respond to influenza virus through TLR7- and PKR-independent pathways. |
Volume: |
35 |
Issue: |
1 |
Pages: |
236-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hamilton JA |
Year: |
2017 |
Journal: |
J Immunol |
Title: |
Cutting Edge: Endogenous IFN-β Regulates Survival and Development of Transitional B Cells. |
Volume: |
199 |
Issue: |
8 |
Pages: |
2618-2623 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cheung MB |
Year: |
2021 |
Journal: |
J Immunol |
Title: |
Cutting Edge: Myosin 18A Is a Novel Checkpoint Regulator in B Cell Differentiation and Antibody-Mediated Immunity. |
Volume: |
206 |
Issue: |
11 |
Pages: |
2521-2526 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stebegg M |
Year: |
2020 |
Journal: |
Elife |
Title: |
Rejuvenating conventional dendritic cells and T follicular helper cell formation after vaccination. |
Volume: |
9 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ohto U |
Year: |
2018 |
Journal: |
Immunity |
Title: |
Toll-like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation. |
Volume: |
48 |
Issue: |
4 |
Pages: |
649-658.e4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pohar J |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Short single-stranded DNA degradation products augment the activation of Toll-like receptor 9. |
Volume: |
8 |
|
Pages: |
15363 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiao N |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
The Tpl2 mutation Sluggish impairs type I IFN production and increases susceptibility to group B streptococcal disease. |
Volume: |
183 |
Issue: |
12 |
Pages: |
7975-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Edgar LJ |
Year: |
2019 |
Journal: |
Cell Chem Biol |
Title: |
Targeted Delivery of Antigen to Activated CD169+ Macrophages Induces Bias for Expansion of CD8+ T Cells. |
Volume: |
26 |
Issue: |
1 |
Pages: |
131-136.e4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alrefai H |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells. |
Volume: |
7 |
|
Pages: |
11724 |
|
•
•
•
•
•
|
Publication |
First Author: |
Callahan JA |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
Cutting edge: ABIN-1 protects against psoriasis by restricting MyD88 signals in dendritic cells. |
Volume: |
191 |
Issue: |
2 |
Pages: |
535-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Honda K |
Year: |
2004 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling. |
Volume: |
101 |
Issue: |
43 |
Pages: |
15416-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barton GM |
Year: |
2006 |
Journal: |
Nat Immunol |
Title: |
Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA. |
Volume: |
7 |
Issue: |
1 |
Pages: |
49-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gorden KK |
Year: |
2006 |
Journal: |
J Immunol |
Title: |
Cutting edge: activation of murine TLR8 by a combination of imidazoquinoline immune response modifiers and polyT oligodeoxynucleotides. |
Volume: |
177 |
Issue: |
10 |
Pages: |
6584-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lopez-Pelaez M |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Protein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells. |
Volume: |
111 |
Issue: |
49 |
Pages: |
17432-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miyake K |
Year: |
2018 |
Journal: |
Int Immunol |
Title: |
Mechanisms controlling nucleic acid-sensing Toll-like receptors. |
Volume: |
30 |
Issue: |
2 |
Pages: |
43-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Soni C |
Year: |
2023 |
Journal: |
J Immunol |
Title: |
Cutting Edge: TLR2 Signaling in B Cells Promotes Autoreactivity to DNA via IL-6 Secretion. |
Volume: |
211 |
Issue: |
10 |
Pages: |
1475-1480 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li G |
Year: |
2020 |
Journal: |
iScience |
Title: |
Spermidine Suppresses Inflammatory DC Function by Activating the FOXO3 Pathway and Counteracts Autoimmunity. |
Volume: |
23 |
Issue: |
1 |
Pages: |
100807 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu L |
Year: |
2023 |
Journal: |
Cell Rep |
Title: |
SLC38A5 aggravates DC-mediated psoriasiform skin inflammation via potentiating lysosomal acidification. |
Volume: |
42 |
Issue: |
8 |
Pages: |
112910 |
|
•
•
•
•
•
|
Publication |
First Author: |
Medhavy A |
Year: |
2024 |
Journal: |
Nat Immunol |
Title: |
A TNIP1-driven systemic autoimmune disorder with elevated IgG4. |
Volume: |
25 |
Issue: |
9 |
Pages: |
1678-1691 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
449
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
458
 |
Fragment?: |
false |
|
•
•
•
•
•
|