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Search results 701 to 800 out of 809 for Trpm8

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Type Details Score
Publication
11804595 | J:137259
First Author: Hara Y
Year: 2002
Journal: Mol Cell
Title: LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death.
Volume: 9
Issue: 1
Pages: 163-73
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Publication
11385574 | J:354154
First Author: Nadler MJ
Year: 2001
Journal: Nature
Title: LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability.
Volume: 411
Issue: 6837
Pages: 590-5
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Publication
16436689 | J:122002
First Author: Damak S
Year: 2006
Journal: Chem Senses
Title: Trpm5 null mice respond to bitter, sweet, and umami compounds.
Volume: 31
Issue: 3
Pages: 253-64
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Protein
A0A1B0GT86
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: true
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Protein
A0A1W2P6F5
Organism: Mus musculus/domesticus
Length: 104  
Fragment?: true
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Protein
F6RUN7
Organism: Mus musculus/domesticus
Length: 190  
Fragment?: true
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Publication
12015988 | -
First Author: Launay P
Year: 2002
Journal: Cell
Title: TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization.
Volume: 109
Issue: 3
Pages: 397-407
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Publication
14576148 | J:87336
First Author: Voets T
Year: 2004
Journal: J Biol Chem
Title: TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption.
Volume: 279
Issue: 1
Pages: 19-25
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Publication
14634208 | -
First Author: Prawitt D
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+]i.
Volume: 100
Issue: 25
Pages: 15166-71
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Publication
15306801 | -
First Author: Voets T
Year: 2004
Journal: Nature
Title: The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels.
Volume: 430
Issue: 7001
Pages: 748-54
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Publication
18365021 | -
First Author: Clark K
Year: 2008
Journal: PLoS One
Title: Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7.
Volume: 3
Issue: 3
Pages: e1876
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Publication
21278253 | -
First Author: Lambert S
Year: 2011
Journal: J Biol Chem
Title: Transient receptor potential melastatin 1 (TRPM1) is an ion-conducting plasma membrane channel inhibited by zinc ions.
Volume: 286
Issue: 14
Pages: 12221-33
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Publication
29211723 | -
First Author: Winkler PA
Year: 2017
Journal: Nature
Title: Electron cryo-microscopy structure of a human TRPM4 channel.
Volume: 552
Issue: 7684
Pages: 200-204
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Protein Domain
IPR050927 | TRPM_cation_chan
Type: Family
Description: Members of the transient receptor potential cation channel subfamily M (TRPM) are voltage-independent, non-selective or monovalent-selective cation channels that mediate the influx of ions such as Ca(2+), Mg(2+), Na(+), and Zn(2+) [, , ]. They assemble as homotetramers or heterotetramers and are involved in a wide array of physiological processes [, ]. For instance, TRPM8 is a cold sensor activated by low temperatures and cooling agents like menthol [, ], while TRPM4 and TRPM5 are Ca(2+)-activated monovalent cation channels involved in membrane depolarization, with TRPM5 playing a key role in sweet, bitter, and umami taste transduction [, , ]. TRPM1 is essential for the depolarizing photoresponse of retinal ON bipolar cells []. TRPM2 is gated by intracellular ADP-ribose and oxidative stress, contributing to cell death susceptibility and immune responses [, ]. Uniquely, TRPM6 and TRPM7 are 'chanzymes' that possess an intrinsic C-terminal ��-kinase domain, playing crucial roles in organismal Mg(2+) homeostasis and embryonic development [, , ].
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Protein Domain
IPR031161 | Peptidase_M60_dom
Type: Domain
Description: The peptidase family M60 domain belongs to the Merops zincin superfamily of zinc-requiring metalloproteases (clan MA, subclan MA(E)). The peptidase family M60 domain contains the metal-binding consensus motif HExxH. The two histidine residues are ligands of the catalytic Zn(2) and the glutamic acid residue is involved in nucleophilic attack. An additional conserved glutamic acid is found approximately 20 residues from the first histidine within the metal-binding motif. The second conserved glutamic acid potentially acts as a third proteous Zn(2) ligand. The peptidase family M60 domain targets complex host glycoproteins, such as mucins [, , , , ].Some proteins known to contain a peptidase family M60 domain are listed below:Baculovirus viral enhancing factor (VEF), also known as Enhancin, a metalloprotease that enhances viral infection by degrading the peritrophic membrane (PM) of the insect midgut.Bacteria enhancin-like metalloproteases.Mammalian FAM115 family proteins (also known as TRPM8 channel-associated factor 1-3).
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Publication
42120494 | J:388027
First Author: Wang W
Year: 2026
Journal: EMBO Mol Med
Title: CCDC174 deficiency impaired human fertility by affecting the alternative splicing of maternal mRNAs.
Volume: 18
Issue: 6
Pages: 2436-2454
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Protein
A0A0U1RNU7
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Protein
A0A0U1RQ58
Organism: Mus musculus/domesticus
Length: 28  
Fragment?: true
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Protein
A0A494BA79
Organism: Mus musculus/domesticus
Length: 262  
Fragment?: false
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Protein
A0A494BAQ5
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: true
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Protein
D3Z539
Organism: Mus musculus/domesticus
Length: 234  
Fragment?: false
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Protein
Q8BJE6
Organism: Mus musculus/domesticus
Length: 361  
Fragment?: true
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Protein
Q8BKH4
Organism: Mus musculus/domesticus
Length: 369  
Fragment?: true
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Protein
Q8BKI1
Organism: Mus musculus/domesticus
Length: 369  
Fragment?: true
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Publication
25746468 | J:232755
First Author: Taylor-Clark TE
Year: 2015
Journal: PLoS One
Title: Thy1.2 YFP-16 transgenic mouse labels a subset of large-diameter sensory neurons that lack TRPV1 expression.
Volume: 10
Issue: 3
Pages: e0119538
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Publication
18671867 | J:273961
 
First Author: Cruz-Orengo L
Year: 2008
Journal: Mol Pain
Title: Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPA1.
Volume: 4
Pages: 30
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Publication
18667618 | J:139515
First Author: Fajardo O
Year: 2008
Journal: J Neurosci
Title: TRPA1 channels mediate cold temperature sensing in mammalian vagal sensory neurons: pharmacological and genetic evidence.
Volume: 28
Issue: 31
Pages: 7863-75
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Publication
42126073 | J:387464
   
First Author: Razlan AN
Year: 2026
Journal: Elife
Title: Characterisation of cold-selective lamina I spinal projection neurons in the mouse.
Volume: 14
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Publication
22025699 | J:180258
First Author: Zimmermann K
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Transient receptor potential cation channel, subfamily C, member 5 (TRPC5) is a cold-transducer in the peripheral nervous system.
Volume: 108
Issue: 44
Pages: 18114-9
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Publication
24133248 | J:202748
First Author: Patel R
Year: 2013
Journal: J Neurosci
Title: ?2?-1 gene deletion affects somatosensory neuron function and delays mechanical hypersensitivity in response to peripheral nerve damage.
Volume: 33
Issue: 42
Pages: 16412-26
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Publication
17588549 | J:123327
 
First Author: Sawada Y
Year: 2007
Journal: Brain Res
Title: Cold sensitivity of recombinant TRPA1 channels.
Volume: 1160
Pages: 39-46
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Publication
16899456 | J:117218
First Author: Smith PL
Year: 2006
Journal: J Biol Chem
Title: Bisandrographolide from Andrographis paniculata activates TRPV4 channels.
Volume: 281
Issue: 40
Pages: 29897-904
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Publication
20519530 | J:160809
First Author: Schmid A
Year: 2010
Journal: J Neurosci
Title: Grueneberg ganglion neurons are finely tuned cold sensors.
Volume: 30
Issue: 22
Pages: 7563-8
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Publication
11161216 | -
First Author: Runnels LW
Year: 2001
Journal: Science
Title: TRP-PLIK, a bifunctional protein with kinase and ion channel activities.
Volume: 291
Issue: 5506
Pages: 1043-7
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Protein
A0A0U1RPQ0
Organism: Mus musculus/domesticus
Length: 153  
Fragment?: true
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Protein
A0A0U1RQB3
Organism: Mus musculus/domesticus
Length: 95  
Fragment?: true
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Protein
A0A494BAU5
Organism: Mus musculus/domesticus
Length: 525  
Fragment?: true
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Publication
9343163 | -
First Author: Bischoff DS
Year: 1997
Journal: J Virol
Title: Molecular analysis of an enhancin gene in the Lymantria dispar nuclear polyhedrosis virus.
Volume: 71
Issue: 11
Pages: 8133-40
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Publication
16081094 | -
First Author: Galloway CS
Year: 2005
Journal: J Invertebr Pathol
Title: Comparison of the bacterial Enhancin-like proteins from Yersinia and Bacillus spp. with a baculovirus Enhancin.
Volume: 90
Issue: 2
Pages: 134-7
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Publication
16790012 | -
First Author: Hajaij-Ellouze M
Year: 2006
Journal: FEMS Microbiol Lett
Title: The enhancin-like metalloprotease from the Bacillus cereus group is regulated by the pleiotropic transcriptional activator PlcR but is not essential for larvicidal activity.
Volume: 260
Issue: 1
Pages: 9-16
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Publication
22238230 | -
First Author: Toprak U
Year: 2012
Journal: J Gen Virol
Title: Role of enhancin in Mamestra configurata nucleopolyhedrovirus virulence: selective degradation of host peritrophic matrix proteins.
Volume: 93
Issue: Pt 4
Pages: 744-753
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Publication
22299034 | -
First Author: Nakjang S
Year: 2012
Journal: PLoS One
Title: A novel extracellular metallopeptidase domain shared by animal host-associated mutualistic and pathogenic microbes.
Volume: 7
Issue: 1
Pages: e30287
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Publication
42311786 | J:388038
 
First Author: Yaman E
Year: 2026
Journal: Front Cell Neurosci
Title: Modulation of corneal sensory processing and pain responses by dry eye and corneal wounding.
Volume: 20
Pages: 1767673
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Publication
31413236 | J:290448
First Author: Horii Y
Year: 2019
Journal: Biomed Res
Title: Hypothermia induces changes in the alternative splicing pattern of cold-inducible RNA-binding protein transcripts in a non-hibernator, the mouse.
Volume: 40
Issue: 4
Pages: 153-161
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Protein
Q8R4D5
Organism: Mus musculus/domesticus
Length: 1104  
Fragment?: false
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Protein
Q9JJH7
Organism: Mus musculus/domesticus
Length: 1158  
Fragment?: false
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Protein
Q8BS44
Organism: Mus musculus/domesticus
Length: 1030  
Fragment?: true
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Protein
A0A494B8Z8
Organism: Mus musculus/domesticus
Length: 783  
Fragment?: false
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Protein
A0A494B9V5
Organism: Mus musculus/domesticus
Length: 894  
Fragment?: false
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Protein
J9SQG4
Organism: Mus musculus/domesticus
Length: 793  
Fragment?: false
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Protein
J9SUB2
Organism: Mus musculus/domesticus
Length: 783  
Fragment?: false
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Protein
Q8BJ11
Organism: Mus musculus/domesticus
Length: 737  
Fragment?: false
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Publication
11385575 | J:116354
First Author: Perraud AL
Year: 2001
Journal: Nature
Title: ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology.
Volume: 411
Issue: 6837
Pages: 595-9
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Protein
J9SQF3
Organism: Mus musculus/domesticus
Length: 1732  
Fragment?: false
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Protein
Q2TV84
Organism: Mus musculus/domesticus
Length: 1622  
Fragment?: false
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Protein
Q7TN37
Organism: Mus musculus/domesticus
Length: 1213  
Fragment?: false
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Protein
F4YJP8
Organism: Mus musculus/domesticus
Length: 1707  
Fragment?: false
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Protein
F4YJP9
Organism: Mus musculus/domesticus
Length: 1719  
Fragment?: false
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Protein
F4YJQ0
Organism: Mus musculus/domesticus
Length: 1719  
Fragment?: false
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Protein
F4YJQ1
Organism: Mus musculus/domesticus
Length: 1732  
Fragment?: false
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Protein
F4YJQ2
Organism: Mus musculus/domesticus
Length: 1689  
Fragment?: false
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Protein
F7CJ77
Organism: Mus musculus/domesticus
Length: 1579  
Fragment?: false
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Protein
J9S2Y6
Organism: Mus musculus/domesticus
Length: 1707  
Fragment?: false
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Protein
J9S314
Organism: Mus musculus/domesticus
Length: 1731  
Fragment?: false
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Protein
J9SVL3
Organism: Mus musculus/domesticus
Length: 1697  
Fragment?: false
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Protein
J9T120
Organism: Mus musculus/domesticus
Length: 1692  
Fragment?: false
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Protein
J9T143
Organism: Mus musculus/domesticus
Length: 1709  
Fragment?: false
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Protein
J9T334
Organism: Mus musculus/domesticus
Length: 1701  
Fragment?: false
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Protein
J9T345
Organism: Mus musculus/domesticus
Length: 1716  
Fragment?: false
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Protein
Q3UQF1
Organism: Mus musculus/domesticus
Length: 1579  
Fragment?: false
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Protein
Q69ZE8
Organism: Mus musculus/domesticus
Length: 1718  
Fragment?: true
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Protein
Q8BIH6
Organism: Mus musculus/domesticus
Length: 848  
Fragment?: false
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Protein
A0A0U1RPV6
Organism: Mus musculus/domesticus
Length: 1506  
Fragment?: false
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Protein
A0A0U1RQ32
Organism: Mus musculus/domesticus
Length: 1628  
Fragment?: false
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Protein
A0A494B964
Organism: Mus musculus/domesticus
Length: 1697  
Fragment?: false
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Protein
A0A494B967
Organism: Mus musculus/domesticus
Length: 1692  
Fragment?: false
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Protein
A0A494BAH7
Organism: Mus musculus/domesticus
Length: 1731  
Fragment?: false
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Protein
A0A494BAK8
Organism: Mus musculus/domesticus
Length: 848  
Fragment?: false
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Protein
A0A1B0GS49
Organism: Mus musculus/domesticus
Length: 1066  
Fragment?: false
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Protein
E9PUC8
Organism: Mus musculus/domesticus
Length: 958  
Fragment?: false
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Publication
15449545 | J:92574
First Author: Okazaki N
Year: 2004
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 11
Issue: 2
Pages: 127-35
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Publication
24029230 | J:202604
First Author: Nagamachi A
Year: 2013
Journal: Cancer Cell
Title: Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.
Volume: 24
Issue: 3
Pages: 305-17
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Publication
15368895 | J:92575
First Author: Okazaki N
Year: 2004
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 11
Issue: 3
Pages: 205-18
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Protein
Q91YD4
Organism: Mus musculus/domesticus
Length: 1506  
Fragment?: false
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Protein
Q3UYE9
Organism: Mus musculus/domesticus
Length: 807  
Fragment?: true
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Protein
Q8CIR4
Organism: Mus musculus/domesticus
Length: 2028  
Fragment?: false
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Protein
Q923J1
Organism: Mus musculus/domesticus
Length: 1863  
Fragment?: false
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Protein
A2AI57
Organism: Mus musculus/domesticus
Length: 1862  
Fragment?: false
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Protein
B9EK83
Organism: Mus musculus/domesticus
Length: 1863  
Fragment?: false
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Publication
12477932 | J:82808
First Author: Strausberg RL
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Volume: 99
Issue: 26
Pages: 16899-903
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:384794
     
First Author: MGI and IMPC
Year: 2026
Journal: Database Release
Title: MGI Load of Molecular Notes for Endonuclease-Mediated (CRISPR) Alleles from the International Mouse Phenotyping Consortium (IMPC)
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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Cambridge CB2 3EH, United Kingdom