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Search results 701 to 800 out of 1138 for Ucp1

0.025s
Type Details Score
Publication
First Author: Roth L
Year: 2024
Journal: Cell Rep
Title: Thyroid hormones are required for thermogenesis of beige adipocytes induced by Zfp423 inactivation.
Volume: 43
Issue: 12
Pages: 114987
Strain
Attribute String: mutant strain, transgenic, coisogenic
Publication
First Author: Lowell BB
Year: 1993
Journal: Nature
Title: Development of obesity in transgenic mice after genetic ablation of brown adipose tissue.
Volume: 366
Issue: 6457
Pages: 740-2
Publication
First Author: Klaus S
Year: 1998
Journal: Am J Physiol
Title: Physiology of transgenic mice with brown fat ablation: obesity is due to lowered body temperature.
Volume: 274
Issue: 2 Pt 2
Pages: R287-93
Publication
First Author: Mantzoros CS
Year: 1998
Journal: Diabetes
Title: Severe leptin resistance in brown fat-deficient uncoupling protein promoter-driven diphtheria toxin A mice despite suppression of hypothalamic neuropeptide Y and circulating corticosterone concentrations.
Volume: 47
Issue: 2
Pages: 230-8
Publication
First Author: Cittadini A
Year: 1999
Journal: Circulation
Title: Cardiovascular abnormalities in transgenic mice with reduced brown fat: an animal model of human obesity.
Volume: 100
Issue: 21
Pages: 2177-83
Publication
First Author: Gouon-Evans V
Year: 2002
Journal: Mol Endocrinol
Title: Unexpected deposition of brown fat in mammary gland during postnatal development.
Volume: 16
Issue: 11
Pages: 2618-27
Publication
First Author: Ortmann S
Year: 2003
Journal: Obes Res
Title: Self-selected macronutrient diet affects energy and glucose metabolism in brown fat-ablated mice.
Volume: 11
Issue: 12
Pages: 1536-44
Publication
First Author: Hamann A
Year: 1996
Journal: Endocrinology
Title: Decreased brown fat markedly enhances susceptibility to diet-induced obesity, diabetes, and hyperlipidemia.
Volume: 137
Issue: 1
Pages: 21-9
Publication
First Author: Melnyk A
Year: 1998
Journal: Am J Physiol
Title: Temperature-dependent feeding: lack of role for leptin and defect in brown adipose tissue-ablated obese mice.
Volume: 274
Issue: 4 Pt 2
Pages: R1131-5
Publication
First Author: Glantschnig C
Year: 2019
Journal: EMBO Rep
Title: The glucocorticoid receptor in brown adipocytes is dispensable for control of energy homeostasis.
Volume: 20
Issue: 11
Pages: e48552
Allele
Name: transgene insertion 445, Biomodels Austria
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
Publication
First Author: Perdikari A
Year: 2018
Journal: Cell Rep
Title: BATLAS: Deconvoluting Brown Adipose Tissue.
Volume: 25
Issue: 3
Pages: 784-797.e4
Publication  
First Author: Müller S
Year: 2020
Journal: Front Endocrinol (Lausanne)
Title: ESRRG and PERM1 Govern Mitochondrial Conversion in Brite/Beige Adipocyte Formation.
Volume: 11
Pages: 387
Allele
Name: transgene insertion 1, Evan Rosen
Allele Type: Transgenic
Attribute String: Recombinase
Allele
Name: uncoupling protein 1 (mitochondrial, proton carrier); endonuclease-mediated mutation 1, Hideyo Ohuchi
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout, Reporter
Strain
Attribute String: congenic, mutant strain, targeted mutation
Genotype
Symbol: Tg(UcpDta)1Kz/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Ckmm-Ucp1)1Boud/?
Background: involves: C57BL/6J * DBA/2J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Ckmm-Ucp1)1Boud/Tg(Ckmm-Ucp1)1Boud
Background: involves: C57BL/6J * DBA/2J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(UcpDta)1Kz/?
Background: FVB/N-Tg(UcpDta)1Kz/J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Ucp1/Ucp1<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Ucp1/Ucp1<+> Wtap/Wtap
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Knoll M
Year: 2017
Journal: Nat Commun
Title: SYK kinase mediates brown fat differentiation and activation.
Volume: 8
Issue: 1
Pages: 2115
Publication    
First Author: Zhang H
Year: 2024
Journal: Elife
Title: Perirenal adipose tissue contains a subpopulation of cold-inducible adipocytes derived from brown-to-white conversion.
Volume: 13
Publication  
First Author: Claflin KE
Year: 2022
Journal: Mol Metab
Title: Conditional gene targeting using UCP1-Cre mice directly targets the central nervous system beyond thermogenic adipose tissues.
Volume: 55
Pages: 101405
Publication
First Author: Ohashi N
Year: 2017
Journal: Diabetes
Title: Pivotal Role of O-GlcNAc Modification in Cold-Induced Thermogenesis by Brown Adipose Tissue Through Mitochondrial Biogenesis.
Volume: 66
Issue: 9
Pages: 2351-2362
Publication
First Author: Guilherme A
Year: 2017
Journal: Mol Metab
Title: Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming.
Volume: 6
Issue: 8
Pages: 781-796
Publication
First Author: Jung SM
Year: 2019
Journal: Mol Cell
Title: Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1.
Volume: 75
Issue: 4
Pages: 807-822.e8
Publication
First Author: Yi D
Year: 2019
Journal: Cell Rep
Title: Zc3h10 Acts as a Transcription Factor and Is Phosphorylated to Activate the Thermogenic Program.
Volume: 29
Issue: 9
Pages: 2621-2633.e4
Publication
First Author: Keinan O
Year: 2021
Journal: Nature
Title: Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes.
Volume: 599
Issue: 7884
Pages: 296-301
Publication
First Author: Sanchez-Gurmaches J
Year: 2018
Journal: Cell Metab
Title: Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis.
Volume: 27
Issue: 1
Pages: 195-209.e6
Publication
First Author: Yoshizawa T
Year: 2022
Journal: Nat Commun
Title: SIRT7 suppresses energy expenditure and thermogenesis by regulating brown adipose tissue functions in mice.
Volume: 13
Issue: 1
Pages: 7439
Publication
First Author: Rahbani JF
Year: 2021
Journal: Nature
Title: Creatine kinase B controls futile creatine cycling in thermogenic fat.
Volume: 590
Issue: 7846
Pages: 480-485
Publication
First Author: Chen CM
Year: 2023
Journal: J Lipid Res
Title: Brown adipocyte mineralocorticoid receptor deficiency impairs metabolic regulation in diet-induced obese mice.
Volume: 64
Issue: 11
Pages: 100449
Publication
First Author: Viana-Huete V
Year: 2016
Journal: Endocrinology
Title: Essential Role of IGFIR in the Onset of Male Brown Fat Thermogenic Function: Regulation of Glucose Homeostasis by Differential Organ-Specific Insulin Sensitivity.
Volume: 157
Issue: 4
Pages: 1495-511
Publication
First Author: Lee JH
Year: 2021
Journal: PLoS One
Title: GHS-R in brown fat potentiates differential thermogenic responses under metabolic and thermal stresses.
Volume: 16
Issue: 4
Pages: e0249420
Strain
Attribute String: congenic, mutant strain, transgenic
Publication
First Author: Fan L
Year: 2022
Journal: iScience
Title: KLF15 controls brown adipose tissue transcriptional flexibility and metabolism in response to various energetic demands.
Volume: 25
Issue: 11
Pages: 105292
Publication      
First Author: Rosen
Year: 2014
Journal: MGI Direct Data Submission
Title: Generation of a Ucp1-cre transgene
Publication
First Author: Flicker D
Year: 2019
Journal: Cell Rep
Title: Exploring the In Vivo Role of the Mitochondrial Calcium Uniporter in Brown Fat Bioenergetics.
Volume: 27
Issue: 5
Pages: 1364-1375.e5
Allele
Name: transgene insertion, Jens C Bruning
Allele Type: Transgenic
Attribute String: Recombinase
Strain
Attribute String: endonuclease-mediated mutation, mutant stock
Genotype
Symbol: Tg(Ucp1-cre)1Evdr/?
Background: involves: FVB
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Kdm1a/Kdm1a Tg(Ucp1-cre)14Bnto/?
Background: involves: C57BL/6N * FVB/NJ
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: DiStefano MT
Year: 2016
Journal: Mol Metab
Title: Adipocyte-specific Hypoxia-inducible gene 2 promotes fat deposition and diet-induced insulin resistance.
Volume: 5
Issue: 12
Pages: 1149-1161
Publication
First Author: Liu K
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Scd1 controls de novo beige fat biogenesis through succinate-dependent regulation of mitochondrial complex II.
Volume: 117
Issue: 5
Pages: 2462-2472
Publication
First Author: Paulo E
Year: 2018
Journal: Sci Rep
Title: Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis.
Volume: 8
Issue: 1
Pages: 11001
Publication
First Author: Vidal-Puig A
Year: 1996
Journal: J Clin Invest
Title: Regulation of PPAR gamma gene expression by nutrition and obesity in rodents.
Volume: 97
Issue: 11
Pages: 2553-61
Publication  
First Author: Ilkun O
Year: 2015
Journal: J Mol Cell Cardiol
Title: Antioxidant treatment normalizes mitochondrial energetics and myocardial insulin sensitivity independently of changes in systemic metabolic homeostasis in a mouse model of the metabolic syndrome.
Volume: 85
Pages: 104-16
Publication
First Author: Lasar D
Year: 2018
Journal: Cell Rep
Title: Peroxisome Proliferator Activated Receptor Gamma Controls Mature Brown Adipocyte Inducibility through Glycerol Kinase.
Volume: 22
Issue: 3
Pages: 760-773
Publication
First Author: Mahdaviani K
Year: 2017
Journal: EMBO Rep
Title: Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis.
Volume: 18
Issue: 7
Pages: 1123-1138
Publication
First Author: Liu P
Year: 2017
Journal: Nature
Title: Blocking FSH induces thermogenic adipose tissue and reduces body fat.
Volume: 546
Issue: 7656
Pages: 107-112
Publication  
First Author: Huang Y
Year: 2022
Journal: J Clin Invest
Title: Brown adipose TRX2 deficiency activates mtDNA-NLRP3 to impair thermogenesis and protect against diet-induced insulin resistance.
Volume: 132
Issue: 9
Publication  
First Author: Hasan N
Year: 2021
Journal: Mol Metab
Title: Brown adipocyte-specific knockout of Bmal1 causes mild but significant thermogenesis impairment in mice.
Volume: 49
Pages: 101202
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Ucp1-cre)1Evdr/?
Background: involves: 129 * C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Crls1/Crls1 Tg(Ucp1-cre/ERT2)426Biat/?
Background: involves: C57BL/6N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Slc25a44/Slc25a44 Tg(Ucp1-cre)1Evdr/?
Background: involves: C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdk7/Cdk7 Tg(Ucp1-cre)1Evdr/?
Background: involves: 129S2/SvPas * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Opa1/Opa1 Tg(Ucp1-cre)1Evdr/?
Background: involves: 129S/SvEv * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Lehr L
Year: 2004
Journal: FEBS Lett
Title: Control of 4E-BP1 expression in mouse brown adipose tissue by the beta3-adrenoceptor.
Volume: 576
Issue: 1-2
Pages: 179-82
Publication
First Author: De Sousa-Coelho AL
Year: 2013
Journal: J Lipid Res
Title: FGF21 mediates the lipid metabolism response to amino acid starvation.
Volume: 54
Issue: 7
Pages: 1786-97
Publication
First Author: Nedergaard J
Year: 2014
Journal: Cell Metab
Title: The browning of white adipose tissue: some burning issues.
Volume: 20
Issue: 3
Pages: 396-407
Publication
First Author: Chouchani ET
Year: 2017
Journal: J Biol Chem
Title: Mitochondrial reactive oxygen species and adipose tissue thermogenesis: Bridging physiology and mechanisms.
Volume: 292
Issue: 41
Pages: 16810-16816
Publication    
First Author: Benitez GJ
Year: 2020
Journal: J Vis Exp
Title: Isolation of Adipose Tissue Nuclei for Single-Cell Genomic Applications.
Issue: 160
Publication
First Author: Fu L
Year: 2004
Journal: Endocrinology
Title: Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes.
Volume: 145
Issue: 6
Pages: 2594-603
Publication  
First Author: Zhou L
Year: 2015
Journal: Nat Commun
Title: Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice.
Volume: 6
Pages: 5949
Publication
First Author: Chen Z
Year: 2008
Journal: Arterioscler Thromb Vasc Biol
Title: Alterations in hepatic metabolism in fld mice reveal a role for lipin 1 in regulating VLDL-triacylglyceride secretion.
Volume: 28
Issue: 10
Pages: 1738-44
Publication
First Author: Duncan JG
Year: 2007
Journal: Circulation
Title: Insulin-resistant heart exhibits a mitochondrial biogenic response driven by the peroxisome proliferator-activated receptor-alpha/PGC-1alpha gene regulatory pathway.
Volume: 115
Issue: 7
Pages: 909-17
Publication  
First Author: Colas C
Year: 2023
Journal: Mol Metab
Title: DEPTOR loss impairs brown adipocyte development in vitro but has limited impacts in mice.
Volume: 67
Pages: 101660
Publication
First Author: Chakravarthy MV
Year: 2008
Journal: Diabetes
Title: Decreased fetal size is associated with beta-cell hyperfunction in early life and failure with age.
Volume: 57
Issue: 10
Pages: 2698-707
Publication
First Author: Siri P
Year: 2001
Journal: J Biol Chem
Title: Post-transcriptional stimulation of the assembly and secretion of triglyceride-rich apolipoprotein B lipoproteins in a mouse with selective deficiency of brown adipose tissue, obesity, and insulin resistance.
Volume: 276
Issue: 49
Pages: 46064-72
Publication
First Author: Zhang YL
Year: 2006
Journal: J Biol Chem
Title: Aberrant hepatic expression of PPARgamma2 stimulates hepatic lipogenesis in a mouse model of obesity, insulin resistance, dyslipidemia, and hepatic steatosis.
Volume: 281
Issue: 49
Pages: 37603-15
Publication
First Author: Gómez-Hernández A
Year: 2016
Journal: Endocrinology
Title: Severe Brown Fat Lipoatrophy Aggravates Atherosclerotic Process in Male Mice.
Volume: 157
Issue: 9
Pages: 3517-28
Publication
First Author: Viana-Huete V
Year: 2018
Journal: Endocrinology
Title: Male Brown Fat-Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity.
Volume: 159
Issue: 1
Pages: 323-340
Publication
First Author: Gómez-Hernández A
Year: 2012
Journal: Endocrinology
Title: Brown fat lipoatrophy and increased visceral adiposity through a concerted adipocytokines overexpression induces vascular insulin resistance and dysfunction.
Volume: 153
Issue: 3
Pages: 1242-55
Publication
First Author: Krishnan J
Year: 2012
Journal: Genes Dev
Title: Dietary obesity-associated Hif1α activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system.
Volume: 26
Issue: 3
Pages: 259-70
Publication
First Author: Xiong W
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Brown Adipocyte-Specific PPARγ (Peroxisome Proliferator-Activated Receptor γ) Deletion Impairs Perivascular Adipose Tissue Development and Enhances Atherosclerosis in Mice.
Volume: 38
Issue: 8
Pages: 1738-1747
Publication  
First Author: Li F
Year: 2021
Journal: Life (Basel)
Title: Brown Fat Dnmt3b Deficiency Ameliorates Obesity in Female Mice.
Volume: 11
Issue: 12
Publication    
First Author: Marmol P
Year: 2020
Journal: Elife
Title: Control of brown adipose tissue adaptation to nutrient stress by the activin receptor ALK7.
Volume: 9
Publication
First Author: Tolson KP
Year: 2020
Journal: FASEB J
Title: Conditional knockout of kisspeptin signaling in brown adipose tissue increases metabolic rate and body temperature and lowers body weight.
Volume: 34
Issue: 1
Pages: 107-121
Publication
First Author: Yoshida Y
Year: 2022
Journal: Sci Rep
Title: Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism.
Volume: 12
Issue: 1
Pages: 14883
Publication
First Author: Sebag SC
Year: 2021
Journal: Cell Rep
Title: ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue.
Volume: 37
Issue: 7
Pages: 110003
Publication
First Author: Tharp KM
Year: 2018
Journal: Cell Metab
Title: Actomyosin-Mediated Tension Orchestrates Uncoupled Respiration in Adipose Tissues.
Volume: 27
Issue: 3
Pages: 602-615.e4
Publication
First Author: Bjorkman SH
Year: 2024
Journal: Sci Rep
Title: ATF4 expression in thermogenic adipocytes is required for cold-induced thermogenesis in mice via FGF21-independent mechanisms.
Volume: 14
Issue: 1
Pages: 1563
Publication
First Author: Verkerke ARP
Year: 2024
Journal: Cell
Title: BCAA-nitrogen flux in brown fat controls metabolic health independent of thermogenesis.
Volume: 187
Issue: 10
Pages: 2359-2374.e18
Genotype
Symbol: Tg(APOB)11Rub/? Tg(UcpDta)1Kz/?
Background: involves: C57BL/6J * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Irf4/Irf4 Tg(Ucp1-cre)1Evdr/?
Background: involves: 129S1/Sv * C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pparg/Pparg Tg(Ucp1-cre)1Evdr/?
Background: involves: 129S4/SvJae * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pex16/Pex16 Tg(Ucp1-cre)1Evdr/?
Background: involves: C57BL/6N * FVB * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Yy1/Yy1 Tg(Ucp1-cre)1Evdr/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Ucp1/Ucp1<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Prkd1/Prkd1 Tg(Ucp1-cre)1Evdr/?
Background: involves: 129S/SvEv * C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Stx4a/Stx4a Tg(Ucp1-cre)1Evdr/?
Background: involves: C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mettl14/Mettl14 Tg(Ucp1-cre)1Evdr/?
Background: involves: 129 * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Boström P
Year: 2012
Journal: Nature
Title: A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis.
Volume: 481
Issue: 7382
Pages: 463-8
Publication
First Author: Yamada M
Year: 1998
Journal: FEBS Lett
Title: Genomic organization and promoter function of the mouse uncoupling protein 2 (UCP2) gene.
Volume: 432
Issue: 1-2
Pages: 65-9
Publication
First Author: Damal Villivalam S
Year: 2020
Journal: Nat Commun
Title: TET1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis.
Volume: 11
Issue: 1
Pages: 4313
Publication
First Author: Chung KJ
Year: 2017
Journal: Nat Immunol
Title: A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity.
Volume: 18
Issue: 6
Pages: 654-664
Publication
First Author: Li H
Year: 2021
Journal: Biochim Biophys Acta Mol Cell Res
Title: Peripheral IL-6/STAT3 signaling promotes beiging of white fat.
Volume: 1868
Issue: 10
Pages: 119080