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Search results 701 to 800 out of 803 for Zic2

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Type Details Score
Publication
First Author: Bailey PJ
Year: 2006
Journal: Exp Cell Res
Title: A global genomic transcriptional code associated with CNS-expressed genes.
Volume: 312
Issue: 16
Pages: 3108-19
Publication      
First Author: Freeman TC
Year: 1998
Journal: MGI Direct Data Submission
Title: Expression Mapping of Mouse Genes
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
GXD Expression      
Probe: MGI:5289047
Assay Type: RT-PCR
Annotation Date: 2017-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:5823398
Age: embryonic day 7.0
Specimen Label: Zic2 +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5289047
Assay Type: RT-PCR
Annotation Date: 2017-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:5823398
Age: embryonic day 7.0
Specimen Label: Zic2 Ku/Ku
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5288877
Assay Type: RT-PCR
Annotation Date: 2017-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:5823399
Age: embryonic day 7.0
Specimen Label: Zic2 +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5288877
Assay Type: RT-PCR
Annotation Date: 2017-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:5823399
Age: embryonic day 7.0
Specimen Label: Zic2 Ku/Ku
Detected: true
Specimen Num: 2
Genotype
Symbol: Zic2/Zic2
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Allele
Name: zinc finger protein of the cerebellum 2; targeted mutation 1, Jun Aruga
Allele Type: Targeted
Attribute String: Hypomorph
Allele  
Name: zinc finger protein of the cerebellum 2; kumba
Allele Type: Chemically induced (ENU)
Interaction Experiment
Description: A role for Zic1 and Zic2 in Myf5 regulation and somite myogenesis.
Genotype
Symbol: Zic2/Zic2
Background: C3.CAnNCrl-Zic2
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Zic2/Zic2
Background: 129S.CAnNCrl(C3)-Zic2
Zygosity: hm
Has Mutant Allele: true
DO Term
Allele
Name: zinc finger protein of the cerebellum 2; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
GXD Expression    
Probe: MGI:23226
Assay Type: RNA in situ
Annotation Date: 2017-02-07
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5823402
Age: embryonic day 9.5
Note: Decreasing Nodal function on the Zic2 Ku background leads to moderate or severe truncation.
Specimen Label: 1I
Specimen Num: 9
GXD Expression    
Probe: MGI:23226
Assay Type: RNA in situ
Annotation Date: 2017-02-07
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1664015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5823402
Age: embryonic day 9.5
Note: Decreasing Nodal function on the Zic2 Ku background leads to moderate or severe truncation.
Specimen Label: 1I
Specimen Num: 9
GXD Expression  
Probe: MGI:7709414
Assay Type: RNA in situ
Annotation Date: 2024-08-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1716824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7709441
Age: embryonic day 16.5
Note: Highly expressed in ventral areas, excluded from the most peripheral region. Unc5c and Zic2 were expressed in mutually exclusive patterns.
Specimen Label: 5A/A'
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:23226
Assay Type: RNA in situ
Annotation Date: 2017-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5823402
Age: embryonic day 9.5
Note: Embryos heterozygous for the severe loss of function kumba (Ku) allele of Zic2 have no discernible phenotype.
Specimen Label: 1D
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:23226
Assay Type: RNA in situ
Annotation Date: 2017-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1664015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5823402
Age: embryonic day 9.5
Note: Embryos heterozygous for the severe loss of function kumba (Ku) allele of Zic2 have no discernible phenotype.
Specimen Label: 1D
Detected: true
Specimen Num: 4
Allele
Name: zinc finger protein of the cerebellum 2; endonuclease-mediated mutation 1, Kenneth R Chien
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: zinc finger protein of the cerebellum 2; endonuclease-mediated mutation 2, Kenneth R Chien
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
GXD Expression    
Probe: MGI:23226
Assay Type: RNA in situ
Annotation Date: 2017-02-07
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1664015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5823402
Age: embryonic day 9.5
Note: Embryos homozygous for the severe loss of function kumba (Ku) allele of Zic2 exhibit forebrain dysmorphology that can include a mild loss of telencephalic tissue.
Specimen Label: 1E
Specimen Num: 5
Publication
First Author: Vural B
Year: 2005
Journal: Cancer
Title: Frequency of SOX Group B (SOX1, 2, 3) and ZIC2 antibodies in Turkish patients with small cell lung carcinoma and their correlation with clinical parameters.
Volume: 103
Issue: 12
Pages: 2575-83
GXD Expression
Probe: MGI:2149733
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7708043
Age: embryonic day 15.5
Image: 1a
Note: Expression was detected in postmitotic retinal ganglion cells (RGC's) in the ventrotemporal retina. Co-label with Zic2 was seen in ipsilateral RGC's. Few of the RGC's were co-labeled with EdU when injected at E11.
Specimen Label: 1a
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:2149733
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7708043
Age: embryonic day 15.5
Image: 1e
Note: Expression was detected in postmitotic retinal ganglion cells in the ventrotemporal retina. Co-label with Zic2 was seen in ipsilateral RGC's. Few of the RGC's were co-labeled with EdU when injected at E12.
Specimen Label: 1e
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:2149733
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7708043
Age: embryonic day 15.5
Image: 1i
Note: Expression was detected in postmitotic retinal ganglion cells in the ventrotemporal retina. Co-label with Zic2 was seen in ipsilateral RGC's. The number of RGC's co-labeled with EdU was higher when injected at E13 than when injected at previous ages.
Specimen Label: 1i
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:2149733
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7708043
Age: embryonic day 15.5
Image: 1m
Note: Expression was detected in postmitotic retinal ganglion cells in the ventrotemporal retina. Co-label with Zic2 was seen in ipsilateral RGC's. The number of RGC's co-labeled with EdU was highest when injected at E14 than when injected at previous ages.
Specimen Label: 1m
Detected: true
Specimen Num: 4
Allele
Name: zinc finger protein of the cerebellum 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Allele
Name: transgene insertion HT146, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 1453, Rudiger Klein
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
HT Experiment
Series Id: GSE60731
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: targeted mutation, mutant strain, congenic
Strain
Attribute String: mutant stock, transgenic
Strain
Attribute String: coisogenic, mutant strain, transgenic
Allele
Name: transgene insertion 1463, Rudiger Klein
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Genotype
Symbol: Zic2/Zic2<+>
Background: B6.129S4-Zic2
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Zic2/Zic2<+>
Background: involves: 129S4/SvJae * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Zic2/Zic2<+>
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Zic2/Zic2
Background: involves: 129S4/SvJae * BALB/c * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Zic2/Zic2
Background: B6.129S4-Zic2
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Zic2/Zic2
Background: involves: 129S4/SvJae
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Zic2/Zic2<+>
Background: involves: 129S4/SvJae
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Zic2/Zic2<+>
Background: involves: 129S4/SvJae * BALB/c * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Paixão S
Year: 2019
Journal: Neuron
Title: Identification of Spinal Neurons Contributing to the Dorsal Column Projection Mediating Fine Touch and Corrective Motor Movements.
Volume: 104
Issue: 4
Pages: 749-764.e6
Genotype
Symbol: Zic1/Zic1<+> Zic2/Zic2<+>
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Zic2/Zic2<+> Zic3/?
Background: involves: 129S4/SvJae * BNT/LeJ * Balb/c * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Zic1/Zic1<+> Zic2/Zic2<+>
Background: involves: 129S4/SvJae
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Zic2/Zic2 Zic3/?
Background: involves: 129S4/SvJae * BNT/LeJ * Balb/c * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Martindill DM
Year: 2007
Journal: Nat Cell Biol
Title: Nucleolar release of Hand1 acts as a molecular switch to determine cell fate.
Volume: 9
Issue: 10
Pages: 1131-41
Protein
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: false
Publication
First Author: Kusano S
Year: 2002
Journal: Mol Cell Biol
Title: I-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways.
Volume: 22
Issue: 18
Pages: 6393-405
Protein
Organism: Mus musculus/domesticus
Length: 251  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 68  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 200  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 143  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 153  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 186  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 124  
Fragment?: true
Publication
First Author: Thébault S
Year: 2000
Journal: J Biol Chem
Title: Molecular cloning of a novel human I-mfa domain-containing protein that differently regulates human T-cell leukemia virus type I and HIV-1 expression.
Volume: 275
Issue: 7
Pages: 4848-57
Publication
First Author: Gautier VW
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Direct interaction of the human I-mfa domain-containing protein, HIC, with HIV-1 Tat results in cytoplasmic sequestration and control of Tat activity.
Volume: 102
Issue: 45
Pages: 16362-7
Publication
First Author: Young TM
Year: 2003
Journal: Mol Cell Biol
Title: The human I-mfa domain-containing protein, HIC, interacts with cyclin T1 and modulates P-TEFb-dependent transcription.
Volume: 23
Issue: 18
Pages: 6373-84
Protein Domain
Type: Family
Description: This family consists of MyoD family inhibitor (I-mfa, MDFI) and MyoD family inhibitor domain-containing protein. I-mfa acts as a transcriptional activator or repressor. It retains nuclear Zic family proteins (ZIC1, ZIC2 and ZIC3) in the cytoplasm and consequently inhibits their transcriptional activation ability []. I-mfa domain-containing protein interacts with HAND1 (bHLH transcription factor), leading to sequester HAND1 into the nucleolus and prevent its activity []. In humans modulates the expression from both cellular and viral promoters. It down-regulates Tat-dependent transcription of the human immunodeficiency virus type 1 (HIV-1) LTR by interacting with HIV-1 Tat and Rev and impairing their nuclear import, probably by rendering the NLS domains inaccessible to importin-beta. It also stimulates activation of human T-cell leukemia virus type I (HTLV-I) LTR [, , ]. Both I-mfa and I-mfa domain-containing protein interact with the axin complex and affect axin regulation of both the Wnt and the JNK activation pathways [].
Publication
First Author: Brown SA
Year: 1998
Journal: Nat Genet
Title: Holoprosencephaly due to mutations in ZIC2, a homologue of Drosophila odd-paired.
Volume: 20
Issue: 2
Pages: 180-3
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Zic2-cre/ERT2)1453Kln/?
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Aruga J
Year: 1996
Journal: Gene
Title: Identification and characterization of Zic4, a new member of the mouse Zic gene family.
Volume: 172
Issue: 2
Pages: 291-4
Publication
First Author: Sanchez-Ferras O
Year: 2014
Journal: Biochim Biophys Acta
Title: Induction and dorsal restriction of Paired-box 3 (Pax3) gene expression in the caudal neuroectoderm is mediated by integration of multiple pathways on a short neural crest enhancer.
Volume: 1839
Issue: 7
Pages: 546-58