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Search results 701 to 800 out of 828 for Zic3

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Type Details Score
Publication
First Author: Gurdziel K
Year: 2016
Journal: Dev Dyn
Title: Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.
Volume: 245
Issue: 5
Pages: 614-26
Publication
First Author: Lewandowski JP
Year: 2015
Journal: Dev Biol
Title: Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Volume: 406
Issue: 1
Pages: 92-103
Publication
First Author: Shimogori T
Year: 2010
Journal: Nat Neurosci
Title: A genomic atlas of mouse hypothalamic development.
Volume: 13
Issue: 6
Pages: 767-75
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Tang F
Year: 2011
Journal: PLoS One
Title: Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
Volume: 6
Issue: 6
Pages: e21208
Publication
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
GXD Expression      
Probe: MGI:6430367
Assay Type: RT-PCR
Annotation Date: 2020-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677919
Stage: TS19
Assay Id: MGI:6430380
Age: embryonic day 11.5
Specimen Label: Zic3 null
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6430367
Assay Type: RT-PCR
Annotation Date: 2020-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677919
Stage: TS19
Assay Id: MGI:6430380
Age: embryonic day 11.5
Specimen Label: Zic3 null;Gli3+/-
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6430367
Assay Type: RT-PCR
Annotation Date: 2020-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677919
Stage: TS19
Assay Id: MGI:6430380
Age: embryonic day 11.5
Specimen Label: Zic3 null;Gli3-/-
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2684476
Assay Type: Western blot
Annotation Date: 2020-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640619
Stage: TS19
Assay Id: MGI:6430387
Age: embryonic day 11.5
Specimen Label: Zic3 null;Gli3+/-
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2684476
Assay Type: Western blot
Annotation Date: 2020-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640619
Stage: TS19
Assay Id: MGI:6430387
Age: embryonic day 11.5
Specimen Label: Zic3 null;Gli3+/-
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:7277835
Assay Type: RT-PCR
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Stage: TS12
Assay Id: MGI:7277845
Age: embryonic day 8.0
Specimen Label: Zic3 null
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7277836
Assay Type: RT-PCR
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Stage: TS12
Assay Id: MGI:7277846
Age: embryonic day 8.0
Specimen Label: Zic3 null
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7277837
Assay Type: RT-PCR
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Stage: TS12
Assay Id: MGI:7277847
Age: embryonic day 8.0
Specimen Label: Zic3 null
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7277838
Assay Type: RT-PCR
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Stage: TS12
Assay Id: MGI:7277848
Age: embryonic day 8.0
Specimen Label: Zic3 null
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7277839
Assay Type: RT-PCR
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Stage: TS12
Assay Id: MGI:7277849
Age: embryonic day 8.0
Specimen Label: Zic3 null
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7277840
Assay Type: RT-PCR
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Stage: TS12
Assay Id: MGI:7277850
Age: embryonic day 8.0
Specimen Label: Zic3 null
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7277841
Assay Type: RT-PCR
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Stage: TS12
Assay Id: MGI:7277851
Age: embryonic day 8.0
Specimen Label: Zic3 null
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7277842
Assay Type: RT-PCR
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Stage: TS12
Assay Id: MGI:7277852
Age: embryonic day 8.0
Specimen Label: Zic3 null
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7277832
Assay Type: Western blot
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:7277853
Age: embryonic day 10.5
Specimen Label: Zic3 null
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7277832
Assay Type: Western blot
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:7277853
Age: embryonic day 10.5
Specimen Label: Zic3 null
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7277832
Assay Type: Western blot
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:7277853
Age: embryonic day 10.5
Specimen Label: Zic3 null
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7277832
Assay Type: Western blot
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:7277853
Age: embryonic day 10.5
Specimen Label: Zic3 null
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7277833
Assay Type: Western blot
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:7277854
Age: embryonic day 10.5
Specimen Label: Zic3 null
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7277833
Assay Type: Western blot
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:7277854
Age: embryonic day 10.5
Specimen Label: Zic3 null
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7277833
Assay Type: Western blot
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:7277854
Age: embryonic day 10.5
Specimen Label: Zic3 null
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7277833
Assay Type: Western blot
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:7277854
Age: embryonic day 10.5
Specimen Label: Zic3 null
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7277834
Assay Type: Western blot
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:7277855
Age: embryonic day 10.5
Specimen Label: Zic3 null
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7277834
Assay Type: Western blot
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:7277855
Age: embryonic day 10.5
Specimen Label: Zic3 null
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7277834
Assay Type: Western blot
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:7277855
Age: embryonic day 10.5
Specimen Label: Zic3 null
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7277834
Assay Type: Western blot
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:7277855
Age: embryonic day 10.5
Specimen Label: Zic3 null
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:7277831
Assay Type: Immunohistochemistry
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:7277843
Age: embryonic day 8.0
Note: Node cells less elongated than in wild type.
Specimen Label: S1 Zic3 null
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7277831
Assay Type: Immunohistochemistry
Annotation Date: 2022-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:7277844
Age: embryonic day 8.0
Note: Node cells less elongated than in wild type.
Specimen Label: S1 Zic3 null
Detected: true
Specimen Num: 4
Interaction Experiment
Description: Preaxial polydactyly caused by Gli3 haploinsufficiency is rescued by Zic3 loss of function in mice.
DO Term
Publication
First Author: Bedard JE
Year: 2011
Journal: PLoS One
Title: Identification of a novel ZIC3 isoform and mutation screening in patients with heterotaxy and congenital heart disease.
Volume: 6
Issue: 8
Pages: e23755
Allele  
Name: zinc finger protein of the cerebellum 3; bent tail
Allele Type: Spontaneous
DO Term
Strain
Attribute String: mutant stock
Strain
Attribute String: F1 hybrid, mutant stock
Strain
Attribute String: inbred strain, spontaneous mutation
Allele
Name: zinc finger protein of the cerebellum 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Genotype
Symbol: Zic3/Zic3<+>
Background: BNT/LeJ
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Zic3/Zic3
Background: BNT/LeJ
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Zic3/?
Background: involves: BNT/LeJ * C57BL/6J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Zic3/?
Background: involves: BNT/LeJ * Balb/c * C57BL/6J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Zic3/Zic3
Background: involves: BNT/LeJ * Balb/c * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Allele
Name: transgene insertion KM21, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: F1 hybrid, mutant stock
Strain
Attribute String: mutant stock, transgenic
Genotype
Symbol: Zic2/Zic2<+> Zic3/?
Background: involves: 129S4/SvJae * BNT/LeJ * Balb/c * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Zic2/Zic2 Zic3/?
Background: involves: 129S4/SvJae * BNT/LeJ * Balb/c * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 181  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: true
Protein Domain
Type: Domain
Description: This is the ZF1 (Zinc Finger 1) domain found in Zic family proteins found in Eukaryotes. In humans, there are five members of the Zic family that are involved in human congenital anomalies. One of them, ZIC3, causes X-linked heterotaxy (HTX1), which is a left-right axis disturbance that manifests as variable combinations of heart malformation, altered lung lobation, splenic abnormality and gastrointestinal malrotation. Zic faily proteins contain multiple zinc finger domains (ZFD), which are generally composed of five tandemly repeated C2H2 zinc finger (ZF) motifs. Sequence comparison analysis reveal that this N-terminal ZF (ZF1) domain of the Zic zinc finger domains is unique in that it possesses more amino acid residues (6-38 amino acids) between the two cysteine residues of the C2H2 motif compared to Gli and Glis ZF1s or any of the other ZFs (ZF2-5) in the Gli/Glis/Zic superfamily of proteins. Mutations in cysteine 253 (C253S) or histidine 286 (H286R) in ZIC3 ZF1, which are found in heterotaxy patients, result in extranuclear localization of the mutant ZIC3 protein. Furthermore, mutations in the evolutionarily conserved amino acid residues (C253, W255, C268, H281 and H286) of ZF1 generally impair nuclear localization [].
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
Allele  
Name: ATPase, copper transporting, alpha polypeptide; tortoiseshell
Allele Type: Spontaneous
Publication
First Author: Ishiguro A
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family.
Volume: 324
Issue: 1
Pages: 302-7
Publication
First Author: Vetter K
Year: 2001
Journal: Mech Dev
Title: Expression of a novel mouse gene 'mbFZb' in distinct regions of the developing nervous system and the adult brain.
Volume: 100
Issue: 1
Pages: 123-5
Publication
First Author: Yanagida K
Year: 2020
Journal: Dev Cell
Title: Sphingosine 1-Phosphate Receptor Signaling Establishes AP-1 Gradients to Allow for Retinal Endothelial Cell Specialization.
Volume: 52
Issue: 6
Pages: 779-793.e7
Strain
Attribute String: inbred strain, spontaneous mutation
Strain
Attribute String: mutant stock, spontaneous mutation
Strain
Attribute String: congenic, mutant strain
Strain
Attribute String: mutant strain
Publication
First Author: Dickie MM
Year: 1954
Journal: J Hered
Title: The Tortoise Shell House Mouse.
Volume: 45
Issue: 4
Pages: 158-90
Publication
First Author: Gacheru S
Year: 1993
Journal: Arch Biochem Biophys
Title: Expression and accumulation of lysyl oxidase, elastin, and type I procollagen in human Menkes and mottled mouse fibroblasts.
Volume: 301
Issue: 2
Pages: 325-9
Publication
First Author: Sheedlo HJ
Year: 1982
Journal: J Anat
Title: SEM analysis of body hairs and whiskers of heterozygous tortoiseshell (Moto/+) female mice (Mus musculus).
Volume: 135
Issue: Pt 1
Pages: 211-6
Publication
First Author: Sheedlo HJ
Year: 1981
Journal: Genet Res
Title: Copper localization in the duodenal mucosa of heterozygous tortoiseshell (Moto/+) female mice (Mus musculus).
Volume: 38
Issue: 3
Pages: 333-6
Publication
First Author: Erdman MD
Year: 1987
Journal: Growth
Title: Effects of the sex-linked prenatal lethal gene tortoise (Moto) on reproduction and growth in the mouse.
Volume: 51
Issue: 2
Pages: 189-97