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Search results 7101 to 7200 out of 8285 for C2

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Type Details Score
Publication
First Author: Lo YL
Year: 2009
Journal: Mamm Genome
Title: Diversification of TOLLIP isoforms in mouse and man.
Volume: 20
Issue: 5
Pages: 305-14
Publication
First Author: Zhang T
Year: 2009
Journal: J Cell Sci
Title: Microtubule plus-end binding protein EB1 is necessary for muscle cell differentiation, elongation and fusion.
Volume: 122
Issue: Pt 9
Pages: 1401-9
Publication
First Author: Lamour NF
Year: 2009
Journal: J Biol Chem
Title: Ceramide 1-phosphate is required for the translocation of group IVA cytosolic phospholipase A2 and prostaglandin synthesis.
Volume: 284
Issue: 39
Pages: 26897-907
Publication
First Author: Nagamoto-Combs K
Year: 2010
Journal: J Neurosci
Title: Microglial phenotype is regulated by activity of the transcription factor, NFAT (nuclear factor of activated T cells).
Volume: 30
Issue: 28
Pages: 9641-6
Publication
First Author: Marín-Vicente C
Year: 2008
Journal: J Mol Biol
Title: The PtdIns(4,5)P2 ligand itself influences the localization of PKCalpha in the plasma membrane of intact living cells.
Volume: 377
Issue: 4
Pages: 1038-52
Publication
First Author: Kumar A
Year: 2011
Journal: Mol Cell Biol
Title: Nuclear but not cytosolic phosphoinositide 3-kinase beta has an essential function in cell survival.
Volume: 31
Issue: 10
Pages: 2122-33
Publication
First Author: Gardner S
Year: 2011
Journal: Mol Endocrinol
Title: TGF-β inhibits muscle differentiation by blocking autocrine signaling pathways initiated by IGF-II.
Volume: 25
Issue: 1
Pages: 128-37
Publication
First Author: Nomikos M
Year: 2011
Journal: J Cell Sci
Title: Phospholipase Cζ binding to PtdIns(4,5)P2 requires the XY-linker region.
Volume: 124
Issue: Pt 15
Pages: 2582-90
Publication
First Author: Boswell KL
Year: 2012
Journal: J Cell Biol
Title: Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion.
Volume: 197
Issue: 2
Pages: 301-12
Publication
First Author: Yue H
Year: 2012
Journal: Biochim Biophys Acta
Title: Thymidine phosphorylase inhibits vascular smooth muscle cell proliferation via upregulation of STAT3.
Volume: 1823
Issue: 8
Pages: 1316-23
Publication
First Author: Rahman S
Year: 2013
Journal: Endocrinology
Title: Inducible brown adipose tissue, or beige fat, is anabolic for the skeleton.
Volume: 154
Issue: 8
Pages: 2687-701
Publication
First Author: Bodanovsky A
Year: 2014
Journal: Biochim Biophys Acta
Title: Halofuginone improves muscle-cell survival in muscular dystrophies.
Volume: 1843
Issue: 7
Pages: 1339-47
Publication  
First Author: Sladojevic N
Year: 2014
Journal: Neurobiol Dis
Title: Inhibition of junctional adhesion molecule-A/LFA interaction attenuates leukocyte trafficking and inflammation in brain ischemia/reperfusion injury.
Volume: 67
Pages: 57-70
Publication
First Author: Ramakrishnan NA
Year: 2014
Journal: J Biol Chem
Title: Calcium regulates molecular interactions of otoferlin with soluble NSF attachment protein receptor (SNARE) proteins required for hair cell exocytosis.
Volume: 289
Issue: 13
Pages: 8750-66
Publication
First Author: Mays CE
Year: 2014
Journal: FEBS J
Title: Endoproteolytic processing of the mammalian prion glycoprotein family.
Volume: 281
Issue: 3
Pages: 862-76
Publication  
First Author: Munfus DL
Year: 2007
Journal: BMC Biol
Title: A conserved gene family encodes transmembrane proteins with fibronectin, immunoglobulin and leucine-rich repeat domains (FIGLER).
Volume: 5
Pages: 36
Publication
First Author: Hussain NK
Year: 1999
Journal: J Biol Chem
Title: Splice variants of intersectin are components of the endocytic machinery in neurons and nonneuronal cells.
Volume: 274
Issue: 22
Pages: 15671-7
Publication  
First Author: Meabon JS
Year: 2016
Journal: Mol Cell Neurosci
Title: Intracellular LINGO-1 negatively regulates Trk neurotrophin receptor signaling.
Volume: 70
Pages: 1-10
Publication
First Author: Chen X
Year: 2014
Journal: Am J Respir Cell Mol Biol
Title: A soluble adenylyl cyclase form targets to axonemes and rescues beat regulation in soluble adenylyl cyclase knockout mice.
Volume: 51
Issue: 6
Pages: 750-60
Publication
First Author: Lau A
Year: 2015
Journal: EMBO Mol Med
Title: Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation.
Volume: 7
Issue: 3
Pages: 339-56
Publication
First Author: Zanotti S
Year: 2015
Journal: J Cell Physiol
Title: Activation of Nfatc2 in osteoblasts causes osteopenia.
Volume: 230
Issue: 7
Pages: 1689-95
Publication  
First Author: Chuang JC
Year: 2017
Journal: Biochem Pharmacol
Title: Quantitation of the rates of hepatic and intestinal cholesterol synthesis in lysosomal acid lipase-deficient mice before and during treatment with ezetimibe.
Volume: 135
Pages: 116-125
Publication
First Author: Yang M
Year: 2017
Journal: Sci Rep
Title: Skin transcriptome reveals the intrinsic molecular mechanisms underlying hair follicle cycling in Cashmere goats under natural and shortened photoperiod conditions.
Volume: 7
Issue: 1
Pages: 13502
Publication
First Author: Bruinsma S
Year: 2018
Journal: J Biol Chem
Title: Small molecules that inhibit the late stage of Munc13-4-dependent secretory granule exocytosis in mast cells.
Volume: 293
Issue: 21
Pages: 8217-8229
Publication
First Author: Nakazono A
Year: 2018
Journal: J Biol Chem
Title: Pharmacological induction of heat shock proteins ameliorates toxicity of mutant PKCγ in spinocerebellar ataxia type 14.
Volume: 293
Issue: 38
Pages: 14758-14774
Publication
First Author: Lin YL
Year: 2018
Journal: Sci Rep
Title: A CpG-adjuvanted intranasal enterovirus 71 vaccine elicits mucosal and systemic immune responses and protects human SCARB2-transgenic mice against lethal challenge.
Volume: 8
Issue: 1
Pages: 10713
Publication
First Author: Zarantonello A
Year: 2020
Journal: J Immunol
Title: An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase.
Volume: 205
Issue: 6
Pages: 1678-1694
Publication
First Author: Du TT
Year: 2015
Journal: Autophagy
Title: GBA deficiency promotes SNCA/α-synuclein accumulation through autophagic inhibition by inactivated PPP2A.
Volume: 11
Issue: 10
Pages: 1803-20
Publication
First Author: Zizza P
Year: 2012
Journal: J Biol Chem
Title: Phospholipase A2IVα regulates phagocytosis independent of its enzymatic activity.
Volume: 287
Issue: 20
Pages: 16849-59
Publication
First Author: Koren-Gluzer M
Year: 2013
Journal: Atherosclerosis
Title: Paraoxonase1 (PON1) reduces insulin resistance in mice fed a high-fat diet, and promotes GLUT4 overexpression in myocytes, via the IRS-1/Akt pathway.
Volume: 229
Issue: 1
Pages: 71-8
Publication
First Author: Chang L
Year: 2020
Journal: Nat Commun
Title: Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.
Volume: 11
Issue: 1
Pages: 3464
Publication
First Author: Holt O
Year: 2008
Journal: Traffic
Title: Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse.
Volume: 9
Issue: 4
Pages: 446-57
Protein
Organism: Mus musculus/domesticus
Length: 454  
Fragment?: false
Publication  
First Author: Gorin MA
Year: 2009
Journal: Mol Cancer
Title: Protein kinase C epsilon: an oncogene and emerging tumor biomarker.
Volume: 8
Pages: 9
Publication
First Author: Basu A
Year: 2007
Journal: Cell Signal
Title: Protein kinase Cepsilon makes the life and death decision.
Volume: 19
Issue: 8
Pages: 1633-42
Publication
First Author: Pang ZP
Year: 2010
Journal: Curr Opin Cell Biol
Title: Cell biology of Ca2+-triggered exocytosis.
Volume: 22
Issue: 4
Pages: 496-505
Publication
First Author: Chen D
Year: 2004
Journal: Mol Cell Biol
Title: p50alpha/p55alpha phosphoinositide 3-kinase knockout mice exhibit enhanced insulin sensitivity.
Volume: 24
Issue: 1
Pages: 320-9
Publication
First Author: Yu J
Year: 1998
Journal: Mol Cell Biol
Title: Regulation of the p85/p110 phosphatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit.
Volume: 18
Issue: 3
Pages: 1379-87
Protein Domain
Type: Domain
Description: Phosphoinositide 3-kinases (PI3Ks) are essential for cell growth, migration, and survival. Class IA PI3Ks are heterodimers of a p110 catalytic (C) subunit and a p85-related regulatory (R) subunit []. p110 is composed of an adaptor-binding domain, a Ras-binding domain, a C2 domain, a helical domain, and a kinase domain. p85 is composed of an SH3 domain, a RhoGap domain, a N-terminal SH2 (nSH2) domain, a inter SH2 (iSH2) domain, and C-terminal (cSH2) domain. There are two inhibitory interactions between p110alpha and p85 of P13K: 1) p85 nSH2 domain with the C2, helical, and kinase domains of p110alpha and 2) p85 iSH2 domain with C2 domain of p110alpha. There are three inhibitory interactions between p110beta and p85 of P13K: 1) p85 nSH2 domain with the C2, helical, and kinase domains of p110beta, 2) p85 iSH2 domain with C2 domain of p110beta, and 3) p85 cSH2 domain with the kinase domain of p110beta []. p110beta is oncogenic as a wild type protein while p110alpha lacks this ability. One explanation is that the regulation of p110beta by p85 is unique because of the addition of inhibitory contacts from the cSH2 domain and the loss of contacts in the iSH2 domain []. In general SH2 domains are involved in signal transduction. They typically bind pTyr-containing ligands via two surface pockets, a pTyr and hydrophobic binding pocket, allowing proteins with SH2 domains to localize to tyrosine phosphorylated sites [].In mammals, there are multiple class IA PI3K regulatory and catalytic subunits. There are three genes that encode at least five different regulatory subunit proteins (p85alpha, p55alpha, p50alpha, p85beta, and p55gamma) and three genes encoding three catalytic subunits (p110alpha, p110beta, and p110delta) [].Among all the class IA PI3K combinations, p85alpha/p110alpha heterodimer has been the most intensely investigated. p110alpha has been shown to be stabilized and inhibited by dimerization with p85alpha []. Moreover, p85alpha (also called PIK3R1) has functions independent of its PI3K regulatory role. It can independently stimulate signalling pathways involved in cytoskeletal rearrangements []. PIK3R1 has been shown to play an important role in insulin signalling [].This entry represents the iSH2 domain found in PIK3R1.
Publication
First Author: Lessard J
Year: 2007
Journal: Neuron
Title: An essential switch in subunit composition of a chromatin remodeling complex during neural development.
Volume: 55
Issue: 2
Pages: 201-15
Publication
First Author: Kaeser MD
Year: 2008
Journal: J Biol Chem
Title: BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells.
Volume: 283
Issue: 47
Pages: 32254-63
Publication
First Author: Olave I
Year: 2002
Journal: Genes Dev
Title: Identification of a polymorphic, neuron-specific chromatin remodeling complex.
Volume: 16
Issue: 19
Pages: 2509-17
Publication
First Author: Wu JI
Year: 2007
Journal: Neuron
Title: Regulation of dendritic development by neuron-specific chromatin remodeling complexes.
Volume: 56
Issue: 1
Pages: 94-108
Publication
First Author: Nakagawa T
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.
Volume: 94
Issue: 18
Pages: 9654-9
Publication  
First Author: Hou J
Year: 2007
Journal: BMC Dev Biol
Title: A systematic screen for genes expressed in definitive endoderm by Serial Analysis of Gene Expression (SAGE).
Volume: 7
Pages: 92
Publication  
First Author: Liu CF
Year: 2018
Journal: Development
Title: SOX9 is dispensable for the initiation of epigenetic remodeling and the activation of marker genes at the onset of chondrogenesis.
Volume: 145
Issue: 14
Publication
First Author: Chi TH
Year: 2002
Journal: Nature
Title: Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes.
Volume: 418
Issue: 6894
Pages: 195-9
Publication
First Author: Paces-Fessy M
Year: 2012
Journal: Hum Mol Genet
Title: Hnf1b and Pax2 cooperate to control different pathways in kidney and ureter morphogenesis.
Volume: 21
Issue: 14
Pages: 3143-55
Publication
First Author: Hägglund AC
Year: 2017
Journal: Dis Model Mech
Title: A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of Tsc1 disrupts ciliary body and iris development.
Volume: 10
Issue: 3
Pages: 245-257
Publication
First Author: Nilsson D
Year: 2019
Journal: Physiol Rep
Title: Foxc2 is essential for podocyte function.
Volume: 7
Issue: 9
Pages: e14083
Publication
First Author: Bachmann C
Year: 2016
Journal: PLoS Genet
Title: mSWI/SNF (BAF) Complexes Are Indispensable for the Neurogenesis and Development of Embryonic Olfactory Epithelium.
Volume: 12
Issue: 9
Pages: e1006274
Publication
First Author: Kong P
Year: 2014
Journal: Hum Mol Genet
Title: Tbx1 is required autonomously for cell survival and fate in the pharyngeal core mesoderm to form the muscles of mastication.
Volume: 23
Issue: 16
Pages: 4215-31
Publication
First Author: Yan S
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: CHD7 regulates cardiovascular development through ATP-dependent and -independent activities.
Volume: 117
Issue: 46
Pages: 28847-28858
Publication  
First Author: Sokpor G
Year: 2021
Journal: Front Mol Neurosci
Title: Loss of BAF Complex in Developing Cortex Perturbs Radial Neuronal Migration in a WNT Signaling-Dependent Manner.
Volume: 14
Pages: 687581
Publication
First Author: Tuoc T
Year: 2017
Journal: Mol Neurobiol
Title: Ablation of BAF170 in Developing and Postnatal Dentate Gyrus Affects Neural Stem Cell Proliferation, Differentiation, and Learning.
Volume: 54
Issue: 6
Pages: 4618-4635
Publication
First Author: Pfister S
Year: 2011
Journal: Int J Dev Biol
Title: Sox17-dependent gene expression and early heart and gut development in Sox17-deficient mouse embryos.
Volume: 55
Issue: 1
Pages: 45-58
Publication    
First Author: Honda K
Year: 2017
Journal: Elife
Title: Molecular architecture underlying fluid absorption by the developing inner ear.
Volume: 6
Publication
First Author: Paul MH
Year: 2014
Journal: Cell Mol Life Sci
Title: Cardiac outflow tract development relies on the complex function of Sox4 and Sox11 in multiple cell types.
Volume: 71
Issue: 15
Pages: 2931-45
Publication
First Author: Klochendler-Yeivin A
Year: 2000
Journal: EMBO Rep
Title: The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression.
Volume: 1
Issue: 6
Pages: 500-6
Publication
First Author: Garcia TX
Year: 2014
Journal: Development
Title: RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche.
Volume: 141
Issue: 23
Pages: 4468-78
Publication  
First Author: Almubarak A
Year: 2024
Journal: Development
Title: FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton.
Volume: 151
Issue: 16
Publication
First Author: Dykhuizen EC
Year: 2013
Journal: Nature
Title: BAF complexes facilitate decatenation of DNA by topoisomerase IIα.
Volume: 497
Issue: 7451
Pages: 624-7
Publication  
First Author: Wang A
Year: 2021
Journal: Development
Title: An epigenetic circuit controls neurogenic programs during neocortex development.
Volume: 148
Issue: 22
Publication
First Author: Staahl BT
Year: 2013
Journal: J Neurosci
Title: Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways.
Volume: 33
Issue: 25
Pages: 10348-61
Publication
First Author: Válka I
Year: 1985
Journal: Planta Med
Title: Separation and Quantification of Some Alkaloids from Fumaria parviflora by Capillary Isotachophoresis1.
Volume: 51
Issue: 4
Pages: 319-22
Publication
First Author: Kakarougkas A
Year: 2014
Journal: Mol Cell
Title: Requirement for PBAF in transcriptional repression and repair at DNA breaks in actively transcribed regions of chromatin.
Volume: 55
Issue: 5
Pages: 723-32
Publication
First Author: de la Serna IL
Year: 2001
Journal: Nat Genet
Title: Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation.
Volume: 27
Issue: 2
Pages: 187-90
Publication
First Author: Park JH
Year: 2006
Journal: EMBO J
Title: Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction.
Volume: 25
Issue: 17
Pages: 3986-97
Publication
First Author: Davisson MT
Year: 2001
Journal: Genomics
Title: Evolutionary breakpoints on human chromosome 21.
Volume: 78
Issue: 1-2
Pages: 99-106
Publication  
First Author: Chal J
Year: 2018
Journal: Development
Title: Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro.
Volume: 145
Issue: 6
Publication  
First Author: Xue L
Year: 2013
Journal: BMC Genomics
Title: Global expression profiling reveals genetic programs underlying the developmental divergence between mouse and human embryogenesis.
Volume: 14
Pages: 568
Publication
First Author: Pang ZP
Year: 2011
Journal: Neuron
Title: Doc2 supports spontaneous synaptic transmission by a Ca(2+)-independent mechanism.
Volume: 70
Issue: 2
Pages: 244-51
Publication
First Author: Yasuda T
Year: 2010
Journal: Cell Metab
Title: Rim2alpha determines docking and priming states in insulin granule exocytosis.
Volume: 12
Issue: 2
Pages: 117-29
Publication
First Author: Mecklenbräuker I
Year: 2002
Journal: Nature
Title: Protein kinase Cdelta controls self-antigen-induced B-cell tolerance.
Volume: 416
Issue: 6883
Pages: 860-5
Publication
First Author: Hirano M
Year: 2005
Journal: J Immunol
Title: Mannan-binding protein blocks the activation of metalloproteases meprin alpha and beta.
Volume: 175
Issue: 5
Pages: 3177-85
Protein
Organism: Mus musculus/domesticus
Length: 597  
Fragment?: false
Publication
First Author: Maximov A
Year: 2007
Journal: J Cell Biol
Title: Synaptotagmin-12, a synaptic vesicle phosphoprotein that modulates spontaneous neurotransmitter release.
Volume: 176
Issue: 1
Pages: 113-24
Publication
First Author: Kaeser-Woo YJ
Year: 2013
Journal: J Neurosci
Title: Synaptotagmin-12 phosphorylation by cAMP-dependent protein kinase is essential for hippocampal mossy fiber LTP.
Volume: 33
Issue: 23
Pages: 9769-80
Publication
First Author: Watanabe G
Year: 1996
Journal: Science
Title: Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase Rho.
Volume: 271
Issue: 5249
Pages: 645-8
Protein
Organism: Mus musculus/domesticus
Length: 89  
Fragment?: true
Publication
First Author: Zeng M
Year: 2016
Journal: Cell
Title: Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity.
Volume: 166
Issue: 5
Pages: 1163-1175.e12
Protein
Organism: Mus musculus/domesticus
Length: 43  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 191  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 59  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 114  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 91  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 122  
Fragment?: false
Publication
First Author: Ruzicka FJ
Year: 2007
Journal: Biochim Biophys Acta
Title: Glutamate 2,3-aminomutase: a new member of the radical SAM superfamily of enzymes.
Volume: 1774
Issue: 2
Pages: 286-96
Publication
First Author: Vander Byl C
Year: 2000
Journal: J Bacteriol
Title: Sequence of the genome of Salmonella bacteriophage P22.
Volume: 182
Issue: 22
Pages: 6472-81
Publication
First Author: Rumbaugh G
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: SynGAP regulates synaptic strength and mitogen-activated protein kinases in cultured neurons.
Volume: 103
Issue: 12
Pages: 4344-51
Publication
First Author: Yang SN
Year: 2004
Journal: Neurosci Lett
Title: Impaired SynGAP expression and long-term spatial learning and memory in hippocampal CA1 area from rats previously exposed to perinatal hypoxia-induced insults: beneficial effects of A68930.
Volume: 371
Issue: 1
Pages: 73-8
Publication
First Author: Scheffzek K
Year: 1996
Journal: Nature
Title: Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras.
Volume: 384
Issue: 6609
Pages: 591-6
Publication
First Author: Zhang Y
Year: 1993
Journal: J Biol Chem
Title: Purification, characterization, and cellular localization of the 100-kDa human placental GTPase-activating protein.
Volume: 268
Issue: 25
Pages: 18875-81
Publication
First Author: Giglione C
Year: 2001
Journal: Eur J Biochem
Title: Differential actions of p60c-Src and Lck kinases on the Ras regulators p120-GAP and GDP/GTP exchange factor CDC25Mm.
Volume: 268
Issue: 11
Pages: 3275-83
Publication
First Author: Pamonsinlapatham P
Year: 2009
Journal: Biochimie
Title: p120-Ras GTPase activating protein (RasGAP): a multi-interacting protein in downstream signaling.
Volume: 91
Issue: 3
Pages: 320-8
Publication
First Author: Dai H
Year: 2004
Journal: Nat Struct Mol Biol
Title: Structural basis for the evolutionary inactivation of Ca2+ binding to synaptotagmin 4.
Volume: 11
Issue: 9
Pages: 844-9
Publication
First Author: von Poser C
Year: 1997
Journal: J Biol Chem
Title: The evolutionary pressure to inactivate. A subclass of synaptotagmins with an amino acid substitution that abolishes Ca2+ binding.
Volume: 272
Issue: 22
Pages: 14314-9
Publication
First Author: Tong Q
Year: 2011
Journal: Neuron
Title: Synaptotagmin 4: a new antiobesity target?
Volume: 69
Issue: 3
Pages: 401-3
Publication
First Author: Ferguson GD
Year: 2001
Journal: Mol Neurobiol
Title: Synaptotagmin IV: biochemistry, genetics, behavior, and possible links to human psychiatric disease.
Volume: 23
Issue: 2-3
Pages: 173-85
Publication
First Author: Littleton JT
Year: 1999
Journal: Nature
Title: Synaptic function modulated by changes in the ratio of synaptotagmin I and IV.
Volume: 400
Issue: 6746
Pages: 757-60