Type |
Details |
Score |
Publication |
First Author: |
Markovics A |
Year: |
2020 |
Journal: |
Arthritis Res Ther |
Title: |
Regulation of autoimmune arthritis by the SHP-1 tyrosine phosphatase. |
Volume: |
22 |
Issue: |
1 |
Pages: |
160 |
|
•
•
•
•
•
|
Publication |
First Author: |
Portillo JC |
Year: |
2022 |
Journal: |
Diabetologia |
Title: |
Disruption of retinal inflammation and the development of diabetic retinopathy in mice by a CD40-derived peptide or mutation of CD40 in Müller cells. |
Volume: |
65 |
Issue: |
12 |
Pages: |
2157-2171 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
659
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
499
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
537
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
524
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
659
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
482
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
499
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
655
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
483
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
524
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
625
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
619
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
622
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
618
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
164
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Kutz WE |
Year: |
2005 |
Journal: |
Mol Cell Biol |
Title: |
WISP3, the gene responsible for the human skeletal disease progressive pseudorheumatoid dysplasia, is not essential for skeletal function in mice. |
Volume: |
25 |
Issue: |
1 |
Pages: |
414-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen R |
Year: |
2006 |
Journal: |
Mol Cell Biol |
Title: |
Association between SAP and FynT: Inducible SH3 domain-mediated interaction controlled by engagement of the SLAM receptor. |
Volume: |
26 |
Issue: |
15 |
Pages: |
5559-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schäfer I |
Year: |
2016 |
Journal: |
J Cell Sci |
Title: |
MOBP levels are regulated by Fyn kinase and affect the morphological differentiation of oligodendrocytes. |
Volume: |
129 |
Issue: |
5 |
Pages: |
930-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nishio H |
Year: |
2005 |
Journal: |
Scand J Immunol |
Title: |
Evidence for involvement of p59fyn in fasting-induced thymic involution. |
Volume: |
62 |
Issue: |
2 |
Pages: |
103-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takahashi T |
Year: |
1997 |
Journal: |
J Immunol |
Title: |
Suppression of autoimmune disease and of massive lymphadenopathy in MRL/Mp-lpr/lpr mice lacking tyrosine kinase Fyn (p59fyn). |
Volume: |
159 |
Issue: |
5 |
Pages: |
2532-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
McGough NN |
Year: |
2004 |
Journal: |
J Neurosci |
Title: |
RACK1 and brain-derived neurotrophic factor: a homeostatic pathway that regulates alcohol addiction. |
Volume: |
24 |
Issue: |
46 |
Pages: |
10542-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wallace VA |
Year: |
1994 |
|
Title: |
T-Cell development in CD4, CD8, and p56(lck) Gene-Targeted mice. |
|
|
Pages: |
67-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Minami SS |
Year: |
2012 |
Journal: |
Neurobiol Aging |
Title: |
Fyn knock-down increases Aβ, decreases phospho-tau, and worsens spatial learning in 3×Tg-AD mice. |
Volume: |
33 |
Issue: |
4 |
Pages: |
825.e15-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Davidson D |
Year: |
2004 |
Journal: |
Immunity |
Title: |
Genetic evidence linking SAP, the X-linked lymphoproliferative gene product, to Src-related kinase FynT in T(H)2 cytokine regulation. |
Volume: |
21 |
Issue: |
5 |
Pages: |
707-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li C |
Year: |
2017 |
Journal: |
EMBO J |
Title: |
Somatodendritic accumulation of Tau in Alzheimer's disease is promoted by Fyn-mediated local protein translation. |
Volume: |
36 |
Issue: |
21 |
Pages: |
3120-3138 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cannons JL |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation. |
Volume: |
185 |
Issue: |
5 |
Pages: |
2819-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Krebs B |
Year: |
2007 |
Journal: |
J Neurochem |
Title: |
Cellular prion protein modulates the intracellular calcium response to hydrogen peroxide. |
Volume: |
100 |
Issue: |
2 |
Pages: |
358-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Briner A |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
Fyn Kinase Controls Tau Aggregation In Vivo. |
Volume: |
32 |
Issue: |
7 |
Pages: |
108045 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xia D |
Year: |
2015 |
Journal: |
Biochim Biophys Acta |
Title: |
Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spines. |
Volume: |
1852 |
Issue: |
5 |
Pages: |
913-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tse MC |
Year: |
2013 |
Journal: |
Mol Cell Biol |
Title: |
Fyn regulates adipogenesis by promoting PIKE-A/STAT5a interaction. |
Volume: |
33 |
Issue: |
9 |
Pages: |
1797-808 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ko HM |
Year: |
2018 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Tyrosine kinase Fyn regulates iNOS expression in LPS-stimulated astrocytes via modulation of ERK phosphorylation. |
Volume: |
495 |
Issue: |
1 |
Pages: |
1214-1220 |
|
•
•
•
•
•
|
Publication |
First Author: |
Paranjape A |
Year: |
2020 |
Journal: |
Cell Immunol |
Title: |
The Fyn-Stat5 cascade is required for Fcγ receptor-mediated mast cell function. |
Volume: |
356 |
|
Pages: |
104134 |
|
•
•
•
•
•
|
Publication |
First Author: |
Anidi IU |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
CD36 and Fyn kinase mediate malaria-induced lung endothelial barrier dysfunction in mice infected with Plasmodium berghei. |
Volume: |
8 |
Issue: |
8 |
Pages: |
e71010 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kovalovsky D |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
PLZF induces the spontaneous acquisition of memory/effector functions in T cells independently of NKT cell-related signals. |
Volume: |
184 |
Issue: |
12 |
Pages: |
6746-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Märklin M |
Year: |
2020 |
Journal: |
Front Immunol |
Title: |
Genetic Loss of LCK Kinase Leads to Acceleration of Chronic Lymphocytic Leukemia. |
Volume: |
11 |
|
Pages: |
1995 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chiang YJ |
Year: |
2015 |
Journal: |
Int Immunol |
Title: |
Regulation of T cell development by c-Cbl: essential role of Lck. |
Volume: |
27 |
Issue: |
5 |
Pages: |
245-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee WH |
Year: |
2003 |
Journal: |
Eur J Immunol |
Title: |
Development of T cells expressing an altered TCR complex. |
Volume: |
33 |
Issue: |
10 |
Pages: |
2696-705 |
|
•
•
•
•
•
|
Publication |
First Author: |
de la Roche M |
Year: |
2013 |
Journal: |
Science |
Title: |
Hedgehog signaling controls T cell killing at the immunological synapse. |
Volume: |
342 |
Issue: |
6163 |
Pages: |
1247-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mombaerts P |
Year: |
1994 |
Journal: |
Immunity |
Title: |
An activated lck transgene promotes thymocyte development in RAG-1 mutant mice. |
Volume: |
1 |
Issue: |
4 |
Pages: |
261-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fujikake K |
Year: |
2018 |
Journal: |
J Neurosci |
Title: |
Detachment of Chain-Forming Neuroblasts by Fyn-Mediated Control of cell-cell Adhesion in the Postnatal Brain. |
Volume: |
38 |
Issue: |
19 |
Pages: |
4598-4609 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lo WL |
Year: |
2018 |
Journal: |
Nat Immunol |
Title: |
Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT. |
Volume: |
19 |
Issue: |
7 |
Pages: |
733-741 |
|
•
•
•
•
•
|
Publication |
First Author: |
Paster W |
Year: |
2015 |
Journal: |
EMBO J |
Title: |
A THEMIS:SHP1 complex promotes T-cell survival. |
Volume: |
34 |
Issue: |
3 |
Pages: |
393-409 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nishida K |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
Gab2, via PI-3K, regulates ARF1 in FcεRI-mediated granule translocation and mast cell degranulation. |
Volume: |
187 |
Issue: |
2 |
Pages: |
932-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miyakawa T |
Year: |
1996 |
Journal: |
Brain Res Mol Brain Res |
Title: |
Radial maze performance, open-field and elevated plus-maze behaviors in Fyn-kinase deficient mice: further evidence for increased fearfulness. |
Volume: |
37 |
Issue: |
1-2 |
Pages: |
145-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takizawa H |
Year: |
2010 |
Journal: |
J Clin Invest |
Title: |
Lnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo. |
Volume: |
120 |
Issue: |
1 |
Pages: |
179-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miyakawa T |
Year: |
1997 |
Journal: |
Science |
Title: |
Fyn-kinase as a determinant of ethanol sensitivity: relation to NMDA-receptor function. |
Volume: |
278 |
Issue: |
5338 |
Pages: |
698-701 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matsuki N |
Year: |
2003 |
Journal: |
J Immunol |
Title: |
Genetic dissection of V alpha 14J alpha 18 natural T cell number and function in autoimmune-prone mice. |
Volume: |
170 |
Issue: |
11 |
Pages: |
5429-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Menzel V |
Year: |
2022 |
Journal: |
Eur J Pharm Sci |
Title: |
Fyn-kinase and caveolin-1 in the alveolar epithelial junctional adherence complex contribute to the early stages of pulmonary fibrosis. |
Volume: |
175 |
|
Pages: |
106236 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roberson ED |
Year: |
2011 |
Journal: |
J Neurosci |
Title: |
Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease. |
Volume: |
31 |
Issue: |
2 |
Pages: |
700-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Griff IC |
Year: |
1995 |
Journal: |
Cell |
Title: |
The genetic basis for specific anosmia to isovaleric acid in the mouse. |
Volume: |
83 |
Issue: |
3 |
Pages: |
407-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Blas-Rus N |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
Aurora A drives early signalling and vesicle dynamics during T-cell activation. |
Volume: |
7 |
|
Pages: |
11389 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liang J |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Tespa1 regulates T cell receptor-induced calcium signals by recruiting inositol 1,4,5-trisphosphate receptors. |
Volume: |
8 |
|
Pages: |
15732 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ninchoji T |
Year: |
2021 |
Journal: |
Elife |
Title: |
eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin. |
Volume: |
10 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Yamada E |
Year: |
2010 |
Journal: |
Cell Metab |
Title: |
Fyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1. |
Volume: |
11 |
Issue: |
2 |
Pages: |
113-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chesarino NM |
Year: |
2014 |
Journal: |
J Biol Chem |
Title: |
Phosphorylation of the antiviral protein interferon-inducible transmembrane protein 3 (IFITM3) dually regulates its endocytosis and ubiquitination. |
Volume: |
289 |
Issue: |
17 |
Pages: |
11986-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Olivera A |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
IgE-dependent activation of sphingosine kinases 1 and 2 and secretion of sphingosine 1-phosphate requires Fyn kinase and contributes to mast cell responses. |
Volume: |
281 |
Issue: |
5 |
Pages: |
2515-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kozak CA |
Year: |
1991 |
Journal: |
Genomics |
Title: |
Genetic mapping of the gene for a novel tyrosine kinase, Blk, to mouse chromosome 14. |
Volume: |
9 |
Issue: |
4 |
Pages: |
762-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morahan G |
Year: |
1993 |
Journal: |
Genomics |
Title: |
Localization of the mouse Na+/H+ exchanger gene on distal chromosome 4. |
Volume: |
15 |
Issue: |
1 |
Pages: |
231-2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ko BC |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Fyn and p38 signaling are both required for maximal hypertonic activation of the osmotic response element-binding protein/tonicity-responsive enhancer-binding protein (OREBP/TonEBP). |
Volume: |
277 |
Issue: |
48 |
Pages: |
46085-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nunez-Cruz S |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Differential requirement for the SAP-Fyn interaction during NK T cell development and function. |
Volume: |
181 |
Issue: |
4 |
Pages: |
2311-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nazarov-Stoica C |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
CD28 signaling in T regulatory precursors requires p56lck and rafts integrity to stabilize the Foxp3 message. |
Volume: |
182 |
Issue: |
1 |
Pages: |
102-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang PS |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
Protein-tyrosine phosphatase alpha acts as an upstream regulator of Fyn signaling to promote oligodendrocyte differentiation and myelination. |
Volume: |
284 |
Issue: |
48 |
Pages: |
33692-702 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barbu EA |
Year: |
2010 |
Journal: |
J Biol Chem |
Title: |
The limited contribution of Fyn and Gab2 to the high affinity IgE receptor signaling in mast cells. |
Volume: |
285 |
Issue: |
21 |
Pages: |
15761-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shirata N |
Year: |
2017 |
Journal: |
J Am Soc Nephrol |
Title: |
Glomerulosclerosis Induced by Deficiency of Membrane-Associated Guanylate Kinase Inverted 2 in Kidney Podocytes. |
Volume: |
28 |
Issue: |
9 |
Pages: |
2654-2669 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhumabekov T |
Year: |
1995 |
Journal: |
J Immunol Methods |
Title: |
Improved version of a human CD2 minigene based vector for T cell-specific expression in transgenic mice. |
Volume: |
185 |
Issue: |
1 |
Pages: |
133-40 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
535
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
703
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
220
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
621
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
631
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
538
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
536
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
722
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
593
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
595
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
60
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
159
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
597
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
368
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
393
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
595
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
123
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
194
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
220
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
409
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
191
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
116
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
504
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
46
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
374
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
969
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
97
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
595
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
703
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1157
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
722
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
341
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
172
 |
Fragment?: |
false |
|
•
•
•
•
•
|