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Search results 7801 to 7900 out of 8814 for Clock

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Type Details Score
Publication
30713103 | J:286531
First Author: Zhang Z
Year: 2019
Journal: Curr Biol
Title: Superior Colliculus GABAergic Neurons Are Essential for Acute Dark Induction of Wakefulness in Mice.
Volume: 29
Issue: 4
Pages: 637-644.e3
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Publication
34502541 | J:313818
 
First Author: Duffield GE
Year: 2021
Journal: Int J Mol Sci
Title: Targeted Disruption of the Inhibitor of DNA Binding 4 (Id4) Gene Alters Photic Entrainment of the Circadian Clock.
Volume: 22
Issue: 17
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Publication
28954569 | J:268883
First Author: Hsu YA
Year: 2017
Journal: J Biol Rhythms
Title: The Dorsal Medial Habenula Minimally Impacts Circadian Regulation of Locomotor Activity and Sleep.
Volume: 32
Issue: 5
Pages: 444-455
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Publication
12542655 | J:97141
First Author: Cutler DJ
Year: 2003
Journal: Eur J Neurosci
Title: The mouse VPAC2 receptor confers suprachiasmatic nuclei cellular rhythmicity and responsiveness to vasoactive intestinal polypeptide in vitro.
Volume: 17
Issue: 2
Pages: 197-204
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Publication
21256124 | J:170604
First Author: Zhang Z
Year: 2011
Journal: Dev Biol
Title: The microRNA-processing enzyme Dicer is dispensable for somite segmentation but essential for limb bud positioning.
Volume: 351
Issue: 2
Pages: 254-65
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Publication
21178124 | J:170374
First Author: Hannibal J
Year: 2011
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Temporal phasing of locomotor activity, heart rate rhythmicity, and core body temperature is disrupted in VIP receptor 2-deficient mice.
Volume: 300
Issue: 3
Pages: R519-30
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Publication
33347504 | J:299480
First Author: Murakami M
Year: 2020
Journal: PLoS One
Title: Decreased cardiac pacemaking and attenuated β-adrenergic response in TRIC-A knockout mice.
Volume: 15
Issue: 12
Pages: e0244254
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Publication
26762333 | J:232646
First Author: Rakshit K
Year: 2016
Journal: Diabetologia
Title: Bmal1 is required for beta cell compensatory expansion, survival and metabolic adaptation to diet-induced obesity in mice.
Volume: 59
Issue: 4
Pages: 734-43
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Publication
27486508 | J:240342
 
First Author: Harfmann BD
Year: 2016
Journal: Skelet Muscle
Title: Muscle-specific loss of Bmal1 leads to disrupted tissue glucose metabolism and systemic glucose homeostasis.
Volume: 6
Pages: 12
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Publication
36334897 | J:341739
 
First Author: Altaha B
Year: 2022
Journal: Mol Metab
Title: Genetic and environmental circadian disruption induce weight gain through changes in the gut microbiome.
Volume: 66
Pages: 101628
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Publication
31560728 | J:280030
First Author: Chang ML
Year: 2019
Journal: PLoS One
Title: Regulatory interaction between the ZPBP2-ORMDL3/Zpbp2-Ormdl3 region and the circadian clock.
Volume: 14
Issue: 9
Pages: e0223212
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Publication
28260693 | J:255354
First Author: Siddiqui S
Year: 2017
Journal: Aging (Albany NY)
Title: Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption.
Volume: 9
Issue: 3
Pages: 706-740
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Publication
36426781 | J:348403
First Author: Miller AM
Year: 2022
Journal: J Neuroendocrinol
Title: Glucocorticoid regulation of diurnal spine plasticity in the murine ventromedial prefrontal cortex.
Volume: 34
Issue: 12
Pages: e13212
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Publication
38565587 | J:361370
First Author: Ogasawara J
Year: 2024
Journal: Sci Rep
Title: Lengthened circadian rhythms in mice with self-controlled ambient light intensity.
Volume: 14
Issue: 1
Pages: 7778
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Publication
24023810 | J:207563
First Author: Mathew D
Year: 2013
Journal: PLoS One
Title: Ablation of the ID2 gene results in altered circadian feeding behavior, and sex-specific enhancement of insulin sensitivity and elevated glucose uptake in skeletal muscle and brown adipose tissue.
Volume: 8
Issue: 9
Pages: e73064
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Publication
27992553 | J:253189
First Author: Kofuji P
Year: 2016
Journal: PLoS One
Title: Intrinsically Photosensitive Retinal Ganglion Cells (ipRGCs) Are Necessary for Light Entrainment of Peripheral Clocks.
Volume: 11
Issue: 12
Pages: e0168651
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Publication
25695720 | J:221903
First Author: Mereness AL
Year: 2015
Journal: Biol Reprod
Title: Developmental programming by androgen affects the circadian timing system in female mice.
Volume: 92
Issue: 4
Pages: 88
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Publication
33391484 | J:340221
First Author: Lin Y
Year: 2021
Journal: Theranostics
Title: Oscillating lncRNA Platr4 regulates NLRP3 inflammasome to ameliorate nonalcoholic steatohepatitis in mice.
Volume: 11
Issue: 1
Pages: 426-444
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Publication
10077319 | J:52956
First Author: Lupi D
Year: 1999
Journal: Neuroscience
Title: Transgenic ablation of rod photoreceptors alters the circadian phenotype of mice.
Volume: 89
Issue: 2
Pages: 363-74
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Publication
31915376 | J:293851
First Author: Yoshioka-Kobayashi K
Year: 2020
Journal: Nature
Title: Coupling delay controls synchronized oscillation in the segmentation clock.
Volume: 580
Issue: 7801
Pages: 119-123
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Publication
35743288 | J:336974
 
First Author: Fernández-Ortiz M
Year: 2022
Journal: Int J Mol Sci
Title: Age and Chronodisruption in Mouse Heart: Effect of the NLRP3 Inflammasome and Melatonin Therapy.
Volume: 23
Issue: 12
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Publication
34085306 | J:336556
First Author: Zhang C
Year: 2021
Journal: J Pineal Res
Title: Impact of endogenous melatonin on rhythmic behaviors, reproduction, and survival revealed in melatonin-proficient C57BL/6J congenic mice.
Volume: 71
Issue: 2
Pages: e12748
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Publication
38020910 | J:347857
 
First Author: Xie B
Year: 2023
Journal: Front Cell Dev Biol
Title: p75NTR promotes tooth rhythmic mineralization via upregulation of BMAL1/CLOCK.
Volume: 11
Pages: 1283878
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Publication
25083013 | J:279954
First Author: Pellegrino R
Year: 2014
Journal: Sleep
Title: A novel BHLHE41 variant is associated with short sleep and resistance to sleep deprivation in humans.
Volume: 37
Issue: 8
Pages: 1327-36
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Publication
7723623 | J:22680
First Author: O'Hara BF
Year: 1995
Journal: Brain Res Mol Brain Res
Title: GABAA, GABAC, and NMDA receptor subunit expression in the suprachiasmatic nucleus and other brain regions.
Volume: 28
Issue: 2
Pages: 239-50
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Publication
9435649 | J:45459
First Author: Valentinuzzi VS
Year: 1997
Journal: Am J Physiol
Title: Effects of aging on the circadian rhythm of wheel-running activity in C57BL/6 mice.
Volume: 273
Issue: 6 Pt 2
Pages: R1957-64
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Publication
9706410 | J:52618
First Author: Li XM
Year: 1998
Journal: Chronobiol Int
Title: Pharmacological modulation of cisplatin toxicity rhythms with buthionine sulfoximine in mice bearing pancreatic adenocarcinoma (PO3).
Volume: 15
Issue: 4
Pages: 323-35
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Publication
21364973 | J:170680
First Author: Rey G
Year: 2011
Journal: PLoS Biol
Title: Genome-wide and phase-specific DNA-binding rhythms of BMAL1 control circadian output functions in mouse liver.
Volume: 9
Issue: 2
Pages: e1000595
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Publication
24009680 | J:205942
First Author: Ruby NF
Year: 2013
Journal: PLoS One
Title: Spatial memory and long-term object recognition are impaired by circadian arrhythmia and restored by the GABAAAntagonist pentylenetetrazole.
Volume: 8
Issue: 8
Pages: e72433
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Publication
30481281 | J:267370
First Author: Tsuchiya S
Year: 2018
Journal: Invest Ophthalmol Vis Sci
Title: Adrenal and Glucocorticoid Effects on the Circadian Rhythm of Murine Intraocular Pressure.
Volume: 59
Issue: 13
Pages: 5641-5647
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Publication
21203370 | J:290585
First Author: Jiang P
Year: 2011
Journal: Sleep
Title: Behavioral and genetic dissection of a mouse model for advanced sleep phase syndrome.
Volume: 34
Issue: 1
Pages: 39-48
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Publication
17974007 | J:308407
 
First Author: Hofstetter JR
Year: 2007
Journal: J Circadian Rhythms
Title: A QTL on mouse chromosome 12 for the genetic variance in free-running circadian period between inbred strains of mice.
Volume: 5
Pages: 7
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Publication
37230230 | J:338542
     
First Author: Chen M
Year: 2023
Journal: J Hepatol
Title: Reprogramming of rhythmic liver metabolism by intestinal clock.
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Publication
38218537 | J:345942
 
First Author: Wang L
Year: 2024
Journal: Mol Metab
Title: Long non-coding RNA LncCplx2 regulates glucose homeostasis and pancreatic β cell function.
Volume: 80
Pages: 101878
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Publication
37156620 | J:355812
First Author: Bafna A
Year: 2023
Journal: Genome Res
Title: Dynamic modulation of genomic enhancer elements in the suprachiasmatic nucleus, the site of the mammalian circadian clock.
Volume: 33
Issue: 5
Pages: 673-688
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Protein
Q9QYH6
Organism: Mus musculus/domesticus
Length: 775  
Fragment?: false
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Protein
Q3U1J4
Organism: Mus musculus/domesticus
Length: 1140  
Fragment?: false
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Protein
Q9D906
Organism: Mus musculus/domesticus
Length: 698  
Fragment?: false
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Protein
O89119
Organism: Mus musculus/domesticus
Length: 1115  
Fragment?: false
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Protein
Q8CBC2
Organism: Mus musculus/domesticus
Length: 527  
Fragment?: false
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Protein
A0A0A0MQN4
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
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Protein
Q571N9
Organism: Mus musculus/domesticus
Length: 798  
Fragment?: true
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Protein
Q3UIL5
Organism: Mus musculus/domesticus
Length: 775  
Fragment?: false
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Protein
Q91W72
Organism: Mus musculus/domesticus
Length: 550  
Fragment?: false
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Protein
Q3UXM3
Organism: Mus musculus/domesticus
Length: 775  
Fragment?: false
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Protein
Q3ULS8
Organism: Mus musculus/domesticus
Length: 599  
Fragment?: true
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Protein
S4R2T5
Organism: Mus musculus/domesticus
Length: 671  
Fragment?: false
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Protein
E9PV88
Organism: Mus musculus/domesticus
Length: 426  
Fragment?: false
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Protein
Q8K2H5
Organism: Mus musculus/domesticus
Length: 775  
Fragment?: false
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Protein
Q3TM87
Organism: Mus musculus/domesticus
Length: 698  
Fragment?: false
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Protein
B9EIT7
Organism: Mus musculus/domesticus
Length: 1116  
Fragment?: false
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Protein
Q3TAB9
Organism: Mus musculus/domesticus
Length: 698  
Fragment?: false
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Protein
Q91YC8
Organism: Mus musculus/domesticus
Length: 994  
Fragment?: false
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Publication
25163632 | -
First Author: Delhanty PJ
Year: 2014
Journal: Mol Biol Rep
Title: Functional characterization of a new human melanocortin-4 receptor homozygous mutation (N72K) that is associated with early-onset obesity.
Volume: 41
Issue: 12
Pages: 7967-72
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Publication
32248247 | -
First Author: Xu Y
Year: 2020
Journal: Cell Mol Life Sci
Title: Melanocortin 5 receptor signaling pathway in health and disease.
Volume: 77
Issue: 19
Pages: 3831-3840
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Publication
12646665 | -
First Author: Farooqi IS
Year: 2003
Journal: N Engl J Med
Title: Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene.
Volume: 348
Issue: 12
Pages: 1085-95
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Publication
23869017 | -
First Author: Sebag JA
Year: 2013
Journal: Science
Title: Developmental control of the melanocortin-4 receptor by MRAP2 proteins in zebrafish.
Volume: 341
Issue: 6143
Pages: 278-81
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Publication
22170053 | -
First Author: Hitomi K
Year: 2012
Journal: J Biol Chem
Title: Eukaryotic class II cyclobutane pyrimidine dimer photolyase structure reveals basis for improved ultraviolet tolerance in plants.
Volume: 287
Issue: 15
Pages: 12060-9
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Publication
21892138 | -
First Author: Kiontke S
Year: 2011
Journal: EMBO J
Title: Crystal structures of an archaeal class II DNA photolyase and its complex with UV-damaged duplex DNA.
Volume: 30
Issue: 21
Pages: 4437-49
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Publication
17204848 | -
First Author: Meijer WH
Year: 2007
Journal: Autophagy
Title: ATG genes involved in non-selective autophagy are conserved from yeast to man, but the selective Cvt and pexophagy pathways also require organism-specific genes.
Volume: 3
Issue: 2
Pages: 106-16
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Protein Domain
IPR001908 | MC3-5R
Type: Family
Description: G protein-coupled receptors (GPCRs) constitute a vast protein family that encompasses a wide range of functions, including various autocrine, paracrine and endocrine processes. They show considerable diversity at the sequence level, on the basis of which they can be separated into distinct groups []. The term clan can be used to describe the GPCRs, as they embrace a group of families for which there are indications of evolutionary relationship, but between which there is no statistically significant similarity in sequence []. The currently known clan members include rhodopsin-like GPCRs (Class A, GPCRA), secretin-like GPCRs (Class B, GPCRB), metabotropic glutamate receptor family (Class C, GPCRC), fungal mating pheromone receptors (Class D, GPCRD), cAMP receptors (Class E, GPCRE) and frizzled/smoothened (Class F, GPCRF) [, , , , ]. GPCRs are major drug targets, and are consequently the subject of considerable research interest. It has been reported that the repertoire of GPCRs for endogenous ligands consists of approximately 400 receptors in humans and mice []. Most GPCRs are identified on the basis of their DNA sequences, rather than the ligand they bind, those that are unmatched to known natural ligands are designated by as orphan GPCRs, or unclassified GPCRs [].The rhodopsin-like GPCRs (GPCRA) represent a widespread protein family that includes hormone, neurotransmitter and light receptors, all of which transduce extracellular signals through interaction with guanine nucleotide-binding (G) proteins. Although their activating ligands vary widely in structure and character, the amino acid sequences of the receptors are very similar and are believed to adopt a common structural framework comprising 7 transmembrane (TM) helices [, , ].Adrenocorticotrophin (ACTH), melanocyte-stimulating hormones (MSH) andbeta-endorphin are peptide products of pituitary pro-opiomelanocortin.ACTH regulates synthesis and release of glucocorticoids and aldosteronein the adrenal cortex; it also has a trophic action on these cells.ACTH and beta-endorphin are synthesised and released in response tocorticotrophin-releasing factor at times of stress (heat, cold, infections,etc.) - their release leads to increased metabolism and analgesia.MSH has a trophic action on melanocytes, and regulates pigment productionin fish and amphibia. The ACTH receptor is found in high levels inthe adrenal cortex - binding sites are present in lower levels in theCNS. The MSH receptor is expressed in high levels in melanocytes,melanomas and their derived cell lines. Receptors are found in lowlevels in the CNS. MSH regulates temperature control in the septal regionof the brain and releases prolactin from the pituitary.This entry represents Melanocortin receptor 3-5 (MC3-5R) from chordates. These protein are receptors for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. MC3R is required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain []. MC4R plays a central role in energy homeostasis and somatic growth [, , ]. MC5R is a possible mediator of the immunomodulation properties of melanocortins, playing a role in immune reaction and inflammatory response as well as in the regulation of sexual behaviour, thermoregulation, and exocrine secretion [].
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Publication
21930935 | J:177139
First Author: Lee HM
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1.
Volume: 108
Issue: 39
Pages: 16451-6
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Publication
14640981 | J:88011
First Author: Llorian M
Year: 2004
Journal: Biochem J
Title: SIPP1, a novel pre-mRNA splicing factor and interactor of protein phosphatase-1.
Volume: 378
Issue: Pt 1
Pages: 229-38
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Publication
18689497 | J:141318
First Author: Brüchert N
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Inhibitor-2 prevents protein phosphatase 1-induced cardiac hypertrophy and mortality.
Volume: 295
Issue: 4
Pages: H1539-46
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Publication
15226296 | J:92568
First Author: Hrabchak C
Year: 2004
Journal: J Biol Chem
Title: Identification of the spermatogenic zip protein Spz1 as a putative protein phosphatase-1 (PP1) regulatory protein that specifically binds the PP1cgamma2 splice variant in mouse testis.
Volume: 279
Issue: 35
Pages: 37079-86
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Publication
21471512 | J:171812
First Author: Luo X
Year: 2011
Journal: Diabetes
Title: Fasting-induced protein phosphatase 1 regulatory subunit contributes to postprandial blood glucose homeostasis via regulation of hepatic glycogenesis.
Volume: 60
Issue: 5
Pages: 1435-45
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Publication
15010208 | J:88468
First Author: Thompson CL
Year: 2004
Journal: Brain Res Mol Brain Res
Title: Further evidence for the role of cryptochromes in retinohypothalamic photoreception/phototransduction.
Volume: 122
Issue: 2
Pages: 158-66
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Publication
12522242 | J:81500
First Author: Van Gelder RN
Year: 2003
Journal: Science
Title: Reduced pupillary light responses in mice lacking cryptochromes.
Volume: 299
Issue: 5604
Pages: 222
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Publication
27840026 | J:249123
First Author: Huber AL
Year: 2016
Journal: Mol Cell
Title: CRY2 and FBXL3 Cooperatively Degrade c-MYC.
Volume: 64
Issue: 4
Pages: 774-789
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Publication
27821480 | J:244628
 
First Author: Su CH
Year: 2017
Journal: Mol Cell Biol
Title: RBM4 Regulates Neuronal Differentiation of Mesenchymal Stem Cells by Modulating Alternative Splicing of Pyruvate Kinase M.
Volume: 37
Issue: 3
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Publication
31672960 | J:294532
First Author: Kim MK
Year: 2019
Journal: Cell Death Dis
Title: Salt-inducible kinase 1 regulates bone anabolism via the CRTC1-CREB-Id1 axis.
Volume: 10
Issue: 11
Pages: 826
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Publication
17369396 | J:119479
First Author: Parra M
Year: 2007
Journal: Genes Dev
Title: Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes.
Volume: 21
Issue: 6
Pages: 638-43
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Publication
21525287 | J:171421
First Author: VanDunk C
Year: 2011
Journal: J Neurosci
Title: Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus.
Volume: 31
Issue: 17
Pages: 6457-67
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Publication
9801304 | J:51295
First Author: Kobayashi K
Year: 1998
Journal: Nucleic Acids Res
Title: Characterization of photolyase/blue-light receptor homologs in mouse and human cells.
Volume: 26
Issue: 22
Pages: 5086-92
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Publication
23575670 | J:209472
 
First Author: Ono D
Year: 2013
Journal: Nat Commun
Title: Cryptochromes are critical for the development of coherent circadian rhythms in the mouse suprachiasmatic nucleus.
Volume: 4
Pages: 1666
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Publication
18222992 | J:181670
First Author: Davies VJ
Year: 2008
Journal: Brain
Title: A missense mutation in the murine Opa3 gene models human Costeff syndrome.
Volume: 131
Issue: Pt 2
Pages: 368-80
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Publication
16260624 | J:189992
First Author: Lin JC
Year: 2005
Journal: Mol Cell Biol
Title: Exon selection in alpha-tropomyosin mRNA is regulated by the antagonistic action of RBM4 and PTB.
Volume: 25
Issue: 22
Pages: 10111-21
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Publication
19801630 | J:157800
First Author: Lin JC
Year: 2009
Journal: J Biol Chem
Title: RNA-binding motif protein 4 translocates to cytoplasmic granules and suppresses translation via argonaute2 during muscle cell differentiation.
Volume: 284
Issue: 50
Pages: 34658-65
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Publication
1847109 | J:10983
First Author: Baehr W
Year: 1991
Journal: FEBS Lett
Title: Complete cDNA sequences of mouse rod photoreceptor cGMP phosphodiesterase alpha- and beta-subunits, and identification of beta'-, a putative beta-subunit isozyme produced by alternative splicing of the beta-subunit gene.
Volume: 278
Issue: 1
Pages: 107-14
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Publication
23479632 | J:194246
First Author: Barabas P
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Role of ELOVL4 and very long-chain polyunsaturated fatty acids in mouse models of Stargardt type 3 retinal degeneration.
Volume: 110
Issue: 13
Pages: 5181-6
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Publication
11483358 | J:71485
First Author: Simpson A
Year: 2001
Journal: Gene
Title: Differential expression and subcellular distribution of the mouse metastasis-associated proteins Mta1 and Mta3.
Volume: 273
Issue: 1
Pages: 29-39
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Publication
17381077 | J:128272
First Author: Hrabchak C
Year: 2007
Journal: Biochemistry
Title: A testis specific isoform of endophilin B1, endophilin B1t, interacts specifically with protein phosphatase-1c gamma2 in mouse testis and is abnormally expressed in PP1c gamma null mice.
Volume: 46
Issue: 15
Pages: 4635-44
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Publication
20140255 | J:158005
First Author: Romito A
Year: 2010
Journal: PLoS One
Title: Lack of sik1 in mouse embryonic stem cells impairs cardiomyogenesis by down-regulating the cyclin-dependent kinase inhibitor p57kip2.
Volume: 5
Issue: 2
Pages: e9029
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Publication
25605614 | J:244826
First Author: Matsuura M
Year: 2015
Journal: Mol Reprod Dev
Title: TMEM225: a possible protein phosphatase 1γ2 (PP1γ2) regulator localizes to the equatorial segment in mouse spermatozoa.
Volume: 82
Issue: 2
Pages: 139-48
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Publication
16354703 | J:104214
First Author: Greenberg CC
Year: 2006
Journal: Mol Cell Biol
Title: Central role for protein targeting to glycogen in the maintenance of cellular glycogen stores in 3T3-L1 adipocytes.
Volume: 26
Issue: 1
Pages: 334-42
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Publication
12752778 | J:128149
First Author: Semo M
Year: 2003
Journal: Eur J Neurosci
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