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Search results 7801 to 7900 out of 8780 for Shh

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Type Details Score
GXD Expression
GXD Expression
Probe: MGI:6885873
Assay Type: RNA in situ
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3676122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6885885
Age: embryonic day 14.5
Image: 3E/G
Note: Expression in a fraction of Shh expressing cells within cell clusters.
Specimen Label: 3E/G
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5002350
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-25
Strength: Strong
Sex: Female
Emaps: EMAPS:3803227
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6717476
Age: postnatal newborn
Image: S2B
Note: Marked expression in Shh mutant mice. Mullerian duct barely recognizable as a tubular structure.
Specimen Label: S2B
Detected: true
Specimen Num: 2
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Gene
64327 | LMBR1
Type: gene
Organism: human
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HT Experiment
GSE129730 | Single cell RNA-seq shows cellular heterogeneity and lineage expansion in a mouse model of SHH-driven medulloblastoma support resistance to SHH inhibitor therapy
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
24522195 | -
First Author: Jakobs P
Year: 2014
Journal: J Cell Sci
Title: Scube2 enhances proteolytic Shh processing from the surface of Shh-producing cells.
Volume: 127
Issue: Pt 8
Pages: 1726-37
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HT Experiment
GSE80958 | Sonic hedgehog signaling promotes basal radial glia and 1 intermediate progenitor cell
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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GXD Expression
GXD Expression
 
Probe: MGI:6283460
Assay Type: RNA in situ
Annotation Date: 2019-03-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6283513
Age: embryonic day 10.5
Note: Expressed in the ventrolateral side of the rostral mesencephalon. Within the regions in which Shh was expressed.
Specimen Label: 9A
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:6404230
Assay Type: RNA in situ
Annotation Date: 2020-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3264621
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6404390
Age: embryonic day 13.5
Image: 3C
Note: Expression in single cartilage primordium, its volume 2-3x larger than that of the single element of Shh single mutant.
Specimen Label: 3C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6404230
Assay Type: RNA in situ
Annotation Date: 2020-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3264621
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6404390
Age: embryonic day 13.5
Image: 3D
Note: Expression in single cartilage primordium, its volume 2-3x larger than that of the single element of Shh single mutant.
Specimen Label: 3D
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:2676494
Assay Type: RNA in situ
Annotation Date: 2003-10-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1614013
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:2676619
Age: embryonic day 8.5
Image: 7A
Note: Strong expression in ventral and intermediate parts of P1/2 (diencephalon) and anterior midbrain just dorsal to Shh expression domain.
Specimen Label: 7A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6283460
Assay Type: RNA in situ
Annotation Date: 2019-03-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6283513
Age: embryonic day 10.5
Note: Expressed in the zona limitans intrathalamica, caudal diencephalon and the ventral thalamus. Within the regions in which Shh was expressed.
Specimen Label: 9A
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:2676494
Assay Type: RNA in situ
Annotation Date: 2003-10-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1614413
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:2676619
Age: embryonic day 8.5
Image: 7A
Note: Strong expression in ventral and intermediate parts of P1/2 (diencephalon) and anterior midbrain just dorsal to Shh expression domain.
Specimen Label: 7A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6866979
Assay Type: RNA in situ
Annotation Date: 2022-02-10
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1614413
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:6866994
Age: embryonic day 8.5
Image: 3B Hes5 Gas1-/-
Note: As early as E8.5, preceding defect in Shh pathway reduced expression in rostral neuroepithelium compared with controls. .
Specimen Label: 3B Hes5 Gas1-/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7664629
Assay Type: RNA in situ
Annotation Date: 2024-07-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1736323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7664634
Age: embryonic day 15.5
Image: 2Y
Note: Strong expression in thickened palatal oral epithelium in region overlapping with but extending beyond that of Shh expression.
Specimen Label: 2Y
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:1334951
Assay Type: RNA in situ
Annotation Date: 2001-04-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1724719
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:1933301
Age: embryonic day 11.5
Image: 6E
Note: The domain of Shh expressing cells expands ventrally to the level of ectopic Fgf8 staining in the ventral ectoderm.
Specimen Label: 6E
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:1277646
Assay Type: RNA in situ
Annotation Date: 1998-12-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677918
Pattern: Graded
Stage: TS18
Assay Id: MGI:1314737
Age: embryonic day 11.0
Image: 6g
Note: Xt;ld double homozygous hindlimb bud with posterior Gli expression. Gli expression is highest in cells close to the Shh domain.
Specimen Label: 6g
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:1277646
Assay Type: RNA in situ
Annotation Date: 1998-12-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677918
Pattern: Graded
Stage: TS18
Assay Id: MGI:1314737
Age: embryonic day 11.0
Image: 6h
Note: Xt;ld double homozygous hindlimb bud with apical Gli expression. Gli expression is highest in cells close to the Shh domain.
Specimen Label: 6h
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610111
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:7643429
Age: embryonic day 7.5
Note: Expression at periphery of notochordal plate in a domain adjacent to and partially overlapping with Shh expression.
Specimen Label: 2C
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:7287685
Assay Type: RNA in situ
Annotation Date: 2022-06-23
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1736422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7287694
Age: embryonic day 14.5
Note: Expressed in condensed mesenchyme adjacent to regions of Shh expression. Not expressed in the medial epithelial seam during fusion.
Specimen Label: 2F
Detected: true
Specimen Num: 3
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DO Term
DOID:0111564 | hypoplastic or aplastic tibia with polydactyly
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DO Term
DOID:0111380 | solitary median maxillary central incisor
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DO Term
DOID:0111818 | syndactyly type 4
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Allele
Shh<tm3(cre)Chg> | MGI:3759540
Name: sonic hedgehog; targeted mutation 3, Chin Chiang
Allele Type: Targeted
Attribute String: Recombinase
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Allele
Hm<em2Tshir> | MGI:6143854
Name: hammer toe; endonuclease-mediated mutation 2, Toshihiko Shiroishi
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Strain
MGI:6474568 | C57BL/6JJcl-Del(5Rr78-Rr116)2Tshir/Ms
Attribute String: mutant strain, coisogenic, endonuclease-mediated mutation
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Allele
Del(5Rr78-Rr77)3Tshir | MGI:6470876
Name: deletion, Chr 5, Toshihiko Shiroishi 3
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Strain
MGI:6474569 | C57BL/6JJcl-Del(5Rr78-Rr77)3Tshir/Ms
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6429541 | C57BL/6JSmoc-Shh<em1(cre/ERT2)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6476266 | C57BL/6JSmoc-Shh<em2(icre)Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Tg(KRT14-Shh)#Cobm | MGI:7332932
Name: transgene insertion, Martyn T Cobourne
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:6353142 | B6-Del(5Rr459-Rr114)4Tshir/MsRbrc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Rr29<em1Andg> | MGI:7703756
Name: regulatory region 29; endonuclease-mediated mutation 1, Guillaume Andrey
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Genotype
Genotype
Symbol: Tg(KRT14-Shh)#Cobm/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(5Rr78-Rr77)3Tshir/Del(5Rr78-Rr77)3Tshir
Background: involves: C57BL/6JJcl
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(5Rr78-Rr116)2Tshir/Del(5Rr78-Rr116)2Tshir
Background: involves: C57BL/6JJcl
Zygosity: hm
Has Mutant Allele: true
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GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331157
Age: embryonic day 11.5
Image: 6B
Note: Ihh expression was detected in the distal limb bud and tail bud. However, at the posterior margin where Shh was normally expressed, no Ihh expression was detected.
Specimen Label: 6B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1320893
Assay Type: RNA in situ
Annotation Date: 1999-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1792122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:1320902
Age: embryonic day 14.5
Image: 1V
Note: In the molars Gli1 was expressed in a region of the tooth germ that appeared to surround the area of the enamel that was marked by Shh expression.
Specimen Label: 1V
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331157
Age: embryonic day 11.5
Image: 6B
Note: Ihh expression was detected in the distal limb bud and tail bud. However, at the posterior margin where Shh was normally expressed, no Ihh expression was detected.
Specimen Label: 6B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:2676494
Assay Type: RNA in situ
Annotation Date: 2003-10-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1614013
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:2676619
Age: embryonic day 8.5
Image: 7B
Note: Strong expression in ventral and intermediate parts of P1/2 and anterior midbrain just dorsal to Shh expression domain. No expression in dorsal regions of diencephalon and midbrain.
Specimen Label: 7B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7664630
Assay Type: RNA in situ
Annotation Date: 2024-07-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3648123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7664635
Age: embryonic day 15.5
Image: 2EE
Note: Expression in distal epithelium of hair peg, overlapping with that of Shh but extending beyond Shh-expressing region, up outer walls of hair peg.
Specimen Label: 2EE
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:21330
Assay Type: RNA in situ
Annotation Date: 1999-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1345515
Age: embryonic day 11.5
Image: 6H
Note: Pax2 expression has extended medially into the gap left by Shh, so that the expression pattern is now continuous ventrally, yet still not overlapping the Shh expression domain.
Specimen Label: 6H
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6283459
Assay Type: RNA in situ
Annotation Date: 2019-03-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6283549
Age: embryonic day 10.5
Note: Expressed ventrolaterally in the diencephalon with the dorsal extension to zona limitans intrathalamica. Within the regions in which Shh was expressed.
Specimen Label: 9B
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:2676494
Assay Type: RNA in situ
Annotation Date: 2003-10-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1614413
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:2676619
Age: embryonic day 8.5
Image: 7B
Note: Strong expression in ventral and intermediate parts of P1/2 and anterior midbrain just dorsal to Shh expression domain. No expression in dorsal regions of diencephalon and midbrain.
Specimen Label: 7B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:21330
Assay Type: RNA in situ
Annotation Date: 1999-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1690219
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1345515
Age: embryonic day 11.5
Image: 6H
Note: Pax2 expression has extended medially into the gap left by Shh, so that the expression pattern is now continuous ventrally, yet still not overlapping the Shh expression domain.
Specimen Label: 6H
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:1320893
Assay Type: RNA in situ
Annotation Date: 1999-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1794222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:1320902
Age: embryonic day 14.5
Image: 1V
Note: In the molars Gli1 was expressed in a region of the tooth germ that appeared to surround the area of the enamel that was marked by Shh expression.
Specimen Label: 1V
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677919
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331157
Age: embryonic day 11.5
Image: 6B
Note: Ihh expression was detected in the distal limb bud and tail bud. However, at the posterior margin where Shh was normally expressed, no Ihh expression was detected.
Specimen Label: 6B
Detected: true
Specimen Num: 2
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Allele
Foxa2<tm1Jrt> | MGI:1857725
Name: forkhead box A2; targeted mutation 1, Janet Rossant
Allele Type: Targeted
Attribute String: Null/knockout
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HT Experiment
GSE203228 | Follistatin regulates sonic hedgehog-dependent tonotopic organization of the apical cochlea responsible for low-frequency hearing
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Strain
MGI:6331733 | 129-Shh<tm1Chg>/AnuApb
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:4887442 | 129-Shh<tm1Chg>/H
Attribute String: targeted mutation
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Allele
Raz | MGI:2683726
 
Name: replicated anterior zeugopod, inversion
Allele Type: Radiation induced
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Allele
Tg(tetO-Shh)1Jaw | MGI:3051146
Name: transgene insertion 1, Jeffrey A Whitsett
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
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Allele
Hm<Hm+em1Tshir> | MGI:6140171
Name: hammer toe; endonuclease-mediated revertant 1, Toshihiko Shiroishi
Allele Type: Endonuclease-mediated
Attribute String: No functional change
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Allele
Rr115<em1Bobh> | MGI:7367576
Name: regulatory region 115; endonuclease-mediated mutation 1, Robert E Hill
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Igs2<em2(Rr518-lacZ)Axvi> | MGI:7713139
Name: intergenic site 2; endonuclease-mediated mutation 2, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em5(Rr521-lacZ)Axvi> | MGI:7713142
Name: intergenic site 2; endonuclease-mediated mutation 5, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em12(Rr528-lacZ)Axvi> | MGI:7713149
Name: intergenic site 2; endonuclease-mediated mutation 12, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em16(Rr532-lacZ)Axvi> | MGI:7713153
Name: intergenic site 2; endonuclease-mediated mutation 16, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em18(Rr534-lacZ)Axvi> | MGI:7713155
Name: intergenic site 2; endonuclease-mediated mutation 18, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em20(Rr535-lacZ)Axvi> | MGI:7713156
Name: intergenic site 2; endonuclease-mediated mutation 20, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em21(Rr536-lacZ)Axvi> | MGI:7713158
Name: intergenic site 2; endonuclease-mediated mutation 21, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em24(Rr539-lacZ)Axvi> | MGI:7713162
Name: intergenic site 2; endonuclease-mediated mutation 24, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em29(Rr171333-lacZ)Axvi> | MGI:7713164
Name: intergenic site 2; endonuclease-mediated mutation 29, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em30(Rr306581-lacZ)Axvi> | MGI:7713166
Name: intergenic site 2; endonuclease-mediated mutation 30, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em25(Rr540-lacZ)Axvi> | MGI:7713177
Name: intergenic site 2; endonuclease-mediated mutation 25, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em23(Rr538-lacZ)Axvi> | MGI:7713161
Name: intergenic site 2; endonuclease-mediated mutation 23, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em27(Rr129102-lacZ)Axvi> | MGI:7713176
Name: intergenic site 2; endonuclease-mediated mutation 27, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em1(Rr517-lacZ)Axvi> | MGI:7713138
Name: intergenic site 2; endonuclease-mediated mutation 1, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em3(Rr519-lacZ)Axvi> | MGI:7713140
Name: intergenic site 2; endonuclease-mediated mutation 3, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em4(Rr520-lacZ)Axvi> | MGI:7713141
Name: intergenic site 2; endonuclease-mediated mutation 4, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em6(Rr522-lacZ)Axvi> | MGI:7713143
Name: intergenic site 2; endonuclease-mediated mutation 6, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em7(Rr523-lacZ)Axvi> | MGI:7713144
Name: intergenic site 2; endonuclease-mediated mutation 7, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em8(Rr524-lacZ)Axvi> | MGI:7713145
Name: intergenic site 2; endonuclease-mediated mutation 8, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em9(Rr525-lacZ)Axvi> | MGI:7713146
Name: intergenic site 2; endonuclease-mediated mutation 9, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em10(Rr526-lacZ)Axvi> | MGI:7713147
Name: intergenic site 2; endonuclease-mediated mutation 10, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em11(Rr527-lacZ)Axvi> | MGI:7713148
Name: intergenic site 2; endonuclease-mediated mutation 11, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em13(Rr529-lacZ)Axvi> | MGI:7713150
Name: intergenic site 2; endonuclease-mediated mutation 13, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em14(Rr530-lacZ)Axvi> | MGI:7713151
Name: intergenic site 2; endonuclease-mediated mutation 14, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em15(Rr531-lacZ)Axvi> | MGI:7713152
Name: intergenic site 2; endonuclease-mediated mutation 15, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em17(Rr533-lacZ)Axvi> | MGI:7713154
Name: intergenic site 2; endonuclease-mediated mutation 17, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Igs2<em22(Rr537-lacZ)Axvi> | MGI:7713160
Name: intergenic site 2; endonuclease-mediated mutation 22, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Genotype
Genotype
Symbol: Shh/Shh
Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Shh/Shh
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Shh/Shh
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Shh/Shh
Background: involves: 129S1/Sv * 129X1/SvJ * Swiss Webster
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Shh/Shh
Background: involves: 101/H * 129S1/Sv * 129X1/SvJ * C3H/HeH * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Shh/Shh<+>
Background: involves: 129S1/Sv * 129X1/SvJ * Swiss Webster
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Shh/Shh<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Shh/Shh
Background: either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * Swiss Webster)
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Shh/Shh
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Shh/Shh
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Shh/Shh
Background: involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Shh/Shh<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Shh/Shh
Background: involves: 129S1/Sv * 129X1/SvJ * C3H
Zygosity: hm
Has Mutant Allele: true
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HT Experiment
GSE102844 | Analysis of the Effect of Fibulin-1 on Fibroblast Growth Factor 8 Signaling
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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Publication
11449277 | J:70423
First Author: Eggenschwiler JT
Year: 2001
Journal: Nature
Title: Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway.
Volume: 412
Issue: 6843
Pages: 194-8
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DO Term
DOID:0111350 | Laurin-Sandrow syndrome
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HT Experiment
GSE100934 | Whole transcriptome sequencing of mouse notochord-derived cells at developmental stages E12.5 and P0
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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GXD Expression
GXD Expression
Probe: MGI:12279
Assay Type: RNA in situ
Annotation Date: 2019-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6355445
Age: embryonic day 12.5
Image: S1 E12.5
Note: Compared to adjacent sections, the ventral limit of Gli2 expression abuts the dorsal limit of Foxa2 expression at the alar/basal boundary, and there is a gap between Shh and Gli2 expression in the ventral midbrain.
Specimen Label: S1 E12.5
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:7664630
Assay Type: RNA in situ
Annotation Date: 2024-07-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3275823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7664635
Age: embryonic day 15.5
Image: 2GG
Note: Following fusion, expression in basal layer of eyelid epitehlium originating from both upper and lower lid primordia. Expression restricted to basal layer eyelid epithelium, but with broader expression teritory that overlaps and extends beyond region of Shh expression.
Specimen Label: 2GG
Detected: true
Specimen Num: 6
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