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Search results 801 to 900 out of 1002 for Apobec1

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Type Details Score
Publication
First Author: Levin MD
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: K(ATP) channel gain-of-function leads to increased myocardial L-type Ca(2+) current and contractility in Cantu syndrome.
Volume: 113
Issue: 24
Pages: 6773-8
Publication
First Author: Zhang X
Year: 2020
Journal: J Am Heart Assoc
Title: NULP1 Alleviates Cardiac Hypertrophy by Suppressing NFAT3 Transcriptional Activity.
Volume: 9
Issue: 16
Pages: e016419
Publication
First Author: McDermott-Roe C
Year: 2017
Journal: PLoS One
Title: Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function.
Volume: 12
Issue: 2
Pages: e0170458
Publication
First Author: Yue Z
Year: 2019
Journal: Cell Rep
Title: PDGFR-β Signaling Regulates Cardiomyocyte Proliferation and Myocardial Regeneration.
Volume: 28
Issue: 4
Pages: 966-978.e4
Publication
First Author: Tomar D
Year: 2016
Journal: Cell Rep
Title: MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics.
Volume: 15
Issue: 8
Pages: 1673-85
Publication
First Author: Luongo TS
Year: 2017
Journal: Nature
Title: The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability.
Volume: 545
Issue: 7652
Pages: 93-97
Publication
First Author: Yang T
Year: 2014
Journal: Circ Heart Fail
Title: Novel protective role of endogenous cardiac myocyte P2X4 receptors in heart failure.
Volume: 7
Issue: 3
Pages: 510-8
Publication  
First Author: Jean-Charles PY
Year: 2017
Journal: JCI Insight
Title: Mdm2 regulates cardiac contractility by inhibiting GRK2-mediated desensitization of β-adrenergic receptor signaling.
Volume: 2
Issue: 17
Publication
First Author: Schreiber R
Year: 2017
Journal: Cell Metab
Title: Cold-Induced Thermogenesis Depends on ATGL-Mediated Lipolysis in Cardiac Muscle, but Not Brown Adipose Tissue.
Volume: 26
Issue: 5
Pages: 753-763.e7
Publication
First Author: Trent CM
Year: 2014
Journal: J Lipid Res
Title: Lipoprotein lipase activity is required for cardiac lipid droplet production.
Volume: 55
Issue: 4
Pages: 645-58
Publication
First Author: Li RG
Year: 2024
Journal: Nat Cardiovasc Res
Title: YAP induces a neonatal-like pro-renewal niche in the adult heart.
Volume: 3
Issue: 3
Pages: 283-300
Publication
First Author: Eckle T
Year: 2012
Journal: Nat Med
Title: Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia.
Volume: 18
Issue: 5
Pages: 774-82
Publication
First Author: Zlatanova I
Year: 2019
Journal: Circulation
Title: Iron Regulator Hepcidin Impairs Macrophage-Dependent Cardiac Repair After Injury.
Volume: 139
Issue: 12
Pages: 1530-1547
Publication
First Author: Cardoso AC
Year: 2020
Journal: Nat Metab
Title: Mitochondrial Substrate Utilization Regulates Cardiomyocyte Cell Cycle Progression.
Volume: 2
Issue: 2
Pages: 167-178
Publication
First Author: Kritzer MD
Year: 2014
Journal: Circ Heart Fail
Title: The scaffold protein muscle A-kinase anchoring protein β orchestrates cardiac myocyte hypertrophic signaling required for the development of heart failure.
Volume: 7
Issue: 4
Pages: 663-72
Publication
First Author: Jin L
Year: 2022
Journal: Circulation
Title: FGF21-Sirtuin 3 Axis Confers the Protective Effects of Exercise Against Diabetic Cardiomyopathy by Governing Mitochondrial Integrity.
Volume: 146
Issue: 20
Pages: 1537-1557
Publication
First Author: Hirose K
Year: 2019
Journal: Science
Title: Evidence for hormonal control of heart regenerative capacity during endothermy acquisition.
Volume: 364
Issue: 6436
Pages: 184-188
Publication
First Author: Zhang D
Year: 2010
Journal: J Clin Invest
Title: MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice.
Volume: 120
Issue: 8
Pages: 2805-16
Publication  
First Author: Wu SP
Year: 2015
Journal: Nat Commun
Title: Increased COUP-TFII expression in adult hearts induces mitochondrial dysfunction resulting in heart failure.
Volume: 6
Pages: 8245
Publication  
First Author: Wintzinger M
Year: 2022
Journal: Mol Metab
Title: Impact of circadian time of dosing on cardiomyocyte-autonomous effects of glucocorticoids.
Volume: 62
Pages: 101528
Publication
First Author: Ushijima T
Year: 2018
Journal: J Biol Chem
Title: The actin-organizing formin protein Fhod3 is required for postnatal development and functional maintenance of the adult heart in mice.
Volume: 293
Issue: 1
Pages: 148-162
Publication
First Author: Nakai A
Year: 2007
Journal: Nat Med
Title: The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress.
Volume: 13
Issue: 5
Pages: 619-24
Publication  
First Author: Ali SR
Year: 2024
Journal: J Cardiovasc Aging
Title: Hypoxia-induced stabilization of HIF2A promotes cardiomyocyte proliferation by attenuating DNA damage.
Volume: 4
Issue: 1
Publication
First Author: Lu Z
Year: 2009
Journal: Circulation
Title: Loss of cardiac phosphoinositide 3-kinase p110 alpha results in contractile dysfunction.
Volume: 120
Issue: 4
Pages: 318-25
Publication
First Author: Lam NT
Year: 2022
Journal: Nat Cardiovasc Res
Title: Targeting calcineurin induces cardiomyocyte proliferation in adult mice.
Volume: 1
Issue: 7
Pages: 679-688
Publication
First Author: Santamans AM
Year: 2021
Journal: PLoS Biol
Title: p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1.
Volume: 19
Issue: 11
Pages: e3001447
Publication
First Author: Song M
Year: 2015
Journal: Cell Metab
Title: Mitochondrial fission and fusion factors reciprocally orchestrate mitophagic culling in mouse hearts and cultured fibroblasts.
Volume: 21
Issue: 2
Pages: 273-85
Publication
First Author: Nguyen NUN
Year: 2020
Journal: Nature
Title: A calcineurin-Hoxb13 axis regulates growth mode of mammalian cardiomyocytes.
Volume: 582
Issue: 7811
Pages: 271-276
Publication
First Author: Campbell JE
Year: 2022
Journal: Diabetes
Title: GIPR Is Predominantly Localized to Nonadipocyte Cell Types Within White Adipose Tissue.
Volume: 71
Issue: 5
Pages: 1115-1127
Publication
First Author: Kivelä R
Year: 2019
Journal: Circulation
Title: Endothelial Cells Regulate Physiological Cardiomyocyte Growth via VEGFR2-Mediated Paracrine Signaling.
Volume: 139
Issue: 22
Pages: 2570-2584
Publication
First Author: Wu Y
Year: 2023
Journal: Neuron
Title: Hepatic soluble epoxide hydrolase activity regulates cerebral Aβ metabolism and the pathogenesis of Alzheimer's disease in mice.
Volume: 111
Issue: 18
Pages: 2847-2862.e10
Publication
First Author: Valussi M
Year: 2021
Journal: Sci Adv
Title: Repression of Osmr and Fgfr1 by miR-1/133a prevents cardiomyocyte dedifferentiation and cell cycle entry in the adult heart.
Volume: 7
Issue: 42
Pages: eabi6648
Publication
First Author: En A
Year: 2024
Journal: Cell Rep
Title: Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice.
Volume: 43
Issue: 6
Pages: 114284
Allele
Name: intergenic site 2; endonuclease-mediated mutation 62, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Endonuclease, Inducible, Inserted expressed sequence
Publication  
First Author: Ji YX
Year: 2016
Journal: Nat Commun
Title: The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling.
Volume: 7
Pages: 11267
Publication
First Author: Pernot M
Year: 2022
Journal: Sci Rep
Title: Decrease of Pdzrn3 is required for heart maturation and protects against heart failure.
Volume: 12
Issue: 1
Pages: 8
Publication
First Author: Swift F
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout.
Volume: 109
Issue: 10
Pages: 3997-4001
Publication  
First Author: Dadson K
Year: 2017
Journal: Sci Rep
Title: The E3 ligase Mule protects the heart against oxidative stress and mitochondrial dysfunction through Myc-dependent inactivation of Pgc-1α and Pink1.
Volume: 7
Pages: 41490
Publication
First Author: Li Y
Year: 2009
Journal: J Mol Cell Cardiol
Title: Peroxisome proliferator-activated receptor delta regulates mitofusin 2 expression in the heart.
Volume: 46
Issue: 6
Pages: 876-82
Publication
First Author: Li Y
Year: 2020
Journal: Circulation
Title: gp130 Controls Cardiomyocyte Proliferation and Heart Regeneration.
Volume: 142
Issue: 10
Pages: 967-982
Publication
First Author: Shahid M
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: BMP type I receptor ALK2 is required for angiotensin II-induced cardiac hypertrophy.
Volume: 310
Issue: 8
Pages: H984-94
Publication
First Author: Khalil H
Year: 2019
Journal: JCI Insight
Title: Cell-specific ablation of Hsp47 defines the collagen-producing cells in the injured heart
Volume: 4
Issue: 15
Pages: e128722
Publication  
First Author: Yamaguchi T
Year: 2018
Journal: Sci Signal
Title: The CCR4-NOT deadenylase complex controls Atg7-dependent cell death and heart function.
Volume: 11
Issue: 516
Publication
First Author: Martin OJ
Year: 2014
Journal: Circ Res
Title: A role for peroxisome proliferator-activated receptor γ coactivator-1 in the control of mitochondrial dynamics during postnatal cardiac growth.
Volume: 114
Issue: 4
Pages: 626-36
Publication
First Author: Goonasekera SA
Year: 2012
Journal: J Clin Invest
Title: Decreased cardiac L-type Ca²⁺ channel activity induces hypertrophy and heart failure in mice.
Volume: 122
Issue: 1
Pages: 280-90
Publication
First Author: Chen J
Year: 2013
Journal: Circ Res
Title: mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts.
Volume: 112
Issue: 12
Pages: 1557-66
Publication
First Author: Leach JP
Year: 2017
Journal: Nature
Title: Hippo pathway deficiency reverses systolic heart failure after infarction.
Volume: 550
Issue: 7675
Pages: 260-264
Publication
First Author: Kuwabara Y
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy.
Volume: 120
Issue: 19
Pages: e2213696120
Publication
First Author: Mohr ME
Year: 2024
Journal: iScience
Title: Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury.
Volume: 27
Issue: 3
Pages: 109219
Strain
Attribute String: transgenic, mutant strain, congenic
Strain
Attribute String: mutant stock, transgenic
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Strain
Attribute String: mutant strain, targeted mutation
Strain
Attribute String: mutant strain, targeted mutation
Strain
Attribute String: mutant strain, targeted mutation
Genotype
Symbol: A1cf/A1cf
Background: involves: 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: A1cf/A1cf
Background: B6.FVB(129)-A1cf/J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: A1cf/A1cf
Background: B6N(Cg)-A1cf/J
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Montañés-Agudo P
Year: 2023
Journal: Cardiovasc Res
Title: The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes.
Volume: 119
Issue: 5
Pages: 1161-1174
Publication
First Author: Li Z
Year: 2022
Journal: Int J Biol Sci
Title: Hgs Deficiency Caused Restrictive Cardiomyopathy via Disrupting Proteostasis.
Volume: 18
Issue: 5
Pages: 2018-2031
Publication
First Author: Dirkx E
Year: 2013
Journal: Nat Cell Biol
Title: Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure.
Volume: 15
Issue: 11
Pages: 1282-93
Publication  
First Author: Deng KQ
Year: 2016
Journal: Nat Commun
Title: Suppressor of IKKɛ is an essential negative regulator of pathological cardiac hypertrophy.
Volume: 7
Pages: 11432
Publication
First Author: Huang X
Year: 2021
Journal: Transgenic Res
Title: Generation and characterization of a Myh6-driven Cre knockin mouse line.
Volume: 30
Issue: 6
Pages: 821-835
Publication  
First Author: Díaz-Trelles R
Year: 2016
Journal: Nat Commun
Title: Notch-independent RBPJ controls angiogenesis in the adult heart.
Volume: 7
Pages: 12088
Publication
First Author: Gordts PL
Year: 2016
Journal: J Clin Invest
Title: ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors.
Volume: 126
Issue: 8
Pages: 2855-66
Publication
First Author: Lavine KJ
Year: 2008
Journal: J Clin Invest
Title: Hedgehog signaling is critical for maintenance of the adult coronary vasculature in mice.
Volume: 118
Issue: 7
Pages: 2404-14
Publication  
First Author: Heck-Swain KL
Year: 2022
Journal: Front Cardiovasc Med
Title: Myeloid hypoxia-inducible factor HIF1A provides cardio-protection during ischemia and reperfusion via induction of netrin-1.
Volume: 9
Pages: 970415
Publication
First Author: el Azzouzi H
Year: 2013
Journal: Cell Metab
Title: The hypoxia-inducible microRNA cluster miR-199a∼214 targets myocardial PPARδ and impairs mitochondrial fatty acid oxidation.
Volume: 18
Issue: 3
Pages: 341-54
Publication
First Author: Song S
Year: 2022
Journal: Circulation
Title: Myocardial Rev-erb-Mediated Diurnal Metabolic Rhythm and Obesity Paradox.
Volume: 145
Issue: 6
Pages: 448-464
Publication
First Author: Fernandez-Caggiano M
Year: 2020
Journal: Nat Metab
Title: Mitochondrial pyruvate carrier abundance mediates pathological cardiac hypertrophy.
Volume: 2
Issue: 11
Pages: 1223-1231
Publication
First Author: Heallen T
Year: 2013
Journal: Development
Title: Hippo signaling impedes adult heart regeneration.
Volume: 140
Issue: 23
Pages: 4683-90
Publication
First Author: Ma X
Year: 2022
Journal: JACC Basic Transl Sci
Title: TRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis.
Volume: 7
Issue: 3
Pages: 223-243
Publication
First Author: Vanderlaan RD
Year: 2011
Journal: Circ Res
Title: The ShcA phosphotyrosine docking protein uses distinct mechanisms to regulate myocyte and global heart function.
Volume: 108
Issue: 2
Pages: 184-93
Publication
First Author: Galloway CA
Year: 2010
Journal: Biochim Biophys Acta
Title: Metabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes.
Volume: 1802
Issue: 11
Pages: 976-85
Publication
First Author: Spitler KM
Year: 2017
Journal: Am J Physiol Heart Circ Physiol
Title: Cardiac Med1 deletion promotes early lethality, cardiac remodeling, and transcriptional reprogramming.
Volume: 312
Issue: 4
Pages: H768-H780
Publication  
First Author: Ruan W
Year: 2023
Journal: JCI Insight
Title: Targeting myocardial equilibrative nucleoside transporter ENT1 provides cardioprotection by enhancing myeloid Adora2b signaling.
Volume: 8
Issue: 11
Publication  
First Author: Liang Y
Year: 2021
Journal: J Clin Invest
Title: Desmosomal COP9 regulates proteome degradation in arrhythmogenic right ventricular dysplasia/cardiomyopathy.
Volume: 131
Issue: 11
Publication
First Author: Tao G
Year: 2016
Journal: Nature
Title: Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury.
Volume: 534
Issue: 7605
Pages: 119-23
Publication  
First Author: Willis MS
Year: 2017
Journal: J Mol Cell Cardiol
Title: BRG1 and BRM function antagonistically with c-MYC in adult cardiomyocytes to regulate conduction and contractility.
Volume: 105
Pages: 99-109
Protein Domain
Type: Domain
Description: APOBEC1 complementation factor (A1CF or ACF) and APOBEC1 (an RNA-binding cytidine deaminase) form the apolipoprotein B (apoB) mRNA editing enzyme complex, which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in apoB mRNA [, ]. APOBEC1 alone induces nonsense-mediated decay (NMD), while the APOBEC1-ACF complex edits and remains associated with the edited RNA to protect it from NMD []. ACF has been shown to bind with high affinity to single-stranded but not double-stranded apoB mRNA [].A1CF contains three RNA recognition motifs (RRMs) and a C-terminal double-stranded RNA binding motif (DSRM). This entry represents the DSRM of A1CF.
Publication  
First Author: Tannous C
Year: 2021
Journal: Int J Mol Sci
Title: NMRK2 Gene Is Upregulated in Dilated Cardiomyopathy and Required for Cardiac Function and NAD Levels during Aging.
Volume: 22
Issue: 7
Publication
First Author: Wu SP
Year: 2013
Journal: Dev Cell
Title: Atrial identity is determined by a COUP-TFII regulatory network.
Volume: 25
Issue: 4
Pages: 417-26
Publication
First Author: Huang W
Year: 2018
Journal: Nat Commun
Title: Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration.
Volume: 9
Issue: 1
Pages: 700
Publication
First Author: Yuan B
Year: 2014
Journal: Am J Pathol
Title: A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice.
Volume: 184
Issue: 7
Pages: 1967-80
Publication
First Author: Wu T
Year: 2022
Journal: Circulation
Title: PRDM16 Is a Compact Myocardium-Enriched Transcription Factor Required to Maintain Compact Myocardial Cardiomyocyte Identity in Left Ventricle.
Volume: 145
Issue: 8
Pages: 586-602
Publication
First Author: Wei W
Year: 2023
Journal: Cell Metab
Title: Organism-wide, cell-type-specific secretome mapping of exercise training in mice.
Volume: 35
Issue: 7
Pages: 1261-1279.e11
Publication
First Author: Nicolás-Ávila JA
Year: 2020
Journal: Cell
Title: A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart.
Volume: 183
Issue: 1
Pages: 94-109.e23
Strain
Attribute String: mutant strain, targeted mutation, transgenic, congenic
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Genotype
Symbol: A1cf/A1cf<+>
Background: involves: 129S/Sv * C57BL/6 * FVB/N
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: A1cf/? Tg(CAG-cat,-Trim8)4Holi/?
Background: involves: C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: A1cf/A1cf<+>
Background: B6N(Cg)-A1cf/J
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Boogerd CJ
Year: 2023
Journal: Nat Commun
Title: Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation.
Volume: 14
Issue: 1
Pages: 4716
Publication
First Author: Tan C
Year: 2021
Journal: PLoS Genet
Title: Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network.
Volume: 17
Issue: 9
Pages: e1009785
Publication
First Author: Tian Y
Year: 2015
Journal: Sci Transl Med
Title: A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice.
Volume: 7
Issue: 279
Pages: 279ra38
Publication
First Author: Li L
Year: 2014
Journal: Circulation
Title: Transforming growth factor β-activated kinase 1 signaling pathway critically regulates myocardial survival and remodeling.
Volume: 130
Issue: 24
Pages: 2162-72
Publication
First Author: Lei Y
Year: 2023
Journal: Cell
Title: Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity.
Volume: 186
Issue: 14
Pages: 3013-3032.e22
Publication
First Author: Moga MA
Year: 2008
Journal: J Mol Cell Cardiol
Title: Genetic approaches for changing the heart and dissecting complex syndromes.
Volume: 45
Issue: 2
Pages: 148-55
Publication
First Author: Papanicolaou KN
Year: 2012
Journal: Circ Res
Title: Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart.
Volume: 111
Issue: 8
Pages: 1012-26