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Search results 801 to 900 out of 926 for Atf4

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Type Details Score
Publication
First Author: Zhang M
Year: 2017
Journal: FEBS Lett
Title: NDRG2 acts as a PERK co-factor to facilitate PERK branch and ERS-induced cell death.
Volume: 591
Issue: 21
Pages: 3670-3681
Publication
First Author: Zhou J
Year: 2018
Journal: Mol Cell
Title: N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response.
Volume: 69
Issue: 4
Pages: 636-647.e7
Publication
First Author: Kato Y
Year: 1999
Journal: Mol Cell Endocrinol
Title: Presence of activating transcription factor 4 (ATF4) in the porcine anterior pituitary.
Volume: 154
Issue: 1-2
Pages: 151-9
Publication
First Author: Clavarino G
Year: 2012
Journal: PLoS Pathog
Title: Induction of GADD34 is necessary for dsRNA-dependent interferon-β production and participates in the control of Chikungunya virus infection.
Volume: 8
Issue: 5
Pages: e1002708
Publication
First Author: Liu J
Year: 2015
Journal: Am J Physiol Cell Physiol
Title: Impact of ER stress-regulated ATF4/p16 signaling on the premature senescence of renal tubular epithelial cells in diabetic nephropathy.
Volume: 308
Issue: 8
Pages: C621-30
Publication
First Author: Martina JA
Year: 2016
Journal: EMBO J
Title: TFEB and TFE3 are novel components of the integrated stress response.
Volume: 35
Issue: 5
Pages: 479-95
Publication      
First Author: Yang G
Year: 2024
Journal: Neuron
Title: Spliceosomal GTPase Eftud2 deficiency-triggered ferroptosis leads to Purkinje cell degeneration.
Publication
First Author: Podust LM
Year: 2001
Journal: J Biol Chem
Title: Crystal structure of the CCAAT box/enhancer-binding protein beta activating transcription factor-4 basic leucine zipper heterodimer in the absence of DNA.
Volume: 276
Issue: 1
Pages: 505-13
Publication
First Author: Costa-Mattioli M
Year: 2005
Journal: Nature
Title: Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2.
Volume: 436
Issue: 7054
Pages: 1166-73
Publication
First Author: Carpio MA
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: BCL-2 family member BOK promotes apoptosis in response to endoplasmic reticulum stress.
Volume: 112
Issue: 23
Pages: 7201-6
Publication
First Author: Latreille M
Year: 2006
Journal: J Biol Chem
Title: Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress.
Volume: 281
Issue: 36
Pages: 26633-44
Publication
First Author: Galichon P
Year: 2017
Journal: J Am Soc Nephrol
Title: Stress Response Gene Nupr1 Alleviates Cyclosporin A Nephrotoxicity In Vivo.
Volume: 28
Issue: 2
Pages: 545-556
Publication
First Author: Kim MH
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Hepatic ZIP14-mediated zinc transport is required for adaptation to endoplasmic reticulum stress.
Volume: 114
Issue: 29
Pages: E5805-E5814
Publication
First Author: Pereira CM
Year: 2005
Journal: J Biol Chem
Title: IMPACT, a protein preferentially expressed in the mouse brain, binds GCN1 and inhibits GCN2 activation.
Volume: 280
Issue: 31
Pages: 28316-23
Publication
First Author: Yu VW
Year: 2009
Journal: J Cell Biochem
Title: FIAT inhibition increases osteoblast activity by modulating Atf4-dependent functions.
Volume: 106
Issue: 1
Pages: 186-92
Publication
First Author: Isaac R
Year: 2017
Journal: Cell Death Differ
Title: TM7SF3, a novel p53-regulated homeostatic factor, attenuates cellular stress and the subsequent induction of the unfolded protein response.
Volume: 24
Issue: 1
Pages: 132-143
Publication
First Author: Nerlich A
Year: 2015
Journal: Biochim Biophys Acta
Title: C/EBPβ is a transcriptional key regulator of IL-36α in murine macrophages.
Volume: 1849
Issue: 8
Pages: 966-78
Publication
First Author: Hayakawa M
Year: 2015
Journal: Neurobiol Aging
Title: Quercetin reduces eIF2α phosphorylation by GADD34 induction.
Volume: 36
Issue: 9
Pages: 2509-18
Publication
First Author: Yang S
Year: 2024
Journal: Exp Mol Med
Title: Advanced glycation end products promote meniscal calcification by activating the mTOR-ATF4 positive feedback loop.
Volume: 56
Issue: 3
Pages: 630-645
Publication
First Author: Agergaard J
Year: 2021
Journal: Sci Rep
Title: Impaired skeletal muscle hypertrophy signaling and amino acid deprivation response in Apoe knockout mice with an unhealthy lipoprotein distribution.
Volume: 11
Issue: 1
Pages: 16423
Publication  
First Author: Sain Basu D
Year: 2022
Journal: J Cell Sci
Title: FMRP protects the lung from xenobiotic stress by facilitating the integrated stress response.
Volume: 135
Issue: 9
Publication
First Author: Berthoud VM
Year: 2016
Journal: J Biol Chem
Title: The Cataract-linked Mutant Connexin50D47A Causes Endoplasmic Reticulum Stress in Mouse Lenses.
Volume: 291
Issue: 34
Pages: 17569-78
Publication
First Author: Cai Q
Year: 2010
Journal: Am J Physiol Renal Physiol
Title: Vasopressin increases expression of UT-A1, UT-A3, and ER chaperone GRP78 in the renal medulla of mice with a urinary concentrating defect.
Volume: 299
Issue: 4
Pages: F712-9
Publication
First Author: Takahashi K
Year: 2014
Journal: J Biol Chem
Title: Impaired oxidative endoplasmic reticulum stress response caused by deficiency of thyroid hormone receptor α.
Volume: 289
Issue: 18
Pages: 12485-93
Publication
First Author: Kuroda R
Year: 2021
Journal: PLoS One
Title: Loss of mitochondrial transcription factor A in neural stem cells leads to immature brain development and triggers the activation of the integral stress response in vivo.
Volume: 16
Issue: 7
Pages: e0255355
Publication  
First Author: Alapure BV
Year: 2012
Journal: Exp Eye Res
Title: The unfolded protein response is activated in connexin 50 mutant mouse lenses.
Volume: 102
Pages: 28-37
Publication  
First Author: Lehman SL
Year: 2015
Journal: Sci Rep
Title: Signaling through alternative Integrated Stress Response pathways compensates for GCN2 loss in a mouse model of soft tissue sarcoma.
Volume: 5
Pages: 11781
Publication
First Author: Delitsikou V
Year: 2020
Journal: FASEB J
Title: Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress.
Volume: 34
Issue: 2
Pages: 2087-2104
Publication
First Author: Shimizu M
Year: 2013
Journal: Biochem J
Title: FGF19 (fibroblast growth factor 19) as a novel target gene for activating transcription factor 4 in response to endoplasmic reticulum stress.
Volume: 450
Issue: 1
Pages: 221-9
Publication  
First Author: Yu M
Year: 2015
Journal: Exp Eye Res
Title: Deficiency of CC chemokine ligand 2 and decay-accelerating factor causes retinal degeneration in mice.
Volume: 138
Pages: 126-33
Publication
First Author: Guo W
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: Fatty Acids Inhibit LAMP2-Mediated Autophagy Flux via Activating ER Stress Pathway in Alcohol-Related Liver Disease.
Volume: 12
Issue: 5
Pages: 1599-1615
Publication
First Author: Agouni A
Year: 2011
Journal: Biochem J
Title: Liver-specific deletion of protein tyrosine phosphatase (PTP) 1B improves obesity- and pharmacologically induced endoplasmic reticulum stress.
Volume: 438
Issue: 2
Pages: 369-78
Publication
First Author: Devi L
Year: 2014
Journal: Neurobiol Aging
Title: PERK mediates eIF2α phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease.
Volume: 35
Issue: 10
Pages: 2272-81
Publication
First Author: Blais JD
Year: 2004
Journal: Mol Cell Biol
Title: Activating transcription factor 4 is translationally regulated by hypoxic stress.
Volume: 24
Issue: 17
Pages: 7469-82
Publication
First Author: Ghosh R
Year: 2010
Journal: PLoS One
Title: Transcriptional regulation of VEGF-A by the unfolded protein response pathway.
Volume: 5
Issue: 3
Pages: e9575
Publication
First Author: Kovacs WJ
Year: 2009
Journal: J Biol Chem
Title: Peroxisome deficiency causes a complex phenotype because of hepatic SREBP/Insig dysregulation associated with endoplasmic reticulum stress.
Volume: 284
Issue: 11
Pages: 7232-45
Publication
First Author: Li Y
Year: 2008
Journal: J Biol Chem
Title: Differential control of the CCAAT/enhancer-binding protein beta (C/EBPbeta) products liver-enriched transcriptional activating protein (LAP) and liver-enriched transcriptional inhibitory protein (LIP) and the regulation of gene expression during the response to endoplasmic reticulum stress.
Volume: 283
Issue: 33
Pages: 22443-56
Publication
First Author: Marlin E
Year: 2024
Journal: Br J Pharmacol
Title: Pharmacological inhibition of the integrated stress response accelerates disease progression in an amyotrophic lateral sclerosis mouse model.
Volume: 181
Issue: 3
Pages: 495-508
Publication  
First Author: Briggs DI
Year: 2017
Journal: eNeuro
Title: Role of Endoplasmic Reticulum Stress in Learning and Memory Impairment and Alzheimer's Disease-Like Neuropathology in the PS19 and APPSwe Mouse Models of Tauopathy and Amyloidosis.
Volume: 4
Issue: 4
Publication
First Author: Jonsson WO
Year: 2022
Journal: FASEB J
Title: Activation and execution of the hepatic integrated stress response by dietary essential amino acid deprivation is amino acid specific.
Volume: 36
Issue: 7
Pages: e22396
Publication  
First Author: Sala E
Year: 2021
Journal: Front Immunol
Title: CDK11 Promotes Cytokine-Induced Apoptosis in Pancreatic Beta Cells Independently of Glucose Concentration and Is Regulated by Inflammation in the NOD Mouse Model.
Volume: 12
Pages: 634797
Publication
First Author: Wei GZ
Year: 2021
Journal: PLoS One
Title: Hypoxia-inducible factor prolyl hydroxylase domain (PHD) inhibition after contusive spinal cord injury does not improve locomotor recovery.
Volume: 16
Issue: 4
Pages: e0249591
Publication  
First Author: Busby T
Year: 2021
Journal: Front Endocrinol (Lausanne)
Title: Baf45a Mediated Chromatin Remodeling Promotes Transcriptional Activation for Osteogenesis and Odontogenesis.
Volume: 12
Pages: 763392
Publication
First Author: Liu H
Year: 2014
Journal: Mol Cell Biol
Title: GCN2-dependent metabolic stress is essential for endotoxemic cytokine induction and pathology.
Volume: 34
Issue: 3
Pages: 428-38
Publication
First Author: Guridi M
Year: 2015
Journal: Sci Signal
Title: Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21.
Volume: 8
Issue: 402
Pages: ra113
Publication  
First Author: Guo Y
Year: 2023
Journal: Int J Mol Sci
Title: Large HBV Surface Protein-Induced Unfolded Protein Response Dynamically Regulates p27 Degradation in Hepatocellular Carcinoma Progression.
Volume: 24
Issue: 18
Publication
First Author: Devi L
Year: 2013
Journal: PLoS One
Title: Deletion of the eIF2α Kinase GCN2 fails to rescue the memory decline associated with Alzheimer's disease.
Volume: 8
Issue: 10
Pages: e77335
Publication
First Author: Sun ZG
Year: 2020
Journal: Int Heart J
Title: Exercise Preconditioning Protects against Acute Cardiac Injury Induced by Lipopolysaccharide Through General Control Nonderepressible 2 Kinase.
Volume: 61
Issue: 1
Pages: 138-144
Publication
First Author: Ishikawa M
Year: 2024
Journal: Nature
Title: Bone marrow plasma cells require P2RX4 to sense extracellular ATP.
Volume: 626
Issue: 8001
Pages: 1102-1107
Publication  
First Author: Krawczyk KK
Year: 2016
Journal: Sci Rep
Title: Assessing the contribution of thrombospondin-4 induction and ATF6α activation to endoplasmic reticulum expansion and phenotypic modulation in bladder outlet obstruction.
Volume: 6
Pages: 32449
Publication
First Author: Bettaieb A
Year: 2012
Journal: PLoS One
Title: Protein tyrosine phosphatase 1B deficiency potentiates PERK/eIF2α signaling in brown adipocytes.
Volume: 7
Issue: 4
Pages: e34412
Publication
First Author: Palko SI
Year: 2024
Journal: Glia
Title: ER-stress response in retinal Müller glia occurs significantly earlier than amyloid pathology in the Alzheimer's mouse brain and retina.
Volume: 72
Issue: 6
Pages: 1067-1081
Publication    
First Author: Gorrell L
Year: 2022
Journal: Adv Sci (Weinh)
Title: ER, Mitochondria, and ISR Regulation by mt-HSP70 and ATF5 upon Procollagen Misfolding in Osteoblasts.
Pages: e2201273
Publication  
First Author: Tominaga T
Year: 2017
Journal: Neurosci Lett
Title: Sequestosome 1 (SQSTM1/p62) maintains protein folding capacity under endoplasmic reticulum stress in mouse hypothalamic organotypic culture.
Volume: 656
Pages: 103-107
Publication      
First Author: Shiozaki Y
Year: 2018
Journal: J Biol Chem
Title: The CDK 9-cyclin T1 complex mediates saturated fatty acid-induced vascular calcification by inducing expression of the transcription factor CHOP.
Publication  
First Author: Mizumoto T
Year: 2022
Journal: Cells
Title: SIRT7 Deficiency Protects against Aging-Associated Glucose Intolerance and Extends Lifespan in Male Mice.
Volume: 11
Issue: 22
Publication
First Author: Yao Y
Year: 2017
Journal: Nat Commun
Title: A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure.
Volume: 8
Issue: 1
Pages: 133
Publication
First Author: Chang PC
Year: 2015
Journal: Biochim Biophys Acta
Title: TRC8 downregulation contributes to the development of non-alcoholic steatohepatitis by exacerbating hepatic endoplasmic reticulum stress.
Volume: 1852
Issue: 11
Pages: 2339-51
Publication
First Author: Santos CX
Year: 2016
Journal: EMBO J
Title: Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signaling.
Volume: 35
Issue: 3
Pages: 319-34
Publication
First Author: Juliana CA
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: ATF5 regulates β-cell survival during stress.
Volume: 114
Issue: 6
Pages: 1341-1346
Publication
First Author: Örd D
Year: 2016
Journal: Biochim Biophys Acta
Title: TRIB3 increases cell resistance to arsenite toxicity by limiting the expression of the glutathione-degrading enzyme CHAC1.
Volume: 1863
Issue: 11
Pages: 2668-2680
Publication  
First Author: Brooks AC
Year: 2014
Journal: J Mol Cell Cardiol
Title: Endoplasmic reticulum stress-dependent activation of ATF3 mediates the late phase of ischemic preconditioning.
Volume: 76
Pages: 138-47
Publication
First Author: Hekmatnejad B
Year: 2017
Journal: Endocrinology
Title: FIAT Deletion Increases Bone Mass But Does Not Prevent High-Fat-Diet-Induced Metabolic Complications.
Volume: 158
Issue: 2
Pages: 264-276
Publication
First Author: Fujita Y
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Differentiated embryo chondrocyte 1 (DEC1) is a novel negative regulator of hepatic fibroblast growth factor 21 (FGF21) in aging mice.
Volume: 469
Issue: 3
Pages: 477-82
Publication
First Author: Tobias ES
Year: 2024
Journal: Endocrine
Title: SEC31A may be associated with pituitary hormone deficiency and gonadal dysgenesis.
Volume: 84
Issue: 2
Pages: 345-349
Publication
First Author: Ding W
Year: 2023
Journal: FASEB J
Title: Hu'po Anshen decoction promotes fracture healing in mice with traumatic brain injury through BMP2-COX2-ATF4 signaling pathway.
Volume: 37
Issue: 6
Pages: e22952
Publication
First Author: Tresky R
Year: 2024
Journal: Nucleic Acids Res
Title: TRMT10A dysfunction perturbs codon translation of initiator methionine and glutamine and impairs brain functions in mice.
Volume: 52
Issue: 15
Pages: 9230-9246
Publication  
First Author: Kawakubo-Yasukochi T
Year: 2021
Journal: Mol Metab
Title: Hepatic glycogenolysis is determined by maternal high-calorie diet via methylation of Pygl and it is modified by oteocalcin administration in mice.
Volume: 54
Pages: 101360
Publication
First Author: Ito D
Year: 2004
Journal: Mol Cell Biol
Title: Characterization of stanniocalcin 2, a novel target of the mammalian unfolded protein response with cytoprotective properties.
Volume: 24
Issue: 21
Pages: 9456-69
Publication
First Author: Wang Y
Year: 2012
Journal: Cancer Res
Title: The unfolded protein response induces the angiogenic switch in human tumor cells through the PERK/ATF4 pathway.
Volume: 72
Issue: 20
Pages: 5396-406
Publication
First Author: Thiaville MM
Year: 2008
Journal: J Biol Chem
Title: MEK signaling is required for phosphorylation of eIF2alpha following amino acid limitation of HepG2 human hepatoma cells.
Volume: 283
Issue: 16
Pages: 10848-57
Publication
First Author: Hull RL
Year: 2009
Journal: Diabetologia
Title: Amyloid formation in human IAPP transgenic mouse islets and pancreas, and human pancreas, is not associated with endoplasmic reticulum stress.
Volume: 52
Issue: 6
Pages: 1102-11
Publication
First Author: Felkin LE
Year: 2011
Journal: Circulation
Title: Calcineurin splicing variant calcineurin Aβ1 improves cardiac function after myocardial infarction without inducing hypertrophy.
Volume: 123
Issue: 24
Pages: 2838-47
Publication
First Author: Wei W
Year: 2012
Journal: J Neurosci
Title: p300/CBP-associated factor selectively regulates the extinction of conditioned fear.
Volume: 32
Issue: 35
Pages: 11930-41
Publication
First Author: Zhou C
Year: 2017
Journal: Leukemia
Title: JUN is a key transcriptional regulator of the unfolded protein response in acute myeloid leukemia.
Volume: 31
Issue: 5
Pages: 1196-1205
Publication
First Author: Jasani N
Year: 2025
Journal: Cancer Res
Title: PHGDH Induction by MAPK Is Essential for Melanoma Formation and Creates an Actionable Metabolic Vulnerability.
Volume: 85
Issue: 2
Pages: 314-328
Publication
First Author: Shan J
Year: 2016
Journal: Nucleic Acids Res
Title: The C/ebp-Atf response element (CARE) location reveals two distinct Atf4-dependent, elongation-mediated mechanisms for transcriptional induction of aminoacyl-tRNA synthetase genes in response to amino acid limitation.
Volume: 44
Issue: 20
Pages: 9719-9732
Publication
First Author: Lim JKM
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance.
Volume: 116
Issue: 19
Pages: 9433-9442
Publication
First Author: Kang SH
Year: 2019
Journal: Ann Hematol
Title: BOK promotes erythropoiesis in a mouse model of myelodysplastic syndrome.
Volume: 98
Issue: 9
Pages: 2089-2096
Publication
First Author: Feng X
Year: 2020
Journal: EMBO J
Title: UHMK1 promotes gastric cancer progression through reprogramming nucleotide metabolism.
Volume: 39
Issue: 5
Pages: e102541
Publication
First Author: Ikegami K
Year: 2020
Journal: Biochem Biophys Res Commun
Title: cAMP response element induces Per1 in vivo.
Volume: 531
Issue: 4
Pages: 515-521
Publication
First Author: Xu X
Year: 2018
Journal: Hepatology
Title: Preemptive Activation of the Integrated Stress Response Protects Mice From Diet-Induced Obesity and Insulin Resistance by Fibroblast Growth Factor 21 Induction.
Volume: 68
Issue: 6
Pages: 2167-2181
Publication
First Author: Na Y
Year: 2023
Journal: Oncogene
Title: Runx1/3-driven adaptive endoplasmic reticulum stress pathways contribute to neurofibromagenesis.
Volume: 42
Issue: 13
Pages: 1038-1047
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Dedhia PH
Year: 2010
Journal: Blood
Title: Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia.
Volume: 116
Issue: 8
Pages: 1321-8
Protein
Organism: Mus musculus/domesticus
Length: 795  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 831  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 866  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 958  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 842  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 958  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 900  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 826  
Fragment?: true
Publication
First Author: Chen JJ
Year: 2019
Journal: Blood
Title: Heme-regulated eIF2α kinase in erythropoiesis and hemoglobinopathies.
Volume: 134
Issue: 20
Pages: 1697-1707
Publication
First Author: Gunn TM
Year: 2019
Journal: Mamm Genome
Title: Chronic and age-dependent effects of the spongiform neurodegeneration-associated MGRN1 E3 ubiquitin ligase on mitochondrial homeostasis.
Volume: 30
Issue: 5-6
Pages: 151-165
Publication  
First Author: Lu Y
Year: 2023
Journal: Front Immunol
Title: ER stress mediates Angiotensin II-augmented innate immunity memory and facilitates distinct susceptibilities of thoracic from abdominal aorta to aneurysm development.
Volume: 14
Pages: 1268916
Publication
First Author: Tang CY
Year: 2021
Journal: PLoS Genet
Title: Runx1 is a central regulator of osteogenesis for bone homeostasis by orchestrating BMP and WNT signaling pathways.
Volume: 17
Issue: 1
Pages: e1009233
Publication  
First Author: Felszeghy S
Year: 2019
Journal: Redox Biol
Title: Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration.
Volume: 20
Pages: 1-12
Publication
First Author: Chen W
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Cbfβ deletion in mice recapitulates cleidocranial dysplasia and reveals multiple functions of Cbfβ required for skeletal development.
Volume: 111
Issue: 23
Pages: 8482-7