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Search results 801 to 900 out of 4306 for C3

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Type Details Score
Publication
18687868 | -
First Author: Haspel N
Year: 2008
Journal: Protein Sci
Title: Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d.
Volume: 17
Issue: 11
Pages: 1894-906
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Publication
21055811 | -
First Author: Clark EA
Year: 2011
Journal: Mol Immunol
Title: A structural basis for Staphylococcal complement subversion: X-ray structure of the complement-binding domain of Staphylococcus aureus protein Sbi in complex with ligand C3d.
Volume: 48
Issue: 4
Pages: 452-62
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Protein Domain
IPR041909 | Sbi_C3_db_domIV
Type: Homologous_superfamily
Description: This superfamily includes the immunoglobulin-binding protein Sbi domain IV (Sbi-IV) which binds the central complement protein C3. Sbi-IV interacts with Sbi-III to induce a consumption of complement via alternative pathway activation []. When not interacting with Sbi-III, Sbi-IV inhibits the alternative pathway without complement consumption. Sbi-IV structurally comprises a three-helix bundle [].Sbi-IV is similar to Efb-C and Ehp [, , ]. Sbi-IV binds to the thioester-containing domain of native C3. The interaction between Sbi-IV and C3, in the presence of domain III, results in the formation of a covalent Sbi-III-IV-C3 adduct followed by futile fluid phase consumption of C3 [].
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Protein
H3BKW9
Organism: Mus musculus/domesticus
Length: 185  
Fragment?: true
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Publication
12756295 | J:83623
First Author: Yadav N
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Specific protein methylation defects and gene expression perturbations in coactivator-associated arginine methyltransferase 1-deficient mice.
Volume: 100
Issue: 11
Pages: 6464-8
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Publication
9244432 | J:42075
First Author: Sobek-Klocke I
Year: 1997
Journal: Genomics
Title: The human gene ZFP161 on 18p11.21-pter encodes a putative c-myc repressor and is homologous to murine Zfp161 (Chr 17) and Zfp161-rs1 (X Chr)
Volume: 43
Issue: 2
Pages: 156-64
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Publication
17322907 | J:279795
First Author: Chen NJ
Year: 2007
Journal: Nature
Title: C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a.
Volume: 446
Issue: 7132
Pages: 203-7
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Publication
11360154 | J:69140
First Author: Saleh J
Year: 2001
Journal: Int J Obes Relat Metab Disord
Title: Acylation stimulating protein (ASP) acute effects on postprandial lipemia and food intake in rodents.
Volume: 25
Issue: 5
Pages: 705-13
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Publication
18820683 | J:143335
First Author: Markiewski MM
Year: 2008
Journal: Nat Immunol
Title: Modulation of the antitumor immune response by complement.
Volume: 9
Issue: 11
Pages: 1225-35
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Publication
17237432 | J:143636
First Author: Thurman JM
Year: 2007
Journal: J Immunol
Title: C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion.
Volume: 178
Issue: 3
Pages: 1819-28
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Publication
22422887 | J:184063
First Author: Galvan MD
Year: 2012
Journal: J Immunol
Title: Complement component C1q regulates macrophage expression of Mer tyrosine kinase to promote clearance of apoptotic cells.
Volume: 188
Issue: 8
Pages: 3716-23
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Publication
22184721 | J:180773
First Author: DeAngelis RA
Year: 2012
Journal: J Immunol
Title: A complement-IL-4 regulatory circuit controls liver regeneration.
Volume: 188
Issue: 2
Pages: 641-8
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Publication
18063050 | J:131606
First Author: Hollmann TJ
Year: 2008
Journal: Mol Immunol
Title: Disruption of the C5a receptor gene increases resistance to acute Gram-negative bacteremia and endotoxic shock: opposing roles of C3a and C5a.
Volume: 45
Issue: 7
Pages: 1907-15
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Publication
2002550 | J:11032
First Author: Brownstein DG
Year: 1991
Journal: J Virol
Title: Chromosomal locations and gonadal dependence of genes that mediate resistance to ectromelia (mousepox) virus-induced mortality.
Volume: 65
Issue: 4
Pages: 1946-51
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Publication
9434950 | J:41603
First Author: Torrey T
Year: 1998
Journal: Mamm Genome
Title: Cloning, expression and genetic mapping of the mouse SH3 domain protein, SH3D2B.
Volume: 9
Issue: 1
Pages: 74-5
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Publication
24470395 | J:210680
First Author: Rudnicki A
Year: 2014
Journal: Hum Mol Genet
Title: microRNA-224 regulates Pentraxin 3, a component of the humoral arm of innate immunity, in inner ear inflammation.
Volume: 23
Issue: 12
Pages: 3138-46
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UniProt Feature
UniProt Feature
Begin: 671
Description: Complement C3 alpha chain
Type: chain
End: 1663
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UniProt Feature
UniProt Feature
Begin: 748
Description: Cleavage; by C3 convertase
Type: site
End: 749
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UniProt Feature
UniProt Feature
Begin: 25
Description: Complement C3 beta chain
Type: chain
End: 666
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Strain
MGI:7433249 | C57BL/6 x C3
Attribute String: Not specified
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Publication
7926807 | J:20871
First Author: Treuner M
Year: 1994
Journal: Gene
Title: Cloning and characterization of the mouse gene encoding mammary-derived growth inhibitor/heart-fatty acid-binding protein.
Volume: 147
Issue: 2
Pages: 237-42
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Publication
9169125 | J:37740
First Author: Lin HH
Year: 1997
Journal: Genomics
Title: Identification and characterization of a seven transmembrane hormone receptor using differential display.
Volume: 41
Issue: 3
Pages: 301-8
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Publication
2885372 | J:8762
First Author: Gardner SM
Year: 1987
Journal: J Immunol
Title: Mouse lymphotoxin and tumor necrosis factor: structural analysis of the cloned genes, physical linkage, and chromosomal position.
Volume: 139
Issue: 2
Pages: 476-83
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Publication
16849485 | J:137976
First Author: Jawdat DM
Year: 2006
Journal: J Immunol
Title: Mast cells have a pivotal role in TNF-independent lymph node hypertrophy and the mobilization of Langerhans cells in response to bacterial peptidoglycan.
Volume: 177
Issue: 3
Pages: 1755-62
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Publication
16177324 | J:104212
First Author: Wolfe DN
Year: 2005
Journal: Infect Immun
Title: Clearance of Bordetella parapertussis from the lower respiratory tract requires humoral and cellular immunity.
Volume: 73
Issue: 10
Pages: 6508-13
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Publication
16301658 | J:122156
First Author: Kirimanjeswara GS
Year: 2005
Journal: J Immunol
Title: The complex mechanism of antibody-mediated clearance of Bordetella from the lungs requires TLR4.
Volume: 175
Issue: 11
Pages: 7504-11
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Publication
19112490 | J:162201
First Author: Moulton EA
Year: 2008
Journal: PLoS Pathog
Title: Surviving mousepox infection requires the complement system.
Volume: 4
Issue: 12
Pages: e1000249
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Publication
21943708 | J:177350
First Author: Banda NK
Year: 2011
Journal: Mol Immunol
Title: Mechanisms of mannose-binding lectin-associated serine proteases-1/3 activation of the alternative pathway of complement.
Volume: 49
Issue: 1-2
Pages: 281-9
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Publication
27041467 | J:233754
First Author: Broders-Bondon F
Year: 2016
Journal: Dev Biol
Title: Control of the collective migration of enteric neural crest cells by the Complement anaphylatoxin C3a and N-cadherin.
Volume: 414
Issue: 1
Pages: 85-99
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Publication
27644882 | J:239128
First Author: Ji S
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Increased a-series gangliosides positively regulate leptin/Ob receptor-mediated signals in hypothalamus of GD3 synthase-deficient mice.
Volume: 479
Issue: 3
Pages: 453-460
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Publication
3003932 | J:8183
First Author: Hilkens J
Year: 1986
Journal: Somat Cell Mol Genet
Title: Genetic mapping of Pim-1 putative oncogene to mouse chromosome 17.
Volume: 12
Issue: 1
Pages: 81-8
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Publication
3356450 | J:9123
First Author: Lyon MF
Year: 1988
Journal: Immunogenetics
Title: Extent of the mouse t complex and its inversions shown by in situ hybridization.
Volume: 27
Issue: 5
Pages: 375-82
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Publication
1970332 | J:10445
First Author: Sertić J
Year: 1990
Journal: Genomics
Title: Mapping of the L-methylmalonyl-CoA mutase gene to mouse chromosome 17.
Volume: 6
Issue: 3
Pages: 560-4
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Publication
1774067 | J:11582
First Author: Li XY
Year: 1991
Journal: Genomics
Title: One subunit of the transcription factor NF-Y maps close to the major histocompatibility complex in murine and human chromosomes.
Volume: 11
Issue: 3
Pages: 630-4
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Publication
1347473 | J:1607
First Author: Sertic J
Year: 1992
Journal: Mamm Genome
Title: Mapping of six DNA markers on mouse chromosome 17.
Volume: 2
Issue: 2
Pages: 138-42
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Publication
1559701 | J:2290
First Author: Johnson KR
Year: 1992
Journal: Genomics
Title: Chromosomal localization of the murine gene and two related sequences encoding high-mobility-group I and Y proteins.
Volume: 12
Issue: 3
Pages: 503-9
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Publication
8227050 | J:15863
First Author: Yan H
Year: 1993
Journal: J Biol Chem
Title: A novel receptor tyrosine phosphatase-sigma that is highly expressed in the nervous system.
Volume: 268
Issue: 33
Pages: 24880-6
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Publication
7601475 | J:24217
First Author: Khan AS
Year: 1995
Journal: Genomics
Title: Rat phenol-preferring sulfotransferase genes (Stp and Stp2): localization to mouse chromosomes 7 and 17.
Volume: 26
Issue: 2
Pages: 417-9
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Publication
8672143 | J:34468
First Author: Cohen RD
Year: 1996
Journal: Mamm Genome
Title: Localization of mouse peroxisome proliferator-activated receptor delta (Ppard) on chromosome 17 near colipase (Clps).
Volume: 7
Issue: 7
Pages: 557-8
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Publication
10319026 | J:51815
First Author: Ryffel B
Year: 1998
Journal: Int J Exp Pathol
Title: Failure to induce anti-glomerular basement membrane glomerulonephritis in TNF alpha/beta deficient mice.
Volume: 79
Issue: 6
Pages: 453-60
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Publication
21203444 | J:168336
First Author: Lai JF
Year: 2010
Journal: PLoS One
Title: Critical role of macrophages and their activation via MyD88-NFκB signaling in lung innate immunity to Mycoplasma pneumoniae.
Volume: 5
Issue: 12
Pages: e14417
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Publication
1672293 | J:11045
First Author: Nadeau JH
Year: 1991
Journal: Genomics
Title: Genetic maps of mouse chromosome 17 including 12 new anonymous DNA loci and 25 anchor loci.
Volume: 9
Issue: 1
Pages: 78-89
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Publication
8499655 | J:4581
First Author: Andalibi A
Year: 1993
Journal: Mamm Genome
Title: Mapping of multiple mouse loci related to the farnesyl pyrophosphate synthetase gene.
Volume: 4
Issue: 4
Pages: 211-9
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Publication
8661125 | J:33929
First Author: Doyle J
Year: 1996
Journal: Genomics
Title: Locations of human and mouse genes encoding the RFX1 and RFX2 transcription factor proteins.
Volume: 35
Issue: 1
Pages: 227-30
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Publication
18188184 | J:168191
First Author: Yadav N
Year: 2008
Journal: EMBO Rep
Title: CARM1 promotes adipocyte differentiation by coactivating PPARgamma.
Volume: 9
Issue: 2
Pages: 193-8
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Publication
16239576 | J:104292
First Author: van Rossum AM
Year: 2005
Journal: Infect Immun
Title: Host and bacterial factors contributing to the clearance of colonization by Streptococcus pneumoniae in a murine model.
Volume: 73
Issue: 11
Pages: 7718-26
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Publication
32179479 | J:306852
First Author: Zhu H
Year: 2020
Journal: iScience
Title: The Complement Regulator Susd4 Influences Nervous-System Function and Neuronal Morphology in Mice.
Volume: 23
Issue: 3
Pages: 100957
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Publication
8406442 | J:13241
First Author: Himmelbauer H
Year: 1993
Journal: Genomics
Title: High-resolution comparative mapping of mouse chromosome 17.
Volume: 17
Issue: 1
Pages: 110-20
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Publication
29279353 | J:273849
First Author: Sones JL
Year: 2018
Journal: FASEB J
Title: Angiogenic factor imbalance precedes complement deposition in placentae of the BPH/5 model of preeclampsia.
Volume: 32
Issue: 5
Pages: 2574-2586
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Publication
8798769 | J:35796
First Author: Nicoll DA
Year: 1996
Journal: J Biol Chem
Title: Cloning of a third mammalian Na+-Ca2+ exchanger, NCX3.
Volume: 271
Issue: 40
Pages: 24914-21
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Publication
30647151 | J:273194
First Author: Anderson SR
Year: 2019
Journal: J Neurosci
Title: Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia.
Volume: 39
Issue: 11
Pages: 2025-2040
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Publication
22100262 | J:178944
First Author: Daikoku T
Year: 2011
Journal: Dev Cell
Title: Conditional deletion of Msx homeobox genes in the uterus inhibits blastocyst implantation by altering uterine receptivity.
Volume: 21
Issue: 6
Pages: 1014-25
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Publication
23345428 | J:194335
First Author: Yang ZF
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: GABP transcription factor is required for development of chronic myelogenous leukemia via its control of PRKD2.
Volume: 110
Issue: 6
Pages: 2312-7
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Publication
6816725 | J:6915
First Author: Klein J
Year: 1982
Journal: Immunogenetics
Title: H-2 haplotypes, genes, and antigens: second listing. I. Non-H-2 loci on chromosome 17.
Volume: 16
Issue: 4
Pages: 285-317
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Publication
2574145 | J:10135
First Author: Vincek V
Year: 1989
Journal: Genomics
Title: Linkage map of mouse chromosome 17: localization of 27 new DNA markers.
Volume: 5
Issue: 4
Pages: 773-86
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Publication
1360278 | J:3226
First Author: Johnson KR
Year: 1992
Journal: Mamm Genome
Title: Genetic mapping of the murine gene and 14 related sequences encoding chromosomal protein HMG-14.
Volume: 3
Issue: 11
Pages: 625-32
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Publication
39503541 | J:361195
 
First Author: Moldovan GE
Year: 2025
Journal: Reproduction
Title: YAP1 and WWTR1 are required for murine pregnancy initiation.
Volume: 169
Issue: 1
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Publication
7558020 | J:25567
First Author: Kozak CA
Year: 1995
Journal: Genomics
Title: Genomic cloning of mouse MIF (macrophage inhibitory factor) and genetic mapping of the human and mouse expressed gene and nine mouse pseudogenes.
Volume: 27
Issue: 3
Pages: 405-11
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Publication
38164795 | J:344217
First Author: Roy TA
Year: 2024
Journal: Genes Brain Behav
Title: Discovery and validation of genes driving drug-intake and related behavioral traits in mice.
Volume: 23
Issue: 1
Pages: e12875
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Publication
38395995 | J:345820
First Author: Cardarelli S
Year: 2024
Journal: Cell Death Dis
Title: Modulation of cAMP/cGMP signaling as prevention of congenital heart defects in Pde2A deficient embryos: a matter of oxidative stress.
Volume: 15
Issue: 2
Pages: 169
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
37353485 | J:337474
First Author: Cobo I
Year: 2023
Journal: Nat Commun
Title: NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation.
Volume: 14
Issue: 1
Pages: 3761
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Publication
10501973 | J:62456
First Author: Lyu MS
Year: 1999
Journal: Mamm Genome
Title: Genetic mapping of six mouse peroxiredoxin genes and fourteen peroxiredoxin related sequences.
Volume: 10
Issue: 10
Pages: 1017-9
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
33153107 | J:298990
 
First Author: Sah RK
Year: 2020
Journal: Int J Mol Sci
Title: Targeted Disruption of Mouse Dip2B Leads to Abnormal Lung Development and Prenatal Lethality.
Volume: 21
Issue: 21
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
24006456 | J:221550
First Author: Abonnenc M
Year: 2013
Journal: Circ Res
Title: Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Volume: 113
Issue: 10
Pages: 1138-47
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
8288233 | J:15567
First Author: Warden CH
Year: 1993
Journal: Genomics
Title: Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse.
Volume: 18
Issue: 2
Pages: 295-307
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
23012479 | J:190322
First Author: Archambaud C
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Impact of lactobacilli on orally acquired listeriosis.
Volume: 109
Issue: 41
Pages: 16684-9
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Publication
8827514 | J:34178
First Author: Welch CL
Year: 1996
Journal: J Lipid Res
Title: Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes.
Volume: 37
Issue: 7
Pages: 1406-21
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
28700664 | J:246066
First Author: Sundberg JP
Year: 2017
Journal: PLoS One
Title: Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
Volume: 12
Issue: 7
Pages: e0180682
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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