|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 801 to 900 out of 1952 for Cdkn2a

<< First    < Previous  |  Next >    Last >>
0.033s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7610019
Age: postnatal
Image: S6Aa Arf
Specimen Label: S6Aa Arf
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7610019
Age: postnatal
Image: S6Ac
Specimen Label: S6Ac
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4882157
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944631
Age: postnatal day 7
Image: g00042 P7
Specimen Label: g00042 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4882305
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944635
Age: postnatal day 7
Image: g00046 P7
Specimen Label: g00046 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4882157
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944631
Age: embryonic day 11.5
Image: g00042 E11.5
Specimen Label: g00042 E11.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4882305
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944635
Age: embryonic day 11.5
Image: g00046 E11.5
Specimen Label: g00046 E11.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5313325
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609217
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6886042
Age: embryonic day 10.5
Image: 3A E10.5
Note: Expression in abundant cells in motoneuron zone; expression in a subpopulation of motoneurons.
Specimen Label: 3A E10.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4882157
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944631
Age: postnatal day 7
Image: g00042 P7
Specimen Label: g00042 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4882305
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944635
Age: postnatal day 7
Image: g00046 P7
Specimen Label: g00046 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5313325
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3263020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6886042
Age: embryonic day 12.5
Image: 3B
Note: Expression restricted to apical ectodermal ridge.
Specimen Label: 3B
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_04
Specimen Label: euxassay_002902_04
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_05
Specimen Label: euxassay_002902_05
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_06
Specimen Label: euxassay_002902_06
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_07
Specimen Label: euxassay_002902_07
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_08
Specimen Label: euxassay_002902_08
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_09
Specimen Label: euxassay_002902_09
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_10
Specimen Label: euxassay_002902_10
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_19
Specimen Label: euxassay_002902_19
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_20
Specimen Label: euxassay_002902_20
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_21
Specimen Label: euxassay_002902_21
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_22
Specimen Label: euxassay_002902_22
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_23
Specimen Label: euxassay_002902_23
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_24
Specimen Label: euxassay_002902_24
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7610019
Age: embryonic day 13.5
Image: 5Aa
Specimen Label: 5Aa
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7610019
Age: embryonic day 13.5
Image: 5Ac
Specimen Label: 5Ac
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7610019
Age: embryonic day 13.5
Image: 5Ad
Specimen Label: 5Ad
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4882157
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944631
Age: postnatal day 7
Image: g00042 P7
Specimen Label: g00042 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4882305
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944635
Age: postnatal day 7
Image: g00046 P7
Specimen Label: g00046 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_05
Specimen Label: euxassay_002902_05
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_22
Specimen Label: euxassay_002902_22
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_23
Specimen Label: euxassay_002902_23
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4882157
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944631
Age: embryonic day 15.5
Image: g00042 E15.5
Specimen Label: g00042 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4882157
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944631
Age: postnatal day 7
Image: g00042 P7
Specimen Label: g00042 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4882305
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944635
Age: embryonic day 15.5
Image: g00046 E15.5
Specimen Label: g00046 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4882305
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944635
Age: postnatal day 7
Image: g00046 P7
Specimen Label: g00046 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4882157
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944631
Age: embryonic day 15.5
Image: g00042 E15.5
Specimen Label: g00042 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4882305
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944635
Age: embryonic day 15.5
Image: g00046 E15.5
Specimen Label: g00046 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_08
Specimen Label: euxassay_002902_08
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_09
Specimen Label: euxassay_002902_09
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_20
Specimen Label: euxassay_002902_20
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1044888
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823787
Age: embryonic day 14.5
Image: euxassay_002902_21
Specimen Label: euxassay_002902_21
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4882157
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944631
Age: embryonic day 15.5
Image: g00042 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00042 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4882157
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944631
Age: postnatal day 7
Image: g00042 P7
Specimen Label: g00042 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4882305
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944635
Age: embryonic day 15.5
Image: g00046 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00046 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4882305
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944635
Age: postnatal day 7
Image: g00046 P7
Note: Expression was region specific and scattered.
Specimen Label: g00046 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5313325
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-04
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1757720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6886042
Age: embryonic day 12.5
Image: 3A E12.5
Note: Number of expressing cells decreases from E10.5 to E12.5.
Specimen Label: 3A E12.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7608420
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7610020
Age: embryonic day 13.5
Image: 4Aa
Specimen Label: 4Aa
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7608420
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7610020
Age: embryonic day 13.5
Image: 4Ab
Specimen Label: 4Ab
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7608420
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-05
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1783721
Pattern: Single cells
Stage: TS21
Assay Id: MGI:7610020
Age: embryonic day 13.5
Image: 4Ac
Specimen Label: 4Ac
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3803228
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7610021
Age: embryonic day 15.5
Image: 4Bb
Note: Nearly all the hyperplastic vitreous cells were immunolabeled for the GFP reporter.
Specimen Label: 4Bb
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3803228
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1783723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7610021
Age: embryonic day 15.5
Image: 4Bd
Note: GFP staining was markedly decreased in the Tgfb2<-/->;Arf hyperplastic vitreous cells.
Specimen Label: 4Bd
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7610019
Age: embryonic day 13.5
Image: 4Ca
Specimen Label: 4Ca
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1783721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7610019
Age: embryonic day 13.5
Image: 4Cb
Note: Staining was markedly decreased in the Tgfb2<-/->;Arf hyperplastic vitreous cells.
Specimen Label: 4Cb
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3803228
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7610021
Age: embryonic day 13.5
Image: 4Da
Note: Staining in an adjacent section indicated that some Cdkn2a-expressing cells also express Tgfbr2.
Specimen Label: 4Da
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7284216
Assay Type: Immunohistochemistry
Annotation Date: 2022-06-08
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7284268
Age: embryonic day 11.5
Image: 5E p27-/- Nczf+/+ p16
Note: Expression pattern in wild type not reported.
Specimen Label: 5E p27-/- Nczf+/+ p16
Specimen Num: 1
•
•
•
•
•
Publication
10753221 | J:61786
First Author: Meléndez B
Year: 2000
Journal: Carcinogenesis
Title: Characterization of the murine p19(ARF) promoter CpG island and its methylation pattern in primary lymphomas.
Volume: 21
Issue: 4
Pages: 817-21
•
•
•
•
•
Publication
15567177 | J:94162
First Author: Suzuki H
Year: 2005
Journal: Biochem Biophys Res Commun
Title: The ARF tumor suppressor inhibits BCL6-mediated transcriptional repression.
Volume: 326
Issue: 1
Pages: 242-8
•
•
•
•
•
Publication
17486078 | J:189986
First Author: Reef S
Year: 2007
Journal: Oncogene
Title: The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein.
Volume: 26
Issue: 46
Pages: 6677-83
•
•
•
•
•
Publication
9178896 | J:39206
First Author: Malumbres M
Year: 1997
Journal: Oncogene
Title: Inactivation of the cyclin-dependent kinase inhibitor p15INK4b by deletion and de novo methylation with independence of p16INK4a alterations in murine primary T-cell lymphomas.
Volume: 14
Issue: 11
Pages: 1361-70
•
•
•
•
•
Publication
17043139 | J:114509
First Author: Wasmeier C
Year: 2006
Journal: J Cell Biol
Title: Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes.
Volume: 175
Issue: 2
Pages: 271-81
•
•
•
•
•
Publication
31428695 | J:288816
 
First Author: Cottage CT
Year: 2019
Journal: Commun Biol
Title: Targeting p16-induced senescence prevents cigarette smoke-induced emphysema by promoting IGF1/Akt1 signaling in mice.
Volume: 2
Pages: 307
•
•
•
•
•
Publication
36125896 | J:337607
 
First Author: Haase S
Year: 2022
Journal: J Clin Invest
Title: H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models.
Volume: 132
Issue: 22
•
•
•
•
•
Publication
19390085 | J:147943
First Author: Dhawan S
Year: 2009
Journal: Genes Dev
Title: Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation.
Volume: 23
Issue: 8
Pages: 906-11
•
•
•
•
•
Publication
22351929 | J:182507
First Author: Oguro H
Year: 2012
Journal: J Exp Med
Title: Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes.
Volume: 209
Issue: 3
Pages: 445-54
•
•
•
•
•
Publication
23029524 | J:191959
First Author: Fan L
Year: 2012
Journal: PLoS One
Title: Bmi1 is required for hepatic progenitor cell expansion and liver tumor development.
Volume: 7
Issue: 9
Pages: e46472
•
•
•
•
•
Publication
30895687 | J:291357
First Author: Chen G
Year: 2019
Journal: Stem Cells
Title: Bmi1 Overexpression in Mesenchymal Stem Cells Exerts Antiaging and Antiosteoporosis Effects by Inactivating p16/p19 Signaling and Inhibiting Oxidative Stress.
Volume: 37
Issue: 9
Pages: 1200-1211
•
•
•
•
•
Publication
25832744 | J:224107
First Author: Yamakoshi K
Year: 2015
Journal: Aging Cell
Title: Dysregulation of the Bmi-1/p16(Ink⁴a) pathway provokes an aging-associated decline of submandibular gland function.
Volume: 14
Issue: 4
Pages: 616-24
•
•
•
•
•
Publication
20207230 | J:158982
First Author: Oguro H
Year: 2010
Journal: Cell Stem Cell
Title: Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1.
Volume: 6
Issue: 3
Pages: 279-86
•
•
•
•
•
Publication
16954369 | J:124627
First Author: Oguro H
Year: 2006
Journal: J Exp Med
Title: Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice.
Volume: 203
Issue: 10
Pages: 2247-53
•
•
•
•
•
Publication
9923679 | J:52056
First Author: Jacobs JJ
Year: 1999
Journal: Nature
Title: The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus.
Volume: 397
Issue: 6715
Pages: 164-8
•
•
•
•
•
Publication
14574365 | J:89979
First Author: Molofsky AV
Year: 2003
Journal: Nature
Title: Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation.
Volume: 425
Issue: 6961
Pages: 962-7
•
•
•
•
•
Publication
28790310 | J:275156
First Author: Jin J
Year: 2017
Journal: Sci Rep
Title: P16 INK4a Deletion Ameliorated Renal Tubulointerstitial Injury in a Stress-induced Premature Senescence Model of Bmi-1 Deficiency.
Volume: 7
Issue: 1
Pages: 7502
•
•
•
•
•
Publication
24915841 | J:216517
First Author: Jin J
Year: 2014
Journal: Aging Cell
Title: Bmi-1 plays a critical role in protection from renal tubulointerstitial injury by maintaining redox balance.
Volume: 13
Issue: 5
Pages: 797-809
•
•
•
•
•
Publication
31959867 | J:333099
First Author: Chen H
Year: 2020
Journal: Exp Mol Med
Title: TGF-β1/IL-11/MEK/ERK signaling mediates senescence-associated pulmonary fibrosis in a stress-induced premature senescence model of Bmi-1 deficiency.
Volume: 52
Issue: 1
Pages: 130-151
•
•
•
•
•
Publication
18635350 | J:139803
First Author: Pietersen AM
Year: 2008
Journal: Curr Biol
Title: Bmi1 regulates stem cells and proliferation and differentiation of committed cells in mammary epithelium.
Volume: 18
Issue: 14
Pages: 1094-9
•
•
•
•
•
Publication
11779495 | J:88792
First Author: Sharpless NE
Year: 2001
Journal: Mol Cell
Title: Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions.
Volume: 8
Issue: 6
Pages: 1187-96
•
•
•
•
•
Publication
16510579 | J:106704
First Author: van Schanke A
Year: 2006
Journal: Cancer Res
Title: Induction of nevi and skin tumors in Ink4a/Arf Xpa knockout mice by neonatal, intermittent, or chronic UVB exposures.
Volume: 66
Issue: 5
Pages: 2608-15
•
•
•
•
•
Publication
31563962 | J:309367
First Author: Fu Y
Year: 2020
Journal: Neuro Oncol
Title: TSPO deficiency induces mitochondrial dysfunction, leading to hypoxia, angiogenesis, and a growth-promoting metabolic shift toward glycolysis in glioblastoma.
Volume: 22
Issue: 2
Pages: 240-252
•
•
•
•
•
Publication
17912041 | J:222385
First Author: Lee HJ
Year: 2007
Journal: Cell Cycle
Title: Loss of CABLES1, a cyclin-dependent kinase-interacting protein that inhibits cell cycle progression, results in germline expansion at the expense of oocyte quality in adult female mice.
Volume: 6
Issue: 21
Pages: 2678-84
•
•
•
•
•
Publication
37106126 | J:337454
First Author: Guijarro MV
Year: 2023
Journal: Oncogene
Title: TYMS promotes genomic instability and tumor progression in Ink4a/Arf null background.
Volume: 42
Issue: 23
Pages: 1926-1939
•
•
•
•
•
Publication
24338698 | J:209290
First Author: Catucci M
Year: 2014
Journal: Eur J Immunol
Title: Wiskott-Aldrich syndrome protein deficiency in natural killer and dendritic cells affects antitumor immunity.
Volume: 44
Issue: 4
Pages: 1039-45
•
•
•
•
•
Publication
9353252 | J:44088
First Author: Chin L
Year: 1997
Journal: Genes Dev
Title: Cooperative effects of INK4a and ras in melanoma susceptibility in vivo.
Volume: 11
Issue: 21
Pages: 2822-34
•
•
•
•
•
Publication
24056773 | J:202318
First Author: Pyonteck SM
Year: 2013
Journal: Nat Med
Title: CSF-1R inhibition alters macrophage polarization and blocks glioma progression.
Volume: 19
Issue: 10
Pages: 1264-72
•
•
•
•
•
Publication
25543281 | J:232692
First Author: Rotty JD
Year: 2015
Journal: Dev Cell
Title: Profilin-1 serves as a gatekeeper for actin assembly by Arp2/3-dependent and -independent pathways.
Volume: 32
Issue: 1
Pages: 54-67
•
•
•
•
•
Publication
24147027 | J:225181
First Author: Pong WW
Year: 2013
Journal: PLoS One
Title: F11R is a novel monocyte prognostic biomarker for malignant glioma.
Volume: 8
Issue: 10
Pages: e77571
•
•
•
•
•
Publication
30456364 | J:286031
First Author: Giessner C
Year: 2018
Journal: Life Sci Alliance
Title: Vnn1 pantetheinase limits the Warburg effect and sarcoma growth by rescuing mitochondrial activity.
Volume: 1
Issue: 4
Pages: e201800073
•
•
•
•
•
Publication
28759044 | J:247694
First Author: Yan D
Year: 2017
Journal: Oncogene
Title: Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas.
Volume: 36
Issue: 43
Pages: 6049-6058
•
•
•
•
•
Publication
38566120 | J:346860
First Author: Yalcin F
Year: 2024
Journal: Acta Neuropathol Commun
Title: Tumor associated microglia/macrophages utilize GPNMB to promote tumor growth and alter immune cell infiltration in glioma.
Volume: 12
Issue: 1
Pages: 50
•
•
•
•
•
Publication
16620915 | J:110215
First Author: Cheong C
Year: 2006
Journal: Mech Ageing Dev
Title: Role of INK4a locus in normal eye development and cataract genesis.
Volume: 127
Issue: 7
Pages: 633-8
•
•
•
•
•
Publication
19805150 | J:153678
First Author: Tamase A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin.
Volume: 106
Issue: 40
Pages: 17163-8
•
•
•
•
•
Publication
26884185 | J:231005
First Author: Lissanu Deribe Y
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma.
Volume: 113
Issue: 9
Pages: E1296-305
•
•
•
•
•
Publication
17099725 | J:122886
First Author: Nilsson LM
Year: 2007
Journal: Oncogene
Title: Ink4c is dispensable for tumor suppression in Myc-induced B-cell lymphomagenesis.
Volume: 26
Issue: 20
Pages: 2833-9
•
•
•
•
•
Publication
17510401 | J:121732
First Author: Ramsey MR
Year: 2007
Journal: Cancer Res
Title: Expression of p16Ink4a compensates for p18Ink4c loss in cyclin-dependent kinase 4/6-dependent tumors and tissues.
Volume: 67
Issue: 10
Pages: 4732-41
•
•
•
•
•
Publication
21245485 | J:170512
First Author: Liu Y
Year: 2011
Journal: Blood
Title: Expression of p16(INK4a) prevents cancer and promotes aging in lymphocytes.
Volume: 117
Issue: 12
Pages: 3257-67
•
•
•
•
•
Publication
10435599 | J:56600
First Author: Meléndez B
Year: 1999
Journal: Oncogene
Title: Loss of heterozygosity at the proximal-mid part of mouse chromosome 4 defines two novel tumor suppressor gene loci in T-cell lymphomas.
Volume: 18
Issue: 28
Pages: 4166-9
•
•
•
•
•
Publication
22065720 | J:181044
First Author: Grange M
Year: 2012
Journal: Cancer Res
Title: Activated STAT5 promotes long-lived cytotoxic CD8+ T cells that induce regression of autochthonous melanoma.
Volume: 72
Issue: 1
Pages: 76-87
•
•
•
•
•
Publication
37353538 | J:338133
First Author: Matsudaira T
Year: 2023
Journal: Commun Biol
Title: Cellular senescence in white matter microglia is induced during ageing in mice and exacerbates the neuroinflammatory phenotype.
Volume: 6
Issue: 1
Pages: 665
•
•
•
•
•
Publication
24091330 | J:203979
First Author: Wang Y
Year: 2013
Journal: J Clin Invest
Title: p16(INK4a) protects against dysfunctional telomere-induced ATR-dependent DNA damage responses.
Volume: 123
Issue: 10
Pages: 4489-501
•
•
•
•
•
Publication
25882552 | J:247262
First Author: Grange M
Year: 2015
Journal: Immunology
Title: Control of CD8 T cell proliferation and terminal differentiation by active STAT5 and CDKN2A/CDKN2B.
Volume: 145
Issue: 4
Pages: 543-57
•
•
•
•
•
Publication
26139534 | J:225832
First Author: Giordano M
Year: 2015
Journal: EMBO J
Title: Molecular profiling of CD8 T cells in autochthonous melanoma identifies Maf as driver of exhaustion.
Volume: 34
Issue: 15
Pages: 2042-58
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom