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Search results 801 to 841 out of 841 for Cebpb

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0.02s

Type

Details

Score

Genotype

Symbol:	Dbt/Dbt Tg(tetO-DBT)525AGeh/? Tg(Cebpb-tTA)5Bjd/?
Background:	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB * NMRI
Zygosity:	cx
Has Mutant Allele:	true

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Genotype

Symbol:	Kdr/Kdr<+> Tg(tetO-Kdr*)4377.5Rwng/? Tg(Cebpb-tTA)5Bjd/?
Background:	involves: 129S1/Sv * 129X1/SvJ * FVB/N * NMRI
Zygosity:	cx
Has Mutant Allele:	true

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Protein

E9Q1F7

Organism:	Mus musculus/domesticus
Length:	211
Fragment?:	true

•

Protein

F6ZCH1

Organism:	Mus musculus/domesticus
Length:	66
Fragment?:	true

•

Protein

F6SIC5

Organism:	Mus musculus/domesticus
Length:	118
Fragment?:	true

•

Publication

9224714 | -

First Author:	Grant PA
Year:	1997
Journal:	Genes Dev
Title:	Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex.
Volume:	11
Issue:	13
Pages:	1640-50

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Protein Domain

IPR037800 | GCN5

Type:

Family

Description:

This entry includes histone acetyltransferases GCN5, KAT2A and KAT2B (all of which are included in ). GCN5 acetylates histones H2B, H3 and H4, providing a specific tag for epigenetic transcription activation. GCN5 is a component of the transcription regulatory histone acetylation (HAT) complexes SAGA [], SLIK [], SALSA []and ADA []. Mammals have two paralogues: KAT2A (also known as GCN5) and KAT2B. KAT2A acetylates core histones to provide a specific tag for epigenetic transcription activation, but not nucleosome core particles. It also acetylates proteins such as CEBPB []. KAT2A is a component of the ATAC complex, which has acetyltransferase activity on histones H3 and H4 []. KAT2B (also known as P300/calcium-binding protein (CBP)-associated factor or PCAF) can acetylate the core histones H3 and H4 as well as nucleosome core particles and non-histone proteins such as ACLY [].The transcription regulatory histone acetylation complex Spt-Ada-Gcn5 acetyltransferase (SAGA) is involved in RNA polymerase II-dependent transcriptional regulation of approximately 10% of yeast genes. SAGA preferentially acetylates histones H3 and H2B and deubiquitinates histone H2B []. SAGA is known as PCAF in vertebrates and PCAF acetylates nucleosomal histone H3 []. The SAGA complex consists of at least TRA1, CHD1, SPT7, TAF5, ADA3, SGF73, SPT20/ADA5, SPT8, TAF12, TAF6, HFI1/ADA1, UBP8, GCN5, ADA2, SPT3, SGF29, TAF10, TAF9, SGF11 and SUS1, and some of these components are present as two copies. The complex is built up from distinct modules, each of which has a separate function and crosslinks with either other proteins or other modules in the complex [].SLIK (SAGA-like) is a multi-subunit histone acetyltransferase complex that preferentially acetylates histones H3 and H2B and deubiquitinates histone H2B. It is an embellishment of the SAGA complex. The yeast SLIK complex consists of at least TRA1, CHD1, SPT7, CC TAF5, ADA3, SPT20, RTG2, TAF12, TAF6, HFI1, UBP8 (a deubiquitinase), GCN5, ADA2, SPT3, SGF29, TAF10 and TAF9 [, ].The yeast SALSA complex is an altered form of the SAGA complex and consists of at least TRA1, SPT7 (C-terminal truncated form), TAF5, ADA3, SPT20, TAF12, TAF6, HFI1, GCN5, ADA2 and SPT3 [].The ADA complex is a transcription regulatory histone acetylation (HAT) complex. ADA preferentially acetylates nucleosomal histones H3 (at 'Lys-14' and 'Lys-18') and H2B. The complex consists of at least ADA2, ADA3, AHC1, and GCN5. AHC1 is required for the overall structural integrity of the ADA complex [].

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Publication

22190699 | J:185769

First Author:	Le JA
Year:	2012
Journal:	Biol Reprod
Title:	Generation of mice expressing only the long form of the prolactin receptor reveals that both isoforms of the receptor are required for normal ovarian function.
Volume:	86
Issue:	3
Pages:	86

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Publication

26655697 | J:235897

First Author:	Li Z
Year:	2015
Journal:	Cell Metab
Title:	Hypothalamic Amylin Acts in Concert with Leptin to Regulate Food Intake.
Volume:	22
Issue:	6
Pages:	1059-67

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Publication

36055226 | J:328531

First Author:	Ma C
Year:	2022
Journal:	Cancer Cell
Title:	Platelets control liver tumor growth through P2Y12-dependent CD40L release in NAFLD.
Volume:	40
Issue:	9
Pages:	986-998.e5

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Publication

22556267 | J:184782

First Author:	O'Donnell KA
Year:	2012
Journal:	Proc Natl Acad Sci U S A
Title:	A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer.
Volume:	109
Issue:	21
Pages:	E1377-86

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Publication

20640885 | J:172622

First Author:	Schönig K
Year:	2011
Journal:	Transgenic Res
Title:	Development of a BAC vector for integration-independent and tight regulation of transgenes in rodents via the Tet system.
Volume:	20
Issue:	3
Pages:	709-20

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Publication

19105207 | J:186226

First Author:	Ney JT
Year:	2009
Journal:	Hepatology
Title:	Autochthonous liver tumors induce systemic T cell tolerance associated with T cell receptor down-modulation.
Volume:	49
Issue:	2
Pages:	471-81

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Publication

23932781 | -

First Author:	Lin R
Year:	2013
Journal:	Mol Cell
Title:	Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth.
Volume:	51
Issue:	4
Pages:	506-518

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Publication

10026213 | -

First Author:	Grant PA
Year:	1999
Journal:	J Biol Chem
Title:	Expanded lysine acetylation specificity of Gcn5 in native complexes.
Volume:	274
Issue:	9
Pages:	5895-900

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Publication

9885573 | -

First Author:	Grant PA
Year:	1998
Journal:	Mol Cell
Title:	The ATM-related cofactor Tra1 is a component of the purified SAGA complex.
Volume:	2
Issue:	6
Pages:	863-7

•

Publication

18160458 | J:133454

First Author:	Paglialunga S
Year:	2008
Journal:	Am J Physiol Endocrinol Metab
Title:	Acylation-stimulating protein deficiency and altered adipose tissue in alternative complement pathway knockout mice.
Volume:	294
Issue:	3
Pages:	E521-9

•

Publication

15944181 | J:100427

First Author:	Carpenter B
Year:	2005
Journal:	Development
Title:	VEGF is crucial for the hepatic vascular development required for lipoprotein uptake.
Volume:	132
Issue:	14
Pages:	3293-303

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Publication

29136504 | J:249174

First Author:	Sun X
Year:	2017
Journal:	Cancer Cell
Title:	Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver Cancer.
Volume:	32
Issue:	5
Pages:	574-589.e6

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Publication

38657045 | J:354109

First Author:	Bakiri L
Year:	2024
Journal:	Proc Natl Acad Sci U S A
Title:	Liver cancer development driven by the AP-1/c-Jun~Fra-2 dimer through c-Myc.
Volume:	121
Issue:	18
Pages:	e2404188121

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Publication

32694609 | J:294996

First Author:	Méndez-Lucas A
Year:	2020
Journal:	Nat Metab
Title:	Identifying strategies to target the metabolic flexibility of tumours.
Volume:	2
Issue:	4
Pages:	335-350

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Publication

16579849 | J:119973

First Author:	Homanics GE
Year:	2006
Journal:	BMC Med Genet
Title:	Production and characterization of murine models of classic and intermediate maple syrup urine disease.
Volume:	7

Pages:	33

•

Publication

19103755 | J:145720

First Author:	Guelman S
Year:	2009
Journal:	Mol Cell Biol
Title:	The double-histone-acetyltransferase complex ATAC is essential for mammalian development.
Volume:	29
Issue:	5
Pages:	1176-88

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Protein

Q99KW4

Organism:	Mus musculus/domesticus
Length:	116
Fragment?:	true

•

Protein

Q3UVE8

Organism:	Mus musculus/domesticus
Length:	660
Fragment?:	true

•

Publication

31924786 | J:283951

First Author:	Wang G
Year:	2020
Journal:	Nat Commun
Title:	Arf1-mediated lipid metabolism sustains cancer cells and its ablation induces anti-tumor immune responses in mice.
Volume:	11
Issue:	1
Pages:	220

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Publication

23703832 | J:213764

First Author:	Hasenfuss SC
Year:	2014
Journal:	Hepatology
Title:	Activator Protein 1 transcription factor Fos-related antigen 1 (Fra-1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism.
Volume:	59
Issue:	1
Pages:	261-73

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Protein

Q3U2D4

Organism:	Mus musculus/domesticus
Length:	473
Fragment?:	false

•

Publication

12817992 | J:84503

First Author:	Tilli MT
Year:	2003
Journal:	Breast Cancer Res
Title:	Conditional mouse models demonstrate oncogene-dependent differences in tumor maintenance and recurrence.
Volume:	5
Issue:	4
Pages:	202-5

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Protein

Q9JHD1

Organism:	Mus musculus/domesticus
Length:	813
Fragment?:	false

•

Protein

Q9JHD2

Organism:	Mus musculus/domesticus
Length:	830
Fragment?:	false

•

Protein

Q6P3Z8

Organism:	Mus musculus/domesticus
Length:	829
Fragment?:	false

•

Protein

Q3UD69

Organism:	Mus musculus/domesticus
Length:	830
Fragment?:	false

•

Protein

Q3UM02

Organism:	Mus musculus/domesticus
Length:	833
Fragment?:	false

•

Protein

B2RR30

Organism:	Mus musculus/domesticus
Length:	813
Fragment?:	false

•

Publication

12186975 | -

First Author:	Sterner DE
Year:	2002
Journal:	Proc Natl Acad Sci U S A
Title:	SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription.
Volume:	99
Issue:	18
Pages:	11622-7

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Publication

24411941 | J:210545

First Author:	Hasenfuss SC
Year:	2014
Journal:	Cell Metab
Title:	Regulation of steatohepatitis and PPARγ signaling by distinct AP-1 dimers.
Volume:	19
Issue:	1
Pages:	84-95

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Publication

15647753 | -

First Author:	Pray-Grant MG
Year:	2005
Journal:	Nature
Title:	Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation.
Volume:	433
Issue:	7024
Pages:	434-8

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Publication

12446794 | -

First Author:	Pray-Grant MG
Year:	2002
Journal:	Mol Cell Biol
Title:	The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.
Volume:	22
Issue:	24
Pages:	8774-86

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Publication

25216679 | -

First Author:	Han Y
Year:	2014
Journal:	EMBO J
Title:	Architecture of the Saccharomyces cerevisiae SAGA transcription coactivator complex.
Volume:	33
Issue:	21
Pages:	2534-46

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Publication

9674425 | J:320277

First Author:	Ogryzko VV
Year:	1998
Journal:	Cell
Title:	Histone-like TAFs within the PCAF histone acetylase complex.
Volume:	94
Issue:	1
Pages:	35-44

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Search results 801 to 841 out of 841 for Cebpb

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