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Search results 801 to 900 out of 1157 for Cftr

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:4428161
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5422519
Age: embryonic day 14.5
Specimen Label: EB1420; Specimen B452
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4428161
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5422519
Age: embryonic day 14.5
Specimen Label: EB1420; Specimen B452
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4428161
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5422519
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: EB1420; Specimen B452
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4428161
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5422519
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: EB1420; Specimen B452
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6169694
Assay Type: RNA in situ
Annotation Date: 2020-04-28
Strength: Present
Sex: Male
Emaps: EMAPS:3798428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6406540
Age: postnatal day 4
Image: 4G
Note: Expressed in the soft tissues surrounding spinal cord.
Specimen Label: 4G
Detected: true
Specimen Num: 1
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Publication
- | J:43902
   
First Author: Welsh MJ
Year: 1995
Title: Chapter 127. Cystic Fibrosis
Volume: III
Pages: 3799-3876
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Publication
25085879 | J:252037
First Author: Pewzner-Jung Y
Year: 2014
Journal: EMBO Mol Med
Title: Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa.
Volume: 6
Issue: 9
Pages: 1205-14
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Publication
19562038 | J:150184
First Author: Trudel S
Year: 2009
Journal: PLoS One
Title: Peroxiredoxin 6 fails to limit phospholipid peroxidation in lung from Cftr-knockout mice subjected to oxidative challenge.
Volume: 4
Issue: 6
Pages: e6075
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Publication
30892081 | J:276838
First Author: Rymut SM
Year: 2019
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Acetyl-CoA carboxylase inhibition regulates microtubule dynamics and intracellular transport in cystic fibrosis epithelial cells.
Volume: 316
Issue: 6
Pages: L1081-L1093
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Publication
10878096 | J:134183
 
First Author: Kibble JD
Year: 2000
Journal: J Physiol
Title: Evidence for cystic fibrosis transmembrane conductance regulator-dependent sodium reabsorption in kidney, using Cftr(tm2cam) mice.
Volume: 526 Pt 1
Pages: 27-34
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Publication
30004386 | J:267908
   
First Author: Ahmadi S
Year: 2018
Journal: Elife
Title: SLC6A14, an amino acid transporter, modifies the primary CF defect in fluid secretion.
Volume: 7
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Publication
18955860 | J:323251
First Author: Ohlsson L
Year: 2008
Journal: J Pediatr Gastroenterol Nutr
Title: Expression of intestinal and lung alkaline sphingomyelinase and neutral ceramidase in cystic fibrosis f508del transgenic mice.
Volume: 47
Issue: 5
Pages: 547-54
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Publication
16537650 | J:106991
First Author: Yang L
Year: 2006
Journal: J Cell Sci
Title: Apical localization of ITPK1 enhances its ability to be a modifier gene product in a murine tracheal cell model of cystic fibrosis.
Volume: 119
Issue: Pt 7
Pages: 1320-8
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Publication
16184195 | J:101529
First Author: Clayburgh DR
Year: 2005
Journal: J Clin Invest
Title: Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo.
Volume: 115
Issue: 10
Pages: 2702-15
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Publication
10570187 | J:58571
First Author: Freedman SD
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: A membrane lipid imbalance plays a role in the phenotypic expression of cystic fibrosis in cftr(-/-) mice.
Volume: 96
Issue: 24
Pages: 13995-4000
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Publication
34261337 | J:320545
First Author: Ma J
Year: 2021
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Neutrophil elastase-regulated macrophage sheddome/secretome and phagocytic failure.
Volume: 321
Issue: 3
Pages: L555-L565
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Publication
21078296 | J:167052
First Author: Becker KA
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Accumulation of ceramide in the trachea and intestine of cystic fibrosis mice causes inflammation and cell death.
Volume: 403
Issue: 3-4
Pages: 368-74
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Publication
26883959 | J:270906
 
First Author: Cigana C
Year: 2016
Journal: Sci Rep
Title: Tracking the immunopathological response to Pseudomonas aeruginosa during respiratory infections.
Volume: 6
Pages: 21465
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Publication
36516754 | J:340909
First Author: Öz HH
Year: 2022
Journal: Cell Rep
Title: Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis.
Volume: 41
Issue: 11
Pages: 111797
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Publication
26604306 | J:228125
First Author: Riazanski V
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: TRPC6 channel translocation into phagosomal membrane augments phagosomal function.
Volume: 112
Issue: 47
Pages: E6486-95
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Publication
16093421 | J:101250
First Author: McDaniel N
Year: 2005
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Role of Na-K-2Cl cotransporter-1 in gastric secretion of nonacidic fluid and pepsinogen.
Volume: 289
Issue: 3
Pages: G550-60
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Publication
11557509 | J:72102
First Author: De Lisle RC
Year: 2001
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Changes in the exocrine pancreas secondary to altered small intestinal function in the CF mouse.
Volume: 281
Issue: 4
Pages: G899-906
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Publication
15696103 | J:105450
First Author: Saadane A
Year: 2005
Journal: J Allergy Clin Immunol
Title: Role of IL-10 deficiency in excessive nuclear factor-kappaB activation and lung inflammation in cystic fibrosis transmembrane conductance regulator knockout mice.
Volume: 115
Issue: 2
Pages: 405-11
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Publication
10930443 | J:111647
First Author: Kelley TJ
Year: 2000
Journal: J Clin Invest
Title: In vivo alterations of IFN regulatory factor-1 and PIAS1 protein levels in cystic fibrosis epithelium.
Volume: 106
Issue: 3
Pages: 403-10
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Publication
9843919 | J:52094
First Author: Cressman VL
Year: 1998
Journal: Am J Respir Cell Mol Biol
Title: The relationship of chronic mucin secretion to airway disease in normal and CFTR-deficient mice.
Volume: 19
Issue: 6
Pages: 853-66
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Publication
9739054 | J:115209
First Author: Kelley TJ
Year: 1998
Journal: J Clin Invest
Title: Inducible nitric oxide synthase expression is reduced in cystic fibrosis murine and human airway epithelial cells.
Volume: 102
Issue: 6
Pages: 1200-7
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Publication
33859001 | J:304989
 
First Author: Nyström EEL
Year: 2021
Journal: Science
Title: An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function.
Volume: 372
Issue: 6539
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Publication
28213469 | J:241530
First Author: Molina SA
Year: 2017
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Insulin signaling via the PI3-kinase/Akt pathway regulates airway glucose uptake and barrier function in a CFTR-dependent manner.
Volume: 312
Issue: 5
Pages: L688-L702
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Publication
12529261 | J:83392
First Author: Hinojosa-Kurtzberg AM
Year: 2003
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Novel MUC1 splice variants contribute to mucin overexpression in CFTR-deficient mice.
Volume: 284
Issue: 5
Pages: G853-62
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Publication
18376404 | J:133678
First Author: Teichgräber V
Year: 2008
Journal: Nat Med
Title: Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis.
Volume: 14
Issue: 4
Pages: 382-91
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Publication
20522639 | J:163347
First Author: Canale-Zambrano JC
Year: 2010
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Toll-like receptor-4 genotype influences the survival of cystic fibrosis mice.
Volume: 299
Issue: 2
Pages: G381-90
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Publication
11823525 | J:74476
First Author: Soltys J
Year: 2002
Journal: J Immunol
Title: Functional IL-10 deficiency in the lung of cystic fibrosis (cftr(-/-)) and IL-10 knockout mice causes increased expression and function of B7 costimulatory molecules on alveolar macrophages.
Volume: 168
Issue: 4
Pages: 1903-10
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Publication
33839155 | J:313966
 
First Author: Gardner AI
Year: 2021
Journal: J Biol Chem
Title: Interferon regulatory factor 8 regulates expression of acid ceramidase and infection susceptibility in cystic fibrosis.
Volume: 296
Pages: 100650
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Publication
23523785 | J:201221
First Author: Ziobro R
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Ceramide mediates lung fibrosis in cystic fibrosis.
Volume: 434
Issue: 4
Pages: 705-9
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Publication
23645634 | J:318182
First Author: Solymosi EA
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Chloride transport-driven alveolar fluid secretion is a major contributor to cardiogenic lung edema.
Volume: 110
Issue: 25
Pages: E2308-16
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Publication
33139382 | J:323266
 
First Author: Becker KA
Year: 2021
Journal: Infect Immun
Title: Acid Ceramidase Rescues Cystic Fibrosis Mice from Pulmonary Infections.
Volume: 89
Issue: 2
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Publication
34579569 | J:312951
First Author: Loeven NA
Year: 2021
Journal: mBio
Title: The Burkholderia cenocepacia Type VI Secretion System Effector TecA Is a Virulence Factor in Mouse Models of Lung Infection.
Volume: 12
Issue: 5
Pages: e0209821
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Publication
34207085 | J:337715
 
First Author: Pariano M
Year: 2021
Journal: Int J Mol Sci
Title: Anakinra Activates Superoxide Dismutase 2 to Mitigate Inflammasome Activity.
Volume: 22
Issue: 12
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Publication
27493027 | J:238564
First Author: Yefimova MG
Year: 2016
Journal: Hum Mol Genet
Title: Myelinosomes act as natural secretory organelles in Sertoli cells to prevent accumulation of aggregate-prone mutant Huntingtin and CFTR.
Volume: 25
Issue: 19
Pages: 4170-4185
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Publication
22523395 | J:186267
First Author: Manson ME
Year: 2012
Journal: J Lipid Res
Title: Regulatory role of β-arrestin-2 in cholesterol processing in cystic fibrosis epithelial cells.
Volume: 53
Issue: 7
Pages: 1268-76
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Publication
20969732 | J:333128
First Author: Walker NM
Year: 2011
Journal: Acta Physiol (Oxf)
Title: Functional activity of Pat-1 (Slc26a6) Cl(−)/HCO₃(−) exchange in the lower villus epithelium of murine duodenum.
Volume: 201
Issue: 1
Pages: 21-31
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Publication
22895259 | J:192779
First Author: Song Y
Year: 2012
Journal: Am J Physiol Cell Physiol
Title: Deletion of Slc26a6 alters the stoichiometry of apical Cl-/HCO-3 exchange in mouse pancreatic duct.
Volume: 303
Issue: 8
Pages: C815-24
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Publication
28090087 | J:244167
 
First Author: Moretti S
Year: 2017
Journal: Nat Commun
Title: A mast cell-ILC2-Th9 pathway promotes lung inflammation in cystic fibrosis.
Volume: 8
Pages: 14017
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Publication
22534621 | J:198613
First Author: Meissner A
Year: 2012
Journal: Circulation
Title: Tumor necrosis factor-α-mediated downregulation of the cystic fibrosis transmembrane conductance regulator drives pathological sphingosine-1-phosphate signaling in a mouse model of heart failure.
Volume: 125
Issue: 22
Pages: 2739-50
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Publication
27496898 | J:236617
First Author: Henry CO
Year: 2016
Journal: Am J Physiol Lung Cell Mol Physiol
Title: In vitro and in vivo evidence for an inflammatory role of the calcium channel TRPV4 in lung epithelium: Potential involvement in cystic fibrosis.
Volume: 311
Issue: 3
Pages: L664-75
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Publication
11352827 | J:92456
First Author: Khatri IA
Year: 2001
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Characteristics of rodent intestinal mucin Muc3 and alterations in a mouse model of human cystic fibrosis.
Volume: 280
Issue: 6
Pages: G1321-30
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Publication
17272824 | J:136609
First Author: Saadane A
Year: 2007
Journal: Am J Respir Cell Mol Biol
Title: Parthenolide inhibits IkappaB kinase, NF-kappaB activation, and inflammatory response in cystic fibrosis cells and mice.
Volume: 36
Issue: 6
Pages: 728-36
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Publication
29021150 | J:250547
First Author: Jiang H
Year: 2017
Journal: J Exp Med
Title: Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders.
Volume: 214
Issue: 11
Pages: 3219-3238
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Publication
23606537 | J:202542
First Author: Zhang PX
Year: 2013
Journal: J Immunol
Title: Reduced caveolin-1 promotes hyperinflammation due to abnormal heme oxygenase-1 localization in lipopolysaccharide-challenged macrophages with dysfunctional cystic fibrosis transmembrane conductance regulator.
Volume: 190
Issue: 10
Pages: 5196-206
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Publication
25201511 | J:232461
 
First Author: Guillemot L
Year: 2014
Journal: Biochimie
Title: Cytosolic phospholipase A2α enhances mouse mortality induced by Pseudomonas aeruginosa pulmonary infection via interleukin 6.
Volume: 107 Pt A
Pages: 95-104
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Publication
21068358 | J:168506
First Author: Alper SL
Year: 2011
Journal: Am J Physiol Cell Physiol
Title: Native and recombinant Slc26a3 (downregulated in adenoma, Dra) do not exhibit properties of 2Cl-/1HCO3- exchange.
Volume: 300
Issue: 2
Pages: C276-86
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Publication
25840995 | J:232267
First Author: Woods PS
Year: 2015
Journal: Am J Physiol Lung Cell Mol Physiol
Title: TGF-β-induced IL-6 prevents development of acute lung injury in influenza A virus-infected F508del CFTR-heterozygous mice.
Volume: 308
Issue: 11
Pages: L1136-44
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Publication
27834195 | J:239410
First Author: Li M
Year: 2017
Journal: Am J Physiol Cell Physiol
Title: CFTR-associated ligand is a negative regulator of Mrp2 expression.
Volume: 312
Issue: 1
Pages: C40-C46
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Publication
29742432 | J:271142
First Author: Renga G
Year: 2018
Journal: Cell Rep
Title: IL-9 and Mast Cells Are Key Players of Candida albicans Commensalism and Pathogenesis in the Gut.
Volume: 23
Issue: 6
Pages: 1767-1778
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Publication
30653340 | J:273402
First Author: Bertolini A
Year: 2019
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Defective FXR-FGF15 signaling and bile acid homeostasis in cystic fibrosis mice can be restored by the laxative polyethylene glycol.
Volume: 316
Issue: 3
Pages: G404-G411
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Publication
25158854 | J:232152
First Author: Nedvetsky PI
Year: 2014
Journal: Dev Cell
Title: Parasympathetic innervation regulates tubulogenesis in the developing salivary gland.
Volume: 30
Issue: 4
Pages: 449-62
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Publication
28552668 | J:272682
First Author: Grassmé H
Year: 2017
Journal: Cell Host Microbe
Title: β1-Integrin Accumulates in Cystic Fibrosis Luminal Airway Epithelial Membranes and Decreases Sphingosine, Promoting Bacterial Infections.
Volume: 21
Issue: 6
Pages: 707-718.e8
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Publication
15731086 | J:151458
First Author: González-Zorn B
Year: 2005
Journal: Infect Immun
Title: Bacterial and host factors implicated in nasal carriage of methicillin-resistant Staphylococcus aureus in mice.
Volume: 73
Issue: 3
Pages: 1847-51
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Publication
22314397 | J:323267
 
First Author: Entezari M
Year: 2012
Journal: Mol Med
Title: Inhibition of high-mobility group box 1 protein (HMGB1) enhances bacterial clearance and protects against Pseudomonas Aeruginosa pneumonia in cystic fibrosis.
Volume: 18
Pages: 477-85
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Publication
26199136 | J:323268
First Author: Scirpo R
Year: 2015
Journal: Hepatology
Title: Stimulation of nuclear receptor peroxisome proliferator-activated receptor-γ limits NF-κB-dependent inflammation in mouse cystic fibrosis biliary epithelium.
Volume: 62
Issue: 5
Pages: 1551-62
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Publication
25239913 | J:222194
First Author: Chillappagari S
Year: 2014
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Impaired TLR4 and HIF expression in cystic fibrosis bronchial epithelial cells downregulates hemeoxygenase-1 and alters iron homeostasis in vitro.
Volume: 307
Issue: 10
Pages: L791-9
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Publication
34847078 | J:320491
 
First Author: van de Veerdonk FL
Year: 2022
Journal: J Clin Invest
Title: Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy.
Volume: 132
Issue: 2
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Publication
25500839 | J:225122
First Author: Palomo J
Year: 2014
Journal: PLoS One
Title: Role of IL-1β in experimental cystic fibrosis upon P. aeruginosa infection.
Volume: 9
Issue: 12
Pages: e114884
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Publication
20929715 | J:323258
First Author: Tye CE
Year: 2010
Journal: J Dent Res
Title: Altered ion-responsive gene expression in Mmp20 null mice.
Volume: 89
Issue: 12
Pages: 1421-6
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Publication
21303908 | J:171142
First Author: Wu D
Year: 2011
Journal: J Biol Chem
Title: Interleukin-13 (IL-13)/IL-13 receptor alpha1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent Cl- secretion.
Volume: 286
Issue: 15
Pages: 13357-69
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Publication
11130975 | J:66063
First Author: Brouillette JA
Year: 2000
Journal: Mamm Genome
Title: Estimate of nucleotide diversity in dogs with a pool-and-sequence method.
Volume: 11
Issue: 12
Pages: 1079-86
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Publication
1385049 | J:3210
First Author: Siegel D
Year: 1992
Journal: Cytogenet Cell Genet
Title: Localization of the cystic fibrosis transmembrane conductance regulator (Cftr) to mouse chromosome 6.
Volume: 61
Issue: 3
Pages: 184-5
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Publication
8547326 | J:30592
First Author: Chianale J
Year: 1995
Journal: Biochim Biophys Acta
Title: Differences between nuclear run-off and mRNA levels for multidrug resistance gene expression in the cephalocaudal axis of the mouse intestine.
Volume: 1264
Issue: 3
Pages: 369-76
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Publication
8268652 | J:15209
First Author: Chua SC
Year: 1993
Journal: Mamm Genome
Title: The little (lit) mutation cosegregates with the growth hormone releasing factor receptor on mouse chromosome 6.
Volume: 4
Issue: 10
Pages: 555-9
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Publication
26972847 | J:236557
 
First Author: Iannitti RG
Year: 2016
Journal: Nat Commun
Title: IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis.
Volume: 7
Pages: 10791
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Publication
35581352 | J:326260
First Author: Di Pietro C
Year: 2022
Journal: Exp Mol Med
Title: Recruitment of monocytes primed to express heme oxygenase-1 ameliorates pathological lung inflammation in cystic fibrosis.
Volume: 54
Issue: 5
Pages: 639-652
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Publication
10666041 | J:60359
First Author: Shull GE
Year: 2000
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Lessons from genetically engineered animal models VIII. Absorption and secretion of ions in the gastrointestinal tract.
Volume: 278
Issue: 2
Pages: G185-90
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Publication
12834868 | J:84416
First Author: Chazaud C
Year: 2003
Journal: Mech Dev
Title: Retinoic acid signaling regulates murine bronchial tubule formation.
Volume: 120
Issue: 6
Pages: 691-700
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Publication
26077908 | J:223752
First Author: Cai T
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Dysplastic spondylolysis is caused by mutations in the diastrophic dysplasia sulfate transporter gene.
Volume: 112
Issue: 26
Pages: 8064-9
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Publication
11287183 | J:69279
First Author: Mailleux AA
Year: 2001
Journal: Mech Dev
Title: Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis.
Volume: 102
Issue: 1-2
Pages: 81-94
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Publication
21438071 | J:171626
First Author: Li S
Year: 2011
Journal: Dev Dyn
Title: Foxn4 influences alveologenesis during lung development.
Volume: 240
Issue: 6
Pages: 1512-7
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Publication
33692105 | J:306396
 
First Author: Kim YS
Year: 2021
Journal: Sci Adv
Title: Deciphering epiblast lumenogenesis reveals proamniotic cavity control of embryo growth and patterning.
Volume: 7
Issue: 11
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Publication
28994389 | J:249431
   
First Author: Honda K
Year: 2017
Journal: Elife
Title: Molecular architecture underlying fluid absorption by the developing inner ear.
Volume: 6
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Publication
32286221 | J:306246
   
First Author: He M
Year: 2020
Journal: Elife
Title: Chloride channels regulate differentiation and barrier functions of the mammalian airway.
Volume: 9
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Publication
9006067 | J:38383
First Author: Bellusci S
Year: 1997
Journal: Development
Title: Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis.
Volume: 124
Issue: 1
Pages: 53-63
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Publication
11707776 | J:72841
First Author: Walentinsson A
Year: 2001
Journal: Mamm Genome
Title: A dual-color FISH gene map of the proximal region of rat Chromosome 4 and comparative analysis in human and mouse.
Volume: 12
Issue: 12
Pages: 900-8
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Title: The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse.
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Protein
P26361
Organism: Mus musculus/domesticus
Length: 1476  
Fragment?: false
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Title: Gene Ontology annotation through association of InterPro records with GO terms
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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