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Search results 801 to 841 out of 841 for Cspg4

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Type Details Score
Strain
Attribute String: transgenic, mutant strain, congenic
Strain
Attribute String: congenic, mutant strain, transgenic
Publication  
First Author: Huang M
Year: 2022
Journal: Cancer Lett
Title: Tumor perivascular cell-derived extracellular vesicles promote angiogenesis via the Gas6/Axl pathway.
Volume: 524
Pages: 131-143
Allele
Name: transgene insertion H, Dwight E Bergles
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: congenic, mutant strain, transgenic
Allele
Name: transgene insertion, Berislav V Zlokovic
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Genotype
Symbol: Cspg4/Cspg4<+>
Background: involves: 129P2/OlaHsd * C57BL/6N
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Cspg4-cre)1Rkl/?
Background: involves: 129X1/SvJ * FVB
Zygosity: cn
Has Mutant Allele: true
Strain
Attribute String: congenic, mutant strain, transgenic
Publication
First Author: Hughes EG
Year: 2013
Journal: Nat Neurosci
Title: Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain.
Volume: 16
Issue: 6
Pages: 668-76
Publication
First Author: Cooke VG
Year: 2012
Journal: Cancer Cell
Title: Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway.
Volume: 21
Issue: 1
Pages: 66-81
Publication
First Author: Karmouch J
Year: 2017
Journal: Circ Res
Title: Distinct Cellular Basis for Early Cardiac Arrhythmias, the Cardinal Manifestation of Arrhythmogenic Cardiomyopathy, and the Skin Phenotype of Cardiocutaneous Syndromes.
Volume: 121
Issue: 12
Pages: 1346-1359
Publication
First Author: Bhattacharyya S
Year: 2023
Journal: J Alzheimers Dis Rep
Title: Increased Cerebral Serum Amyloid A2 and Parameters of Oxidation in Arylsulfatase B (N-Acetylgalactosamine-4-Sulfatase)-Null Mice.
Volume: 7
Issue: 1
Pages: 527-534
Publication
First Author: Liu Y
Year: 2022
Journal: J Lipid Res
Title: Loss of ABCA8B decreases myelination by reducing oligodendrocyte precursor cells in mice.
Volume: 63
Issue: 1
Pages: 100147
Publication
First Author: Nakashima K
Year: 2023
Journal: Commun Biol
Title: POT1a deficiency in mesenchymal niches perturbs B-lymphopoiesis.
Volume: 6
Issue: 1
Pages: 996
Publication
First Author: Fukushi J
Year: 2004
Journal: Mol Biol Cell
Title: NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin.
Volume: 15
Issue: 8
Pages: 3580-90
Publication
First Author: Li J
Year: 2003
Journal: Dev Biol
Title: The muscle integrin binding protein (MIBP) interacts with alpha7beta1 integrin and regulates cell adhesion and laminin matrix deposition.
Volume: 261
Issue: 1
Pages: 209-19
Protein Domain
Type: Family
Description: Integrins are the major metazoan receptors for cell adhesion to extracellular matrix proteins and, in vertebrates, also play important roles in certain cell-cell adhesions, make transmembrane connections to the cytoskeleton and activate many intracellular signalling pathways [, ]. An integrin receptor is a heterodimer composed of alpha and beta subunits. Each subunit crosses the membrane once, with most of the polypeptide residing in the extracellular space, and has twoshort cytoplasmic domains. Some members of this family have EGF repeats at the C terminus and also have a vWA domain inserted within the integrin domain at the N terminus.Most integrins recognise relatively short peptide motifs, and in general require an acidic amino acid to be present. Ligand specificity depends upon both the alpha and beta subunits []. There are at least 18 types of alpha and 8 types of beta subunits recognised in humans []. Each alpha subunit tends to associate only with one type of beta subunit, but there are exceptions to this rule []. Each association of alpha and beta subunits has its own binding specificity and signalling properties. Many integrins require activation on the cell surface before they can bind ligands. Integrins frequently intercommunicate, and binding at one integrin receptor activate or inhibit another.This entry represent integrin beta-1. Beta-1 integrin associates with alpha subunits to form receptor complexes that bind a variety of ligands. Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Alpha7beta1 integrin regulates cell adhesion and laminin matrix deposition []. Integrin alpha-4/beta-1 is a receptor for VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4 and has a role in endothelial cell motility and angiogenesis [].
Publication
First Author: Hughes EG
Year: 2018
Journal: Nat Neurosci
Title: Myelin remodeling through experience-dependent oligodendrogenesis in the adult somatosensory cortex.
Volume: 21
Issue: 5
Pages: 696-706
Publication  
First Author: Chung SH
Year: 2015
Journal: Cell Death Dis
Title: The p38α mitogen-activated protein kinase is a key regulator of myelination and remyelination in the CNS.
Volume: 6
Pages: e1748
Publication  
First Author: Nelson AR
Year: 2020
Journal: Front Aging Neurosci
Title: Channelrhodopsin Excitation Contracts Brain Pericytes and Reduces Blood Flow in the Aging Mouse Brain in vivo.
Volume: 12
Pages: 108
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdgfrb-FLP1,Cspg4-cre/ERT2)#Bvz/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Wu M
Year: 2022
Journal: J Neuroinflammation
Title: The effect of topical decorin on temporal changes to corneal immune cells after epithelial abrasion.
Volume: 19
Issue: 1
Pages: 90
Publication
First Author: Nikolakopoulou AM
Year: 2019
Journal: Nat Neurosci
Title: Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss.
Volume: 22
Issue: 7
Pages: 1089-1098
Protein
Organism: Mus musculus/domesticus
Length: 58  
Fragment?: false
Publication
First Author: LeBleu VS
Year: 2013
Journal: Nat Med
Title: Origin and function of myofibroblasts in kidney fibrosis.
Volume: 19
Issue: 8
Pages: 1047-53
Publication
First Author: Pekayvaz K
Year: 2023
Journal: Immunity
Title: Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation.
Volume: 56
Issue: 10
Pages: 2325-2341.e15
Publication
First Author: Mastorakos P
Year: 2021
Journal: Nat Neurosci
Title: Temporally distinct myeloid cell responses mediate damage and repair after cerebrovascular injury.
Volume: 24
Issue: 2
Pages: 245-258
Publication
First Author: Kenney HM
Year: 2020
Journal: Sci Rep
Title: Lineage tracing reveals evidence of a popliteal lymphatic muscle progenitor cell that is distinct from skeletal and vascular muscle progenitors.
Volume: 10
Issue: 1
Pages: 18088
Publication
First Author: Liu YJ
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Cspg4(high) microglia contribute to microgliosis during neurodegeneration.
Volume: 120
Issue: 8
Pages: e2210643120
Protein
Organism: Mus musculus/domesticus
Length: 92  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: true
Publication  
First Author: LeBleu VS
Year: 2024
Journal: Life Sci Alliance
Title: Genetic reprogramming with stem cells regenerates glomerular epithelial podocytes in Alport syndrome.
Volume: 7
Issue: 6
Publication
First Author: Kim JE
Year: 2020
Journal: Nat Commun
Title: Single cell and genetic analyses reveal conserved populations and signaling mechanisms of gastrointestinal stromal niches.
Volume: 11
Issue: 1
Pages: 334
Protein
Organism: Mus musculus/domesticus
Length: 798  
Fragment?: false
Publication
First Author: Demetriou MC
Year: 2004
Journal: J Cell Biochem
Title: Integrin clipping: a novel adhesion switch?
Volume: 91
Issue: 1
Pages: 26-35
Publication
First Author: Cheresh DA
Year: 1989
Journal: Cell
Title: A novel vitronectin receptor integrin (alpha v beta x) is responsible for distinct adhesive properties of carcinoma cells.
Volume: 57
Issue: 1
Pages: 59-69
Publication  
First Author: Arnaout MA
Year: 2002
Journal: Immunol Rev
Title: Integrin structure: new twists and turns in dynamic cell adhesion.
Volume: 186
Pages: 125-40
Publication
First Author: Hynes RO
Year: 2002
Journal: Cell
Title: Integrins: bidirectional, allosteric signaling machines.
Volume: 110
Issue: 6
Pages: 673-87
Publication
First Author: Bökel C
Year: 2002
Journal: Dev Cell
Title: Integrins in development: moving on, responding to, and sticking to the extracellular matrix.
Volume: 3
Issue: 3
Pages: 311-21
Publication      
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME