Type |
Details |
Score |
Publication |
First Author: |
Burger D |
Year: |
2009 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Role of heme oxygenase-1 in the cardioprotective effects of erythropoietin during myocardial ischemia and reperfusion. |
Volume: |
296 |
Issue: |
1 |
Pages: |
H84-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Soliz J |
Year: |
2009 |
Journal: |
Am J Physiol Regul Integr Comp Physiol |
Title: |
Sex-dependent regulation of hypoxic ventilation in mice and humans is mediated by erythropoietin. |
Volume: |
296 |
Issue: |
6 |
Pages: |
R1837-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu W |
Year: |
2011 |
Journal: |
Exp Neurol |
Title: |
Neuroprotective potential of erythropoietin and its derivative carbamylated erythropoietin in periventricular leukomalacia. |
Volume: |
230 |
Issue: |
2 |
Pages: |
227-39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Torrano V |
Year: |
2011 |
Journal: |
Blood |
Title: |
ETV6-RUNX1 promotes survival of early B lineage progenitor cells via a dysregulated erythropoietin receptor. |
Volume: |
118 |
Issue: |
18 |
Pages: |
4910-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sakoda Y |
Year: |
2011 |
Journal: |
J Clin Invest |
Title: |
Herpesvirus entry mediator regulates hypoxia-inducible factor-1α and erythropoiesis in mice. |
Volume: |
121 |
Issue: |
12 |
Pages: |
4810-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zafiriou MP |
Year: |
2014 |
Journal: |
Stem Cells |
Title: |
Erythropoietin responsive cardiomyogenic cells contribute to heart repair post myocardial infarction. |
Volume: |
32 |
Issue: |
9 |
Pages: |
2480-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wiedenmann T |
Year: |
2015 |
Journal: |
Mol Immunol |
Title: |
Erythropoietin acts as an anti-inflammatory signal on murine mast cells. |
Volume: |
65 |
Issue: |
1 |
Pages: |
68-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sargin D |
Year: |
2011 |
Journal: |
BMC Biol |
Title: |
Expression of constitutively active erythropoietin receptor in pyramidal neurons of cortex and hippocampus boosts higher cognitive functions in mice. |
Volume: |
9 |
|
Pages: |
27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gruneberg D |
Year: |
2016 |
Journal: |
Exp Neurol |
Title: |
Neuronal prolyl-4-hydroxylase 2 deficiency improves cognitive abilities in a murine model of cerebral hypoperfusion. |
Volume: |
286 |
|
Pages: |
93-106 |
|
•
•
•
•
•
|
Publication |
First Author: |
Flamme I |
Year: |
2017 |
Journal: |
PLoS One |
Title: |
FGF23 expression in rodents is directly induced via erythropoietin after inhibition of hypoxia inducible factor proline hydroxylase. |
Volume: |
12 |
Issue: |
10 |
Pages: |
e0186979 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu ML |
Year: |
2018 |
Journal: |
J Neurochem |
Title: |
Erythropoietin regulates the expression of dimeric form of acetylcholinesterase during differentiation of erythroblast. |
Volume: |
146 |
Issue: |
4 |
Pages: |
390-402 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dmytriyeva O |
Year: |
2019 |
Journal: |
Neurobiol Aging |
Title: |
Short erythropoietin-derived peptide enhances memory, improves long-term potentiation, and counteracts amyloid beta-induced pathology. |
Volume: |
81 |
|
Pages: |
88-101 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dey S |
Year: |
2020 |
Journal: |
JCI Insight |
Title: |
Sex-specific brain erythropoietin regulation of mouse metabolism and hypothalamic inflammation. |
Volume: |
5 |
Issue: |
5 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Li J |
Year: |
2021 |
Journal: |
Cell Death Dis |
Title: |
CHBP induces stronger immunosuppressive CD127(+) M-MDSC via erythropoietin receptor. |
Volume: |
12 |
Issue: |
2 |
Pages: |
177 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang W |
Year: |
2021 |
Journal: |
Front Immunol |
Title: |
Extracellular CIRP-Impaired Rab26 Restrains EPOR-Mediated Macrophage Polarization in Acute Lung Injury. |
Volume: |
12 |
|
Pages: |
768435 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bulut GB |
Year: |
2013 |
Journal: |
Blood |
Title: |
Cbl ubiquitination of p85 is essential for Epo-induced EpoR endocytosis. |
Volume: |
122 |
Issue: |
24 |
Pages: |
3964-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Awida Z |
Year: |
2022 |
Journal: |
Int J Mol Sci |
Title: |
Erythropoietin Receptor (EPOR) Signaling in the Osteoclast Lineage Contributes to EPO-Induced Bone Loss in Mice. |
Volume: |
23 |
Issue: |
19 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Doyle AD |
Year: |
2013 |
Journal: |
Blood |
Title: |
Expression of the secondary granule proteins major basic protein 1 (MBP-1) and eosinophil peroxidase (EPX) is required for eosinophilopoiesis in mice. |
Volume: |
122 |
Issue: |
5 |
Pages: |
781-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Waskow C |
Year: |
2002 |
Journal: |
Immunity |
Title: |
Viable c-Kit(W/W) mutants reveal pivotal role for c-kit in the maintenance of lymphopoiesis. |
Volume: |
17 |
Issue: |
3 |
Pages: |
277-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
O'Connell AE |
Year: |
2011 |
Journal: |
Infect Immun |
Title: |
Major basic protein from eosinophils and myeloperoxidase from neutrophils are required for protective immunity to Strongyloides stercoralis in mice. |
Volume: |
79 |
Issue: |
7 |
Pages: |
2770-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suzuki S |
Year: |
2016 |
Journal: |
J Allergy Clin Immunol |
Title: |
The potential for repositioning antithyroid agents as antiasthma drugs. |
Volume: |
138 |
Issue: |
5 |
Pages: |
1458-1461.e8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gebreselassie NG |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
Eosinophils preserve parasitic nematode larvae by regulating local immunity. |
Volume: |
188 |
Issue: |
1 |
Pages: |
417-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marx C |
Year: |
2019 |
Journal: |
Blood |
Title: |
Eosinophil-platelet interactions promote atherosclerosis and stabilize thrombosis with eosinophil extracellular traps. |
Volume: |
134 |
Issue: |
21 |
Pages: |
1859-1872 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
145
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
99
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Peroxidases are haem-containing enzymes that use hydrogen peroxide as the electron acceptor to catalyse a number of oxidative reactions.Peroxidases are found in bacteria, fungi, plants and animals. On the basis of sequence similarity, a number of animal haem peroxidases can be categorised as members of a superfamily: myeloperoxidase (MPO); eosinophil peroxidase (EPO); lactoperoxidase (LPO); thyroid peroxidase (TPO); prostaglandin H synthase (PGHS); and peroxidasin [, , ]. MPO plays a major role in the oxygen-dependent microbicidal system of neutrophils. EPO from eosinophilic granulocytes participates in immunological reactions, and potentiates tumor necrosis factor (TNF) production and hydrogen peroxide release by human monocyte-derived macrophages [, ]. In the main, MPO (and possibly EPO) utilises Cl-ions and H2O2to form hypochlorous acid (HOCl), which can effectively kill bacteria or parasites. In secreted fluids, LPO catalyses the oxidation of thiocyanate ions (SCN-) by H2O2, producing the weak oxidising agent hypothiocyanite (OSCN-), which has bacteriostatic activity []. TPO uses I-ions and H2O2to generate iodine, and plays a central role in the biosynthesis of thyroid hormones T(3) and T(4). To date, the 3D structures of MPO and PGHS have been reported. MPO is a homodimer: each monomer consists of a light (A or B) and a heavy (C or D) chain resulting from post-translational excision of 6 residues from the common precursor. Monomers are linked by a single inter-chain disulphide. Each monomer includes a bound calcium ion []. PGHS exists as a symmetric dimer, each monomer of which consists of 3 domains: an N-terminal epidermal growth factor (EGF) like module; a membrane-binding domain; and a large C-terminal catalytic domain containing the cyclooxygenase and the peroxidase active sites. The catalytic domain shows striking structural similarity to MPO. The cyclooxygenase active site, which catalyses the formation of prostaglandin G2 (PGG2) from arachidonic acid, resides at the apex of a long hydrophobic channel, extending from the membrane-binding domain to the centre of the molecule. The peroxidase active site, which catalyses the reduction of PGG2 to PGH2, is located on the other side of the molecule, at the haem binding site []. Both MPO and the catalytic domain of PGHS are mainly α-helical, 19 helices being identified as topologically and spatially equivalent; PGHS contains 5 additional N-terminal helices that have no equivalent in MPO. In both proteins, three Asn residues in each monomer are glycosylated. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Homologous_superfamily |
Description: |
Peroxidases are haem-containing enzymes that use hydrogen peroxide as the electron acceptor to catalyse a number of oxidative reactions.Peroxidases are found in bacteria, fungi, plants and animals. On the basis of sequence similarity, a number of animal haem peroxidases can be categorised as members of a superfamily: myeloperoxidase (MPO); eosinophil peroxidase (EPO); lactoperoxidase (LPO); thyroid peroxidase (TPO); prostaglandin H synthase (PGHS); and peroxidasin [, , ]. MPO plays a major role in the oxygen-dependent microbicidal system of neutrophils. EPO from eosinophilic granulocytes participates in immunological reactions, and potentiates tumor necrosis factor (TNF) production and hydrogen peroxide release by human monocyte-derived macrophages [, ]. In the main, MPO (and possibly EPO) utilises Cl-ions and H2O2to form hypochlorous acid (HOCl), which can effectively kill bacteria or parasites. In secreted fluids, LPO catalyses the oxidation of thiocyanate ions (SCN-) by H2O2, producing the weak oxidising agent hypothiocyanite (OSCN-), which has bacteriostatic activity []. TPO uses I-ions and H2O2to generate iodine, and plays a central role in the biosynthesis of thyroid hormones T(3) and T(4). To date, the 3D structures of MPO and PGHS have been reported. MPO is a homodimer: each monomer consists of a light (A or B) and a heavy (C or D) chain resulting from post-translational excision of 6 residues from the common precursor. Monomers are linked by a single inter-chain disulphide. Each monomer includes a bound calcium ion []. PGHS exists as a symmetric dimer, each monomer of which consists of 3 domains: an N-terminal epidermal growth factor (EGF) like module; a membrane-binding domain; and a large C-terminal catalytic domain containing the cyclooxygenase and the peroxidase active sites. The catalytic domain shows striking structural similarity to MPO. The cyclooxygenase active site, which catalyses the formation of prostaglandin G2 (PGG2) from arachidonic acid, resides at the apex of a long hydrophobic channel, extending from the membrane-binding domain to the centre of the molecule. The peroxidase active site, which catalyses the reduction of PGG2 to PGH2, is located on the other side of the molecule, at the haem binding site []. Both MPO and the catalytic domain of PGHS are mainly α-helical, 19 helices being identified as topologically and spatially equivalent; PGHS contains 5 additional N-terminal helices that have no equivalent in MPO. In both proteins, three Asn residues in each monomer are glycosylated. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
718
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
718
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
166
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
710
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
718
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
183
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
710
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
718
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
138
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Kimura S |
Year: |
1989 |
Journal: |
Biochemistry |
Title: |
Structure of the human thyroid peroxidase gene: comparison and relationship to the human myeloperoxidase gene. |
Volume: |
28 |
Issue: |
10 |
Pages: |
4481-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wever R |
Year: |
1982 |
Journal: |
Biochim Biophys Acta |
Title: |
The peroxidation of thiocyanate catalysed by myeloperoxidase and lactoperoxidase. |
Volume: |
709 |
Issue: |
2 |
Pages: |
212-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Spessotto P |
Year: |
1995 |
Journal: |
Eur J Immunol |
Title: |
Human eosinophil peroxidase enhances tumor necrosis factor and hydrogen peroxide release by human monocyte-derived macrophages. |
Volume: |
25 |
Issue: |
5 |
Pages: |
1366-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zeng J |
Year: |
1992 |
Journal: |
J Mol Biol |
Title: |
X-ray crystal structure of canine myeloperoxidase at 3 A resolution. |
Volume: |
226 |
Issue: |
1 |
Pages: |
185-207 |
|
•
•
•
•
•
|
Publication |
First Author: |
Picot D |
Year: |
1994 |
Journal: |
Nature |
Title: |
The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1. |
Volume: |
367 |
Issue: |
6460 |
Pages: |
243-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kimura S |
Year: |
1988 |
Journal: |
Proteins |
Title: |
Human myeloperoxidase and thyroid peroxidase, two enzymes with separate and distinct physiological functions, are evolutionarily related members of the same gene family. |
Volume: |
3 |
Issue: |
2 |
Pages: |
113-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoshimura A |
Year: |
1996 |
Journal: |
EMBO J |
Title: |
Mouse oncostatin M: an immediate early gene induced by multiple cytokines through the JAK-STAT5 pathway. |
Volume: |
15 |
Issue: |
5 |
Pages: |
1055-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Van Zant G |
Year: |
1989 |
Journal: |
Exp Hematol |
Title: |
Hematologic abnormalities of the immunodeficient mouse mutant, viable motheaten (mev). |
Volume: |
17 |
Issue: |
2 |
Pages: |
81-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koulnis M |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
Negative autoregulation by Fas stabilizes adult erythropoiesis and accelerates its stress response. |
Volume: |
6 |
Issue: |
7 |
Pages: |
e21192 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wong KS |
Year: |
1999 |
Journal: |
Oncogene |
Title: |
Loss of p53 in F-MuLV induced-erythroleukemias accelerates the acquisition of mutational events that confers immortality and growth factor independence. |
Volume: |
18 |
Issue: |
40 |
Pages: |
5525-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Porpiglia E |
Year: |
2012 |
Journal: |
PLoS Biol |
Title: |
Stat5 signaling specifies basal versus stress erythropoietic responses through distinct binary and graded dynamic modalities. |
Volume: |
10 |
Issue: |
8 |
Pages: |
e1001383 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin CS |
Year: |
1996 |
Journal: |
Genes Dev |
Title: |
Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis. |
Volume: |
10 |
Issue: |
2 |
Pages: |
154-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee HY |
Year: |
2015 |
Journal: |
Nature |
Title: |
PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal. |
Volume: |
522 |
Issue: |
7557 |
Pages: |
474-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Subramanian A |
Year: |
2006 |
Journal: |
Leuk Res |
Title: |
Mutation of the Lyn tyrosine kinase delays the progression of Friend virus induced erythroleukemia without affecting susceptibility. |
Volume: |
30 |
Issue: |
9 |
Pages: |
1141-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zaleskas VM |
Year: |
2006 |
Journal: |
PLoS One |
Title: |
Molecular pathogenesis and therapy of polycythemia induced in mice by JAK2 V617F. |
Volume: |
1 |
|
Pages: |
e18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Choi D |
Year: |
2011 |
Journal: |
Lab Invest |
Title: |
Vhl is required for normal pancreatic β cell function and the maintenance of β cell mass with age in mice. |
Volume: |
91 |
Issue: |
4 |
Pages: |
527-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vannucchi AM |
Year: |
2001 |
Journal: |
Blood |
Title: |
Accentuated response to phenylhydrazine and erythropoietin in mice genetically impaired for their GATA-1 expression (GATA-1(low) mice). |
Volume: |
97 |
Issue: |
10 |
Pages: |
3040-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ledford JG |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Surfactant protein-A suppresses eosinophil-mediated killing of Mycoplasma pneumoniae in allergic lungs. |
Volume: |
7 |
Issue: |
2 |
Pages: |
e32436 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chavez JC |
Year: |
2006 |
Journal: |
J Neurosci |
Title: |
The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes. |
Volume: |
26 |
Issue: |
37 |
Pages: |
9471-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lourhmati A |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Age-dependent astroglial vulnerability to hypoxia and glutamate: the role for erythropoietin. |
Volume: |
8 |
Issue: |
10 |
Pages: |
e77182 |
|
•
•
•
•
•
|
Publication |
First Author: |
Al-Onaizi MA |
Year: |
2022 |
Journal: |
Brain Behav Immun |
Title: |
Early monocyte modulation by the non-erythropoietic peptide ARA 290 decelerates AD-like pathology progression. |
Volume: |
99 |
|
Pages: |
363-382 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chang R |
Year: |
2018 |
Journal: |
Mol Pharm |
Title: |
Brain Penetrating Bifunctional Erythropoietin-Transferrin Receptor Antibody Fusion Protein for Alzheimer's Disease. |
Volume: |
15 |
Issue: |
11 |
Pages: |
4963-4973 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun J |
Year: |
2019 |
Journal: |
Alzheimers Dement (N Y) |
Title: |
Hematologic safety of chronic brain-penetrating erythropoietin dosing in APP/PS1 mice. |
Volume: |
5 |
|
Pages: |
627-636 |
|
•
•
•
•
•
|
Publication |
First Author: |
Krijt J |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Effect of iron overload and iron deficiency on liver hemojuvelin protein. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e37391 |
|
•
•
•
•
•
|
Publication |
First Author: |
Votava JA |
Year: |
2022 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Dysregulation of the sensory and regulatory pathways controlling cellular iron metabolism in unilateral obstructive nephropathy. |
Volume: |
322 |
Issue: |
1 |
Pages: |
F89-F103 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsui AK |
Year: |
2014 |
Journal: |
Am J Physiol Regul Integr Comp Physiol |
Title: |
Differential HIF and NOS responses to acute anemia: defining organ-specific hemoglobin thresholds for tissue hypoxia. |
Volume: |
307 |
Issue: |
1 |
Pages: |
R13-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu Y |
Year: |
2023 |
Journal: |
Front Immunol |
Title: |
HBSP improves kidney ischemia-reperfusion injury and promotes repair in properdin deficient mice via enhancing phagocytosis of tubular epithelial cells. |
Volume: |
14 |
|
Pages: |
1183768 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee J |
Year: |
2021 |
Journal: |
Mol Metab |
Title: |
Erythropoietin reduces fat mass in female mice lacking estrogen receptor alpha. |
Volume: |
45 |
|
Pages: |
101142 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang Y |
Year: |
2022 |
Journal: |
Int Immunopharmacol |
Title: |
Knockdown of CCR3 gene inhibits Proliferation, migration and degranulation of eosinophils in mice by downregulating the PI3K/Akt pathway. |
Volume: |
113 |
Issue: |
Pt B |
Pages: |
109439 |
|
•
•
•
•
•
|
Publication |
First Author: |
Woods SL |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Differential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element. Cross-talk between basic helix-loop-helix/per-Arnt-Sim homology transcription factors. |
Volume: |
277 |
Issue: |
12 |
Pages: |
10236-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Beckman BS |
Year: |
1996 |
Journal: |
Biochem J |
Title: |
Molecular species of phospholipids in a murine stem-cell line responsive to erythropoietin. |
Volume: |
314 ( Pt 3) |
|
Pages: |
861-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miura Y |
Year: |
1994 |
Journal: |
J Biol Chem |
Title: |
Activation of the mitogen-activated protein kinase pathway by the erythropoietin receptor. |
Volume: |
269 |
Issue: |
47 |
Pages: |
29962-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wendling F |
Year: |
1989 |
Journal: |
Blood |
Title: |
Factor-independent erythropoietic progenitor cells in leukemia induced by the myeloproliferative leukemia virus. |
Volume: |
73 |
Issue: |
5 |
Pages: |
1161-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ruscetti S |
Year: |
1992 |
Journal: |
J Virol |
Title: |
Induction of erythropoietin responsiveness in murine hematopoietic cells by the gag-myb-ets-containing ME26 virus. |
Volume: |
66 |
Issue: |
1 |
Pages: |
20-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bell SJ |
Year: |
1996 |
Journal: |
Cell Immunol |
Title: |
A role for Th2 T-memory cells in early airway obstruction. |
Volume: |
170 |
Issue: |
2 |
Pages: |
185-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chin H |
Year: |
1996 |
Journal: |
Blood |
Title: |
Physical and functional interactions between Stat5 and the tyrosine-phosphorylated receptors for erythropoietin and interleukin-3. |
Volume: |
88 |
Issue: |
12 |
Pages: |
4415-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin TS |
Year: |
1998 |
Journal: |
Oncol Res |
Title: |
Role of gp55 in restoring the sensitivity of Friend murine erythroleukemia cells to erythropoietin by exposure to dimethyl sulfoxide. |
Volume: |
10 |
Issue: |
4 |
Pages: |
175-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vannucchi AM |
Year: |
1999 |
Journal: |
J Cell Physiol |
Title: |
Increased expression of the distal, but not of the proximal, Gata1 transcripts during differentiation of primary erythroid cells. |
Volume: |
180 |
Issue: |
3 |
Pages: |
390-401 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang L |
Year: |
2005 |
Journal: |
Exp Hematol |
Title: |
Cytokine signals through STAT3 promote expression of granulocyte secondary granule proteins in 32D cells. |
Volume: |
33 |
Issue: |
3 |
Pages: |
308-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki T |
Year: |
2008 |
Journal: |
Neoplasia |
Title: |
Erythropoietin promotes the growth of tumors lacking its receptor and decreases survival of tumor-bearing mice by enhancing angiogenesis. |
Volume: |
10 |
Issue: |
9 |
Pages: |
932-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ueda F |
Year: |
2017 |
Journal: |
J Biol Chem |
Title: |
Three Tyrosine Residues in the Erythropoietin Receptor Are Essential for Janus Kinase 2 V617F Mutant-induced Tumorigenesis. |
Volume: |
292 |
Issue: |
5 |
Pages: |
1826-1846 |
|
•
•
•
•
•
|
Publication |
First Author: |
Willetts L |
Year: |
2018 |
Journal: |
Commun Biol |
Title: |
Vesicle-associated membrane protein 7-mediated eosinophil degranulation promotes allergic airway inflammation in mice. |
Volume: |
1 |
|
Pages: |
83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ochkur SI |
Year: |
2017 |
Journal: |
J Leukoc Biol |
Title: |
Frontline Science: Eosinophil-deficient MBP-1 and EPX double-knockout mice link pulmonary remodeling and airway dysfunction with type 2 inflammation. |
Volume: |
102 |
Issue: |
3 |
Pages: |
589-599 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
60
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
183
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
62
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
97
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
465
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Nagao M |
Year: |
1992 |
Journal: |
Biochim Biophys Acta |
Title: |
Nucleotide sequence of rat erythropoietin. |
Volume: |
1171 |
Issue: |
1 |
Pages: |
99-102 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin FK |
Year: |
1986 |
Journal: |
Gene |
Title: |
Monkey erythropoietin gene: cloning, expression and comparison with the human erythropoietin gene. |
Volume: |
44 |
Issue: |
2-3 |
Pages: |
201-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takeuchi M |
Year: |
1988 |
Journal: |
J Biol Chem |
Title: |
Comparative study of the asparagine-linked sugar chains of human erythropoietins purified from urine and the culture medium of recombinant Chinese hamster ovary cells. |
Volume: |
263 |
Issue: |
8 |
Pages: |
3657-63 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
602
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
604
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
604
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
403
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
561
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
488
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
602
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
602
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Caprara C |
Year: |
2014 |
Journal: |
Mol Vis |
Title: |
The erythropoietin receptor is not required for the development, function, and aging of rods and cells in the retinal periphery. |
Volume: |
20 |
|
Pages: |
307-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Padmanabhan N |
Year: |
2018 |
Journal: |
J Physiol |
Title: |
Abnormal folate metabolism causes age-, sex- and parent-of-origin-specific haematological defects in mice. |
Volume: |
596 |
Issue: |
18 |
Pages: |
4341-4360 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sheldon RA |
Year: |
2015 |
Journal: |
Dev Neurosci |
Title: |
Alteration in Downstream Hypoxia Gene Signaling in Neonatal Glutathione Peroxidase Overexpressing Mouse Brain after Hypoxia-Ischemia. |
Volume: |
37 |
Issue: |
4-5 |
Pages: |
398-406 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hafizi R |
Year: |
2022 |
Journal: |
Int J Mol Sci |
Title: |
Sphk1 and Sphk2 Differentially Regulate Erythropoietin Synthesis in Mouse Renal Interstitial Fibroblast-like Cells. |
Volume: |
23 |
Issue: |
11 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shibuya T |
Year: |
1982 |
Journal: |
J Exp Med |
Title: |
Erythroleukemia induction by Friend leukemia virus. A host gene locus controlling early anemia or polycythemia and the rate of proliferation of late erythroid cells. |
Volume: |
156 |
Issue: |
2 |
Pages: |
398-414 |
|
•
•
•
•
•
|