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Search results 801 to 886 out of 886 for Gjb2

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Type Details Score
Publication
25229253 | J:219904
First Author: Levit NA
Year: 2015
Journal: J Invest Dermatol
Title: Aberrant connexin26 hemichannels underlying keratitis-ichthyosis-deafness syndrome are potently inhibited by mefloquine.
Volume: 135
Issue: 4
Pages: 1033-1042
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Strain
MGI:7718071 | C57BL/6JSmoc-Gjb2<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6770782 | C57BL/6JSmoc-Gjb2<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein Coding Gene
MGI:107588 | Gjb6
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
2707 | GJB3
Type: gene
Organism: human
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Gene
10804 | GJB6
Type: gene
Organism: human
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Publication
20858605 | J:166362
First Author: Schütz M
Year: 2010
Journal: Hum Mol Genet
Title: The human deafness-associated connexin 30 T5M mutation causes mild hearing loss and reduces biochemical coupling among cochlear non-sensory cells in knock-in mice.
Volume: 19
Issue: 24
Pages: 4759-73
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Publication
23303923 | J:193913
First Author: Boulay AC
Year: 2013
Journal: J Neurosci
Title: Hearing is normal without connexin30.
Volume: 33
Issue: 2
Pages: 430-4
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Allele
Gjb6<tm1Mcsa> | MGI:5486676
Name: gap junction protein, beta 6; targeted mutation 1, Martine Cohen-Salmon
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Gjb6<tm1.1Mcsa> | MGI:5486677
Name: gap junction protein, beta 6; targeted mutation 1.1, Martine Cohen-Salmon
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:3849020 | B6.129P2-Gjb6<tm1Kwi>/Cnrm
Attribute String: congenic, targeted mutation, mutant strain
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Publication
12490528 | J:80917
First Author: Teubner B
Year: 2003
Journal: Hum Mol Genet
Title: Connexin30 (Gjb6)-deficiency causes severe hearing impairment and lack of endocochlear potential.
Volume: 12
Issue: 1
Pages: 13-21
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Publication
30103794 | J:311793
First Author: Fujita A
Year: 2018
Journal: J Neuroinflammation
Title: Connexin 30 deficiency attenuates A2 astrocyte responses and induces severe neurodegeneration in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride Parkinson's disease animal model.
Volume: 15
Issue: 1
Pages: 227
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Publication
29386634 | J:261295
First Author: Takeda H
Year: 2018
Journal: Sci Rep
Title: Engraftment of Human Pluripotent Stem Cell-derived Progenitors in the Inner Ear of Prenatal Mice.
Volume: 8
Issue: 1
Pages: 1941
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Publication
17400755 | J:120823
First Author: Cohen-Salmon M
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Connexin30 deficiency causes instrastrial fluid-blood barrier disruption within the cochlear stria vascularis.
Volume: 104
Issue: 15
Pages: 6229-34
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Publication
19116647 | J:144350
First Author: Chang Q
Year: 2008
Journal: PLoS One
Title: Gap junction mediated intercellular metabolite transfer in the cochlea is compromised in connexin30 null mice.
Volume: 3
Issue: 12
Pages: e4088
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Publication
22025386 | J:179771
First Author: Langer J
Year: 2012
Journal: Glia
Title: Gap junctions mediate intercellular spread of sodium between hippocampal astrocytes in situ.
Volume: 60
Issue: 2
Pages: 239-52
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Publication
30464764 | J:294127
 
First Author: Fang M
Year: 2018
Journal: Front Immunol
Title: Connexin 30 Deficiency Attenuates Chronic but Not Acute Phases of Experimental Autoimmune Encephalomyelitis Through Induction of Neuroprotective Microglia.
Volume: 9
Pages: 2588
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Publication
21075848 | J:167526
First Author: Mironova E
Year: 2011
Journal: J Biol Chem
Title: Diminished paracrine regulation of the epithelial Na+ channel by purinergic signaling in mice lacking connexin 30.
Volume: 286
Issue: 2
Pages: 1054-60
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Publication
12911759 | J:89971
First Author: Dere E
Year: 2003
Journal: Eur J Neurosci
Title: Connexin30-deficient mice show increased emotionality and decreased rearing activity in the open-field along with neurochemical changes.
Volume: 18
Issue: 3
Pages: 629-38
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Publication
33569381 | J:339394
 
First Author: Gentile G
Year: 2020
Journal: Front Cell Dev Biol
Title: miRNA and mRNA Profiling Links Connexin Deficiency to Deafness via Early Oxidative Damage in the Mouse Stria Vascularis.
Volume: 8
Pages: 616878
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Publication
32755449 | J:299620
First Author: Chen B
Year: 2020
Journal: Am J Physiol Cell Physiol
Title: Mechanisms of hearing loss and cell death in the cochlea of connexin mutant mice.
Volume: 319
Issue: 3
Pages: C569-C578
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Publication
19478095 | J:164622
First Author: Sipos A
Year: 2009
Journal: J Am Soc Nephrol
Title: Connexin 30 deficiency impairs renal tubular ATP release and pressure natriuresis.
Volume: 20
Issue: 8
Pages: 1724-32
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Publication
35573684 | J:339408
 
First Author: Zhang L
Year: 2022
Journal: Front Cell Dev Biol
Title: Virally Mediated Connexin 26 Expression in Postnatal Scala Media Significantly and Transiently Preserves Hearing in Connexin 30 Null Mice.
Volume: 10
Pages: 900416
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Publication
27785828 | J:237936
First Author: Langer J
Year: 2017
Journal: Glia
Title: Rapid sodium signaling couples glutamate uptake to breakdown of ATP in perivascular astrocyte endfeet.
Volume: 65
Issue: 2
Pages: 293-308
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Publication
23424196 | J:200590
First Author: Forge A
Year: 2013
Journal: J Cell Sci
Title: Connexin30-mediated intercellular communication plays an essential role in epithelial repair in the cochlea.
Volume: 126
Issue: Pt 7
Pages: 1703-12
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Genotype
Genotype
Symbol: Gjb6/Gjb6
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gjb6/Gjb6<+>
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gjb6/Gjb6
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gjb6/Gjb6
Background: involves: 129 * BALB/c * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
22891314 | J:188582
First Author: Rodriguez L
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Reduced phosphatidylinositol 4,5-bisphosphate synthesis impairs inner ear Ca2+ signaling and high-frequency hearing acquisition.
Volume: 109
Issue: 35
Pages: 14013-8
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Publication
20813869 | J:185905
First Author: Stockand JD
Year: 2010
Journal: J Am Soc Nephrol
Title: Purinergic inhibition of ENaC produces aldosterone escape.
Volume: 21
Issue: 11
Pages: 1903-11
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Publication
29234270 | J:256000
 
First Author: Zorzi V
Year: 2017
Journal: Front Mol Neurosci
Title: Mouse Panx1 Is Dispensable for Hearing Acquisition and Auditory Function.
Volume: 10
Pages: 379
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Publication
32700707 | J:339506
First Author: Mazzarda F
Year: 2020
Journal: Lab Chip
Title: Organ-on-chip model shows that ATP release through connexin hemichannels drives spontaneous Ca(2+) signaling in non-sensory cells of the greater epithelial ridge in the developing cochlea.
Volume: 20
Issue: 16
Pages: 3011-3023
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Publication
19679680 | J:172556
First Author: Gros D
Year: 2010
Journal: Cardiovasc Res
Title: Connexin 30 is expressed in the mouse sino-atrial node and modulates heart rate.
Volume: 85
Issue: 1
Pages: 45-55
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Genotype
Genotype
Symbol: Gjb6/Gjb6 Tg(Gjb2)1Xili/?
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
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Publication
30804003 | J:277076
 
First Author: Ceriani F
Year: 2019
Journal: EMBO J
Title: Coordinated calcium signalling in cochlear sensory and non-sensory cells refines afferent innervation of outer hair cells.
Volume: 38
Issue: 9
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Publication
36555685 | J:339756
 
First Author: Hashimoto Y
Year: 2022
Journal: Int J Mol Sci
Title: Connexin 30 Deficiency Ameliorates Disease Progression at the Early Phase in a Mouse Model of Amyotrophic Lateral Sclerosis by Suppressing Glial Inflammation.
Volume: 23
Issue: 24
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Publication
22399755 | J:182732
First Author: Huang C
Year: 2012
Journal: J Neurosci
Title: Critical role of connexin 43 in secondary expansion of traumatic spinal cord injury.
Volume: 32
Issue: 10
Pages: 3333-8
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Publication
25643695 | J:220853
First Author: Abudara V
Year: 2015
Journal: Glia
Title: Activated microglia impairs neuroglial interaction by opening Cx43 hemichannels in hippocampal astrocytes.
Volume: 63
Issue: 5
Pages: 795-811
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Publication
29475972 | J:258788
 
First Author: Ghézali G
Year: 2018
Journal: Development
Title: Connexin 30 controls astroglial polarization during postnatal brain development.
Volume: 145
Issue: 4
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Publication
30794327 | J:274333
First Author: Pannasch U
Year: 2019
Journal: Glia
Title: Astroglial Cx30 sustains neuronal population bursts independently of gap-junction mediated biochemical coupling.
Volume: 67
Issue: 6
Pages: 1104-1112
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Publication
24144139 | J:302960
 
First Author: Ceriani F
Year: 2013
Journal: Cell Commun Signal
Title: A rapid and sensitive assay of intercellular coupling by voltage imaging of gap junction networks.
Volume: 11
Pages: 78
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Publication
24584052 | J:212016
First Author: Pannasch U
Year: 2014
Journal: Nat Neurosci
Title: Connexin 30 sets synaptic strength by controlling astroglial synapse invasion.
Volume: 17
Issue: 4
Pages: 549-58
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Publication
22649229 | J:184971
First Author: Tress O
Year: 2012
Journal: J Neurosci
Title: Panglial gap junctional communication is essential for maintenance of myelin in the CNS.
Volume: 32
Issue: 22
Pages: 7499-518
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Publication
25698924 | J:242393
 
First Author: Boulay AC
Year: 2015
Journal: Front Cell Neurosci
Title: The Sarcoglycan complex is expressed in the cerebrovascular system and is specifically regulated by astroglial Cx30 channels.
Volume: 9
Pages: 9
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HT Experiment
GSE139587 | SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms (scRNA-seq: batch2)
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE131196 | SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
11741837 | J:73509
First Author: Liu XZ
Year: 2001
Journal: Hum Mol Genet
Title: Mutations in GJA1 (connexin 43) are associated with non-syndromic autosomal recessive deafness.
Volume: 10
Issue: 25
Pages: 2945-51
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Publication
12700168 | J:83168
First Author: Kudo T
Year: 2003
Journal: Hum Mol Genet
Title: Transgenic expression of a dominant-negative connexin26 causes degeneration of the organ of Corti and non-syndromic deafness.
Volume: 12
Issue: 9
Pages: 995-1004
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Publication
23843229 | J:203712
First Author: Diao H
Year: 2013
Journal: Biol Reprod
Title: Broad gap junction blocker carbenoxolone disrupts uterine preparation for embryo implantation in mice.
Volume: 89
Issue: 2
Pages: 31
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Publication
35110999 | J:319721
 
First Author: Chen J
Year: 2021
Journal: Front Cell Neurosci
Title: Connexin30-Deficiency Causes Mild Hearing Loss With the Reduction of Endocochlear Potential and ATP Release.
Volume: 15
Pages: 819194
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Publication
25356849 | J:228852
First Author: Chen J
Year: 2014
Journal: PLoS Genet
Title: Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss.
Volume: 10
Issue: 10
Pages: e1004688
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Publication
25259580 | J:222496
First Author: Kidokoro Y
Year: 2014
Journal: PLoS One
Title: Deficiency of transcription factor Brn4 disrupts cochlear gap junction plaques in a model of DFN3 non-syndromic deafness.
Volume: 9
Issue: 9
Pages: e108216
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Publication
34717927 | J:357144
 
First Author: Youkilis JC
Year: 2021
Journal: Exp Eye Res
Title: Single-cell RNA-sequencing analysis of the ciliary epithelium and contiguous tissues in the mouse eye.
Volume: 213
Pages: 108811
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Publication
12840073 | J:85065
First Author: Kretz M
Year: 2003
Journal: J Cell Sci
Title: Altered connexin expression and wound healing in the epidermis of connexin-deficient mice.
Volume: 116
Issue: Pt 16
Pages: 3443-52
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Publication
33589833 | J:305249
First Author: Wahis J
Year: 2021
Journal: Nat Neurosci
Title: Astrocytes mediate the effect of oxytocin in the central amygdala on neuronal activity and affective states in rodents.
Volume: 24
Issue: 4
Pages: 529-541
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Publication
19549869 | J:150822
First Author: Kunze A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Connexin expression by radial glia-like cells is required for neurogenesis in the adult dentate gyrus.
Volume: 106
Issue: 27
Pages: 11336-41
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Publication
22951907 | J:187682
First Author: Chen MJ
Year: 2012
Journal: Glia
Title: Astrocytic CX43 hemichannels and gap junctions play a crucial role in development of chronic neuropathic pain following spinal cord injury.
Volume: 60
Issue: 11
Pages: 1660-70
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Publication
26758214 | J:259994
First Author: Chever O
Year: 2016
Journal: Sci Signal
Title: Astroglial networks promote neuronal coordination.
Volume: 9
Issue: 410
Pages: ra6
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Publication
23618652 | J:201114
 
First Author: Liebmann M
Year: 2013
Journal: Neurosci Lett
Title: Astrocytic Cx43 and Cx30 differentially modulate adult neurogenesis in mice.
Volume: 545
Pages: 40-5
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Publication
32046059 | J:302403
 
First Author: Katoozi S
Year: 2020
Journal: Cells
Title: Uncoupling of the Astrocyte Syncytium Differentially Affects AQP4 Isoforms.
Volume: 9
Issue: 2
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Publication
19056987 | J:142034
First Author: Rouach N
Year: 2008
Journal: Science
Title: Astroglial metabolic networks sustain hippocampal synaptic transmission.
Volume: 322
Issue: 5907
Pages: 1551-5
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Publication
22472609 | J:315134
First Author: Ezan P
Year: 2012
Journal: J Cereb Blood Flow Metab
Title: Deletion of astroglial connexins weakens the blood-brain barrier.
Volume: 32
Issue: 8
Pages: 1457-67
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Publication
34210880 | J:323811
First Author: Ribot J
Year: 2021
Journal: Science
Title: Astrocytes close the mouse critical period for visual plasticity.
Volume: 373
Issue: 6550
Pages: 77-81
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Publication
18199768 | J:149339
First Author: Lin JH
Year: 2008
Journal: J Neurosci
Title: A central role of connexin 43 in hypoxic preconditioning.
Volume: 28
Issue: 3
Pages: 681-95
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Publication
26586821 | J:227846
First Author: Roux L
Year: 2015
Journal: J Neurosci
Title: Astroglial Connexin 43 Hemichannels Modulate Olfactory Bulb Slow Oscillations.
Volume: 35
Issue: 46
Pages: 15339-52
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Publication
38722742 | J:349796
First Author: Dossi E
Year: 2024
Journal: Cell Rep
Title: Astroglial gap junctions strengthen hippocampal network activity by sustaining afterhyperpolarization via KCNQ channels.
Volume: 43
Issue: 5
Pages: 114158
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Publication
16707796 | J:108703
First Author: Wallraff A
Year: 2006
Journal: J Neurosci
Title: The impact of astrocytic gap junctional coupling on potassium buffering in the hippocampus.
Volume: 26
Issue: 20
Pages: 5438-47
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Publication
30337521 | J:267577
First Author: Deemyad T
Year: 2018
Journal: Nat Commun
Title: Astrocytes integrate and drive action potential firing in inhibitory subnetworks.
Volume: 9
Issue: 1
Pages: 4336
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Publication
21997206 | J:180069
First Author: Roux L
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Plasticity of astroglial networks in olfactory glomeruli.
Volume: 108
Issue: 45
Pages: 18442-6
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Publication
21536893 | J:171910
First Author: Pannasch U
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Astroglial networks scale synaptic activity and plasticity.
Volume: 108
Issue: 20
Pages: 8467-72
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Publication
30534054 | J:310593
 
First Author: Recabal A
Year: 2018
Journal: Front Cell Neurosci
Title: Connexin-43 Gap Junctions Are Responsible for the Hypothalamic Tanycyte-Coupled Network.
Volume: 12
Pages: 406
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Publication
19535586 | J:150123
First Author: Lutz SE
Year: 2009
Journal: J Neurosci
Title: Deletion of astrocyte connexins 43 and 30 leads to a dysmyelinating phenotype and hippocampal CA1 vacuolation.
Volume: 29
Issue: 24
Pages: 7743-52
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Publication
24081156 | J:217962
First Author: Sibille J
Year: 2014
Journal: J Physiol
Title: Astroglial potassium clearance contributes to short-term plasticity of synaptically evoked currents at the tripartite synapse.
Volume: 592
Issue: 1
Pages: 87-102
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Publication
38996064 | J:353430
First Author: Visser J
Year: 2024
Journal: Cell Rep
Title: Astroglial networks control visual responses of superior collicular neurons and sensory-motor behavior.
Volume: 43
Issue: 7
Pages: 114504
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Publication
32553574 | J:294230
 
First Author: Kuang Y
Year: 2020
Journal: EBioMedicine
Title: A potent antagonist antibody targeting connexin hemichannels alleviates Clouston syndrome symptoms in mutant mice.
Volume: 57
Pages: 102825
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Publication
21264956 | J:167824
First Author: Gosejacob D
Year: 2011
Journal: Glia
Title: Role of astroglial connexin30 in hippocampal gap junction coupling.
Volume: 59
Issue: 3
Pages: 511-9
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Publication
35263595 | J:324830
First Author: Hösli L
Year: 2022
Journal: Cell Rep
Title: Decoupling astrocytes in adult mice impairs synaptic plasticity and spatial learning.
Volume: 38
Issue: 10
Pages: 110484
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Publication
23637189 | J:197146
First Author: May D
Year: 2013
Journal: J Neurosci
Title: Connexin47 protein phosphorylation and stability in oligodendrocytes depend on expression of Connexin43 protein in astrocytes.
Volume: 33
Issue: 18
Pages: 7985-96
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Publication
28689039 | J:275453
 
First Author: Zhang J
Year: 2018
Journal: Brain Res Bull
Title: Connexin43, but not connexin30, contributes to adult neurogenesis in the dentate gyrus.
Volume: 136
Pages: 91-100
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Publication
24349371 | J:211152
First Author: Zhang J
Year: 2013
Journal: PLoS One
Title: Germ-line recombination activity of the widely used hGFAP-Cre and nestin-Cre transgenes.
Volume: 8
Issue: 12
Pages: e82818
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Publication
25037920 | J:235636
First Author: Griemsmann S
Year: 2015
Journal: Cereb Cortex
Title: Characterization of Panglial Gap Junction Networks in the Thalamus, Neocortex, and Hippocampus Reveals a Unique Population of Glial Cells.
Volume: 25
Issue: 10
Pages: 3420-33
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Publication
18942753 | J:156217
First Author: Requardt RP
Year: 2009
Journal: Glia
Title: Quality control of astrocyte-directed Cre transgenic mice: the benefits of a direct link between loss of gene expression and reporter activation.
Volume: 57
Issue: 6
Pages: 680-92
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Publication
22275221 | J:260273
First Author: Torres A
Year: 2012
Journal: Sci Signal
Title: Extracellular Ca²⁺ acts as a mediator of communication from neurons to glia.
Volume: 5
Issue: 208
Pages: ra8
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Publication
28138563 | J:258504
First Author: Xie AX
Year: 2017
Journal: JCI Insight
Title: Ganglionic GFAP + glial Gq-GPCR signaling enhances heart functions in vivo.
Volume: 2
Issue: 2
Pages: e90565
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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