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Search results 801 to 900 out of 3463 for Grasp

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Categories

Hits by Pathway

Hits by Category

Type Details Score
Genotype
Genotype
Symbol: Decr2/Decr2
Background: C57BL/6N-Decr2/Ieg
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dmgdh/Dmgdh
Background: C57BL/6N-Dmgdh/Wtsi
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dmwd/Dmwd
Background: C57BL/6NJ-Dmwd/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dpf1/Dpf1
Background: C57BL/6N-Dpf1/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ell2/Ell2
Background: C57BL/6N-Ell2/Wtsi
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Emilin2/Emilin2
Background: C57BL/6NJ-Emilin2/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: F10/F10<+>
Background: C57BL/6N-F10/H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fars2/Fars2<+>
Background: C57BL/6NJ-Fars2/Mmjax
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fam222a/Fam222a
Background: C57BL/6NJ-Fam222a/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fdx1/Fdx1<+>
Background: C57BL/6N-Fdx1/Ieg
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gjd4/Gjd4
Background: C57BL/6N-Gjd4/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gmnc/Gmnc<+>
Background: C57BL/6N-Gmnc/Wtsi
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gng12/Gng12
Background: C57BL/6NJ-Gng12/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gpr153/Gpr153
Background: C57BL/6NJ-Gpr153/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gyg1/Gyg1<+>
Background: C57BL/6N-Gyg1/Bay
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hhipl1/Hhipl1
Background: C57BL/6N-Hhipl1/H
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igf2bp3/Igf2bp3
Background: C57BL/6NJ-Igf2bp3/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Iqch/Iqch
Background: C57BL/6NJ-Iqch/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Krt25/Krt25
Background: C57BL/6NJ-Krt25/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Krt2/Krt2<+>
Background: C57BL/6N-Krt2/Ucd
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lurap1/Lurap1
Background: C57BL/6NJ-Lurap1/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ltbp4/Ltbp4
Background: C57BL/6NCrl-Ltbp4/Tcp
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mthfd2/Mthfd2<+>
Background: C57BL/6N-Mthfd2/Bay
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Myo1g/Myo1g
Background: C57BL/6NCrl-Myo1g/Ccpcz
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nkiras1/Nkiras1
Background: C57BL/6NCrl-Nkiras1/Ccpcz
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nkpd1/Nkpd1
Background: C57BL/6NJ-Nkpd1/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Npr2/Npr2<+>
Background: C57BL/6N-Npr2/H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Notch1/Notch1<+>
Background: C57BL/6N-Notch1/H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nrbp1/Nrbp1<+>
Background: C57BL/6N-Nrbp1/Wtsi
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Oaz2/Oaz2
Background: C57BL/6NJ-Oaz2/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Otub1/Otub1<+>
Background: C57BL/6N-Otub1/H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Palmd/Palmd
Background: C57BL/6NJ-Palmd/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pkmyt1/Pkmyt1<+>
Background: C57BL/6NJ-Pkmyt1/Mmjax
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pip5k1c/Pip5k1c<+>
Background: C57BL/6N-Pip5k1c/J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rab3gap1/Rab3gap1
Background: C57BL/6NJ-Rab3gap1/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rhbdf1/Rhbdf1<+>
Background: C57BL/6N-Rhbdf1/J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rwdd3/Rwdd3<+>
Background: C57BL/6N-Rwdd3/Ics
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sec61a2/Sec61a2
Background: C57BL/6NJ-Sec61a2/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sel1l3/Sel1l3
Background: C57BL/6NJ-Sel1l3/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sfxn1/Sfxn1
Background: C57BL/6N-Sfxn1/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Slc24a3/Slc24a3
Background: C57BL/6NTac-Slc24a3/Kmpc
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Slc17a2/Slc17a2
Background: C57BL/6NJ-Slc17a2/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Slc22a17/Slc22a17<+>
Background: C57BL/6N-Slc22a17/H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Slc25a46/Slc25a46<+>
Background: C57BL/6NJ-Slc25a46/J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Slc25a24/Slc25a24
Background: C57BL/6N-Slc25a24/Bay
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Slc39a10/Slc39a10<+>
Background: C57BL/6NJ-Slc39a10/Mmjax
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smarcd3/Smarcd3<+>
Background: C57BL/6NJ-Smarcd3/J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Slc6a7/Slc6a7
Background: C57BL/6NJ-Slc6a7/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Slc9a5/Slc9a5
Background: C57BL/6NJ-Slc9a5/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Snx3/Snx3<+>
Background: C57BL/6N-Snx3/J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Snx12/Snx12
Background: C57BL/6NJ-Snx12/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Snx14/Snx14<+>
Background: C57BL/6NTac-Snx14/H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Spata7/Spata7
Background: C57BL/6N-Spata7/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Spats2/Spats2
Background: C57BL/6NJ-Spats2/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Spr/Spr<+>
Background: C57BL/6N-Spr/H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sprr1a/Sprr1a
Background: C57BL/6NJ-Sprr1a/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: St6galnac3/St6galnac3
Background: C57BL/6NJ-St6galnac3/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Srsf6/Srsf6<+>
Background: C57BL/6NJ-Srsf6/Mmjax
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Syt8/Syt8
Background: C57BL/6NJ-Syt8/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tafa1/Tafa1
Background: C57BL/6N-Tafa1/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tbcel/Tbcel
Background: C57BL/6NJ-Tbcel/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Syk/Syk<+>
Background: C57BL/6N-Syk/Ieg
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tango2/Tango2
Background: C57BL/6N-Tango2/BayMmucd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tex29/Tex29
Background: C57BL/6N-Tex29/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tedc2/Tedc2<+>
Background: C57BL/6NJ-Tedc2/Mmjax
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Thap1/Thap1<+>
Background: C57BL/6NJ-Thap1/Mmjax
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tmem131/Tmem131<+>
Background: C57BL/6NJ-Tmem131/Mmjax
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tmem17/Tmem17<+>
Background: C57BL/6NTac-Tmem17/Kmpc
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tmem45a/Tmem45a
Background: C57BL/6N-Tmem45a/MbpMmucd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tmem50b/Tmem50b
Background: C57BL/6N-Tmem50b/Ics
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tnks2/Tnks2
Background: C57BL/6N-Tnks2/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Trmt10b/Trmt10b
Background: C57BL/6NJ-Trmt10b/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tspan9/Tspan9
Background: C57BL/6NJ-Tspan9/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Zdhhc22/Zdhhc22
Background: C57BL/6NJ-Zdhhc22/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Zfp871/Zfp871<+>
Background: C57BL/6N-Zfp871/Bay
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Znhit1/Znhit1<+>
Background: C57BL/6NJ-Znhit1/Mmjax
Zygosity: ht
Has Mutant Allele: true
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Publication
9416615 | -
First Author: Galperin MY
Year: 1997
Journal: Protein Sci
Title: A diverse superfamily of enzymes with ATP-dependent carboxylate-amine/thiol ligase activity.
Volume: 6
Issue: 12
Pages: 2639-43
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Publication
22985965 | -
First Author: Quitterer F
Year: 2012
Journal: J Mol Biol
Title: Biosynthesis of the 22nd genetically encoded amino acid pyrrolysine: structure and reaction mechanism of PylC at 1.5Å resolution.
Volume: 424
Issue: 5
Pages: 270-82
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Protein Domain
IPR003806 | ATP-grasp_PylC-type
Type: Domain
Description: The ATP-grasp fold is one of several distinct ATP-binding folds, and is found in enzymes that catalyze the formation of amide bonds, catalyzing the ATP-dependent ligation of a carboxylate-containing molecule to an amino or thiol group-containing molecule []. This fold is found in many differentenzyme families, including various peptide synthetases, biotin carboxylase, synapsin, succinyl-CoA synthetase, pyruvate phosphate dikinase, and glutathione synthetase, amongst others []. These enzymes contribute predominantly to macromolecular synthesis, using ATP-hydrolysis to activate their substrates. The ATP-grasp fold shares functional and structural similarities with the PIPK (phosphatidylinositol phosphate kinase) and protein kinase superfamilies. The ATP-grasp domain consists of two subdomains with different alpha+beta folds, which grasp the ATP molecule between them. Each subdomain provides a variable loop that forms part of the active site, with regions from other domains also contributing to the active site, even though these other domains are not conserved between the various ATP-grasp enzymes [].This entry describes a type of ATP-grasp fold such as that found in pyrrolysine biosynthesis protein PylC [].
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Protein Domain
IPR013815 | ATP_grasp_subdomain_1
Type: Homologous_superfamily
Description: The ATP-grasp fold is one of several distinct ATP-binding folds, and is found in enzymes that catalyse the formation of amide bonds, catalysing the ATP-dependent ligation of a carboxylate-containing molecule to an amino or thiol group-containing molecule []. This fold is found in many different enzyme families, including various peptide synthetases, biotin carboxylase, synapsin, succinyl-CoA synthetase, pyruvate phosphate dikinase, and glutathione synthetase, amongst others []. These enzymes contribute predominantly to macromolecular synthesis, using ATP-hydrolysis to activate their substrates. The ATP-grasp fold shares functional and structural similarities with the PIPK (phosphatidylinositol phosphate kinase) and protein kinase superfamilies. The ATP-grasp domain consists of two subdomains with different alpha+beta folds, which grasp the ATP molecule between them. Each subdomain provides a variable loop that forms part of the active site, with regions from other domains also contributing to the active site, even though these other domains are not conserved between the various ATP-grasp enzymes [].This entry represents subdomain 1 found at the N-terminal end of the ATP-grasp domain.
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Protein Coding Gene
MGI:96669 | Kcnc3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1352502 | Limd1
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Adamtsl4<em1(IMPC)J> | MGI:5795948
Name: ADAMTS-like 4; endonuclease-mediated mutation 1, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Ky<em1(IMPC)J> | MGI:6407422
Name: kyphoscoliosis peptidase; endonuclease-mediated mutation 1, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Ky/Ky
Background: C57BL/6NJ-Ky/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Slc30a4/Slc30a4
Background: C57BL/6NCrl-Slc30a4/Tcp
Zygosity: hm
Has Mutant Allele: true
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Protein Coding Gene
MGI:1929721 | Rrs1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2654470 | Ctdsp1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1918962 | Dram1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2442119 | Papolg
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1096574 | Car4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1353497 | Slc25a10
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1924399 | Pacs2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2388271 | Mylip
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1926225 | Slc22a17
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2445217 | Xpnpep3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:3702087 | Rnaset2b
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:3587728 | Acsbg2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2389136 | Emilin2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2442663 | Hectd2
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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Cambridge CB2 3EH, United Kingdom