| Type |
Details |
Score |
| Publication |
| First Author: |
Okuda H |
| Year: |
2006 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Novel interaction between HMGA1a and StIP1 in murine terminally differentiated retina. |
| Volume: |
33 |
| Issue: |
1 |
| Pages: |
81-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gurish MF |
| Year: |
1994 |
| Journal: |
Mamm Genome |
| Title: |
Location of the mouse mast cell protease 7 gene (Mcpt7) to chromosome 17. |
| Volume: |
5 |
| Issue: |
10 |
| Pages: |
656-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Himes SR |
| Year: |
1996 |
| Journal: |
Immunity |
| Title: |
High mobility group protein I(Y) is required for function and for c-Rel binding to CD28 response elements within the GM-CSF and IL-2 promoters. |
| Volume: |
5 |
| Issue: |
5 |
| Pages: |
479-89 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lanahan A |
| Year: |
1992 |
| Journal: |
Mol Cell Biol |
| Title: |
Growth factor-induced delayed early response genes. |
| Volume: |
12 |
| Issue: |
9 |
| Pages: |
3919-29 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nishino J |
| Year: |
2008 |
| Journal: |
Cell |
| Title: |
Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression. |
| Volume: |
135 |
| Issue: |
2 |
| Pages: |
227-39 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Albrecht NE |
| Year: |
2018 |
| Journal: |
Cell Rep |
| Title: |
Rapid and Integrative Discovery of Retina Regulatory Molecules. |
| Volume: |
24 |
| Issue: |
9 |
| Pages: |
2506-2519 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Beckers J |
| Year: |
2005 |
| Journal: |
Int J Cancer |
| Title: |
Identification and validation of novel ERBB2 (HER2, NEU) targets including genes involved in angiogenesis. |
| Volume: |
114 |
| Issue: |
4 |
| Pages: |
590-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Belton A |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
HMGA1 induces intestinal polyposis in transgenic mice and drives tumor progression and stem cell properties in colon cancer cells. |
| Volume: |
7 |
| Issue: |
1 |
| Pages: |
e30034 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bronson RT |
| Year: |
1998 |
| Journal: |
Am J Med Genet |
| Title: |
Neuronal ceroid lipofuscinosis (nclf), a new disorder of the mouse linked to chromosome 9. |
| Volume: |
77 |
| Issue: |
4 |
| Pages: |
289-97 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stevens J |
| Year: |
2010 |
| Journal: |
BMC Dev Biol |
| Title: |
Analysis of the asymmetrically expressed Ablim1 locus reveals existence of a lateral plate Nodal-independent left sided signal and an early, left-right independent role for nodal flow. |
| Volume: |
10 |
|
| Pages: |
54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nishino J |
| Year: |
2013 |
| Journal: |
Elife |
| Title: |
A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties. |
| Volume: |
2 |
|
| Pages: |
e00924 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Singh I |
| Year: |
2014 |
| Journal: |
BMC Biol |
| Title: |
Hmga2 is required for canonical WNT signaling during lung development. |
| Volume: |
12 |
|
| Pages: |
21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McKenzie MG |
| Year: |
2019 |
| Journal: |
Neuron |
| Title: |
Non-canonical Wnt Signaling through Ryk Regulates the Generation of Somatostatin- and Parvalbumin-Expressing Cortical Interneurons. |
| Volume: |
103 |
| Issue: |
5 |
| Pages: |
853-864.e4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu W |
| Year: |
2017 |
| Journal: |
Nat Commun |
| Title: |
BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis. |
| Volume: |
8 |
|
| Pages: |
14182 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pavlinkova G |
| Year: |
2009 |
| Journal: |
BMC Genomics |
| Title: |
Maternal diabetes alters transcriptional programs in the developing embryo. |
| Volume: |
10 |
|
| Pages: |
274 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jiang D |
| Year: |
2020 |
| Journal: |
J Comp Neurol |
| Title: |
Spatiotemporal gene expression patterns reveal molecular relatedness between retinal laminae. |
| Volume: |
528 |
| Issue: |
5 |
| Pages: |
729-755 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Johnson KR |
| Year: |
1994 |
| Journal: |
Mamm Genome |
| Title: |
Identification and genetic mapping of 151 dispersed members of 16 ribosomal protein multigene families in the mouse. |
| Volume: |
5 |
| Issue: |
11 |
| Pages: |
670-87 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Machold R |
| Year: |
2011 |
| Journal: |
Gene Expr Patterns |
| Title: |
Genes expressed in Atoh1 neuronal lineages arising from the r1/isthmus rhombic lip. |
| Volume: |
11 |
| Issue: |
5-6 |
| Pages: |
349-59 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shanghai Model Organisms Center |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lewandowski JP |
| Year: |
2015 |
| Journal: |
Dev Biol |
| Title: |
Spatiotemporal regulation of GLI target genes in the mammalian limb bud. |
| Volume: |
406 |
| Issue: |
1 |
| Pages: |
92-103 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientfic Curators |
| Year: |
2013 |
|
| Title: |
Curated associations of genes in MGI and UniProt sequence records |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hoffman BG |
| Year: |
2008 |
| Journal: |
Genome Biol |
| Title: |
Identification of transcripts with enriched expression in the developing and adult pancreas. |
| Volume: |
9 |
| Issue: |
6 |
| Pages: |
R99 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Blackshaw S |
| Year: |
2004 |
| Journal: |
PLoS Biol |
| Title: |
Genomic analysis of mouse retinal development. |
| Volume: |
2 |
| Issue: |
9 |
| Pages: |
E247 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guo G |
| Year: |
2010 |
| Journal: |
Dev Cell |
| Title: |
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. |
| Volume: |
18 |
| Issue: |
4 |
| Pages: |
675-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dickinson ME |
| Year: |
2016 |
| Journal: |
Nature |
| Title: |
High-throughput discovery of novel developmental phenotypes. |
| Volume: |
537 |
| Issue: |
7621 |
| Pages: |
508-514 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
|
| Title: |
Data Curation Using Mouse Genome Assembly |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GUDMAP Consortium |
| Year: |
2004 |
| Journal: |
www.gudmap.org |
| Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hansen J |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
| Volume: |
100 |
| Issue: |
17 |
| Pages: |
9918-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Friedel RH |
| Year: |
2007 |
| Journal: |
Brief Funct Genomic Proteomic |
| Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
| Volume: |
6 |
| Issue: |
3 |
| Pages: |
180-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gray PA |
| Year: |
2004 |
| Journal: |
Science |
| Title: |
Mouse brain organization revealed through direct genome-scale TF expression analysis. |
| Volume: |
306 |
| Issue: |
5705 |
| Pages: |
2255-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thompson CL |
| Year: |
2014 |
| Journal: |
Neuron |
| Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
| Volume: |
83 |
| Issue: |
2 |
| Pages: |
309-323 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Koscielny G |
| Year: |
2014 |
| Journal: |
Nucleic Acids Res |
| Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
| Volume: |
42 |
| Issue: |
Database issue |
| Pages: |
D802-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
International Knockout Mouse Consortium |
| Year: |
2014 |
| Journal: |
Database Download |
| Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
International Mouse Strain Resource |
| Year: |
2014 |
| Journal: |
Database Download |
| Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
|
| Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
|
| Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
| Year: |
2014 |
| Journal: |
Database Release |
| Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hansen GM |
| Year: |
2008 |
| Journal: |
Genome Res |
| Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
| Volume: |
18 |
| Issue: |
10 |
| Pages: |
1670-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Helmholtz Zentrum Muenchen GmbH |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Magdaleno S |
| Year: |
2006 |
| Journal: |
PLoS Biol |
| Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
| Volume: |
4 |
| Issue: |
4 |
| Pages: |
e86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawai J |
| Year: |
2001 |
| Journal: |
Nature |
| Title: |
Functional annotation of a full-length mouse cDNA collection. |
| Volume: |
409 |
| Issue: |
6821 |
| Pages: |
685-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adams DJ |
| Year: |
2024 |
| Journal: |
Nature |
| Title: |
Genetic determinants of micronucleus formation in vivo. |
| Volume: |
627 |
| Issue: |
8002 |
| Pages: |
130-136 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zambrowicz BP |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
| Volume: |
100 |
| Issue: |
24 |
| Pages: |
14109-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
| Journal: |
Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
| Year: |
2004 |
| Journal: |
Database Release |
| Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dey D |
| Year: |
2007 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Fatty acid represses insulin receptor gene expression by impairing HMGA1 through protein kinase Cepsilon. |
| Volume: |
357 |
| Issue: |
2 |
| Pages: |
474-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Arce-Cerezo A |
| Year: |
2015 |
| Journal: |
Sci Rep |
| Title: |
HMGA1 overexpression in adipose tissue impairs adipogenesis and prevents diet-induced obesity and insulin resistance. |
| Volume: |
5 |
|
| Pages: |
14487 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Luo LZ |
| Year: |
2025 |
| Journal: |
J Clin Invest |
| Title: |
HMGA1 acts as an epigenetic gatekeeper of ASCL2 and Wnt signaling during colon tumorigenesis. |
| Volume: |
135 |
| Issue: |
3 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hopper RK |
| Year: |
2016 |
| Journal: |
Circulation |
| Title: |
In Pulmonary Arterial Hypertension, Reduced BMPR2 Promotes Endothelial-to-Mesenchymal Transition via HMGA1 and Its Target Slug. |
| Volume: |
133 |
| Issue: |
18 |
| Pages: |
1783-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhou J |
| Year: |
2015 |
| Journal: |
Cancer Biomark |
| Title: |
Increases urinary HMGA1 in serous epithelial ovarian cancer patients. |
| Volume: |
15 |
| Issue: |
3 |
| Pages: |
325-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu MJ |
| Year: |
2024 |
| Journal: |
Cell Death Dis |
| Title: |
HMGA1 promotes the progression of esophageal squamous cell carcinoma by elevating TKT-mediated upregulation of pentose phosphate pathway. |
| Volume: |
15 |
| Issue: |
7 |
| Pages: |
541 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Veite-Schmahl MJ |
| Year: |
2017 |
| Journal: |
Br J Cancer |
| Title: |
HMGA1 expression levels are elevated in pancreatic intraepithelial neoplasia cells in the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer. |
| Volume: |
117 |
| Issue: |
5 |
| Pages: |
639-647 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huang R |
| Year: |
2015 |
| Journal: |
Mol Cell Biochem |
| Title: |
Overexpression of HMGA1 correlates with the malignant status and prognosis of breast cancer. |
| Volume: |
404 |
| Issue: |
1-2 |
| Pages: |
251-7 |
|
•
•
•
•
•
|
| Allele |
| Name: |
high mobility group AT-hook 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fedele M |
| Year: |
2018 |
| Journal: |
Cancer Res |
| Title: |
Retraction: Haploinsufficiency of the Hmga1 Gene Causes Cardiac Hypertrophy and Myelo-Lymphoproliferative Disorders in Mice. |
| Volume: |
78 |
| Issue: |
24 |
| Pages: |
6908 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shah SN |
| Year: |
2013 |
| Journal: |
PLoS One |
| Title: |
HMGA1: a master regulator of tumor progression in triple-negative breast cancer cells. |
| Volume: |
8 |
| Issue: |
5 |
| Pages: |
e63419 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
This entry represents HMGA1 fromvchordates. Overexpression of HMGA1 correlates with the malignant status and prognosis of cancers [, , ].The high mobility group (HMG) proteins are the most abundant and ubiquitous nonhistone chromosomal proteins. They bind to DNA and to nucleosomes and are involved in the regulation of DNA-dependent processes such as transcription, replication, recombination, and DNA repair. They can be grouped into three families: HMGB (HMG 1/2), HMGN (HMG 14/17) and HMGA (HMG I/Y). The characteristic domains are: AT-hook for the HMGA family, the HMG Box for the HMGB family, and the nucleosome-binding domain (NBD) for the members of the HMGN family []. |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion, Linda MS Resar |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu Y |
| Year: |
2004 |
| Journal: |
Cancer Res |
| Title: |
The HMG-I oncogene causes highly penetrant, aggressive lymphoid malignancy in transgenic mice and is overexpressed in human leukemia. |
| Volume: |
64 |
| Issue: |
10 |
| Pages: |
3371-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tesfaye A |
| Year: |
2007 |
| Journal: |
Cancer Res |
| Title: |
The high-mobility group A1 gene up-regulates cyclooxygenase 2 expression in uterine tumorigenesis. |
| Volume: |
67 |
| Issue: |
9 |
| Pages: |
3998-4004 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(H2-K-Hmga1)#Lmsr/? |
| Background: |
involves: C57BL/6 * SJL |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pierantoni GM |
| Year: |
2002 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
The homeodomain-interacting protein kinase 2 gene is expressed late in embryogenesis and preferentially in retina, muscle, and neural tissues. |
| Volume: |
290 |
| Issue: |
3 |
| Pages: |
942-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hu Q |
| Year: |
2023 |
| Journal: |
EMBO J |
| Title: |
Anti-hsa-miR-59 alleviates premature senescence associated with Hutchinson-Gilford progeria syndrome in mice. |
| Volume: |
42 |
| Issue: |
1 |
| Pages: |
e110937 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fedele M |
| Year: |
2011 |
| Journal: |
Eur J Cancer |
| Title: |
Expression of a truncated Hmga1b gene induces gigantism, lipomatosis and B-cell lymphomas in mice. |
| Volume: |
47 |
| Issue: |
3 |
| Pages: |
470-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dai N |
| Year: |
2017 |
| Journal: |
Elife |
| Title: |
IGF2 mRNA binding protein-2 is a tumor promoter that drives cancer proliferation through its client mRNAs IGF2 and HMGA1. |
| Volume: |
6 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao Y |
| Year: |
2024 |
| Journal: |
Nat Commun |
| Title: |
High mobility group A1 (HMGA1) promotes the tumorigenesis of colorectal cancer by increasing lipid synthesis. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
9909 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
107
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
111
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
107
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dasgupta S |
| Year: |
2011 |
| Journal: |
Biochim Biophys Acta |
| Title: |
Mechanism of lipid induced insulin resistance: activated PKCε is a key regulator. |
| Volume: |
1812 |
| Issue: |
4 |
| Pages: |
495-506 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chiou SH |
| Year: |
2018 |
| Journal: |
Sci Rep |
| Title: |
Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
14008 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Madison BB |
| Year: |
2015 |
| Journal: |
PLoS Genet |
| Title: |
Let-7 Represses Carcinogenesis and a Stem Cell Phenotype in the Intestine via Regulation of Hmga2. |
| Volume: |
11 |
| Issue: |
8 |
| Pages: |
e1005408 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fedele M |
| Year: |
2001 |
| Journal: |
Carcinogenesis |
| Title: |
Role of the high mobility group A proteins in human lipomas. |
| Volume: |
22 |
| Issue: |
10 |
| Pages: |
1583-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Di Marcantonio D |
| Year: |
2015 |
| Journal: |
Exp Cell Res |
| Title: |
PKCε as a novel promoter of skeletal muscle differentiation and regeneration. |
| Volume: |
339 |
| Issue: |
1 |
| Pages: |
10-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fujikane R |
| Year: |
2016 |
| Journal: |
Sci Rep |
| Title: |
Function of high-mobility group A proteins in the DNA damage signaling for the induction of apoptosis. |
| Volume: |
6 |
|
| Pages: |
31714 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Resar L |
| Year: |
2018 |
| Journal: |
Cancer Res |
| Title: |
Lessons from the Crypt: HMGA1-Amping up Wnt for Stem Cells and Tumor Progression. |
| Volume: |
78 |
| Issue: |
8 |
| Pages: |
1890-1897 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Baron RM |
| Year: |
2018 |
| Journal: |
J Leukoc Biol |
| Title: |
Frontline Science: Targeted expression of a dominant-negative high mobility group A1 transgene improves outcome in sepsis. |
| Volume: |
104 |
| Issue: |
4 |
| Pages: |
677-689 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dudka D |
| Year: |
2025 |
| Journal: |
Nature |
| Title: |
Satellite DNA shapes dictate pericentromere packaging in female meiosis. |
| Volume: |
638 |
| Issue: |
8051 |
| Pages: |
814-822 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
González-Romero R |
| Year: |
2015 |
| Journal: |
Mol Biol Evol |
| Title: |
Evolution of high mobility group nucleosome-binding proteins and its implications for vertebrate chromatin specialization. |
| Volume: |
32 |
| Issue: |
1 |
| Pages: |
121-31 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|