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Search results 801 to 851 out of 851 for Hras

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Type Details Score
Genotype
Symbol: Adap1/Adap1 Tg(tetO-HRAS)65Lc/?
Background: involves: C3H * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Nogueira C
Year: 2010
Journal: Oncogene
Title: Cooperative interactions of PTEN deficiency and RAS activation in melanoma metastasis.
Volume: 29
Issue: 47
Pages: 6222-32
Publication
First Author: Yang J
Year: 2010
Journal: J Clin Invest
Title: Conditional ablation of Ikkb inhibits melanoma tumor development in mice.
Volume: 120
Issue: 7
Pages: 2563-74
Publication
First Author: Machida Y
Year: 2021
Journal: Oncol Lett
Title: Different properties of mammary carcinogenesis induced by two chemical carcinogens, DMBA and PhIP, in heterozygous BALB/c Trp53 knockout mice.
Volume: 22
Issue: 4
Pages: 738
Publication
First Author: Mukhopadhyay A
Year: 2011
Journal: J Invest Dermatol
Title: Activated Kras alters epidermal homeostasis of mouse skin, resulting in redundant skin and defective hair cycling.
Volume: 131
Issue: 2
Pages: 311-9
Publication  
First Author: Witherspoon JG
Year: 2024
Journal: Redox Biol
Title: Mutant Nrf2(E79Q) enhances the promotion and progression of a subset of oncogenic Ras keratinocytes and skin tumors.
Volume: 75
Pages: 103261
Publication
First Author: Manenti G
Year: 2008
Journal: Oncogene
Title: Cis-acting genomic elements of the Pas1 locus control Kras mutability in lung tumors.
Volume: 27
Issue: 43
Pages: 5753-8
Publication
First Author: Pazzaglia S
Year: 2002
Journal: Radiat Res
Title: The genetic control of chemically and radiation-induced skin tumorigenesis: a study with carcinogenesis-susceptible and carcinogenesis-resistant mice.
Volume: 158
Issue: 1
Pages: 78-83
Publication
First Author: Walker GJ
Year: 2002
Journal: J Invest Dermatol
Title: Pathways to melanoma development: lessons from the mouse.
Volume: 119
Issue: 4
Pages: 783-92
Publication
First Author: Kemp CJ
Year: 2005
Journal: Semin Cancer Biol
Title: Multistep skin cancer in mice as a model to study the evolution of cancer cells.
Volume: 15
Issue: 6
Pages: 460-73
Publication
First Author: Jackson MA
Year: 2006
Journal: Toxicol Sci
Title: Genetic alterations in cancer knowledge system: analysis of gene mutations in mouse and human liver and lung tumors.
Volume: 90
Issue: 2
Pages: 400-18
Publication
First Author: Su F
Year: 2012
Journal: N Engl J Med
Title: RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors.
Volume: 366
Issue: 3
Pages: 207-15
Publication
First Author: Bu W
Year: 2019
Journal: Cancer Res
Title: Mammary Precancerous Stem and Non-Stem Cells Evolve into Cancers of Distinct Subtypes.
Volume: 79
Issue: 1
Pages: 61-71
Publication
First Author: Goldstein J
Year: 2015
Journal: Mol Biol Cell
Title: Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis.
Volume: 26
Issue: 20
Pages: 3606-14
Strain
Attribute String: mutant strain, congenic, transgenic, spontaneous mutation
Publication
First Author: Muto S
Year: 2007
Journal: Cancer Sci
Title: Decreased c-kit function inhibits enhanced skin carcinogenesis in c-Ha-ras protooncogene transgenic mice.
Volume: 98
Issue: 10
Pages: 1549-56
Strain
Attribute String: mutant strain, congenic, transgenic, spontaneous mutation
Publication  
First Author: Ahmad I
Year: 2011
Journal: Cell Death Dis
Title: Ras mutation cooperates with β-catenin activation to drive bladder tumourigenesis.
Volume: 2
Pages: e124
Publication
First Author: Erickson HL
Year: 2024
Journal: Immunity
Title: Cancer stem cells release interleukin-33 within large oncosomes to promote immunosuppressive differentiation of macrophage precursors.
Volume: 57
Issue: 8
Pages: 1908-1922.e6
Publication
First Author: Storer RD
Year: 2003
Journal: Mutat Res
Title: Transgenic tumor models for carcinogen identification: the heterozygous Trp53-deficient and RasH2 mouse lines.
Volume: 540
Issue: 2
Pages: 165-76
Publication
First Author: Oh WJ
Year: 2007
Journal: Carcinogenesis
Title: Histological and proteomic analysis of reversible H-RasV12G expression in transgenic mouse skin.
Volume: 28
Issue: 10
Pages: 2244-52
Publication
First Author: Kon S
Year: 2017
Journal: Nat Cell Biol
Title: Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes.
Volume: 19
Issue: 5
Pages: 530-541
Publication
First Author: Xia Y
Year: 2022
Journal: Cancer Res
Title: PKM2 Is Essential for Bladder Cancer Growth and Maintenance.
Volume: 82
Issue: 4
Pages: 571-585
Publication  
First Author: Koso H
Year: 2019
Journal: Exp Eye Res
Title: Ras activation in retinal progenitor cells induces tumor formation in the eye.
Volume: 180
Pages: 39-42
Strain
Attribute String: mutant stock, transgenic
Publication      
First Author: Modica TM
Year: 2012
Journal: eThOS
Title: Ph.D. Thesis, Open University: A mouse model to study inducible oncogene cooperation in vivo
Genotype
Symbol: Flt4/Flt4<+> Kras/Kras<+> Tg(HRAS)2Jic/?
Background: involves: 129S/SvEv * BALB/c * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(RasE)290Biat/?
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(Upk2-cre)6Xrw/? Tg(Upk2-HRAS*Q61L)5Xrw/?
Background: involves: 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Cleary AS
Year: 2014
Journal: Nature
Title: Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers.
Volume: 508
Issue: 7494
Pages: 113-7
Publication
First Author: Kopasz AG
Year: 2022
Journal: BMC Biol
Title: A versatile transposon-based technology to generate loss- and gain-of-function phenotypes in the mouse liver.
Volume: 20
Issue: 1
Pages: 74
Publication
First Author: Ferreira-Gonzalez A
Year: 1995
Journal: Carcinogenesis
Title: Ras oncogene activation during hepatocarcinogenesis in B6C3F1 male mice by dichloroacetic and trichloroacetic acids.
Volume: 16
Issue: 3
Pages: 495-500
Publication
First Author: Hacker E
Year: 2008
Journal: Int J Cancer
Title: Reduced expression of IL-18 is a marker of ultraviolet radiation-induced melanomas.
Volume: 123
Issue: 1
Pages: 227-31
Publication
First Author: Yang Z
Year: 2017
Journal: PLoS One
Title: Genomic sequencing identifies a few mutations driving the independent origin of primary liver tumors in a chronic hepatitis murine model.
Volume: 12
Issue: 11
Pages: e0187551
Publication
First Author: Ter Braak B
Year: 2017
Journal: Breast Cancer Res
Title: Insulin-like growth factor 1 receptor activation promotes mammary gland tumor development by increasing glycolysis and promoting biomass production.
Volume: 19
Issue: 1
Pages: 14
Publication
First Author: Musteanu M
Year: 2012
Journal: Nat Methods
Title: A mouse model to identify cooperating signaling pathways in cancer.
Volume: 9
Issue: 9
Pages: 897-900
Publication
First Author: Plichta KA
Year: 2012
Journal: Cancer Res
Title: Basal but not luminal mammary epithelial cells require PI3K/mTOR signaling for Ras-driven overgrowth.
Volume: 72
Issue: 22
Pages: 5856-66
Publication
First Author: Akter E
Year: 2022
Journal: Cell Rep
Title: Non-degradable autophagic vacuoles are indispensable for cell competition.
Volume: 40
Issue: 9
Pages: 111292
Publication
First Author: Gilbert E
Year: 1997
Journal: Int J Cancer
Title: In vivo effects of activated H-ras oncogene expressed in the liver and in urogenital tissues.
Volume: 73
Issue: 5
Pages: 749-56
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pten/Pten Tg(RasE)290Biat/?
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Hortal AM
Year: 2022
Journal: Mol Cancer
Title: Overexpression of wild type RRAS2, without oncogenic mutations, drives chronic lymphocytic leukemia.
Volume: 21
Issue: 1
Pages: 35
Publication
First Author: Kelley MB
Year: 2022
Journal: PLoS One
Title: Loss of Tpl2 activates compensatory signaling and resistance to EGFR/MET dual inhibition in v-RAS transduced keratinocytes.
Volume: 17
Issue: 3
Pages: e0266017
Publication
First Author: Qu X
Year: 2012
Journal: Development
Title: Glycosaminoglycan-dependent restriction of FGF diffusion is necessary for lacrimal gland development.
Volume: 139
Issue: 15
Pages: 2730-9
Publication  
First Author: Van Duzer A
Year: 2019
Journal: Life Sci Alliance
Title: ADAP1 promotes invasive squamous cell carcinoma progression and predicts patient survival.
Volume: 2
Issue: 6
Publication
First Author: Vizoso M
Year: 2022
Journal: Nat Commun
Title: A doxycycline- and light-inducible Cre recombinase mouse model for optogenetic genome editing.
Volume: 13
Issue: 1
Pages: 6442
Publication
First Author: Tilli MT
Year: 2003
Journal: Breast Cancer Res
Title: Conditional mouse models demonstrate oncogene-dependent differences in tumor maintenance and recurrence.
Volume: 5
Issue: 4
Pages: 202-5
Publication
First Author: van der Weyden L
Year: 2013
Journal: J Pathol
Title: Cancer of mice and men: old twists and new tails.
Volume: 230
Issue: 1
Pages: 4-16
Publication
First Author: Kobayashi T
Year: 2015
Journal: Nat Rev Cancer
Title: Modelling bladder cancer in mice: opportunities and challenges.
Volume: 15
Issue: 1
Pages: 42-54
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112