| Type |
Details |
Score |
| Publication |
| First Author: |
Lüthi AU |
| Year: |
2009 |
| Journal: |
Immunity |
| Title: |
Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases. |
| Volume: |
31 |
| Issue: |
1 |
| Pages: |
84-98 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Silveira TN |
| Year: |
2010 |
| Journal: |
Infect Immun |
| Title: |
Pore formation triggered by Legionella spp. is an Nlrc4 inflammasome-dependent host cell response that precedes pyroptosis. |
| Volume: |
78 |
| Issue: |
3 |
| Pages: |
1403-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Samelko L |
| Year: |
2021 |
| Journal: |
PLoS One |
| Title: |
Metal-induced delayed type hypersensitivity responses potentiate particle induced osteolysis in a sex and age dependent manner. |
| Volume: |
16 |
| Issue: |
5 |
| Pages: |
e0251885 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sun Q |
| Year: |
2013 |
| Journal: |
J Biol Chem |
| Title: |
Caspase 1 activation is protective against hepatocyte cell death by up-regulating beclin 1 protein and mitochondrial autophagy in the setting of redox stress. |
| Volume: |
288 |
| Issue: |
22 |
| Pages: |
15947-58 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thompson JK |
| Year: |
2017 |
| Journal: |
Am J Pathol |
| Title: |
Asbestos-Induced Mesothelial to Fibroblastic Transition Is Modulated by the Inflammasome. |
| Volume: |
187 |
| Issue: |
3 |
| Pages: |
665-678 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang B |
| Year: |
2002 |
| Journal: |
J Immunol |
| Title: |
Contribution of Langerhans cell-derived IL-18 to contact hypersensitivity. |
| Volume: |
168 |
| Issue: |
7 |
| Pages: |
3303-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zaki MH |
| Year: |
2010 |
| Journal: |
Immunity |
| Title: |
The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. |
| Volume: |
32 |
| Issue: |
3 |
| Pages: |
379-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pereira MS |
| Year: |
2011 |
| Journal: |
J Immunol |
| Title: |
Activation of NLRC4 by flagellated bacteria triggers caspase-1-dependent and -independent responses to restrict Legionella pneumophila replication in macrophages and in vivo. |
| Volume: |
187 |
| Issue: |
12 |
| Pages: |
6447-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawaguchi M |
| Year: |
2011 |
| Journal: |
Circulation |
| Title: |
Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury. |
| Volume: |
123 |
| Issue: |
6 |
| Pages: |
594-604 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu D |
| Year: |
2017 |
| Journal: |
Arterioscler Thromb Vasc Biol |
| Title: |
NLRP3 (Nucleotide Oligomerization Domain-Like Receptor Family, Pyrin Domain Containing 3)-Caspase-1 Inflammasome Degrades Contractile Proteins: Implications for Aortic Biomechanical Dysfunction and Aneurysm and Dissection Formation. |
| Volume: |
37 |
| Issue: |
4 |
| Pages: |
694-706 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gasparoto TH |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
Inflammasome activation is critical to the protective immune response during chemically induced squamous cell carcinoma. |
| Volume: |
9 |
| Issue: |
9 |
| Pages: |
e107170 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mencacci A |
| Year: |
2000 |
| Journal: |
Infect Immun |
| Title: |
Interleukin 18 restores defective Th1 immunity to Candida albicans in caspase 1-deficient mice. |
| Volume: |
68 |
| Issue: |
9 |
| Pages: |
5126-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Melnikov VY |
| Year: |
2001 |
| Journal: |
J Clin Invest |
| Title: |
Impaired IL-18 processing protects caspase-1-deficient mice from ischemic acute renal failure. |
| Volume: |
107 |
| Issue: |
9 |
| Pages: |
1145-52 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lai MA |
| Year: |
2013 |
| Journal: |
PLoS One |
| Title: |
Innate immune detection of flagellin positively and negatively regulates salmonella infection. |
| Volume: |
8 |
| Issue: |
8 |
| Pages: |
e72047 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ercan I |
| Year: |
2023 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Bilirubin induces microglial NLRP3 inflammasome activation in vitro and in vivo. |
| Volume: |
125 |
|
| Pages: |
103850 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stienstra R |
| Year: |
2011 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Inflammasome is a central player in the induction of obesity and insulin resistance. |
| Volume: |
108 |
| Issue: |
37 |
| Pages: |
15324-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schnare M |
| Year: |
2001 |
| Journal: |
Nat Immunol |
| Title: |
Toll-like receptors control activation of adaptive immune responses. |
| Volume: |
2 |
| Issue: |
10 |
| Pages: |
947-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ioannou GN |
| Year: |
2023 |
| Journal: |
J Lipid Res |
| Title: |
Genetic deletion or pharmacologic inhibition of the Nlrp3 inflammasome did not ameliorate experimental NASH. |
| Volume: |
64 |
| Issue: |
2 |
| Pages: |
100330 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Licandro G |
| Year: |
2013 |
| Journal: |
Eur J Immunol |
| Title: |
The NLRP3 inflammasome affects DNA damage responses after oxidative and genotoxic stress in dendritic cells. |
| Volume: |
43 |
| Issue: |
8 |
| Pages: |
2126-37 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thapa A |
| Year: |
2021 |
| Journal: |
Leukemia |
| Title: |
Danger-associated molecular pattern molecules take unexpectedly a central stage in Nlrp3 inflammasome-caspase-1-mediated trafficking of hematopoietic stem/progenitor cells. |
| Volume: |
35 |
| Issue: |
9 |
| Pages: |
2658-2671 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suresh R |
| Year: |
2016 |
| Journal: |
J Cell Sci |
| Title: |
Complement-mediated 'bystander' damage initiates host NLRP3 inflammasome activation. |
| Volume: |
129 |
| Issue: |
9 |
| Pages: |
1928-39 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhuang Y |
| Year: |
2015 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
Albumin impairs renal tubular tight junctions via targeting the NLRP3 inflammasome. |
| Volume: |
308 |
| Issue: |
9 |
| Pages: |
F1012-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Weinheimer-Haus EM |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
Nod-like receptor protein-3 inflammasome plays an important role during early stages of wound healing. |
| Volume: |
10 |
| Issue: |
3 |
| Pages: |
e0119106 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee HE |
| Year: |
2019 |
| Journal: |
Sci Rep |
| Title: |
Inhibition of NLRP3 inflammasome in tumor microenvironment leads to suppression of metastatic potential of cancer cells. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
12277 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gelfand BD |
| Year: |
2015 |
| Journal: |
Cell Rep |
| Title: |
Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome. |
| Volume: |
11 |
| Issue: |
11 |
| Pages: |
1686-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Duhalde Vega M |
| Year: |
2022 |
| Journal: |
Sci Adv |
| Title: |
PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease. |
| Volume: |
8 |
| Issue: |
38 |
| Pages: |
eabn6545 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ma H |
| Year: |
2021 |
| Journal: |
Front Immunol |
| Title: |
NLRP3 Inflammasome Contributes to Host Defense Against Talaromyces marneffei Infection. |
| Volume: |
12 |
|
| Pages: |
760095 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen KW |
| Year: |
2016 |
| Journal: |
Eur J Immunol |
| Title: |
The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonists. |
| Volume: |
46 |
| Issue: |
4 |
| Pages: |
1004-10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Deng Q |
| Year: |
2019 |
| Journal: |
Cancer Lett |
| Title: |
NLRP3 inflammasomes in macrophages drive colorectal cancer metastasis to the liver. |
| Volume: |
442 |
|
| Pages: |
21-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Alam MA |
| Year: |
2023 |
| Journal: |
Int J Mol Sci |
| Title: |
Deficiency of Caspase-1 Attenuates HIV-1-Associated Atherogenesis in Mice. |
| Volume: |
24 |
| Issue: |
16 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Patankar YR |
| Year: |
2013 |
| Journal: |
Infect Immun |
| Title: |
Flagellar motility is a key determinant of the magnitude of the inflammasome response to Pseudomonas aeruginosa. |
| Volume: |
81 |
| Issue: |
6 |
| Pages: |
2043-52 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Toldo S |
| Year: |
2015 |
| Journal: |
Cardiovasc Res |
| Title: |
Independent roles of the priming and the triggering of the NLRP3 inflammasome in the heart. |
| Volume: |
105 |
| Issue: |
2 |
| Pages: |
203-12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chalkiadaki A |
| Year: |
2012 |
| Journal: |
Cell Metab |
| Title: |
High-fat diet triggers inflammation-induced cleavage of SIRT1 in adipose tissue to promote metabolic dysfunction. |
| Volume: |
16 |
| Issue: |
2 |
| Pages: |
180-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Skotte NH |
| Year: |
2020 |
| Journal: |
Exp Neurol |
| Title: |
Compromised IGF signaling causes caspase-6 activation in Huntington disease. |
| Volume: |
332 |
|
| Pages: |
113396 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shahzad K |
| Year: |
2022 |
| Journal: |
Kidney Int |
| Title: |
Podocyte-specific Nlrp3 inflammasome activation promotes diabetic kidney disease. |
| Volume: |
102 |
| Issue: |
4 |
| Pages: |
766-779 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McDaniel MM |
| Year: |
2020 |
| Journal: |
Cell Rep |
| Title: |
Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming. |
| Volume: |
31 |
| Issue: |
5 |
| Pages: |
107604 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bruder-Nascimento T |
| Year: |
2016 |
| Journal: |
Circulation |
| Title: |
NLRP3 Inflammasome Mediates Aldosterone-Induced Vascular Damage. |
| Volume: |
134 |
| Issue: |
23 |
| Pages: |
1866-1880 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li D |
| Year: |
2023 |
| Journal: |
Sci Rep |
| Title: |
ASC- and caspase-1-deficient C57BL/6 mice do not develop demyelinating disease after infection with Theiler's murine encephalomyelitis virus. |
| Volume: |
13 |
| Issue: |
1 |
| Pages: |
10960 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Malik AF |
| Year: |
2011 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Inflammasome components Asc and caspase-1 mediate biomaterial-induced inflammation and foreign body response. |
| Volume: |
108 |
| Issue: |
50 |
| Pages: |
20095-100 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kearns AC |
| Year: |
2019 |
| Journal: |
Arterioscler Thromb Vasc Biol |
| Title: |
Caspase-1 Activation Is Related With HIV-Associated Atherosclerosis in an HIV Transgenic Mouse Model and HIV Patient Cohort. |
| Volume: |
39 |
| Issue: |
9 |
| Pages: |
1762-1775 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Qu W |
| Year: |
2018 |
| Journal: |
Front Immunol |
| Title: |
Triggering Receptors Expressed on Myeloid Cells 2 Promotes Corneal Resistance Against Pseudomonas aeruginosa by Inhibiting Caspase-1-Dependent Pyroptosis. |
| Volume: |
9 |
|
| Pages: |
1121 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu YL |
| Year: |
2017 |
| Journal: |
Oncotarget |
| Title: |
RIP3 deficiency ameliorates inflammatory response in mice infected with influenza H7N9 virus infection. |
| Volume: |
8 |
| Issue: |
17 |
| Pages: |
27715-27724 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li S |
| Year: |
2022 |
| Journal: |
Cell Rep |
| Title: |
Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice. |
| Volume: |
41 |
| Issue: |
4 |
| Pages: |
111532 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bauer R |
| Year: |
2024 |
| Journal: |
Front Immunol |
| Title: |
NLRP3 promotes allergic responses to birch pollen extract in a model of intranasal sensitization. |
| Volume: |
15 |
|
| Pages: |
1393819 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sarkar A |
| Year: |
2006 |
| Journal: |
J Immunol |
| Title: |
ASC directs NF-kappaB activation by regulating receptor interacting protein-2 (RIP2) caspase-1 interactions. |
| Volume: |
176 |
| Issue: |
8 |
| Pages: |
4979-86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Izquierdo M |
| Year: |
1999 |
| Journal: |
EMBO J |
| Title: |
Blocked negative selection of developing T cells in mice expressing the baculovirus p35 caspase inhibitor. |
| Volume: |
18 |
| Issue: |
1 |
| Pages: |
156-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gaucher D |
| Year: |
2003 |
| Journal: |
Gene |
| Title: |
Gerbil interleukin-18 and caspase-1: cloning, expression and characterization. |
| Volume: |
307 |
|
| Pages: |
159-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Santic M |
| Year: |
2007 |
| Journal: |
Infect Immun |
| Title: |
Host-dependent trigger of caspases and apoptosis by Legionella pneumophila. |
| Volume: |
75 |
| Issue: |
6 |
| Pages: |
2903-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hara H |
| Year: |
2008 |
| Journal: |
J Immunol |
| Title: |
Dependency of caspase-1 activation induced in macrophages by Listeria monocytogenes on cytolysin, listeriolysin O, after evasion from phagosome into the cytoplasm. |
| Volume: |
180 |
| Issue: |
12 |
| Pages: |
7859-68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ayna G |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
ATP release from dying autophagic cells and their phagocytosis are crucial for inflammasome activation in macrophages. |
| Volume: |
7 |
| Issue: |
6 |
| Pages: |
e40069 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chiu GS |
| Year: |
2012 |
| Journal: |
J Neurosci |
| Title: |
Hypoxia/reoxygenation impairs memory formation via adenosine-dependent activation of caspase 1. |
| Volume: |
32 |
| Issue: |
40 |
| Pages: |
13945-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Silva GK |
| Year: |
2013 |
| Journal: |
J Immunol |
| Title: |
Apoptosis-associated speck-like protein containing a caspase recruitment domain inflammasomes mediate IL-1β response and host resistance to Trypanosoma cruzi infection. |
| Volume: |
191 |
| Issue: |
6 |
| Pages: |
3373-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li M |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
Broad-spectrum antibiotic or G-CSF as potential countermeasures for impaired control of bacterial infection associated with an SPE exposure during spaceflight. |
| Volume: |
10 |
| Issue: |
3 |
| Pages: |
e0120126 |
|
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•
•
•
•
|
| Publication |
| First Author: |
Hendrikx T |
| Year: |
2015 |
| Journal: |
FEBS J |
| Title: |
Bone marrow-specific caspase-1/11 deficiency inhibits atherosclerosis development in Ldlr(-/-) mice. |
| Volume: |
282 |
| Issue: |
12 |
| Pages: |
2327-38 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cavailles P |
| Year: |
2014 |
| Journal: |
PLoS Pathog |
| Title: |
A highly conserved Toxo1 haplotype directs resistance to toxoplasmosis and its associated caspase-1 dependent killing of parasite and host macrophage. |
| Volume: |
10 |
| Issue: |
4 |
| Pages: |
e1004005 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Conos SA |
| Year: |
2016 |
| Journal: |
Cell Death Differ |
| Title: |
Cell death is not essential for caspase-1-mediated interleukin-1β activation and secretion. |
| Volume: |
23 |
| Issue: |
11 |
| Pages: |
1827-1838 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rocha FRG |
| Year: |
2020 |
| Journal: |
Sci Rep |
| Title: |
Relevance of Caspase-1 and Nlrp3 Inflammasome on Inflammatory Bone Resorption in A Murine Model of Periodontitis. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
7823 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zheng Y |
| Year: |
2018 |
| Journal: |
EMBO J |
| Title: |
Zika virus elicits inflammation to evade antiviral response by cleaving cGAS via NS1-caspase-1 axis. |
| Volume: |
37 |
| Issue: |
18 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Aries A |
| Year: |
2014 |
| Journal: |
Cell Death Dis |
| Title: |
Caspase-1 cleavage of transcription factor GATA4 and regulation of cardiac cell fate. |
| Volume: |
5 |
|
| Pages: |
e1566 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
156
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
183
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
178
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
178
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
155
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
159
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
183
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
159
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
162
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
410
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
410
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
183
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
280
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang Y |
| Year: |
2017 |
| Journal: |
Immunity |
| Title: |
Inflammasome Activation Triggers Caspase-1-Mediated Cleavage of cGAS to Regulate Responses to DNA Virus Infection. |
| Volume: |
46 |
| Issue: |
3 |
| Pages: |
393-404 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Roberts TL |
| Year: |
2009 |
| Journal: |
Science |
| Title: |
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. |
| Volume: |
323 |
| Issue: |
5917 |
| Pages: |
1057-60 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fernandes-Alnemri T |
| Year: |
2010 |
| Journal: |
Nat Immunol |
| Title: |
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. |
| Volume: |
11 |
| Issue: |
5 |
| Pages: |
385-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang K |
| Year: |
2020 |
| Journal: |
Cell |
| Title: |
Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis. |
| Volume: |
180 |
| Issue: |
5 |
| Pages: |
941-955.e20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Heilig R |
| Year: |
2018 |
| Journal: |
Eur J Immunol |
| Title: |
The Gasdermin-D pore acts as a conduit for IL-1β secretion in mice. |
| Volume: |
48 |
| Issue: |
4 |
| Pages: |
584-592 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Qu Y |
| Year: |
2012 |
| Journal: |
Nature |
| Title: |
Phosphorylation of NLRC4 is critical for inflammasome activation. |
| Volume: |
490 |
| Issue: |
7421 |
| Pages: |
539-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang L |
| Year: |
2015 |
| Journal: |
Science |
| Title: |
Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization. |
| Volume: |
350 |
| Issue: |
6259 |
| Pages: |
404-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dela Cruz CS |
| Year: |
2012 |
| Journal: |
Cell Host Microbe |
| Title: |
Chitinase 3-like-1 promotes Streptococcus pneumoniae killing and augments host tolerance to lung antibacterial responses. |
| Volume: |
12 |
| Issue: |
1 |
| Pages: |
34-46 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okondo MC |
| Year: |
2018 |
| Journal: |
Cell Chem Biol |
| Title: |
Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome. |
| Volume: |
25 |
| Issue: |
3 |
| Pages: |
262-267.e5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wolf AJ |
| Year: |
2016 |
| Journal: |
Cell |
| Title: |
Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan. |
| Volume: |
166 |
| Issue: |
3 |
| Pages: |
624-636 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sutterwala FS |
| Year: |
2006 |
| Journal: |
Immunity |
| Title: |
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. |
| Volume: |
24 |
| Issue: |
3 |
| Pages: |
317-27 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ewald SE |
| Year: |
2014 |
| Journal: |
Infect Immun |
| Title: |
NLRP1 is an inflammasome sensor for Toxoplasma gondii. |
| Volume: |
82 |
| Issue: |
1 |
| Pages: |
460-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Van Opdenbosch N |
| Year: |
2014 |
| Journal: |
Nat Commun |
| Title: |
Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation. |
| Volume: |
5 |
|
| Pages: |
3209 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hasgur S |
| Year: |
2022 |
| Journal: |
Am J Transplant |
| Title: |
Macrophage-inducible C-type lectin activates B cells to promote T cell reconstitution in heart allograft recipients. |
| Volume: |
22 |
| Issue: |
7 |
| Pages: |
1779-1790 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Swenson-Fields KI |
| Year: |
2022 |
| Journal: |
Front Mol Biosci |
| Title: |
Caspase-1 and the inflammasome promote polycystic kidney disease progression. |
| Volume: |
9 |
|
| Pages: |
971219 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Karunakaran D |
| Year: |
2016 |
| Journal: |
Sci Adv |
| Title: |
Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis. |
| Volume: |
2 |
| Issue: |
7 |
| Pages: |
e1600224 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xi H |
| Year: |
2016 |
| Journal: |
Circ Res |
| Title: |
Caspase-1 Inflammasome Activation Mediates Homocysteine-Induced Pyrop-Apoptosis in Endothelial Cells. |
| Volume: |
118 |
| Issue: |
10 |
| Pages: |
1525-39 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Silveira TN |
| Year: |
2017 |
| Journal: |
Eur J Immunol |
| Title: |
NLRP12 negatively regulates proinflammatory cytokine production and host defense against Brucella abortus. |
| Volume: |
47 |
| Issue: |
1 |
| Pages: |
51-59 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wickstrum JR |
| Year: |
2009 |
| Journal: |
Infect Immun |
| Title: |
Francisella tularensis induces extensive caspase-3 activation and apoptotic cell death in the tissues of infected mice. |
| Volume: |
77 |
| Issue: |
11 |
| Pages: |
4827-36 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hendrikx T |
| Year: |
2013 |
| Journal: |
PLoS One |
| Title: |
Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice. |
| Volume: |
8 |
| Issue: |
12 |
| Pages: |
e78792 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Inserra A |
| Year: |
2019 |
| Journal: |
Sci Rep |
| Title: |
Mice lacking Casp1, Ifngr and Nos2 genes exhibit altered depressive- and anxiety-like behaviour, and gut microbiome composition. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
6456 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Meissner F |
| Year: |
2008 |
| Journal: |
Nat Immunol |
| Title: |
Superoxide dismutase 1 regulates caspase-1 and endotoxic shock. |
| Volume: |
9 |
| Issue: |
8 |
| Pages: |
866-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thomas SM |
| Year: |
2023 |
| Journal: |
Infect Immun |
| Title: |
High Lethality of Mycobacterium tuberculosis Infection in Mice Lacking the Phagocyte Oxidase and Caspase1/11. |
| Volume: |
91 |
| Issue: |
7 |
| Pages: |
e0006023 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fauteux-Daniel S |
| Year: |
2018 |
| Journal: |
J Immunol |
| Title: |
Deletion of Inflammasome Components Is Not Sufficient To Prevent Fatal Inflammation in Models of Familial Hemophagocytic Lymphohistiocytosis. |
| Volume: |
200 |
| Issue: |
11 |
| Pages: |
3769-3776 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Walker WE |
| Year: |
2006 |
| Journal: |
J Immunol |
| Title: |
Absence of innate MyD88 signaling promotes inducible allograft acceptance. |
| Volume: |
177 |
| Issue: |
8 |
| Pages: |
5307-16 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Petrasek J |
| Year: |
2012 |
| Journal: |
J Clin Invest |
| Title: |
IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice. |
| Volume: |
122 |
| Issue: |
10 |
| Pages: |
3476-89 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vincent JA |
| Year: |
2007 |
| Journal: |
Diabetes |
| Title: |
Inhibition of caspase-1/interleukin-1beta signaling prevents degeneration of retinal capillaries in diabetes and galactosemia. |
| Volume: |
56 |
| Issue: |
1 |
| Pages: |
224-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hagar JA |
| Year: |
2013 |
| Journal: |
Science |
| Title: |
Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock. |
| Volume: |
341 |
| Issue: |
6151 |
| Pages: |
1250-3 |
|
•
•
•
•
•
|