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Search results 801 to 824 out of 824 for Inhba

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Type Details Score
Allele
Inhba<tm2Zuk> | MGI:2386671
Name: inhibin beta-A; targeted mutation 2, Martin M Matzuk
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Inhba/Inhba
Background: involves: 129S7/SvEvBrd
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Inhba/Inhba
Background: involves: 129S7/SvEvBrd
Zygosity: hm
Has Mutant Allele: true
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Protein Domain
IPR045716 | CHRDL_1/2_C
Type: Domain
Description: This is the C-terminal domain of Chordin-like proteins 1 and 2 (CHRDL1/2). CHRDL1 antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors []. CHRDL2 inhibit bone morphogenetic proteins (BMPs) activity by blocking their interaction with their receptor []. CHRDL2 may play a role during myoblast and osteoblast differentiation and maturation []. It's worth noting that there are different results regarding its binding partners; according to [], CHRDL2 interacts with INHBA but not BMP2, BMP4 and BMP6.
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Publication
18587495 | -
 
First Author: Kane R
Year: 2008
Journal: Mol Vis
Title: Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis.
Volume: 14
Pages: 1138-48
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Publication
26004914 | J:220890
First Author: Omura T
Year: 2015
Journal: Neuron
Title: Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS.
Volume: 86
Issue: 5
Pages: 1215-27
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Publication
14660436 | J:87049
First Author: Nakayama N
Year: 2004
Journal: Development
Title: A novel chordin-like BMP inhibitor, CHL2, expressed preferentially in chondrocytes of developing cartilage and osteoarthritic joint cartilage.
Volume: 131
Issue: 1
Pages: 229-40
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Publication
15094188 | -
 
First Author: Oren A
Year: 2004
Journal: Gene
Title: hCHL2, a novel chordin-related gene, displays differential expression and complex alternative splicing in human tissues and during myoblast and osteoblast maturation.
Volume: 331
Pages: 17-31
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Protein
F6WCT1
Organism: Mus musculus/domesticus
Length: 221  
Fragment?: true
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Protein Domain
IPR045717 | CHRDL1/2
Type: Family
Description: This entry includes chordin-like protein 1/2 (CHRDL1/2). CHRDL1 antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors []. CHRDL2 inhibit bone morphogenetic proteins (BMPs) activity by blocking their interaction with their receptor []. CHRDL2 may play a role during myoblast and osteoblast differentiation and maturation []. It's worth noting that there are different results regarding its binding partners; according to [], CHRDL2 interacts with INHBA but not BMP2, BMP4 and BMP6.Bone is composed of an organic matrix that is principally collagenous and is mineralised with inorganic crystals of hydroxyapatite. Demineralisation of the bone results in a demineralised bone matrix []. In 1965, Urist M.R demonstrates the decalcified bone matrix (DBM) can induce ectopic bone/cartilage formation []. The morphogens in DBM that induce such skeletogenesis were named as bone morphogenetic proteins (BMPs) []. Since then, more than 20 members of BMPs have been identified. BMPs are potent effectors in almost all crucial biological events, such development, maintenance and regeneration of organs/tissues [].
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Publication
30377784 | J:320325
First Author: Ojima F
Year: 2019
Journal: Cell Tissue Res
Title: Runx3 regulates folliculogenesis and steroidogenesis in granulosa cells of immature mice.
Volume: 375
Issue: 3
Pages: 743-754
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Publication
8833235 | J:32014
First Author: Lahbib-Mansais Y
Year: 1996
Journal: Mamm Genome
Title: Chromosomal localization of homeobox genes and associated markers on porcine chromosomes 3, 5, 12, 15, 16 and 18: comparative mapping study with human and mouse.
Volume: 7
Issue: 3
Pages: 174-9
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Protein
Q920C1
Organism: Mus musculus/domesticus
Length: 447  
Fragment?: false
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Protein
Q8VEA6
Organism: Mus musculus/domesticus
Length: 426  
Fragment?: false
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Protein
A0A0B4J1E8
Organism: Mus musculus/domesticus
Length: 426  
Fragment?: false
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Protein
D3YV59
Organism: Mus musculus/domesticus
Length: 433  
Fragment?: false
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Publication
22209847 | -
First Author: Ohyama Y
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Modulation of matrix mineralization by Vwc2-like protein and its novel splicing isoforms.
Volume: 418
Issue: 1
Pages: 12-6
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Publication
5319761 | -
First Author: Urist MR
Year: 1965
Journal: Science
Title: Bone: formation by autoinduction.
Volume: 150
Issue: 3698
Pages: 893-9
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Publication
19900831 | -
First Author: Reddi AH
Year: 2009
Journal: Cytokine Growth Factor Rev
Title: Bone morphogenetic proteins (BMPs): from morphogens to metabologens.
Volume: 20
Issue: 5-6
Pages: 341-2
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Publication
28235253 | J:286221
First Author: Wijayarathna R
Year: 2017
Journal: Andrology
Title: Activin and follistatin interactions in the male reproductive tract: activin expression and morphological abnormalities in mice lacking follistatin 288.
Volume: 5
Issue: 3
Pages: 578-588
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Protein
Q3TP73
Organism: Mus musculus/domesticus
Length: 333  
Fragment?: false
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Protein
A0A140LIV5
Organism: Mus musculus/domesticus
Length: 159  
Fragment?: true
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Protein
Q6NXY0
Organism: Mus musculus/domesticus
Length: 333  
Fragment?: false
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Publication
- | J:4884
 
First Author: Barton DE
Year: 1987
Journal: Cytogenet Cell Genet
Title: INHA, INHBA, and INHBB, the loci for the three subunits of inhibin, mapped in mouse and man.
Volume: 46
Pages: 578 (Abstr.)
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