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Search results 801 to 900 out of 2308 for Lep

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:501707
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825899
Age: embryonic day 14.5
Image: euxassay_002219_18
Specimen Label: euxassay_002219_18
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:501707
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825899
Age: embryonic day 14.5
Image: euxassay_002219_19
Specimen Label: euxassay_002219_19
Detected: true
Specimen Num: 16
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•
GXD Expression
GXD Expression
 
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160464
Pattern: Regionally restricted
Stage: TS04
Assay Id: MGI:6201098
Age: embryonic day 3.5
Note: Reduced expression in trophoblast. Expression localized to apical surface of individual trophoblast cells.
Specimen Label: 6D
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
 
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160464
Pattern: Regionally restricted
Stage: TS04
Assay Id: MGI:6201098
Age: embryonic day 3.5
Note: Reduced expression in trophoblast. Expression localized to apical surface of individual trophoblast cells.
Specimen Label: 6E upper
Detected: true
Specimen Num: 21
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•
GXD Expression
GXD Expression
 
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160464
Pattern: Regionally restricted
Stage: TS04
Assay Id: MGI:6201098
Age: embryonic day 3.5
Note: Reduced expression in trophoblast. Expression localized to apical surface of individual trophoblast cells.
Specimen Label: 6E lower
Detected: true
Specimen Num: 22
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•
GXD Expression
GXD Expression
 
Probe: MGI:501707
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825899
Age: embryonic day 14.5
Image: euxassay_002219_04
Specimen Label: euxassay_002219_04
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
 
Probe: MGI:501707
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825899
Age: embryonic day 14.5
Image: euxassay_002219_05
Specimen Label: euxassay_002219_05
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
 
Probe: MGI:501707
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825899
Age: embryonic day 14.5
Image: euxassay_002219_15
Specimen Label: euxassay_002219_15
Detected: true
Specimen Num: 12
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•
GXD Expression
GXD Expression
 
Probe: MGI:501707
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825899
Age: embryonic day 14.5
Image: euxassay_002219_16
Specimen Label: euxassay_002219_16
Detected: true
Specimen Num: 13
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•
GXD Expression
GXD Expression
 
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6201098
Age: postnatal adult
Note: Authors report expression was localized asymmetrically. Distinct domain of intense expression.
Specimen Label: 1A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6201098
Age: postnatal adult
Note: Most expression concentrated in one portion of oocyte and extended from plasma membrane into subplasmalemmal cytoplasm. Intense expression extended through tranzonal processes to surface of oocyte.
Specimen Label: 1B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6201098
Age: postnatal adult
Note: Authors report polarized pattern expression virtually identical to oocytes of normal animals (e.g. Figure 1A).
Specimen Label: 5H
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
 
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6201098
Age: postnatal adult
Note: Authors state germinal vesicle oocytes from C57BL/Ks db/db mice exhibited a polarized pattern expression virtually identical to oocytes of normal animals (e.g. Figure 1A).
Specimen Label: C57BL/Ks db/db not shown
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
 
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6201098
Age: postnatal adult
Note: Expression in corresponding portion of oocyte.
Specimen Label: 7C
Detected: true
Specimen Num: 31
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GXD Expression
GXD Expression
 
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6201098
Age: postnatal adult
Note: Expression in corresponding portion of oocyte.
Specimen Label: 7D
Detected: true
Specimen Num: 32
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GXD Expression
GXD Expression
   
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6201098
Age: postnatal adult
Specimen Label: 7K
Detected: true
Specimen Num: 33
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3592628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691002
Age: postnatal adult
Image: BCM_1467424
Specimen Label: BCM_1467424
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Not Specified
Stage: TS02
Assay Id: MGI:6201098
Age: embryonic day 1.0
Specimen Label: 1G
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Not Specified
Stage: TS02
Assay Id: MGI:6201098
Age: embryonic day 1.0
Specimen Label: 1H
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Regionally restricted
Stage: TS02
Assay Id: MGI:6201098
Age: embryonic day 1.0
Note: Authors report absence of expression in an internal section.
Specimen Label: 2B
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Regionally restricted
Stage: TS02
Assay Id: MGI:6201098
Age: embryonic day 1.0
Note: Authors state first cleavage furrow develops in expression domain containing second polar body. Each blastomere characterized by intense expression in subplasmalemmal cytoplasm, diminishing progressively in subjacent cortical cytoplasm.
Specimen Label: 2C
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Regionally restricted
Stage: TS02
Assay Id: MGI:6201098
Age: embryonic day 1.5
Note: Authors report high level of expression in blastomere 1; reduced expression in blastomeres 2 and 3.
Specimen Label: 2D
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Not Specified
Stage: TS02
Assay Id: MGI:6201098
Age: embryonic day 1.5
Specimen Label: 2E
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Not Specified
Stage: TS02
Assay Id: MGI:6201098
Age: embryonic day 1.5
Specimen Label: 2F
Detected: true
Specimen Num: 12
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:501707
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825899
Age: embryonic day 14.5
Image: euxassay_002219_05
Specimen Label: euxassay_002219_05
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Present
Sex: Female
Emaps: EMAPS:3562728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6201098
Age: postnatal adult
Note: Authors report most intense expression in region of cumulus and coronal cells associated wtih oolemma and subjacent ooplasm with most intense expression. Intense expression extended through tranzonal processes to surface of oocyte.
Specimen Label: 1A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6201079
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-04
Strength: Present
Sex: Female
Emaps: EMAPS:3562728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6201098
Age: postnatal adult
Note: Intense expression in zona pellucida-associated coronal cell processes.
Specimen Label: 5H
Detected: true
Specimen Num: 18
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Publication
19737935 | J:306777
First Author: Bu SY
Year: 2009
Journal: J Biol Chem
Title: Suppression of long chain acyl-CoA synthetase 3 decreases hepatic de novo fatty acid synthesis through decreased transcriptional activity.
Volume: 284
Issue: 44
Pages: 30474-83
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Publication
12244109 | J:80546
First Author: Xia Z
Year: 2002
Journal: J Biol Chem
Title: Acylation-stimulating protein (ASP) deficiency induces obesity resistance and increased energy expenditure in ob/ob mice.
Volume: 277
Issue: 48
Pages: 45874-9
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Publication
11956242 | J:76091
First Author: Chen HC
Year: 2002
Journal: J Clin Invest
Title: Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1.
Volume: 109
Issue: 8
Pages: 1049-55
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Publication
20368432 | J:159285
First Author: Olson DP
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake.
Volume: 107
Issue: 16
Pages: 7598-603
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Publication
17068142 | J:129554
First Author: Liu Y
Year: 2007
Journal: Endocrinology
Title: Deficiency of adiponectin receptor 2 reduces diet-induced insulin resistance but promotes type 2 diabetes.
Volume: 148
Issue: 2
Pages: 683-92
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Publication
23291629 | J:194928
First Author: Liew CW
Year: 2013
Journal: Nat Med
Title: Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance.
Volume: 19
Issue: 2
Pages: 217-26
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Publication
17906635 | J:130031
First Author: Matsuzaka T
Year: 2007
Journal: Nat Med
Title: Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance.
Volume: 13
Issue: 10
Pages: 1193-202
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Publication
29046435 | J:283184
 
First Author: Xiong Y
Year: 2017
Journal: Sci Transl Med
Title: Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys.
Volume: 9
Issue: 412
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Publication
18654634 | J:138216
First Author: Dokmanovic-Chouinard M
Year: 2008
Journal: PLoS Genet
Title: Positional cloning of "Lisch-Like", a candidate modifier of susceptibility to type 2 diabetes in mice.
Volume: 4
Issue: 7
Pages: e1000137
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Publication
23826244 | J:204339
First Author: Watanabe K
Year: 2013
Journal: PLoS One
Title: ILDR2: an endoplasmic reticulum resident molecule mediating hepatic lipid homeostasis.
Volume: 8
Issue: 6
Pages: e67234
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Publication
17482547 | J:187736
First Author: Wellen KE
Year: 2007
Journal: Cell
Title: Coordinated regulation of nutrient and inflammatory responses by STAMP2 is essential for metabolic homeostasis.
Volume: 129
Issue: 3
Pages: 537-48
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Publication
21998599 | J:178002
First Author: Bhatnagar S
Year: 2011
Journal: PLoS Genet
Title: Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion.
Volume: 7
Issue: 10
Pages: e1002323
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Publication
18070594 | J:172974
First Author: Dong J
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Role of modulator recognition factor 2 in adipogenesis and leptin expression in 3T3-L1 cells.
Volume: 366
Issue: 2
Pages: 551-5
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Publication
24947615 | J:224583
 
First Author: Park HW
Year: 2014
Journal: Nat Commun
Title: Hepatoprotective role of Sestrin2 against chronic ER stress.
Volume: 5
Pages: 4233
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Publication
17932511 | J:283446
First Author: McKay RM
Year: 2007
Journal: EMBO Rep
Title: Tripeptidyl peptidase II promotes fat formation in a conserved fashion.
Volume: 8
Issue: 12
Pages: 1183-9
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Publication
7984236 | J:20512
First Author: Zhang Y
Year: 1994
Journal: Nature
Title: Positional cloning of the mouse obese gene and its human homologue.
Volume: 372
Issue: 6505
Pages: 425-32
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Publication
15899045 | J:228116
First Author: Otero M
Year: 2005
Journal: Arthritis Res Ther
Title: Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: synergistic effect of leptin with interleukin-1.
Volume: 7
Issue: 3
Pages: R581-91
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Publication
28694473 | J:253033
First Author: Kwak HJ
Year: 2017
Journal: Sci Rep
Title: 5-LO inhibition ameliorates palmitic acid-induced ER stress, oxidative stress and insulin resistance via AMPK activation in murine myotubes.
Volume: 7
Issue: 1
Pages: 5025
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Publication
9590691 | J:47476
First Author: Kristensen P
Year: 1998
Journal: Nature
Title: Hypothalamic CART is a new anorectic peptide regulated by leptin.
Volume: 393
Issue: 6680
Pages: 72-6
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Publication
24645678 | J:214138
First Author: Chen Z
Year: 2014
Journal: Mol Endocrinol
Title: SH2B1 in β-cells promotes insulin expression and glucose metabolism in mice.
Volume: 28
Issue: 5
Pages: 696-705
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Publication
18292187 | J:145382
First Author: Pan W
Year: 2008
Journal: Endocrinology
Title: Astrocyte leptin receptor (ObR) and leptin transport in adult-onset obese mice.
Volume: 149
Issue: 6
Pages: 2798-806
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Publication
12114623 | J:107879
First Author: Cohen P
Year: 2002
Journal: Science
Title: Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss.
Volume: 297
Issue: 5579
Pages: 240-3
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Publication
15096593 | J:89545
First Author: Dobrzyn P
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver.
Volume: 101
Issue: 17
Pages: 6409-14
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Publication
15562249 | J:96073
First Author: Dobrzyn A
Year: 2005
Journal: Am J Physiol Endocrinol Metab
Title: Stearoyl-CoA desaturase-1 deficiency reduces ceramide synthesis by downregulating serine palmitoyltransferase and increasing beta-oxidation in skeletal muscle.
Volume: 288
Issue: 3
Pages: E599-607
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Publication
24586592 | J:213762
First Author: Shemesh A
Year: 2014
Journal: PLoS One
Title: The antidepressant trans-2-phenylcyclopropylamine protects mice from high-fat-diet-induced obesity.
Volume: 9
Issue: 2
Pages: e89199
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Publication
27500833 | J:251640
First Author: Wang X
Year: 2016
Journal: PLoS One
Title: Sirtuin-2 Regulates Sepsis Inflammation in ob/ob Mice.
Volume: 11
Issue: 8
Pages: e0160431
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Publication
21169216 | J:169023
First Author: Ghamari-Langroudi M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Multinodal regulation of the arcuate/paraventricular nucleus circuit by leptin.
Volume: 108
Issue: 1
Pages: 355-60
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Publication
27239029 | J:238102
First Author: Nutter CA
Year: 2016
Journal: Cell Rep
Title: Dysregulation of RBFOX2 Is an Early Event in Cardiac Pathogenesis of Diabetes.
Volume: 15
Issue: 10
Pages: 2200-2213
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Publication
22268099 | J:185386
First Author: Trevaskis JL
Year: 2012
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Glucagon-like peptide-1 receptor agonism improves metabolic, biochemical, and histopathological indices of nonalcoholic steatohepatitis in mice.
Volume: 302
Issue: 8
Pages: G762-72
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Publication
26824363 | J:234032
First Author: Levenson AE
Year: 2016
Journal: Endocrinology
Title: Effect of Leptin Replacement on PCSK9 in ob/ob Mice and Female Lipodystrophic Patients.
Volume: 157
Issue: 4
Pages: 1421-9
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Publication
21572010 | J:173236
First Author: Taguchi K
Year: 2011
Journal: Am J Physiol Heart Circ Physiol
Title: Dysfunction of endothelium-dependent relaxation to insulin via PKC-mediated GRK2/Akt activation in aortas of ob/ob mice.
Volume: 301
Issue: 2
Pages: H571-83
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Publication
23413430 | J:217970
First Author: Chen JY
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Increased aortic stiffness and attenuated lysyl oxidase activity in obesity.
Volume: 33
Issue: 4
Pages: 839-46
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Publication
18310351 | J:136571
First Author: Ordway D
Year: 2008
Journal: J Leukoc Biol
Title: Animal model of Mycobacterium abscessus lung infection.
Volume: 83
Issue: 6
Pages: 1502-11
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Publication
12970157 | J:87246
First Author: Hochgeschwender U
Year: 2003
Journal: Endocrinology
Title: Altered glucose homeostasis in proopiomelanocortin-null mouse mutants lacking central and peripheral melanocortin.
Volume: 144
Issue: 12
Pages: 5194-202
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Publication
17526026 | J:278213
First Author: Huang J
Year: 2007
Journal: Hepatology
Title: Molecular characterization of the role of orphan receptor small heterodimer partner in development of fatty liver.
Volume: 46
Issue: 1
Pages: 147-57
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Publication
20074524 | J:157004
First Author: Hedbacker K
Year: 2010
Journal: Cell Metab
Title: Antidiabetic effects of IGFBP2, a leptin-regulated gene.
Volume: 11
Issue: 1
Pages: 11-22
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Publication
25730108 | J:222118
First Author: Arble DM
Year: 2015
Journal: Endocrinology
Title: The melanocortin-4 receptor integrates circadian light cues and metabolism.
Volume: 156
Issue: 5
Pages: 1685-91
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Publication
25774553 | J:222169
First Author: Assini JM
Year: 2015
Journal: Endocrinology
Title: Naringenin prevents obesity, hepatic steatosis, and glucose intolerance in male mice independent of fibroblast growth factor 21.
Volume: 156
Issue: 6
Pages: 2087-102
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Publication
26943364 | J:234354
First Author: Kitada Y
Year: 2016
Journal: Endocrinology
Title: Blockade of Sphingosine 1-Phosphate Receptor 2 Signaling Attenuates High-Fat Diet-Induced Adipocyte Hypertrophy and Systemic Glucose Intolerance in Mice.
Volume: 157
Issue: 5
Pages: 1839-51
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Publication
22067317 | J:181652
First Author: Hale C
Year: 2012
Journal: Endocrinology
Title: Lack of overt FGF21 resistance in two mouse models of obesity and insulin resistance.
Volume: 153
Issue: 1
Pages: 69-80
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36161959 | J:340251
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