| Type |
Details |
Score |
| Publication |
| First Author: |
Weckbach LT |
| Year: |
2014 |
| Journal: |
Blood |
| Title: |
The cytokine midkine supports neutrophil trafficking during acute inflammation by promoting adhesion via β2 integrins (CD11/CD18). |
| Volume: |
123 |
| Issue: |
12 |
| Pages: |
1887-96 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Masuda T |
| Year: |
2017 |
| Journal: |
Am J Pathol |
| Title: |
Growth Factor Midkine Promotes T-Cell Activation through Nuclear Factor of Activated T Cells Signaling and Th1 Cell Differentiation in Lupus Nephritis. |
| Volume: |
187 |
| Issue: |
4 |
| Pages: |
740-751 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Igakura T |
| Year: |
1998 |
| Journal: |
Dev Biol |
| Title: |
A null mutation in basigin, an immunoglobulin superfamily member, indicates its important roles in peri-implantation development and spermatogenesis. |
| Volume: |
194 |
| Issue: |
2 |
| Pages: |
152-65 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Weckbach LT |
| Year: |
2019 |
| Journal: |
J Exp Med |
| Title: |
Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis. |
| Volume: |
216 |
| Issue: |
2 |
| Pages: |
350-368 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adachi Y |
| Year: |
1996 |
| Journal: |
Oncogene |
| Title: |
Midkine as a novel target gene for the Wilms' tumor suppressor gene (WT1). |
| Volume: |
13 |
| Issue: |
10 |
| Pages: |
2197-203 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mitsiadis TA |
| Year: |
1995 |
| Journal: |
Development |
| Title: |
Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelial-mesenchymal interactions during fetal development and organogenesis. |
| Volume: |
121 |
| Issue: |
1 |
| Pages: |
37-51 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Obama H |
| Year: |
1995 |
| Journal: |
J Biochem |
| Title: |
Midkine (MK) expression in extraembryonic tissues, amniotic fluid, and cerebrospinal fluid during mouse embryogenesis. |
| Volume: |
118 |
| Issue: |
1 |
| Pages: |
88-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mitsiadis TA |
| Year: |
2008 |
| Journal: |
Dev Biol |
| Title: |
The large functional spectrum of the heparin-binding cytokines MK and HB-GAM in continuously growing organs: the rodent incisor as a model. |
| Volume: |
320 |
| Issue: |
1 |
| Pages: |
256-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lautz T |
| Year: |
2018 |
| Journal: |
EBioMedicine |
| Title: |
Midkine Controls Arteriogenesis by Regulating the Bioavailability of Vascular Endothelial Growth Factor A and the Expression of Nitric Oxide Synthase 1 and 3. |
| Volume: |
27 |
|
| Pages: |
237-246 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wallin J |
| Year: |
1993 |
| Journal: |
Mamm Genome |
| Title: |
A new Pax gene, Pax-9, maps to mouse chromosome 12. |
| Volume: |
4 |
| Issue: |
7 |
| Pages: |
354-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kaplan F |
| Year: |
2003 |
| Journal: |
Am J Respir Cell Mol Biol |
| Title: |
The growth factor midkine is modulated by both glucocorticoid and retinoid in fetal lung development. |
| Volume: |
28 |
| Issue: |
1 |
| Pages: |
33-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cohen S |
| Year: |
2012 |
| Journal: |
J Immunol |
| Title: |
The cytokine midkine and its receptor RPTPζ regulate B cell survival in a pathway induced by CD74. |
| Volume: |
188 |
| Issue: |
1 |
| Pages: |
259-69 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Simon-Chazottes D |
| Year: |
1992 |
| Journal: |
Mamm Genome |
| Title: |
Chromosomal localization of two cell surface-associated molecules of potential importance in development: midkine (Mdk) and basigin (Bsg). |
| Volume: |
2 |
| Issue: |
4 |
| Pages: |
269-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Haas IG |
| Year: |
1992 |
| Journal: |
Mamm Genome |
| Title: |
The gene coding for the immunoglobulin heavy chain binding protein BiP (Hsce-70) maps to mouse chromosome 2. |
| Volume: |
3 |
| Issue: |
11 |
| Pages: |
659-60 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Reynolds PR |
| Year: |
2003 |
| Journal: |
Dev Dyn |
| Title: |
Thyroid transcription factor (TTF) -1 regulates the expression of midkine (MK) during lung morphogenesis. |
| Volume: |
227 |
| Issue: |
2 |
| Pages: |
227-37 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen Q |
| Year: |
2005 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Transiently truncated and differentially regulated expression of midkine during mouse embryogenesis. |
| Volume: |
330 |
| Issue: |
4 |
| Pages: |
1230-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang YH |
| Year: |
2008 |
| Journal: |
Arterioscler Thromb Vasc Biol |
| Title: |
Suppression of the Raf/MEK/ERK signaling cascade and inhibition of angiogenesis by the carboxyl terminus of angiopoietin-like protein 4. |
| Volume: |
28 |
| Issue: |
5 |
| Pages: |
835-40 |
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•
•
•
•
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| Publication |
| First Author: |
Orthofer M |
| Year: |
2020 |
| Journal: |
Cell |
| Title: |
Identification of ALK in Thinness. |
| Volume: |
181 |
| Issue: |
6 |
| Pages: |
1246-1262.e22 |
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•
•
•
•
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| Publication |
| First Author: |
Olmeda D |
| Year: |
2017 |
| Journal: |
Nature |
| Title: |
Whole-body imaging of lymphovascular niches identifies pre-metastatic roles of midkine. |
| Volume: |
546 |
| Issue: |
7660 |
| Pages: |
676-680 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hardie WD |
| Year: |
2007 |
| Journal: |
Am J Respir Cell Mol Biol |
| Title: |
Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis. |
| Volume: |
37 |
| Issue: |
3 |
| Pages: |
309-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chan P |
| Year: |
1994 |
| Journal: |
Genomics |
| Title: |
Comparative mapping of lipocalin genes in human and mouse: the four genes for complement C8 gamma chain, prostaglandin-D-synthase, oncogene-24p3, and progestagen-associated endometrial protein map to HSA9 and MMU2. |
| Volume: |
23 |
| Issue: |
1 |
| Pages: |
145-50 |
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•
•
•
•
•
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| Publication |
| First Author: |
Jochheim-Richter A |
| Year: |
2006 |
| Journal: |
Differentiation |
| Title: |
Gene expression analysis identifies novel genes participating in early murine liver development and adult liver regeneration. |
| Volume: |
74 |
| Issue: |
4 |
| Pages: |
167-73 |
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•
•
•
•
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| First Author: |
Peichel CL |
| Year: |
1996 |
| Journal: |
Genetics |
| Title: |
Genetic and physical mapping of the mouse Ulnaless locus. |
| Volume: |
144 |
| Issue: |
4 |
| Pages: |
1757-67 |
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•
•
•
•
•
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| Publication |
| First Author: |
Mitsiadis TA |
| Year: |
2010 |
| Journal: |
Development |
| Title: |
BMPs and FGFs target Notch signalling via jagged 2 to regulate tooth morphogenesis and cytodifferentiation. |
| Volume: |
137 |
| Issue: |
18 |
| Pages: |
3025-35 |
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•
•
•
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| First Author: |
Fazilaty H |
| Year: |
2021 |
| Journal: |
Cell Rep |
| Title: |
Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage. |
| Volume: |
36 |
| Issue: |
5 |
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•
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•
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| First Author: |
Tou L |
| Year: |
2004 |
| Journal: |
Mol Cell Biol |
| Title: |
Regulation of mammalian epithelial differentiation and intestine development by class I histone deacetylases. |
| Volume: |
24 |
| Issue: |
8 |
| Pages: |
3132-9 |
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•
•
•
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| First Author: |
Naveau A |
| Year: |
2017 |
| Journal: |
J Bone Miner Res |
| Title: |
Isl1 Controls Patterning and Mineralization of Enamel in the Continuously Renewing Mouse Incisor. |
| Volume: |
32 |
| Issue: |
11 |
| Pages: |
2219-2231 |
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•
•
•
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| First Author: |
Kim IM |
| Year: |
2005 |
| Journal: |
J Biol Chem |
| Title: |
The forkhead box m1 transcription factor is essential for embryonic development of pulmonary vasculature. |
| Volume: |
280 |
| Issue: |
23 |
| Pages: |
22278-86 |
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•
•
•
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| First Author: |
Lovgren AK |
| Year: |
2007 |
| Journal: |
Mol Cell Biol |
| Title: |
cPGES/p23 is required for glucocorticoid receptor function and embryonic growth but not prostaglandin E2 synthesis. |
| Volume: |
27 |
| Issue: |
12 |
| Pages: |
4416-30 |
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•
•
•
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| First Author: |
Park YK |
| Year: |
2005 |
| Journal: |
Genesis |
| Title: |
Gene expression profile analysis of mouse colon embryonic development. |
| Volume: |
41 |
| Issue: |
1 |
| Pages: |
1-12 |
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•
•
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•
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| First Author: |
Price KL |
| Year: |
2009 |
| Journal: |
J Urol |
| Title: |
Unraveling the genetic landscape of bladder development in mice. |
| Volume: |
181 |
| Issue: |
5 |
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2366-74 |
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Negretti NM |
| Year: |
2021 |
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Development |
| Title: |
A single-cell atlas of mouse lung development. |
| Volume: |
148 |
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24 |
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| First Author: |
Steele-Perkins G |
| Year: |
2005 |
| Journal: |
Mol Cell Biol |
| Title: |
The transcription factor gene Nfib is essential for both lung maturation and brain development. |
| Volume: |
25 |
| Issue: |
2 |
| Pages: |
685-98 |
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| First Author: |
Inoue S |
| Year: |
2014 |
| Journal: |
Hum Mol Genet |
| Title: |
New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome. |
| Volume: |
23 |
| Issue: |
24 |
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6553-66 |
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| First Author: |
Chen PC |
| Year: |
2010 |
| Journal: |
J Clin Invest |
| Title: |
Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome–associated Sos1 mutation. |
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120 |
| Issue: |
12 |
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| First Author: |
Singh R |
| Year: |
2012 |
| Journal: |
Cell Mol Life Sci |
| Title: |
Tbx2 and Tbx3 induce atrioventricular myocardial development and endocardial cushion formation. |
| Volume: |
69 |
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1377-89 |
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Drake TA |
| Year: |
2001 |
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J Orthop Res |
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Genetic loci influencing natural variations in femoral bone morphometry in mice. |
| Volume: |
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Angelozzi M |
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2022 |
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Cell Rep |
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Single-cell atlas of craniogenesis uncovers SOXC-dependent, highly proliferative, and myofibroblast-like osteodermal progenitors. |
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Xie X |
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2023 |
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FASEB J |
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SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. |
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Ficker M |
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2004 |
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Dev Biol |
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Analysis of genes from inner ear developmental-stage cDNA subtraction reveals molecular regionalization of the otic capsule. |
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Lepourcelet M |
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Development |
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Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF). |
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Hum Mol Genet |
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Gene expression in pharyngeal arch 1 during human embryonic development. |
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Endocrinology |
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Obesity and High-Fat Diet Induce Distinct Changes in Placental Gene Expression and Pregnancy Outcome. |
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Lanctot AA |
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Spatially dependent dynamic MAPK modulation by the Nde1-Lis1-Brap complex patterns mammalian CNS. |
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Adv Sci (Weinh) |
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Isl Identifies the Extraembryonic Mesodermal/Allantois Progenitors and is Required for Placenta Morphogenesis and Vasculature Formation. |
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Nucleic Acids Res |
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Mutagenesis of diploid mammalian genes by gene entrapment. |
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Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. |
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Rutledge EA |
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Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. |
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Cereb Cortex |
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PLoS One |
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Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. |
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Brain Res Mol Brain Res |
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A neurogenomics approach to gene expression analysis in the developing brain. |
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BMC Genomics |
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Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. |
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Magdaleno S |
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2006 |
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PLoS Biol |
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BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
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4 |
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4 |
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e86 |
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Adams DJ |
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2024 |
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Nature |
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Genetic determinants of micronucleus formation in vivo. |
| Volume: |
627 |
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8002 |
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MGD Nomenclature Committee |
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Nomenclature Committee Use |
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Zambrowicz BP |
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2003 |
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Proc Natl Acad Sci U S A |
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Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
| Volume: |
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24 |
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14109-14 |
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GemPharmatech |
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GemPharmatech Website. |
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Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
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2008 |
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Database Download |
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Mouse Gene Trap Data Load from dbGSS |
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Cyagen Biosciences Inc. |
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Cyagen Biosciences Website. |
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AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
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Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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| First Author: |
UniProt-GOA |
| Year: |
2012 |
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| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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| First Author: |
Okazaki Y |
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2002 |
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Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
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6915 |
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| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
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Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Diez-Roux G |
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PLoS Biol |
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A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
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Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
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| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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| First Author: |
MGI Genome Annotation Group and UniGene Staff |
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2015 |
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Database Download |
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MGI-UniGene Interconnection Effort |
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Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
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2010 |
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Annotation inferences using phylogenetic trees |
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Mouse Genome Database and National Center for Biotechnology Information |
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2000 |
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Database Release |
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Entrez Gene Load |
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| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
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| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
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| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
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| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
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| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
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| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
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| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
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•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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| Pathway |
|
•
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•
•
•
|
| Allele |
| Name: |
midkine; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1621
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
140
 |
| Fragment?: |
false |
|
•
•
•
•
•
|