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Search results 801 to 900 out of 935 for Nf1

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Type Details Score
HT Experiment
GSE189189 | RNA sequencing of mouse sciatic nerve to characterize blood-nerve-barrier gene expression in Nf1 deficient mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
17380155 | J:139271
First Author: Piddubnyak V
Year: 2007
Journal: Cell Death Differ
Title: Positive regulation of apoptosis by HCA66, a new Apaf-1 interacting protein, and its putative role in the physiopathology of NF1 microdeletion syndrome patients.
Volume: 14
Issue: 6
Pages: 1222-33
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Publication
10863097 | J:76178
First Author: Kehrer-Sawatzki H
Year: 2000
Journal: Gene
Title: Characterization of the Fugu rubripes NLK and FN5 genes flanking the NF1 (Neurofibromatosis type 1) gene in the 5' direction and mapping of the human counterparts.
Volume: 251
Issue: 1
Pages: 63-71
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Allele
Tg(MMTV-Erbb2)NA1Mul | MGI:3039244
Name: transgene insertion NA1, William Muller
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(MMTV-Erbb2)NA1Mul/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Publication
8939902 | J:36851
First Author: Furlong EE
Year: 1996
Journal: J Biol Chem
Title: Expression of a 74-kDa nuclear factor 1 (NF1) protein is induced in mouse mammary gland involution. Involution-enhanced occupation of a twin NF1 binding element in the testosterone-repressed prostate message-2/clusterin promoter.
Volume: 271
Issue: 47
Pages: 29688-97
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Allele
Nf1<tm1Fcr> | MGI:1857444
Name: neurofibromin 1; targeted mutation 1, Fredrick Cancer Research and Development Center
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Nf1<em1Smoc> | MGI:7291290
Name: neurofibromin 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Nf1/Nf1
Background: either: (involves: 129S/SvEv) or (involves: 129S/SvEv * C57BL/6J)
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1<+> Trp53/Trp53<+>
Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
17632510 | -
First Author: Douglas J
Year: 2007
Journal: Nat Genet
Title: Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth.
Volume: 39
Issue: 8
Pages: 963-5
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Strain
MGI:6770966 | C57BL/6JSmoc-N<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Nf1/Nf1 Tg(GFAP-cre)#Gtm/?
Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Publication
31036704 | J:285455
 
First Author: Wang X
Year: 2019
Journal: EMBO Mol Med
Title: Nf1 loss promotes Kras-driven lung adenocarcinoma and results in Psat1-mediated glutamate dependence.
Volume: 11
Issue: 6
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DO Term
DOID:0070483 | Watson syndrome
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Publication
20506354 | -
First Author: Bengesser K
Year: 2010
Journal: Hum Mutat
Title: A novel third type of recurrent NF1 microdeletion mediated by nonallelic homologous recombination between LRRC37B-containing low-copy repeats in 17q11.2.
Volume: 31
Issue: 6
Pages: 742-51
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Allele
Nf1<tm1Smoc> | MGI:7291291
Name: neurofibromin 1; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Nf1<tm1Tyj> | MGI:1857478
Name: neurofibromin 1; targeted mutation 1, Tyler Jacks
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Nf1<tm1Cbr> | MGI:2137365
Name: neurofibromin 1; targeted mutation 1, Camilyn Brannan
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Nf1<Mhdadsk9> | MGI:2682223
 
Name: neurofibromin 1; Martin Hrabe de Angelis dark skin 9
Allele Type: Chemically induced (ENU)
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Allele
Nf1<tm1c(KOMP)Wtsi> | MGI:6153138
Name: neurofibromin 1; targeted mutation 1c, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready
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DO Term
DOID:0111683 | neurofibromatosis-Noonan syndrome
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HT Experiment
E-GEOD-42603 | The data of differentially regulated exons from mouse testes - wild-type and Dazap1 mutant
Series Id: GSE42603
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
10360836 | -
First Author: Kaufmann D
Year: 1999
Journal: DNA Cell Biol
Title: EVI2B, a gene lying in an intron of the neurofibromatosis type 1 (NF1) gene, is as the NF1 gene involved in differentiation of melanocytes and keratinocytes and is overexpressed in cells derived from NF1 neurofibromas.
Volume: 18
Issue: 5
Pages: 345-56
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Strain
MGI:6429246 | C57BL/6JSmoc-Nf1<tm1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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Allele
Nf1<tm1Par> | MGI:2176057
Name: neurofibromin 1; targeted mutation 1, Luis F Parada
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Genotype
Genotype
Symbol: Nf1/Nf1<+>
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1
Background: involves: 129S1/Sv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1 Tg(Syn1-cre)671Jxm/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1<+> Trp53/Trp53<+>
Background: involves: 129/Sv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1<+>
Background: involves: 129S2/SvPas * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Grin1/Grin1<+> Nf1/Nf1<+>
Background: involves: 129S2/SvPas * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1 Tg(Mpz-cre)94Imeg/?
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1 Tg(Pax3-cre)1Joe/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1 H2az2/H2az2<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1 Tg(Fabp7-cre,-lacZ)3Gtm/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Pten/Pten<+> Tg(Gfap-cre)77.6Mvs/?
Background: involves: 129S4/SvJae * BALB/c * C57BL/6NHsd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1 Tg(Prrx1-cre)1Cjt/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1 Tg(Prrx1-cre)1Cjt/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * C57BL/6N * SJL/J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1 Tg(Dhh-cre)1Mejr/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N * C57BL/6NTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1 Tg(Dhh-cre)1Mejr/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1<+>
Background: involves: C3HeB/FeJ * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Publication
2898299 | J:48632
First Author: Muller WJ
Year: 1988
Journal: Cell
Title: Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene.
Volume: 54
Issue: 1
Pages: 105-15
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HT Experiment
E-GEOD-29343 | Neurofibromin (Nf1) is required for skeletal muscle development
Series Id: GSE29343
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Strain
MGI:5651590 | either: (involves: 129-Nf1<tm1Fcr>) or (involves: 129S6/SvEvTac * C57BL/6J)
Attribute String: mutant strain, targeted mutation
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Strain
MGI:5653868 | either: (involves: 129-Nf1<tm1Fcr>) or (involves: 129S/SvEv * C57BL/6J)
Attribute String: Not specified
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Strain
MGI:3618485 | B6.129S6-Nf1<tm1Fcr>/Nci
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:3618484 | 129-Nf1<tm1Fcr>/Nci
Attribute String: targeted mutation, mutant strain
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Strain
MGI:2161573 | B6.129S6-Nf1<tm1Fcr>/J
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Nf1/Nf1
Background: involves: 129S/SvEv
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1
Background: involves: 129 * 129S/SvEv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1
Background: involves: 129 * 129S/SvEv * C3H * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1<+> Trp53/Trp53
Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1<+> Tg(GFAP-cre)#Gtm/?
Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1<+> Tg(Cnp-EGFR)10Nrat/?
Background: involves: 129S/SvEv * C57BL/6 * SJL
Zygosity: cx
Has Mutant Allele: true
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Publication
18984150 | J:143214
First Author: Reilly KM
Year: 2008
Journal: Cell
Title: It takes a (dysfunctional) village to raise a tumor.
Volume: 135
Issue: 3
Pages: 408-10
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Publication
25517743 | J:217735
First Author: Gutmann DH
Year: 2014
Journal: Cancer Cell
Title: NF GEMMs already! The power and promise of mouse tumor models.
Volume: 26
Issue: 5
Pages: 596-9
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Publication
15257284 | J:92164
First Author: Wulf G
Year: 2004
Journal: EMBO J
Title: Modeling breast cancer in vivo and ex vivo reveals an essential role of Pin1 in tumorigenesis.
Volume: 23
Issue: 16
Pages: 3397-407
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HT Experiment
GSE235594 | A common single nucleotide variant in the cytokine receptor-like factor-3 (CRLF3) gene causes neuronal deficits in human and mouse cells
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Strain
MGI:5485395 | B6.129-Trp53<tm1Brd> Nf1<tm1Fcr>
Attribute String: mutant strain, targeted mutation, congenic
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Genotype
Genotype
Symbol: Nf1/Nf1
Background: involves: 129S/SvEv * 129S1/Sv * 129S2/SvPas * 129X1/SvJ
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hprt1/Hprt1<+> Nf1/Nf1
Background: involves: 129S/SvEv * 129S/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Hprt1/Hprt1<+> Nf1/Nf1
Background: involves: 129S/SvEv * 129S/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1 Pax3/Pax3<+>
Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1<+> Tsc1/Tsc1 Tg(GFAP-cre)#Gtm/?
Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1<+> Trp53/Trp53<+>
Background: B6.129-Trp53 Nf1
Zygosity: cx
Has Mutant Allele: true
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Publication
1916815 | J:11478
First Author: Xu WM
Year: 1991
Journal: Genomics
Title: The gene for von Recklinghausen neurofibromatosis (NF1) maps to the pericentromeric region of chromosome 17 in Chinese families.
Volume: 10
Issue: 4
Pages: 1090-2
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Publication
10432316 | -
 
First Author: Osada S
Year: 1999
Journal: Biochem J
Title: Expression, DNA-binding specificity and transcriptional regulation of nuclear factor 1 family proteins from rat.
Volume: 342 ( Pt 1)
Pages: 189-98
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Publication
12590132 | -
First Author: Fukuda A
Year: 2003
Journal: J Biol Chem
Title: Alleviation of PC4-mediated transcriptional repression by the ERCC3 helicase activity of general transcription factor TFIIH.
Volume: 278
Issue: 17
Pages: 14827-31
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Protein Domain
IPR009044 | ssDNA-bd_transcriptional_reg
Type: Homologous_superfamily
Description: This superfamily represents a ssDNA-binding transcriptional regulator domain consisting of a helix-swapped dimer of beta(4)-alpha motifs. This domain is found as a C-terminal domain in the transcriptional co-activator PC4 (also known as P15; where it is a dimer of two separate motifs), and in the plant transcriptional regulator PBF-2 (where it is a single chain domain formed by a tandem repeat of two motifs).Transcriptional regulators play a critical role in controlling the level of transcription from specific genes in response to different stimuli. Members of this family of transcriptional regulators, which preferentially bind single-stranded DNA, include PBF-2 from plants, the mammalian nuclear factor 1-X (NF1-X), and positive cofactor 4 (PC4). These proteins are structurally similar, consisting of a helix-swapped dimer of beta(4)-alpha motifs.The plant defence transcription factor PBF-2 is comprised of four p24 subunits that interact through a helix-loop-helix motif to produce a central pore []. PBF-2 functions as part of the plant's defence system in response to the detection of a pathogen. Upon stimulation, PBF-2 induces several signal transduction pathways leading to changes in the expression of defence genes, including the pathogenesis-related (PR) genes.NF1-X is one of several NF1 proteins that function as transcription factors. NF1-X consists of two functionally distinct domains: a conserved N-terminal DNA-binding domain and a C-terminal transcriptional regulatory domain. NF1-X binds to the promoter for the 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase gene [].PC4 (or P15) possess the ability to co-activate and suppress transcription via its DNA-binding activity. PC4 has been shown to stimulate transcription in vitrowith diverse activators, including VP16, thyroid hormone receptor, BRCA-1, often involving TFIIA. PC4 and TFIIA are thought to facilitate the assembly of the pre-initiation complex. The repressive activity of PC4 can be alleviated by the transcription factor TFIIH, which protects promoters from PC4 repression []. PC4 consists of two domains: an N-terminal regulatory domain and a C-terminal cryptic DNA-binding domain. The protein acts as a dimer with two ssDNA binding channels running in opposite directions to each other [].
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Publication
10959417 | J:82305
 
First Author: Kane R
Year: 2000
Journal: Adv Exp Med Biol
Title: Transcription factor NF 1 expression in involuting mammary gland.
Volume: 480
Pages: 117-22
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Publication
16869751 | J:116750
 
First Author: Parada LF
Year: 2005
Journal: Cold Spring Harb Symp Quant Biol
Title: Modeling neurofibromatosis type 1 tumors in the mouse for therapeutic intervention.
Volume: 70
Pages: 173-6
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Publication
23424002 | J:316230
First Author: Pong WW
Year: 2013
Journal: Ann Neurol
Title: Reduced microglial CX3CR1 expression delays neurofibromatosis-1 glioma formation.
Volume: 73
Issue: 2
Pages: 303-8
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Publication
25877329 | J:223339
First Author: Ratner N
Year: 2015
Journal: Nat Rev Cancer
Title: A RASopathy gene commonly mutated in cancer: the neurofibromatosis type 1 tumour suppressor.
Volume: 15
Issue: 5
Pages: 290-301
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Nf1/Nf1 Tg(Tek-cre)1Ywa/?
Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1 Tg(Tek-cre)1Ywa/?
Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Egfr/Egfr<+> Nf1/Nf1<+> Trp53/Trp53<+>
Background: involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * C57BL/6JEi * C3H/HeSnJ
Zygosity: cx
Has Mutant Allele: true
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Publication
9360603 | -
First Author: Brandsen J
Year: 1997
Journal: Nat Struct Biol
Title: C-terminal domain of transcription cofactor PC4 reveals dimeric ssDNA binding site.
Volume: 4
Issue: 11
Pages: 900-3
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Publication
12080340 | -
First Author: Desveaux D
Year: 2002
Journal: Nat Struct Biol
Title: A new family of plant transcription factors displays a novel ssDNA-binding surface.
Volume: 9
Issue: 7
Pages: 512-7
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Publication
15767669 | J:97580
First Author: Chong JA
Year: 2005
Journal: Mol Cell Biol
Title: TATA-binding protein (TBP)-like factor (TLF) is a functional regulator of transcription: reciprocal regulation of the neurofibromatosis type 1 and c-fos genes by TLF/TRF2 and TBP.
Volume: 25
Issue: 7
Pages: 2632-43
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Publication
7890167 | J:23977
First Author: Raval P
Year: 1995
Journal: Gene
Title: Characterization of the 5' flanking region and gene encoding the mouse interferon-gamma receptor.
Volume: 154
Issue: 2
Pages: 219-23
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Publication
19515240 | J:151415
 
First Author: Pitulescu ME
Year: 2009
Journal: BMC Biochem
Title: TIPT2 and geminin interact with basal transcription factors to synergize in transcriptional regulation.
Volume: 10
Pages: 16
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Publication
25117714 | J:214594
First Author: Ozawa T
Year: 2014
Journal: Cancer Cell
Title: Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma.
Volume: 26
Issue: 2
Pages: 288-300
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Publication
31327527 | J:355240
First Author: Neftel C
Year: 2019
Journal: Cell
Title: An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma.
Volume: 178
Issue: 4
Pages: 835-849.e21
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Publication
25822087 | J:231792
First Author: Zhao Z
Year: 2015
Journal: Nat Genet
Title: Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis.
Volume: 47
Issue: 5
Pages: 539-43
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Publication
1505963 | J:1707
First Author: Legius E
Year: 1992
Journal: Genomics
Title: NF1-related locus on chromosome 15.
Volume: 13
Issue: 4
Pages: 1316-8
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Publication
17297459 | J:125503
First Author: Le LQ
Year: 2007
Journal: Oncogene
Title: Tumor microenvironment and neurofibromatosis type I: connecting the GAPs.
Volume: 26
Issue: 32
Pages: 4609-16
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Publication
21305617 | J:172839
First Author: Hambardzumyan D
Year: 2011
Journal: Glia
Title: Genetic modeling of gliomas in mice: new tools to tackle old problems.
Volume: 59
Issue: 8
Pages: 1155-68
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Publication
23055477 | J:190909
First Author: Gutmann DH
Year: 2012
Journal: J Neurosci
Title: Neurofibromatosis type 1: modeling CNS dysfunction.
Volume: 32
Issue: 41
Pages: 14087-93
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Publication
22898602 | J:191819
First Author: Ward AF
Year: 2012
Journal: Blood
Title: Targeting oncogenic Ras signaling in hematologic malignancies.
Volume: 120
Issue: 17
Pages: 3397-406
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Publication
26904939 | J:270438
First Author: Wu J
Year: 2016
Journal: Cell Rep
Title: Insertional Mutagenesis Identifies a STAT3/Arid1b/β-catenin Pathway Driving Neurofibroma Initiation.
Volume: 14
Issue: 8
Pages: 1979-90
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Publication
32461556 | J:292348
First Author: Lõhmussaar K
Year: 2020
Journal: Nat Commun
Title: Assessing the origin of high-grade serous ovarian cancer using CRISPR-modification of mouse organoids.
Volume: 11
Issue: 1
Pages: 2660
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Publication
35066574 | J:321223
First Author: Mo J
Year: 2022
Journal: Oncogene
Title: Neurofibromin and suppression of tumorigenesis: beyond the GAP.
Volume: 41
Issue: 9
Pages: 1235-1251
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Publication
39413183 | J:357534
First Author: Pundavela J
Year: 2024
Journal: Sci Adv
Title: Stimulator of interferon gene facilitates recruitment of effector CD8 T cells that drive neurofibromatosis type 1 nerve tumor initiation and maintenance.
Volume: 10
Issue: 42
Pages: eado6342
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Strain
MGI:5787928 | B6.Cg-Tg(Mx1-cre)1Cgn Nf1<tm1Fcr> Pten<tm1Hwu>
Attribute String: congenic, mutant strain, transgenic, targeted mutation
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Genotype
Genotype
Symbol: Nf1/Nf1 Trp53/Trp53 Tg(GFAP-cre)25Mes/?
Background: involves: 129S/SvEv * 129S4/SvJae * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nf1/Nf1<+> Pten/Pten Tg(Mx1-cre)1Cgn/?
Background: B6.Cg-Tg(Mx1-cre)1Cgn Nf1 Pten
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kitl/Kitl Nf1/Nf1
Background: involves: 129 * 129S/SvEv * C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Nf1/Nf1 Prss56/Prss56<+>
Background: involves: 129 * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Protein
P11031
Organism: Mus musculus/domesticus
Length: 127  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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