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Search results 801 to 900 out of 6883 for Pax6

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Type Details Score
Publication
17953485 | J:127119
First Author: Visel A
Year: 2007
Journal: PLoS Genet
Title: Regulatory pathway analysis by high-throughput in situ hybridization.
Volume: 3
Issue: 10
Pages: 1867-83
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Publication
10903178 | J:63215
First Author: Schwitzgebel VM
Year: 2000
Journal: Development
Title: Expression of neurogenin3 reveals an islet cell precursor population in the pancreas.
Volume: 127
Issue: 16
Pages: 3533-42
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Publication
30485816 | J:271140
First Author: Diacou R
Year: 2018
Journal: Cell Rep
Title: Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation.
Volume: 25
Issue: 9
Pages: 2510-2523.e4
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Publication
16102745 | J:101264
First Author: Smith AN
Year: 2005
Journal: Dev Biol
Title: The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm.
Volume: 285
Issue: 2
Pages: 477-89
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Publication
18077586 | J:130571
First Author: Pan Y
Year: 2008
Journal: Development
Title: Bud specific N-sulfation of heparan sulfate regulates Shp2-dependent FGF signaling during lacrimal gland induction.
Volume: 135
Issue: 2
Pages: 301-10
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Publication
23935957 | J:204946
First Author: Rodrigues PM
Year: 2013
Journal: PLoS One
Title: Nbn and atm cooperate in a tissue and developmental stage-specific manner to prevent double strand breaks and apoptosis in developing brain and eye.
Volume: 8
Issue: 7
Pages: e69209
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Publication
29025924 | J:250661
First Author: Muralidharan B
Year: 2017
Journal: J Neurosci
Title: Dmrt5, a Novel Neurogenic Factor, Reciprocally Regulates Lhx2 to Control the Neuron-Glia Cell-Fate Switch in the Developing Hippocampus.
Volume: 37
Issue: 46
Pages: 11245-11254
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HT Experiment
GSE45143 | Pax6 is required for normal cell cycle exit and the differentiation kinetics of retinal progenitor cells.
Series Id: E-GEOD-45143
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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Publication
22275127 | J:181272
First Author: Le TT
Year: 2012
Journal: Dev Dyn
Title: Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development.
Volume: 241
Issue: 3
Pages: 493-504
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Publication
27829154 | J:240973
First Author: Tao C
Year: 2016
Journal: Cell Rep
Title: Retinal Proteoglycans Act as Cellular Receptors for Basement Membrane Assembly to Control Astrocyte Migration and Angiogenesis.
Volume: 17
Issue: 7
Pages: 1832-1844
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Publication
8631154 | J:32853
First Author: Graw J
Year: 1996
Journal: Dev Genet
Title: Genetic aspects of embryonic eye development in vertebrates.
Volume: 18
Issue: 3
Pages: 181-97
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Publication
17410548 | J:121794
First Author: Kreslova J
Year: 2007
Journal: Genesis
Title: Abnormal lens morphogenesis and ectopic lens formation in the absence of beta-catenin function.
Volume: 45
Issue: 4
Pages: 157-68
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Publication
22258620 | J:181926
First Author: Jo HS
Year: 2012
Journal: EMBO J
Title: Pten coordinates retinal neurogenesis by regulating Notch signalling.
Volume: 31
Issue: 4
Pages: 817-28
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Publication
31668390 | J:292845
 
First Author: Piccand J
Year: 2019
Journal: Mol Metab
Title: Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production.
Volume: 29
Pages: 24-39
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Publication
29609731 | J:264149
   
First Author: Goto S
Year: 2018
Journal: Elife
Title: Neural retina-specific Aldh1a1 controls dorsal choroidal vascular development via Sox9 expression in retinal pigment epithelial cells.
Volume: 7
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Publication
25715397 | J:220323
First Author: Carpenter AC
Year: 2015
Journal: Development
Title: Wnt ligands from the embryonic surface ectoderm regulate 'bimetallic strip' optic cup morphogenesis in mouse.
Volume: 142
Issue: 5
Pages: 972-82
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Publication
24125957 | J:204690
First Author: Brzezinski JA 4th
Year: 2013
Journal: Dev Biol
Title: Blimp1 (Prdm1) prevents re-specification of photoreceptors into retinal bipolar cells by restricting competence.
Volume: 384
Issue: 2
Pages: 194-204
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Publication
30059908 | J:264269
 
First Author: Azimi M
Year: 2018
Journal: Differentiation
Title: Presenilin gene function and Notch signaling feedback regulation in the developing mouse lens.
Volume: 102
Pages: 40-52
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Publication
22745308 | J:185652
First Author: Qu X
Year: 2012
Journal: Development
Title: Glycosaminoglycan-dependent restriction of FGF diffusion is necessary for lacrimal gland development.
Volume: 139
Issue: 15
Pages: 2730-9
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Publication
23940571 | J:205763
First Author: Suissa Y
Year: 2013
Journal: PLoS One
Title: Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas.
Volume: 8
Issue: 8
Pages: e70397
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Publication
12624426 | J:126939
First Author: Herrera PL
Year: 2002
Journal: Endocrine
Title: Pancreatic cell lineage analyses in mice.
Volume: 19
Issue: 3
Pages: 267-78
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Publication
22884324 | J:188341
First Author: Chen WV
Year: 2012
Journal: Neuron
Title: Functional significance of isoform diversification in the protocadherin gamma gene cluster.
Volume: 75
Issue: 3
Pages: 402-9
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Publication
21888903 | J:178171
First Author: Magenheim J
Year: 2011
Journal: Dev Biol
Title: Ngn3(+) endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epithelium.
Volume: 359
Issue: 1
Pages: 26-36
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Publication
24284065 | J:310318
First Author: Li H
Year: 2014
Journal: J Cell Sci
Title: Frs2α and Shp2 signal independently of Gab to mediate FGF signaling in lens development.
Volume: 127
Issue: Pt 3
Pages: 571-82
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Publication
30188892 | J:266214
First Author: Garg A
Year: 2018
Journal: PLoS Genet
Title: FGF-induced Pea3 transcription factors program the genetic landscape for cell fate determination.
Volume: 14
Issue: 9
Pages: e1007660
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Publication
17428831 | J:121416
First Author: Song N
Year: 2007
Journal: Development
Title: pygopus 2 has a crucial, Wnt pathway-independent function in lens induction.
Volume: 134
Issue: 10
Pages: 1873-85
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Publication
36737666 | J:333797
First Author: Min KW
Year: 2023
Journal: Exp Mol Med
Title: Visuomotor anomalies in achiasmatic mice expressing a transfer-defective Vax1 mutant.
Volume: 55
Issue: 2
Pages: 385-400
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Publication
19906857 | J:154982
First Author: Yun S
Year: 2009
Journal: Development
Title: Lhx2 links the intrinsic and extrinsic factors that control optic cup formation.
Volume: 136
Issue: 23
Pages: 3895-906
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HT Experiment
E-MTAB-10262 | RNA-Seq analysis of E15.5 mouse Insm1, Neurod1 and Pax6 knockouts vs Insm1GFP.Cre/+ controls
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
25488119 | J:217375
 
First Author: Heavner WE
Year: 2014
Journal: Neural Dev
Title: Establishment of the neurogenic boundary of the mouse retina requires cooperation of SOX2 and WNT signaling.
Volume: 9
Pages: 27
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Protein Coding Gene
MGP_CAROLIEiJ_G0024037 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026230 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026191 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026171 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026200 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025950 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_97490 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026651 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025415 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025928 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026066 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026029 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026169 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026053 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026705 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025150 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025482 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025475 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0024950 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1612585 | J:886
First Author: Ton CC
Year: 1992
Journal: Genomics
Title: Small eye (Sey): cloning and characterization of the murine homolog of the human aniridia gene.
Volume: 13
Issue: 2
Pages: 251-6
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Publication
- | J:12101
First Author: Roberts RC
Year: 1967
Journal: Genet Res
Title: Small-eyes, a new dominant mutant in the mouse.
Volume: 9
Issue: 1
Pages: 121-122
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Publication
4972360 | J:5093
First Author: Clayton RM
Year: 1968
Journal: J Physiol
Title: Small eye, a mutant in the house mouse apparently affecting the synthesis of extracellular membranes.
Volume: 198
Issue: 2
Pages: 74passim-75p
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Publication
9853907 | J:51272
First Author: Dellovade TL
Year: 1998
Journal: J Comp Neurol
Title: Olfactory bulb development is altered in small-eye (Sey) mice.
Volume: 402
Issue: 3
Pages: 402-18
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Publication
37072572 | J:352535
First Author: Mirjalili Mohanna SZ
Year: 2023
Journal: Gene Ther
Title: rAAV-PHP.B escapes the mouse eye and causes lethality whereas rAAV9 can transduce aniridic corneal limbal stem cells without lethality.
Volume: 30
Issue: 9
Pages: 670-684
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Publication
10772788 | J:61929
First Author: Enwright JF 3rd
Year: 2000
Journal: Dev Biol
Title: Altered retinoid signaling in the heads of small eye mouse embryos.
Volume: 221
Issue: 1
Pages: 10-22
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Publication
4426343 | J:5495
First Author: Pritchard DJ
Year: 1974
Journal: Exp Eye Res
Title: Abnormal lens capsule carbohydrate associated with the dominant gene "small-eye" in the mouse.
Volume: 19
Issue: 4
Pages: 335-40
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Publication
7559133 | J:26774
 
First Author: Kaufman MH
Year: 1995
Journal: J Anat
Title: Craniofacial abnormalities in homozygous Small eye (Sey/Sey) embryos and newborn mice.
Volume: 186 ( Pt 3)
Pages: 607-17
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Publication
- | J:64257
 
First Author: Clayton RM
Year: 1968
Journal: Mouse News Lett
Title: Pax6Sey - small eye
Volume: 39
Pages: 22
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Publication
9733944 | J:50060
First Author: Brunjes PC
Year: 1998
Journal: Brain Res Dev Brain Res
Title: The small-eye mutation results in abnormalities in the lateral cortical migratory stream.
Volume: 110
Issue: 1
Pages: 121-5
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Publication
7649798 | J:22316
 
First Author: Dangata YY
Year: 1994
Journal: J Anat
Title: Morphometric study of the optic nerve of adult normal mice and mice heterozygous for the Small eye mutation (Sey/+).
Volume: 185 ( Pt 3)
Pages: 627-35
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Publication
- | J:14117
 
First Author: Hogan BL
Year: 1987
Journal: Mouse News Lett
Title: Allelism of small eyes (Sey) with Dickie's small eye (Dey) on Chromosome 2.
Volume: 77
Pages: 135-8
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Publication
8213068 | J:15471
First Author: Schmahl W
Year: 1993
Journal: Acta Neuropathol
Title: Defects of neuronal migration and the pathogenesis of cortical malformations are associated with Small eye (Sey) in the mouse, a point mutation at the Pax-6-locus.
Volume: 86
Issue: 2
Pages: 126-35
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Publication
- | J:14099
 
First Author: Davisson MT
Year: 1986
Journal: Mouse News Lett
Title: Position of Dey on Chr 2
Volume: 75
Pages: 30-31
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Publication
- | J:24775
 
First Author: Varnum D
Year: 1974
Journal: Mouse News Lett
Title: Dickie's small eye (Dey)
Volume: 50
Pages: 43
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Publication
3025741 | J:8543
First Author: Harbers K
Year: 1986
Journal: Nature
Title: High frequency of unequal recombination in pseudoautosomal region shown by proviral insertion in transgenic mouse.
Volume: 324
Issue: 6098
Pages: 682-5
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Publication
12714618 | J:83026
First Author: Ramaesh T
Year: 2003
Journal: Invest Ophthalmol Vis Sci
Title: Corneal abnormalities in Pax6+/- small eye mice mimic human aniridia-related keratopathy.
Volume: 44
Issue: 5
Pages: 1871-8
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Publication
10742717 | J:61341
First Author: Valverde F
Year: 2000
Journal: J Comp Neurol
Title: Development of the mammillothalamic tract in normal and Pax-6 mutant mice.
Volume: 419
Issue: 4
Pages: 485-504
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Publication
3352634 | J:177480
First Author: Favor J
Year: 1988
Journal: Mutat Res
Title: The effect of dose fractionation on the frequency of ethylnitrosourea-induced dominant cataract and recessive specific locus mutations in germ cells of the mouse.
Volume: 198
Issue: 2
Pages: 269-75
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Publication
9166583 | J:40665
First Author: Favor J
Year: 1997
Journal: Mamm Genome
Title: The mouse Cat4 locus maps to chromosome 8 and mutants express lens-corneal adhesion.
Volume: 8
Issue: 6
Pages: 403-6
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Publication
- | J:69257
 
First Author: Cattanach BM
Year: 1996
Journal: Mouse Genome
Title: Two Sey (Pax6) mutants
Volume: 94
Pages: 678
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Publication
23592925 | J:196657
 
First Author: Puk O
Year: 2013
Journal: Mol Vis
Title: Novel small-eye allele in paired box gene 6 (Pax6) is caused by a point mutation in intron 7 and creates a new exon.
Volume: 19
Pages: 877-84
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Publication
17660683 | J:124276
First Author: Nitta Y
Year: 2007
Journal: Exp Anim
Title: Intestinal tumorigenicity of mice carrying hemizygous Pax6, Pax6(Sey-4H).
Volume: 56
Issue: 4
Pages: 289-94
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Publication
11668672 | J:129691
First Author: Schaft J
Year: 2001
Journal: Genesis
Title: Efficient FLP recombination in mouse ES cells and oocytes.
Volume: 31
Issue: 1
Pages: 6-10
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Publication
15304967 | J:92585
First Author: Nitta Y
Year: 2004
Journal: J Radiat Res
Title: Spontaneous and radiation-induced leukemogenesis of the mouse small eye mutant, Pax6(Sey3H).
Volume: 45
Issue: 2
Pages: 245-51
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Publication
36029893 | J:340423
 
First Author: Mirjalili Mohanna SZ
Year: 2022
Journal: J Control Release
Title: LNP-mediated delivery of CRISPR RNP for wide-spread in vivo genome editing in mouse cornea.
Volume: 350
Pages: 401-413
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Publication
10885745 | J:62576
First Author: Sivak JM
Year: 2000
Journal: Dev Biol
Title: Pax-6 expression and activity are induced in the reepithelializing cornea and control activity of the transcriptional promoter for matrix metalloproteinase gelatinase B.
Volume: 222
Issue: 1
Pages: 41-54
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Publication
1684738 | J:33294
First Author: Ton CC
Year: 1991
Journal: Cell
Title: Positional cloning and characterization of a paired box- and homeobox-containing gene from the aniridia region.
Volume: 67
Issue: 6
Pages: 1059-74
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Publication
1352238 | J:50
First Author: Püschel AW
Year: 1992
Journal: Development
Title: Sequence and expression pattern of pax-6 are highly conserved between zebrafish and mice.
Volume: 114
Issue: 3
Pages: 643-51
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Publication
7914031 | J:19696
First Author: Quiring R
Year: 1994
Journal: Science
Title: Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans.
Volume: 265
Issue: 5173
Pages: 785-9
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Publication
7981749 | J:15670
First Author: Matsuo T
Year: 1993
Journal: Nat Genet
Title: A mutation in the Pax-6 gene in rat small eye is associated with impaired migration of midbrain crest cells.
Volume: 3
Issue: 4
Pages: 299-304
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Publication
8661719 | J:33162
First Author: Elango R
Year: 1996
Journal: Mamm Genome
Title: Generation and mapping of Mus spretus strain-specific markers for rapid genomic scanning.
Volume: 7
Issue: 5
Pages: 340-3
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Publication
8760335 | J:34981
First Author: Cvekl A
Year: 1996
Journal: Bioessays
Title: Lens development and crystallin gene expression: many roles for Pax-6.
Volume: 18
Issue: 8
Pages: 621-30
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Publication
9122153 | J:39393
First Author: Harris WA
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Pax-6: where to be conserved is not conservative.
Volume: 94
Issue: 6
Pages: 2098-100
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Publication
9247338 | J:42530
First Author: Osumi N
Year: 1997
Journal: Development
Title: Pax-6 is involved in the specification of hindbrain motor neuron subtype.
Volume: 124
Issue: 15
Pages: 2961-72
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Publication
9622640 | J:48132
First Author: Williams SC
Year: 1998
Journal: Mech Dev
Title: A highly conserved lens transcriptional control element from the Pax-6 gene.
Volume: 73
Issue: 2
Pages: 225-9
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Publication
10461206 | J:57033
First Author: Gehring WJ
Year: 1999
Journal: Trends Genet
Title: Pax 6: mastering eye morphogenesis and eye evolution.
Volume: 15
Issue: 9
Pages: 371-7
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Publication
21500284 | J:171652
First Author: Joly S
Year: 2011
Journal: Glia
Title: Pax6-positive Müller glia cells express cell cycle markers but do not proliferate after photoreceptor injury in the mouse retina.
Volume: 59
Issue: 7
Pages: 1033-46
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GXD Expression
GXD Expression
     
Probe: MGI:2156735
Assay Type: Western blot
Annotation Date: 2002-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185823
Stage: TS23
Assay Id: MGI:2156860
Age: embryonic day 15.0
Specimen Label: 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2156735
Assay Type: Western blot
Annotation Date: 2002-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185823
Stage: TS23
Assay Id: MGI:2156860
Age: embryonic day 15.0
Specimen Label: 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2156735
Assay Type: Western blot
Annotation Date: 2002-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185823
Stage: TS23
Assay Id: MGI:2156860
Age: embryonic day 15.0
Specimen Label: 3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2156735
Assay Type: Western blot
Annotation Date: 2002-01-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3185823
Stage: TS23
Assay Id: MGI:2156860
Age: embryonic day 15.0
Specimen Label: 4
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:2159158
Assay Type: RT-PCR
Annotation Date: 2002-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619817
Stage: TS17
Assay Id: MGI:2159267
Age: embryonic day 10.5
Image: 1
Specimen Label: E10.5 Eye RNA
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:2179315
Assay Type: RT-PCR
Annotation Date: 2002-05-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:2179385
Age: embryonic day 10.5
Image: 6
Specimen Label: 10.5 dpc
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:2157328
Assay Type: Western blot
Annotation Date: 2004-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185821
Stage: TS21
Assay Id: MGI:2683430
Age: embryonic day 13.0
Image: 5
Specimen Label: control
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:2686868
Assay Type: RT-PCR
Annotation Date: 2004-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706619
Stage: TS19
Assay Id: MGI:2686871
Age: embryonic day 11.5-12.0
Specimen Label: Embryonic 2/6
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:2686868
Assay Type: RT-PCR
Annotation Date: 2004-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:2686871
Age: postnatal adult
Specimen Label: Adult 2/6
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:2686868
Assay Type: RT-PCR
Annotation Date: 2004-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292728
Stage: TS28
Assay Id: MGI:2686871
Age: postnatal adult
Specimen Label: Adult Islets
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:2686868
Assay Type: RT-PCR
Annotation Date: 2004-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:2686871
Age: postnatal adult
Specimen Label: Adult Eye
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:2686868
Assay Type: RT-PCR
Annotation Date: 2004-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:2686871
Age: postnatal adult
Specimen Label: Adult Cerebellum
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:2686869
Assay Type: RT-PCR
Annotation Date: 2004-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706619
Stage: TS19
Assay Id: MGI:2686872
Age: embryonic day 11.5-12.0
Specimen Label: Embryonic 6/13
Detected: true
Specimen Num: 2
•
•
•
•
•




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