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Search results 801 to 900 out of 1030 for Pax8

0.023s
Type Details Score
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Laszczyk AM
Year: 2020
Journal: J Am Soc Nephrol
Title: Pax2 and Pax8 Proteins Regulate Urea Transporters and Aquaporins to Control Urine Concentration in the Adult Kidney.
Volume: 31
Issue: 6
Pages: 1212-1225
Publication  
First Author: Drews C
Year: 2011
Journal: BMC Dev Biol
Title: The nephrogenic potential of the transcription factors osr1, osr2, hnf1b, lhx1 and pax8 assessed in Xenopus animal caps.
Volume: 11
Pages: 5
Publication
First Author: Meeus L
Year: 2004
Journal: J Clin Endocrinol Metab
Title: Characterization of a novel loss of function mutation of PAX8 in a familial case of congenital hypothyroidism with in-place, normal-sized thyroid.
Volume: 89
Issue: 9
Pages: 4285-91
DO Term
GXD Expression
Probe: MGI:3577967
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-05
Strength: Present
Sex: Male
Emaps: EMAPS:2909822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6514880
Age: embryonic day 14.5
Image: 8A left
Note: Amh-positive cells were found co-expressing Pax8 at the mesonephric border of the testis at E14.5. These cells were also found to express Sox9.
Specimen Label: 8A left
Detected: true
Specimen Num: 21
GXD Expression
Probe: MGI:6382565
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-06
Strength: Present
Sex: Female
Emaps: EMAPS:2892921
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6515597
Age: embryonic day 13.5
Image: 9C lower
Note: Foxl2-positive cells that co-expressed Sox9 and Pax8 were found in the part of the rete ovarii adjacent to the gonad tissue.
Specimen Label: 9C lower
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:3577967
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-05
Strength: Present
Sex: Male
Emaps: EMAPS:1868524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6514880
Age: embryonic day 16.5
Image: 8C left
Note: Amh-positive cells were found co-expressing Pax8 at the border between testis cords and the rete testis at E16.5. These cells were also found to express Sox9.
Specimen Label: 8C left
Detected: true
Specimen Num: 25
Allele
Name: paired box 8; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inserted expressed sequence
Allele
Name: paired box 8; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Recombinase
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Protein Domain
Type: Family
Description: This entry represents the PDZK1-interacting protein 1 (PDZK1IP1) family. Members include PDZK1IP1 and proximal tubules-expressed gene protein (also known as PDZK1-interacting protein 1-like andMAP17).The function of PDZK1IP1 is unknown. However, it has been found diffusely expressed in various carcinomas originating from kidney, colon, lung and breast in humans [].Proximal tubules-expressed gene protein, meanwhile, has been shown to be essential for pronephric tubule development, acting upstream of pax8 and lhx1/lim1 and downstream of retinoic acid signaling to induce pronephric mesoderm to form pronephric tubule-specific cells [].
Allele
Name: transgene insertion 1, Ronald J Koenig
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: paired box 3; targeted mutation 6, Margaret E Buckingham
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Null/knockout, Reporter
Publication
First Author: Traykova-Brauch M
Year: 2008
Journal: Nat Med
Title: An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice.
Volume: 14
Issue: 9
Pages: 979-84
Publication
First Author: Faresse N
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Inducible kidney-specific Sgk1 knockout mice show a salt-losing phenotype.
Volume: 302
Issue: 8
Pages: F977-85
Publication
First Author: Zhang S
Year: 2019
Journal: Nat Commun
Title: Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma.
Volume: 10
Issue: 1
Pages: 5367
Protein
Organism: Mus musculus/domesticus
Length: 114  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 181  
Fragment?: false
Publication
First Author: Kocher O
Year: 1998
Journal: Lab Invest
Title: Identification and partial characterization of PDZK1: a novel protein containing PDZ interaction domains.
Volume: 78
Issue: 1
Pages: 117-25
Publication
First Author: Lee SJ
Year: 2010
Journal: Mech Dev
Title: XPteg (Xenopus proximal tubules-expressed gene) is essential for pronephric mesoderm specification and tubulogenesis.
Volume: 127
Issue: 1-2
Pages: 49-61
Publication
First Author: Espana-Agusti J
Year: 2016
Journal: PLoS One
Title: Generation and Characterisation of a Pax8-CreERT2 Transgenic Line and a Slc22a6-CreERT2 Knock-In Line for Inducible and Specific Genetic Manipulation of Renal Tubular Epithelial Cells.
Volume: 11
Issue: 2
Pages: e0148055
Allele
Name: paired box 8; targeted mutation 1.1, Meinrad Busslinger
Allele Type: Targeted
Attribute String: Recombinase
Strain
Attribute String: targeted mutation, mutant strain, congenic
Allele
Name: transgene insertion 1, Robert Koesters
Allele Type: Transgenic
Attribute String: Transactivator
Strain
Attribute String: mutant stock, transgenic
Strain
Attribute String: congenic, transgenic
Strain
Attribute String: transgenic, mutant strain, congenic
Publication
First Author: Singh S
Year: 2016
Journal: PLoS One
Title: Tubular Overexpression of Angiopoietin-1 Attenuates Renal Fibrosis.
Volume: 11
Issue: 7
Pages: e0158908
Allele
Name: transgene insertion C, Athena Matakidou
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Genotype
Symbol: Pax3/Pax3<+>
Background: involves: 129S2/SvPas
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Pax3/Pax3
Background: involves: 129S2/SvPas
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Pax8/Pax8
Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Zygosity: hm
Has Mutant Allele: true
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Publication  
First Author: Miguel V
Year: 2023
Journal: Redox Biol
Title: Enhanced fatty acid oxidation through metformin and baicalin as therapy for COVID-19 and associated inflammatory states in lung and kidney.
Volume: 68
Pages: 102957
Publication  
First Author: Miguel V
Year: 2021
Journal: J Clin Invest
Title: Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis.
Volume: 131
Issue: 5
Allele
Name: transgene insertion 1, Andrew P McMahon
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: coisogenic, mutant strain, transgenic
Genotype
Symbol: Ugcg/Ugcg Pax8/Pax8<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pax8/Pax8<+> Plxnb2/Plxnb2
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hnrnpf/Hnrnpf Pax8/Pax8<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Glis3/Glis3 Pax8/Pax8<+>
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Stuart ET
Year: 1995
Journal: EMBO J
Title: Loss of p53 function through PAX-mediated transcriptional repression.
Volume: 14
Issue: 22
Pages: 5638-45
Publication
First Author: Lòpez-Corrales NL
Year: 1999
Journal: Cytogenet Cell Genet
Title: Physical mapping of the bovine, caprine and ovine homologues of the paired box gene PAX8.
Volume: 84
Issue: 3-4
Pages: 179-81
Publication
First Author: Sinha S
Year: 2020
Journal: FASEB J
Title: Glycogen synthase kinase-3β inhibits tubular regeneration in acute kidney injury by a FoxM1-dependent mechanism.
Volume: 34
Issue: 10
Pages: 13597-13608
Publication
First Author: Yakulov TA
Year: 2018
Journal: Nat Commun
Title: CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury.
Volume: 9
Issue: 1
Pages: 3660
Publication
First Author: Yuan Q
Year: 2021
Journal: Cell Death Dis
Title: CPT1α maintains phenotype of tubules via mitochondrial respiration during kidney injury and repair.
Volume: 12
Issue: 8
Pages: 792
Strain
Attribute String: congenic, mutant strain, targeted mutation
Publication
First Author: Friedrich S
Year: 2021
Journal: Sci Rep
Title: Identification of pathological transcription in autosomal dominant polycystic kidney disease epithelia.
Volume: 11
Issue: 1
Pages: 15139
Publication
First Author: Kang HM
Year: 2015
Journal: Nat Med
Title: Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development.
Volume: 21
Issue: 1
Pages: 37-46
Strain
Attribute String: transgenic, mutant stock
Genotype
Symbol: Tg(Pax8-rtTA2S*M2)1Koes/? Tg(tetO-MYC)36aBop/?
Background: involves: C57BL/6 * DBA * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Dkk1/Dkk1 Pax8/Pax8<+>
Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-EGFP,-PAX8/PPARG)1Rkoe/? Tg(TPO-cre)1Shk/?
Background: involves: FVB/NCr * FVB/NJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pax8/Pax8
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gal3st1/Gal3st1 Pax8/Pax8<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pax8/Pax8
Background: B6.129(Cg)-Pax8 Pax8
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pax8/Pax8<+> Plxnb1/Plxnb1 Plxnb2/Plxnb2
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pax8/Pax8<+> Pbrm1/Pbrm1
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Publication  
First Author: Nizar JM
Year: 2018
Journal: JCI Insight
Title: Renal tubule insulin receptor modestly promotes elevated blood pressure and markedly stimulates glucose reabsorption.
Volume: 3
Issue: 16
Publication
First Author: Terker AS
Year: 2016
Journal: J Am Soc Nephrol
Title: Direct and Indirect Mineralocorticoid Effects Determine Distal Salt Transport.
Volume: 27
Issue: 8
Pages: 2436-45
Publication
First Author: Haykir B
Year: 2024
Journal: J Am Soc Nephrol
Title: The Ip6k1 and Ip6k2 Kinases Are Critical for Normal Renal Tubular Function.
Volume: 35
Issue: 4
Pages: 441-455
Publication
First Author: Hu C
Year: 2022
Journal: Am J Physiol Renal Physiol
Title: Multiomic identification of factors associated with progression to cystic kidney disease in mice with nephron Ift88 disruption.
Volume: 322
Issue: 2
Pages: F175-F192
Publication
First Author: Trepiccione F
Year: 2016
Journal: J Am Soc Nephrol
Title: Renal Atp6ap2/(Pro)renin Receptor Is Required for Normal Vacuolar H+-ATPase Function but Not for the Renin-Angiotensin System.
Volume: 27
Issue: 11
Pages: 3320-3330
Publication
First Author: Hu C
Year: 2021
Journal: J Am Soc Nephrol
Title: Sex-Dependent Effects of Nephron Ift88 Disruption on BP, Renal Function, and Cystogenesis.
Volume: 32
Issue: 9
Pages: 2210-2222
Publication
First Author: Figueiredo M
Year: 2021
Journal: Pflugers Arch
Title: The (pro)renin receptor (ATP6ap2) facilitates receptor-mediated endocytosis and lysosomal function in the renal proximal tubule.
Volume: 473
Issue: 8
Pages: 1229-1246
Publication
First Author: Hu C
Year: 2022
Journal: Physiol Rep
Title: Profiling renal sodium transporters in mice with nephron Ift88 disruption: Association with sex, cysts, and blood pressure.
Volume: 10
Issue: 5
Pages: e15206
Publication
First Author: Saritas T
Year: 2019
Journal: Sci Rep
Title: Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis.
Volume: 9
Issue: 1
Pages: 4596
Publication
First Author: Grahammer F
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress.
Volume: 111
Issue: 27
Pages: E2817-26
Publication
First Author: Yanda MK
Year: 2018
Journal: J Biol Chem
Title: A potential strategy for reducing cysts in autosomal dominant polycystic kidney disease with a CFTR corrector.
Volume: 293
Issue: 29
Pages: 11513-11526
Publication
First Author: Yanda MK
Year: 2017
Journal: J Biol Chem
Title: Histone deacetylase 6 inhibition reduces cysts by decreasing cAMP and Ca2+ in knock-out mouse models of polycystic kidney disease.
Volume: 292
Issue: 43
Pages: 17897-17908
Publication
First Author: Yanda MK
Year: 2019
Journal: J Biol Chem
Title: Pharmacological reversal of renal cysts from secretion to absorption suggests a potential therapeutic strategy for managing autosomal dominant polycystic kidney disease.
Volume: 294
Issue: 45
Pages: 17090-17104
Publication
First Author: Yanda MK
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: An inhibitor of histone deacetylase 6 activity, ACY-1215, reduces cAMP and cyst growth in polycystic kidney disease.
Volume: 313
Issue: 4
Pages: F997-F1004
Publication    
First Author: Liu X
Year: 2018
Journal: Elife
Title: Polycystin-2 is an essential ion channel subunit in the primary cilium of the renal collecting duct epithelium.
Volume: 7
Publication
First Author: Tran MT
Year: 2016
Journal: Nature
Title: PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection.
Volume: 531
Issue: 7595
Pages: 528-32
Publication
First Author: Hakroush S
Year: 2009
Journal: Am J Pathol
Title: Effects of increased renal tubular vascular endothelial growth factor (VEGF) on fibrosis, cyst formation, and glomerular disease.
Volume: 175
Issue: 5
Pages: 1883-95
Publication
First Author: Ryu DR
Year: 2019
Journal: Aging Cell
Title: Sirt1-hypoxia-inducible factor-1α interaction is a key mediator of tubulointerstitial damage in the aged kidney.
Volume: 18
Issue: 2
Pages: e12904
Publication
First Author: Lan R
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: PTEN loss defines a TGF-β-induced tubule phenotype of failed differentiation and JNK signaling during renal fibrosis.
Volume: 302
Issue: 9
Pages: F1210-23
Publication
First Author: Han SH
Year: 2017
Journal: J Am Soc Nephrol
Title: PGC-1α Protects from Notch-Induced Kidney Fibrosis Development.
Volume: 28
Issue: 11
Pages: 3312-3322
Genotype
Symbol: Tg(Pax8-rtTA2S*M2)1Koes/? Tg(tetO-TGFB1*C223S*C225S)1Glk/?
Background: involves: C57BL/6 * DBA
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Gal3st1/Gal3st1 Ugcg/Ugcg Pax8/Pax8<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dicer1/Dicer1 Pax8/Pax8<+>
Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdc42/Cdc42 Tg(Pax8-rtTA2S*M2)1Koes/? Tg(tetO-cre)LC1Bjd/?
Background: involves: BALB/c * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true