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Search results 801 to 900 out of 941 for Prkca

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Type Details Score
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Gene
Type: gene
Organism: frog, African clawed
Gene
Type: gene
Organism: frog, African clawed
Allele
Name: protein kinase C, alpha; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
GXD Expression
Probe: MGI:4882095
Assay Type: In situ reporter (knock in)
Annotation Date: 2020-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6450171
Age: postnatal month 2-3
Image: 3Q
Note: Irx6:beta-gal positive bipolar cells did not co-label with Prkca immunopositive rod bipolar cells.
Specimen Label: 3Q
Detected: true
Specimen Num: 8
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
GXD Expression
Probe: MGI:6863894
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3574428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6863925
Age: postnatal week 8-12
Image: 5B
Note: Expression in rod bipolar cells, with ~90% of fiber-like expression colocalized with PKCalpha (Prkca) in axons. Expression also in fibers negative fo Prkca expression, likely cone bipolar cells.
Specimen Label: 5B
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6863894
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3574128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6863925
Age: postnatal week 8-12
Image: 5B
Note: Expression in rod bipolar cells, with ~90% of fiber-like expression colocalized with PKCalpha (Prkca) in axons. Expression also in fibers negative fo Prkca expression, likely cone bipolar cells.
Specimen Label: 5B
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6863894
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6863925
Age: postnatal week 8-12
Image: 5B
Note: Expression in rod bipolar cells, with ~90% of fiber-like expression colocalized with PKCalpha (Prkca) in axons. Expression also in fibers negative fo Prkca expression, likely cone bipolar cells.
Specimen Label: 5B
Detected: true
Specimen Num: 2
Allele
Name: protein kinase C, alpha; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Allele
Name: transgene insertion 1, Stuart H Yuspa
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Jeffery D Molkentin
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Cataisson C
Year: 2006
Journal: J Clin Invest
Title: CXCR2 ligands and G-CSF mediate PKCalpha-induced intraepidermal inflammation.
Volume: 116
Issue: 10
Pages: 2757-66
Strain
Attribute String: transgenic, mutant stock
Allele
Name: transgene insertion 1, Jeffery D Molkentin
Allele Type: Transgenic
Attribute String: Dominant negative, Inducible, Inserted expressed sequence
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Genotype
Symbol: Tg(Myh6-Prkca)1Jmk/?
Background: involves: FVB
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Latos-Bielenska A
Year: 1991
Journal: Hereditas
Title: Refinement of localization of the human genes for myeloperoxidase (MPO), protein kinase C, alpha polypeptide, PRKCA, and the DNA fragment D17S21 on chromosome 17q.
Volume: 115
Issue: 1
Pages: 69-72
Publication
First Author: Cataisson C
Year: 2009
Journal: Cancer Res
Title: Inducible cutaneous inflammation reveals a protumorigenic role for keratinocyte CXCR2 in skin carcinogenesis.
Volume: 69
Issue: 1
Pages: 319-28
Allele
Name: transgene insertion 115, Ajit K Verma
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: transgenic, mutant strain, coisogenic
Publication
First Author: Cataisson C
Year: 2016
Journal: Sci Signal
Title: MET signaling in keratinocytes activates EGFR and initiates squamous carcinogenesis.
Volume: 9
Issue: 433
Pages: ra62
Genotype
Symbol: Tg(Myh6-tTA)55Rbns/? Tg(Myh6/tetO-PRKCA*)1Jmk/?
Background: involves: FVB/N
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Woods SM
Year: 2018
Journal: Sci Rep
Title: A comparative analysis of rod bipolar cell transcriptomes identifies novel genes implicated in night vision.
Volume: 8
Issue: 1
Pages: 5506
Publication  
First Author: Barendse W
Year: 1991
Journal: Cytogenet Cell Genet
Title: Comparison of gene order of three bovine chromosomal segments to the human
Volume: 58
Pages: 2123 (Abstr.)
Publication
First Author: Polusani SR
Year: 2019
Journal: Cancer Res
Title: Adipokines Deregulate Cellular Communication via Epigenetic Repression of Gap Junction Loci in Obese Endometrial Cancer.
Volume: 79
Issue: 1
Pages: 196-208
Publication
First Author: Aziz MH
Year: 2006
Journal: Cancer Res
Title: Protein kinase C delta overexpressing transgenic mice are resistant to chemically but not to UV radiation-induced development of squamous cell carcinomas: a possible link to specific cytokines and cyclooxygenase-2.
Volume: 66
Issue: 2
Pages: 713-22
Publication  
First Author: Wiemann S
Year: 2021
Journal: Front Neurosci
Title: Knock-Out of Tenascin-C Ameliorates Ischemia-Induced Rod-Photoreceptor Degeneration and Retinal Dysfunction.
Volume: 15
Pages: 642176
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Staudinger J
Year: 1997
Journal: J Biol Chem
Title: Specific interaction of the PDZ domain protein PICK1 with the COOH terminus of protein kinase C-alpha.
Volume: 272
Issue: 51
Pages: 32019-24
Publication
First Author: Clem RL
Year: 2010
Journal: J Neurosci
Title: PICK1 regulates incorporation of calcium-permeable AMPA receptors during cortical synaptic strengthening.
Volume: 30
Issue: 18
Pages: 6360-6
Publication
First Author: Takeya R
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Interaction of the PDZ domain of human PICK1 with class I ADP-ribosylation factors.
Volume: 267
Issue: 1
Pages: 149-55
Publication
First Author: Xiao N
Year: 2009
Journal: J Clin Invest
Title: PICK1 deficiency causes male infertility in mice by disrupting acrosome formation.
Volume: 119
Issue: 4
Pages: 802-12
Publication
First Author: Backe MB
Year: 2023
Journal: J Endocr Soc
Title: PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity.
Volume: 7
Issue: 6
Pages: bvad057
Publication
First Author: Li J
Year: 2018
Journal: Mol Biol Cell
Title: PICK1 is essential for insulin production and the maintenance of glucose homeostasis.
Volume: 29
Issue: 5
Pages: 587-596
Publication
First Author: Anggono V
Year: 2011
Journal: J Neurosci
Title: PICK1 loss of function occludes homeostatic synaptic scaling.
Volume: 31
Issue: 6
Pages: 2188-96
Publication
First Author: Holst B
Year: 2013
Journal: PLoS Biol
Title: PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance.
Volume: 11
Issue: 4
Pages: e1001542
Publication
First Author: Volk L
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Developmental regulation of protein interacting with C kinase 1 (PICK1) function in hippocampal synaptic plasticity and learning.
Volume: 107
Issue: 50
Pages: 21784-9
Publication
First Author: Lin EYS
Year: 2018
Journal: Sci Rep
Title: Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction.
Volume: 8
Issue: 1
Pages: 13438
Publication
First Author: Wang YN
Year: 2015
Journal: J Neurosci
Title: Protein Interacting with C-Kinase 1 Deficiency Impairs Glutathione Synthesis and Increases Oxidative Stress via Reduction of Surface Excitatory Amino Acid Carrier 1.
Volume: 35
Issue: 16
Pages: 6429-43
Publication
First Author: Pinheiro PS
Year: 2014
Journal: J Neurosci
Title: The BAR domain protein PICK1 controls vesicle number and size in adrenal chromaffin cells.
Volume: 34
Issue: 32
Pages: 10688-700
Publication
First Author: Terashima A
Year: 2008
Journal: Neuron
Title: An essential role for PICK1 in NMDA receptor-dependent bidirectional synaptic plasticity.
Volume: 57
Issue: 6
Pages: 872-82
Publication
First Author: Hu ZL
Year: 2010
Journal: Am J Physiol Cell Physiol
Title: Disruption of PICK1 attenuates the function of ASICs and PKC regulation of ASICs.
Volume: 299
Issue: 6
Pages: C1355-62
Publication  
First Author: Li X
Year: 2013
Journal: Sci Rep
Title: Rescuing infertility of Pick1 knockout mice by generating testis-specific transgenic mice via testicular infection.
Volume: 3
Pages: 2842
Publication
First Author: Clem RL
Year: 2013
Journal: J Neurosci
Title: Norepinephrine enhances a discrete form of long-term depression during fear memory storage.
Volume: 33
Issue: 29
Pages: 11825-32
Publication
First Author: Alfonso S
Year: 2014
Journal: Eur J Neurosci
Title: Synapto-depressive effects of amyloid beta require PICK1.
Volume: 39
Issue: 7
Pages: 1225-33
Publication
First Author: Lin WJ
Year: 2001
Journal: Biochem J
Title: Mitogen-stimulated TIS21 protein interacts with a protein-kinase-Calpha-binding protein rPICK1.
Volume: 354
Issue: Pt 3
Pages: 635-43
Publication
First Author: Hanley JG
Year: 2002
Journal: Neuron
Title: NSF ATPase and alpha-/beta-SNAPs disassemble the AMPA receptor-PICK1 complex.
Volume: 34
Issue: 1
Pages: 53-67
Publication
First Author: Höhne M
Year: 2011
Journal: Mol Cell Biol
Title: The BAR domain protein PICK1 regulates cell recognition and morphogenesis by interacting with Neph proteins.
Volume: 31
Issue: 16
Pages: 3241-51
GXD Expression      
Probe: MGI:3811803
Assay Type: Western blot
Annotation Date: 2008-10-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689420
Stage: TS20
Assay Id: MGI:3811807
Age: embryonic day 12.0
Specimen Label: E12
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3811803
Assay Type: Western blot
Annotation Date: 2008-10-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:3811807
Age: embryonic day 14.0
Specimen Label: E14
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3811803
Assay Type: Western blot
Annotation Date: 2008-10-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:3811807
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3811803
Assay Type: Western blot
Annotation Date: 2008-10-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3811807
Age: embryonic day 19.0
Specimen Label: E19
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3811803
Assay Type: Western blot
Annotation Date: 2008-10-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3811807
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3811803
Assay Type: Western blot
Annotation Date: 2008-10-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3811807
Age: postnatal day 3
Specimen Label: P3
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3811803
Assay Type: Western blot
Annotation Date: 2008-10-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3811807
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3811803
Assay Type: Western blot
Annotation Date: 2008-10-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3811807
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3811803
Assay Type: Western blot
Annotation Date: 2008-10-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3811810
Age: postnatal day 7
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3811803
Assay Type: Western blot
Annotation Date: 2008-10-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3811810
Age: postnatal day 7
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3811803
Assay Type: Western blot
Annotation Date: 2008-10-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3811810
Age: postnatal day 7
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:3811803
Assay Type: Western blot
Annotation Date: 2008-10-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3811810
Age: postnatal week 8
Specimen Label: +/+
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3811803
Assay Type: Western blot
Annotation Date: 2008-10-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3811810
Age: postnatal week 8
Specimen Label: +/-
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3811803
Assay Type: Western blot
Annotation Date: 2008-10-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3811810
Age: postnatal week 8
Specimen Label: -/-
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:6831105
Assay Type: Western blot
Annotation Date: 2021-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:6831203
Age: embryonic day 15.0
Image: 3
Specimen Label: E15
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6831105
Assay Type: Western blot
Annotation Date: 2021-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6831203
Age: embryonic day 18.0
Image: 3
Specimen Label: E18
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6831105
Assay Type: Western blot
Annotation Date: 2021-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:6831203
Age: postnatal day 0
Image: 3
Specimen Label: P0
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6831105
Assay Type: Western blot
Annotation Date: 2021-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:6831203
Age: postnatal day 2
Image: 3
Specimen Label: P2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6831105
Assay Type: Western blot
Annotation Date: 2021-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6831203
Age: postnatal day 4
Image: 3
Specimen Label: P4
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6831105
Assay Type: Western blot
Annotation Date: 2021-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6831203
Age: postnatal day 6
Image: 3
Specimen Label: P6
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6831105
Assay Type: Western blot
Annotation Date: 2021-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6831203
Age: postnatal day 8
Image: 3
Specimen Label: P8
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6831105
Assay Type: Western blot
Annotation Date: 2021-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6831203
Age: postnatal day 10
Image: 3
Specimen Label: P10
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:6831105
Assay Type: Western blot
Annotation Date: 2021-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6831203
Age: postnatal day 12
Image: 3
Specimen Label: P12
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:6831105
Assay Type: Western blot
Annotation Date: 2021-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6831203
Age: postnatal day 14
Image: 3
Specimen Label: P14
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:6831105
Assay Type: Western blot
Annotation Date: 2021-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6831203
Age: postnatal day 28
Image: 3
Specimen Label: P28
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:6831105
Assay Type: Western blot
Annotation Date: 2021-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6831203
Age: postnatal day 90
Image: 3
Specimen Label: P90
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:4417073
Assay Type: RNA in situ
Annotation Date: 2023-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7530796
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6831103
Assay Type: Immunohistochemistry
Annotation Date: 2021-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6831210
Age: postnatal adult
Image: 3D
Note: Expressed in the dendrites of Purkinje neurons.
Specimen Label: 3D
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6831103
Assay Type: Immunohistochemistry
Annotation Date: 2021-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6831206
Age: postnatal adult
Image: 3C
Note: Expressed in the dendrites of Purkinje neurons.
Specimen Label: 3C
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6831103
Assay Type: Immunohistochemistry
Annotation Date: 2021-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6831210
Age: postnatal adult
Image: 3D
Note: Highest expression. Expressed in the perinuclear region.
Specimen Label: 3D
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6831103
Assay Type: Immunohistochemistry
Annotation Date: 2021-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6831206
Age: postnatal adult
Image: 3C
Note: Highest expression. Expressed in the perinuclear region.
Specimen Label: 3C
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4417073
Assay Type: RNA in situ
Annotation Date: 2023-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7530796
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1