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Search results 801 to 900 out of 1222 for Ptf1a

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Type Details Score
Publication
26257060 | J:233987
First Author: Taki K
Year: 2016
Journal: Oncogene
Title: GNAS(R201H) and Kras(G12D) cooperate to promote murine pancreatic tumorigenesis recapitulating human intraductal papillary mucinous neoplasm.
Volume: 35
Issue: 18
Pages: 2407-12
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Publication
28057752 | J:241086
First Author: Xiao X
Year: 2017
Journal: J Biol Chem
Title: Forkhead Box Protein 1 (FoxO1) Inhibits Accelerated β Cell Aging in Pancreas-specific SMAD7 Mutant Mice.
Volume: 292
Issue: 8
Pages: 3456-3465
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Publication
24395249 | J:205582
First Author: Saborowski M
Year: 2014
Journal: Genes Dev
Title: A modular and flexible ESC-based mouse model of pancreatic cancer.
Volume: 28
Issue: 1
Pages: 85-97
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Publication
25906749 | J:264409
First Author: Mohammed A
Year: 2015
Journal: Oncotarget
Title: Targeting pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression.
Volume: 6
Issue: 17
Pages: 15524-39
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Publication
30954952 | J:285559
First Author: Benitz S
Year: 2019
Journal: Gut
Title: Ring1b-dependent epigenetic remodelling is an essential prerequisite for pancreatic carcinogenesis.
Volume: 68
Issue: 11
Pages: 2007-2018
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Publication
33388318 | J:314686
First Author: Zhao Y
Year: 2021
Journal: Gastroenterology
Title: mTORC1 and mTORC2 Converge on the Arp2/3 Complex to Promote KrasG12D-Induced Acinar-to-Ductal Metaplasia and Early Pancreatic Carcinogenesis.
Volume: 160
Issue: 5
Pages: 1755-1770.e17
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Publication
29384525 | J:267927
First Author: Hassan Z
Year: 2018
Journal: Br J Cancer
Title: MTOR inhibitor-based combination therapies for pancreatic cancer.
Volume: 118
Issue: 3
Pages: 366-377
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Publication
33983114 | J:314151
   
First Author: Liu S
Year: 2021
Journal: Elife
Title: Single-PanIN-seq unveils that ARID1A deficiency promotes pancreatic tumorigenesis by attenuating KRAS-induced senescence.
Volume: 10
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Publication
36001976 | J:327878
First Author: Simmler P
Year: 2022
Journal: Cell Rep
Title: SF3B1 facilitates HIF1-signaling and promotes malignancy in pancreatic cancer.
Volume: 40
Issue: 8
Pages: 111266
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Publication
34526722 | J:325768
First Author: Neuhöfer P
Year: 2021
Journal: Nature
Title: Acinar cell clonal expansion in pancreas homeostasis and carcinogenesis.
Volume: 597
Issue: 7878
Pages: 715-719
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Publication
36572673 | J:332267
First Author: Husanie H
Year: 2022
Journal: Cell Death Dis
Title: Loss of tumor suppressor WWOX accelerates pancreatic cancer development through promotion of TGFβ/BMP2 signaling.
Volume: 13
Issue: 12
Pages: 1074
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Publication
30296435 | J:309357
First Author: Görgülü K
Year: 2019
Journal: Gastroenterology
Title: Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice.
Volume: 156
Issue: 1
Pages: 203-217.e20
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Publication
35122074 | J:322704
First Author: Falcomatà C
Year: 2022
Journal: Nat Cancer
Title: Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment.
Volume: 3
Issue: 3
Pages: 318-336
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Publication
30058725 | J:267566
First Author: Saponara E
Year: 2018
Journal: J Pathol
Title: Serotonin uptake is required for Rac1 activation in Kras-induced acinar-to-ductal metaplasia in the pancreas.
Volume: 246
Issue: 3
Pages: 352-365
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Publication
31999644 | J:314868
First Author: Swain SM
Year: 2020
Journal: J Clin Invest
Title: TRPV4 channel opening mediates pressure-induced pancreatitis initiated by Piezo1 activation.
Volume: 130
Issue: 5
Pages: 2527-2541
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Publication
36388953 | J:331590
First Author: van der Heijden ME
Year: 2022
Journal: iScience
Title: Influence of data sampling methods on the representation of neural spiking activity in vivo.
Volume: 25
Issue: 11
Pages: 105429
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Publication
23041330 | J:257245
First Author: Neuhöfer P
Year: 2013
Journal: Gastroenterology
Title: Deletion of IκBα activates RelA to reduce acute pancreatitis in mice through up-regulation of Spi2A.
Volume: 144
Issue: 1
Pages: 192-201
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Publication
8861960 | J:50644
First Author: Krapp A
Year: 1996
Journal: EMBO J
Title: The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein.
Volume: 15
Issue: 16
Pages: 4317-29
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14699589 | J:87320
First Author: Jensen J
Year: 2004
Journal: Dev Dyn
Title: Gene regulatory factors in pancreatic development.
Volume: 229
Issue: 1
Pages: 176-200
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Publication
11318877 | J:62777
First Author: Obata J
Year: 2001
Journal: Genes Cells
Title: p48 subunit of mouse PTF1 binds to RBP-Jkappa/CBF-1, the intracellular mediator of Notch signalling, and is expressed in the neural tube of early stage embryos.
Volume: 6
Issue: 4
Pages: 345-60
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27180906 | J:234471
First Author: Kugel S
Year: 2016
Journal: Cell
Title: SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b.
Volume: 165
Issue: 6
Pages: 1401-1415
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Publication
26255562 | J:273952
First Author: Nagathihalli NS
Year: 2015
Journal: Gastroenterology
Title: Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer.
Volume: 149
Issue: 7
Pages: 1932-1943.e9
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37641131 | J:348898
First Author: Bastos N
Year: 2023
Journal: J Transl Med
Title: SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression.
Volume: 21
Issue: 1
Pages: 578
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21075310 | J:166831
First Author: Lee KE
Year: 2010
Journal: Cancer Cell
Title: Oncogenic KRas suppresses inflammation-associated senescence of pancreatic ductal cells.
Volume: 18
Issue: 5
Pages: 448-58
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28504719 | J:247823
First Author: Kawauchi D
Year: 2017
Journal: Oncogene
Title: Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells.
Volume: 36
Issue: 37
Pages: 5231-5242
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28087712 | J:238701
First Author: Roy N
Year: 2016
Journal: Genes Dev
Title: PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance.
Volume: 30
Issue: 24
Pages: 2669-2683
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Publication
34303658 | J:312408
First Author: Zhang Z
Year: 2021
Journal: Gastroenterology
Title: AGR2-Dependent Nuclear Import of RNA Polymerase II Constitutes a Specific Target of Pancreatic Ductal Adenocarcinoma in the Context of Wild-Type p53.
Volume: 161
Issue: 5
Pages: 1601-1614.e23
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Publication
31911451 | J:285832
First Author: Zhang Y
Year: 2020
Journal: Cancer Discov
Title: Regulatory T-cell Depletion Alters the Tumor Microenvironment and Accelerates Pancreatic Carcinogenesis.
Volume: 10
Issue: 3
Pages: 422-439
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Publication
23470560 | J:310987
First Author: Diersch S
Year: 2013
Journal: Oncotarget
Title: Efemp1 and p27(Kip1) modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models.
Volume: 4
Issue: 2
Pages: 277-88
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Publication
27454298 | J:237113
First Author: Lesina M
Year: 2016
Journal: J Clin Invest
Title: RelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis.
Volume: 126
Issue: 8
Pages: 2919-32
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Publication
22564796 | J:185802
First Author: Orvis GD
Year: 2012
Journal: Dev Biol
Title: The engrailed homeobox genes are required in multiple cell lineages to coordinate sequential formation of fissures and growth of the cerebellum.
Volume: 367
Issue: 1
Pages: 25-39
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Publication
31597100 | J:286110
First Author: Mills BN
Year: 2019
Journal: Cell Rep
Title: Stereotactic Body Radiation and Interleukin-12 Combination Therapy Eradicates Pancreatic Tumors by Repolarizing the Immune Microenvironment.
Volume: 29
Issue: 2
Pages: 406-421.e5
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Publication
24097820 | J:205411
First Author: Zhang Y
Year: 2013
Journal: Cancer Res
Title: Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistance.
Volume: 73
Issue: 20
Pages: 6359-74
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Publication
21481788 | J:170981
First Author: Lesina M
Year: 2011
Journal: Cancer Cell
Title: Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer.
Volume: 19
Issue: 4
Pages: 456-69
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Publication
29808009 | J:336458
First Author: Ruess DA
Year: 2018
Journal: Nat Med
Title: Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase.
Volume: 24
Issue: 7
Pages: 954-960
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Publication
33307028 | J:308020
First Author: Peran I
Year: 2021
Journal: Gastroenterology
Title: Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice.
Volume: 160
Issue: 4
Pages: 1359-1372.e13
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Publication
17114584 | J:116130
First Author: Bardeesy N
Year: 2006
Journal: Genes Dev
Title: Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.
Volume: 20
Issue: 22
Pages: 3130-46
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Publication
15894267 | J:98936
First Author: Hingorani SR
Year: 2005
Journal: Cancer Cell
Title: Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice.
Volume: 7
Issue: 5
Pages: 469-83
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Publication
23453624 | J:197054
First Author: Eser S
Year: 2013
Journal: Cancer Cell
Title: Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer.
Volume: 23
Issue: 3
Pages: 406-20
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Publication
32541668 | J:291708
First Author: Perkail S
Year: 2020
Journal: Nat Commun
Title: BAP1 is a haploinsufficient tumor suppressor linking chronic pancreatitis to pancreatic cancer in mice.
Volume: 11
Issue: 1
Pages: 3018
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Publication
27032419 | J:231905
First Author: Hendley AM
Year: 2016
Journal: Cancer Res
Title: p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia.
Volume: 76
Issue: 11
Pages: 3351-63
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21481787 | J:170982
First Author: Fukuda A
Year: 2011
Journal: Cancer Cell
Title: Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression.
Volume: 19
Issue: 4
Pages: 441-55
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Publication
25106646 | J:216066
 
First Author: Demir IE
Year: 2014
Journal: J Natl Cancer Inst
Title: Investigation of Schwann cells at neoplastic cell sites before the onset of cancer invasion.
Volume: 106
Issue: 8
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31915130 | J:285785
First Author: Das S
Year: 2020
Journal: Cancer Res
Title: Tumor Cell-Derived IL1β Promotes Desmoplasia and Immune Suppression in Pancreatic Cancer.
Volume: 80
Issue: 5
Pages: 1088-1101
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Publication
25939753 | J:222769
First Author: Bednar F
Year: 2015
Journal: Carcinogenesis
Title: Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism.
Volume: 36
Issue: 7
Pages: 730-8
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Publication
24229643 | J:275016
First Author: Fleming JT
Year: 2013
Journal: Dev Cell
Title: The Purkinje neuron acts as a central regulator of spatially and functionally distinct cerebellar precursors.
Volume: 27
Issue: 3
Pages: 278-92
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12624426 | J:126939
First Author: Herrera PL
Year: 2002
Journal: Endocrine
Title: Pancreatic cell lineage analyses in mice.
Volume: 19
Issue: 3
Pages: 267-78
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24089514 | J:209044
First Author: El-Gohary Y
Year: 2014
Journal: Diabetes
Title: A smad signaling network regulates islet cell proliferation.
Volume: 63
Issue: 1
Pages: 224-36
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21684285 | J:275200
First Author: Heid I
Year: 2011
Journal: Gastroenterology
Title: Early requirement of Rac1 in a mouse model of pancreatic cancer.
Volume: 141
Issue: 2
Pages: 719-30, 730.e1-7
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23426178 | J:196394
First Author: Zhang H
Year: 2013
Journal: J Clin Invest
Title: IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality.
Volume: 123
Issue: 3
Pages: 1019-31
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Publication
29604291 | J:273105
First Author: Kimura Y
Year: 2018
Journal: Gastroenterology
Title: ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice.
Volume: 155
Issue: 1
Pages: 194-209.e2
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24411943 | J:210543
First Author: Flanagan SE
Year: 2014
Journal: Cell Metab
Title: Analysis of transcription factors key for mouse pancreatic development establishes NKX2-2 and MNX1 mutations as causes of neonatal diabetes in man.
Volume: 19
Issue: 1
Pages: 146-54
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Publication
26683340 | J:316512
 
First Author: Kong B
Year: 2015
Journal: Mol Cancer
Title: Pancreas-specific activation of mTOR and loss of p53 induce tumors reminiscent of acinar cell carcinoma.
Volume: 14
Pages: 212
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35982178 | J:330821
First Author: Yuan M
Year: 2022
Journal: Nat Cancer
Title: Cancer-associated fibroblasts employ NUFIP1-dependent autophagy to secrete nucleosides and support pancreatic tumor growth.
Volume: 3
Issue: 8
Pages: 945-960
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32183949 | J:285844
First Author: Hegde S
Year: 2020
Journal: Cancer Cell
Title: Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer.
Volume: 37
Issue: 3
Pages: 289-307.e9
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29317452 | J:256651
     
First Author: Yang A
Year: 2018
Journal: Cancer Discov
Title: Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms.
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25497209 | J:266514
First Author: Diakopoulos KN
Year: 2015
Journal: Gastroenterology
Title: Impaired autophagy induces chronic atrophic pancreatitis in mice via sex- and nutrition-dependent processes.
Volume: 148
Issue: 3
Pages: 626-638.e17
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29975347 | J:289682
First Author: Saloman JL
Year: 2018
Journal: Pancreas
Title: Systemic Depletion of Nerve Growth Factor Inhibits Disease Progression in a Genetically Engineered Model of Pancreatic Ductal Adenocarcinoma.
Volume: 47
Issue: 7
Pages: 856-863
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29364867 | J:257934
First Author: Mueller S
Year: 2018
Journal: Nature
Title: Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes.
Volume: 554
Issue: 7690
Pages: 62-68
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22975374 | J:190126
First Author: Ardito CM
Year: 2012
Journal: Cancer Cell
Title: EGF receptor is required for KRAS-induced pancreatic tumorigenesis.
Volume: 22
Issue: 3
Pages: 304-17
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24898060 | J:214456
First Author: Alderton GK
Year: 2014
Journal: Nat Rev Cancer
Title: Microenvironment: An exercise in restraint.
Volume: 14
Issue: 7
Pages: 449
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28178232 | J:243963
First Author: Genovese G
Year: 2017
Journal: Nature
Title: Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer.
Volume: 542
Issue: 7641
Pages: 362-366
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24954535 | J:214523
First Author: Kapoor A
Year: 2014
Journal: Cell
Title: Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer.
Volume: 158
Issue: 1
Pages: 185-197
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36653361 | J:332636
First Author: Ferguson LP
Year: 2023
Journal: Nat Commun
Title: Smarcd3 is an epigenetic modulator of the metabolic landscape in pancreatic ductal adenocarcinoma.
Volume: 14
Issue: 1
Pages: 292
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26390243 | J:228905
First Author: Mazur PK
Year: 2015
Journal: Nat Med
Title: Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
Volume: 21
Issue: 10
Pages: 1163-71
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19136624 | J:143478
First Author: Nolan-Stevaux O
Year: 2009
Journal: Genes Dev
Title: GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation.
Volume: 23
Issue: 1
Pages: 24-36
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34175279 | J:313592
First Author: Kabacaoğlu D
Year: 2021
Journal: Gastroenterology
Title: A Pancreas-Specific Ptf1a-Driven Cre Mouse Line Causes Paternally Transmitted Germline Recombination.
Volume: 161
Issue: 5
Pages: 1695-1697.e4
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29593283 | J:260745
First Author: Meyer MA
Year: 2018
Journal: Nat Commun
Title: Breast and pancreatic cancer interrupt IRF8-dependent dendritic cell development to overcome immune surveillance.
Volume: 9
Issue: 1
Pages: 1250
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Publication
38816352 | J:349100
First Author: Park JH
Year: 2024
Journal: Nat Commun
Title: Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression.
Volume: 15
Issue: 1
Pages: 4099
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24561622 | J:212984
First Author: von Figura G
Year: 2014
Journal: Nat Cell Biol
Title: The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma.
Volume: 16
Issue: 3
Pages: 255-67
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25119024 | J:217085
First Author: Viale A
Year: 2014
Journal: Nature
Title: Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.
Volume: 514
Issue: 7524
Pages: 628-32
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39048609 | J:352531
First Author: Suzuki Y
Year: 2024
Journal: Sci Rep
Title: Activation of STING in pancreatic cancer-associated fibroblasts exerts an antitumor effect by enhancing tumor immunity.
Volume: 14
Issue: 1
Pages: 17071
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24847881 | J:213209
First Author: Mazur PK
Year: 2014
Journal: Nature
Title: SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.
Volume: 510
Issue: 7504
Pages: 283-7
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30700911 | J:270381
First Author: Messal HA
Year: 2019
Journal: Nature
Title: Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis.
Volume: 566
Issue: 7742
Pages: 126-130
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29844119 | J:265549
First Author: Cheung PF
Year: 2018
Journal: Cancer Res
Title: Notch-Induced Myeloid Reprogramming in Spontaneous Pancreatic Ductal Adenocarcinoma by Dual Genetic Targeting.
Volume: 78
Issue: 17
Pages: 4997-5010
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Publication
28057438 | J:274473
 
First Author: Lubeseder-Martellato C
Year: 2017
Journal: EBioMedicine
Title: Oncogenic KRas-induced Increase in Fluid-phase Endocytosis is Dependent on N-WASP and is Required for the Formation of Pancreatic Preneoplastic Lesions.
Volume: 15
Pages: 90-99
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Publication
36862034 | J:335420
First Author: Yoon SJ
Year: 2023
Journal: Cancer Res
Title: Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors.
Volume: 83
Issue: 9
Pages: 1426-1442
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Publication
28630313 | J:244932
First Author: Li M
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Targeting reactive nitrogen species suppresses hereditary pancreatic cancer.
Volume: 114
Issue: 27
Pages: 7106-7111
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27281208 | J:235743
First Author: Fox RG
Year: 2016
Journal: Nature
Title: Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.
Volume: 534
Issue: 7607
Pages: 407-411
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Publication
37625403 | J:349674
First Author: Mahadevan KK
Year: 2023
Journal: Dev Cell
Title: Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8(+) T cells.
Volume: 58
Issue: 17
Pages: 1562-1577.e8
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30955884 | J:283863
First Author: Lytle NK
Year: 2019
Journal: Cell
Title: A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma.
Volume: 177
Issue: 3
Pages: 572-586.e22
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Publication
20624967 | J:162569
First Author: Mazur PK
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma.
Volume: 107
Issue: 30
Pages: 13438-43
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Publication
24803537 | J:260283
First Author: Zhang W
Year: 2014
Journal: Sci Signal
Title: Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma.
Volume: 7
Issue: 324
Pages: ra42
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Publication
25915585 | J:222971
First Author: Usui Y
Year: 2015
Journal: J Clin Invest
Title: Neurovascular crosstalk between interneurons and capillaries is required for vision.
Volume: 125
Issue: 6
Pages: 2335-46
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Publication
27297878 | J:236027
 
First Author: Khoriaty R
Year: 2016
Journal: Sci Rep
Title: Pancreatic SEC23B deficiency is sufficient to explain the perinatal lethality of germline SEC23B deficiency in mice.
Volume: 6
Pages: 27802
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Publication
27805050 | J:252550
 
First Author: Badura A
Year: 2016
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