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Search results 801 to 900 out of 930 for Sim1

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Type Details Score
Genotype
Symbol: Gli2/Gli2 Gli3/Gli3
Background: involves: 101/H * C3H/HeH * C57BL * CBA/H * Swiss Webster
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Laryea G
Year: 2013
Journal: Mol Endocrinol
Title: Disrupting hypothalamic glucocorticoid receptors causes HPA axis hyperactivity and excess adiposity.
Volume: 27
Issue: 10
Pages: 1655-65
Publication
First Author: Chiappini F
Year: 2011
Journal: J Biol Chem
Title: Lack of cAMP-response element-binding protein 1 in the hypothalamus causes obesity.
Volume: 286
Issue: 10
Pages: 8094-105
Publication
First Author: Samuelsson AS
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Central role for melanocortin-4 receptors in offspring hypertension arising from maternal obesity.
Volume: 113
Issue: 43
Pages: 12298-12303
Publication
First Author: Strembitska A
Year: 2022
Journal: Nat Commun
Title: Lipid biosynthesis enzyme Agpat5 in AgRP-neurons is required for insulin-induced hypoglycemia sensing and glucagon secretion.
Volume: 13
Issue: 1
Pages: 5761
Publication
First Author: Gilbert ML
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: Expression of a dominant negative PKA mutation in the kidney elicits a diabetes insipidus phenotype.
Volume: 308
Issue: 6
Pages: F627-38
Publication
First Author: Biancardi VC
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: Cross talk between AT1 receptors and Toll-like receptor 4 in microglia contributes to angiotensin II-derived ROS production in the hypothalamic paraventricular nucleus.
Volume: 310
Issue: 3
Pages: H404-15
Publication
First Author: de Kloet AD
Year: 2013
Journal: J Neurosci
Title: Angiotensin type 1a receptors in the paraventricular nucleus of the hypothalamus protect against diet-induced obesity.
Volume: 33
Issue: 11
Pages: 4825-33
Genotype
Symbol: Mc4r/Mc4r Tg(Sim1-cre)1Lowl/?
Background: involves: 129S4/SvJae * C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mc4r/Mc4r Tg(Sim1-cre)2Lowl/?
Background: involves: 129S4/SvJae * C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mc4r/Mc4r Tg(Sim1-cre)#Lowl/?
Background: involves: 129S4/SvJae * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Sim1-cre)1Lowl/?
Background: involves: 129S4/SvJaeSor * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Sim1-cre)KJ27Gsat/?
Background: involves: 129S4/SvJaeSor * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dnmt3a/Dnmt3a Tg(Sim1-cre)#Lowl/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Sim1-cre)2Lowl/?
Background: involves: 129S4/SvJaeSor * FVB
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Semple E
Year: 2019
Journal: Mol Neurobiol
Title: Oxytocin Neurons Enable Melanocortin Regulation of Male Sexual Function in Mice.
Volume: 56
Issue: 9
Pages: 6310-6323
Publication  
First Author: Li L
Year: 2021
Journal: J Exp Med
Title: The atypical antipsychotic risperidone targets hypothalamic melanocortin 4 receptors to cause weight gain.
Volume: 218
Issue: 7
Publication
First Author: Arble DM
Year: 2015
Journal: Endocrinology
Title: The melanocortin-4 receptor integrates circadian light cues and metabolism.
Volume: 156
Issue: 5
Pages: 1685-91
Publication
First Author: Hinton AO Jr
Year: 2016
Journal: Hypertension
Title: Estrogen Receptor-α in the Medial Amygdala Prevents Stress-Induced Elevations in Blood Pressure in Females.
Volume: 67
Issue: 6
Pages: 1321-30
Publication  
First Author: Kawakami-Mori F
Year: 2018
Journal: JCI Insight
Title: Aberrant DNA methylation of hypothalamic angiotensin receptor in prenatal programmed hypertension.
Volume: 3
Issue: 21
Publication
First Author: Chiappini F
Year: 2013
Journal: Mol Cell Endocrinol
Title: Family members CREB and CREM control thyrotropin-releasing hormone (TRH) expression in the hypothalamus.
Volume: 365
Issue: 1
Pages: 84-94
Publication
First Author: de Souza Cordeiro LM
Year: 2021
Journal: Diabetologia
Title: Hypothalamic MC4R regulates glucose homeostasis through adrenaline-mediated control of glucose reabsorption via renal GLUT2 in mice.
Volume: 64
Issue: 1
Pages: 181-194
Publication  
First Author: Fan S
Year: 2016
Journal: Sci Rep
Title: An Indirect Action Contributes to C-Fos Induction in Paraventricular Hypothalamic Nucleus by Neuropeptide Y.
Volume: 6
Pages: 19980
Publication
First Author: Siljee JE
Year: 2018
Journal: Nat Genet
Title: Subcellular localization of MC4R with ADCY3 at neuronal primary cilia underlies a common pathway for genetic predisposition to obesity.
Volume: 50
Issue: 2
Pages: 180-185
Publication
First Author: Burmeister MA
Year: 2017
Journal: Diabetes
Title: The Hypothalamic Glucagon-Like Peptide 1 Receptor Is Sufficient but Not Necessary for the Regulation of Energy Balance and Glucose Homeostasis in Mice.
Volume: 66
Issue: 2
Pages: 372-384
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Sim1-cre)1Lowl/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Sim1-cre)#Lowl/?
Background: involves: 129S4/SvJaeSor * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Sim1-cre)1Lowl/?
Background: involves: 129 * C57BL/6 * CD-1 * FVB
Zygosity: cn
Has Mutant Allele: true
Allele
Name: GLI-Kruppel family member GLI2; targeted mutation 2.1, Alexandra L Joyner
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: hedgehog acyltransferase; targeted mutation 1, Pao-Tien Chuang
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: hedgehog acyltransferase; targeted mutation 2, Pao-Tien Chuang
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: zinc finger, C4H2 domain containing; endonuclease-mediated mutation 1.1, Yu-qiang Ding
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Genotype
Symbol: Gli2/Gli2 Gli3/Gli3
Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * Swiss Webster
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Gli2/Gli2
Background: either: (involves: 129) or (involves: 129 * Black Swiss)
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Gli2/Gli2
Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * Black Swiss)
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Gli2/Gli2 Shh/Shh
Background: either: (involves: 129) or (involves: 129 * Black Swiss)
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Gli1/Gli1<+> Gli2/Gli2 Gli3/Gli3
Background: involves: 101/H * 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C3H/HeH * C57BL * CBA/H * Swiss Webster
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Rnf220/Rnf220
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Zc4h2/Zc4h2
Background: involves: C57BL/6 * FVB
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Mukerjee S
Year: 2019
Journal: Hypertension
Title: ACE2 and ADAM17 Interaction Regulates the Activity of Presympathetic Neurons.
Volume: 74
Issue: 5
Pages: 1181-1191
Publication
First Author: Kim MJ
Year: 2014
Journal: Hum Mol Genet
Title: Functional characterization of SIM1-associated enhancers.
Volume: 23
Issue: 7
Pages: 1700-8
Publication
First Author: Kasher PR
Year: 2016
Journal: Am J Hum Genet
Title: Small 6q16.1 Deletions Encompassing POU3F2 Cause Susceptibility to Obesity and Variable Developmental Delay with Intellectual Disability.
Volume: 98
Issue: 2
Pages: 363-72
Publication  
First Author: Hossain MS
Year: 2016
Journal: Sci Rep
Title: Identification of mutations through dominant screening for obesity using C57BL/6 substrains.
Volume: 6
Pages: 32453
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Allele
Name: paired box 6; targeted mutation 1, Peter Gruss
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: fuzzy planar cell polarity protein; gene trap AN0439, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
Attribute String: Null/knockout, Reporter
Genotype
Symbol: Hhat/Hhat
Background: involves: 129P2/OlaHsd * FVB/N * various
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Hhat/Hhat
Background: involves: 129P2/OlaHsd * FVB/N * various
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Hosoya T
Year: 2001
Journal: Genes Cells
Title: Defective development of secretory neurones in the hypothalamus of Arnt2-knockout mice.
Volume: 6
Issue: 4
Pages: 361-74
Publication
First Author: Zhulin IB
Year: 1997
Journal: Trends Biochem Sci
Title: PAS domain S-boxes in Archaea, Bacteria and sensors for oxygen and redox.
Volume: 22
Issue: 9
Pages: 331-3
Publication
First Author: Bosch PJ
Year: 2019
Journal: Genesis
Title: A critical role for the nuclear protein Akirin2 in the formation of mammalian muscle in vivo.
Volume: 57
Issue: 5
Pages: e23286
Publication
First Author: Nahar J
Year: 2015
Journal: Endocrinology
Title: Rapid Nongenomic Glucocorticoid Actions in Male Mouse Hypothalamic Neuroendocrine Cells Are Dependent on the Nuclear Glucocorticoid Receptor.
Volume: 156
Issue: 8
Pages: 2831-42
Publication
First Author: Jiang Z
Year: 2022
Journal: Cell Rep
Title: Stress-induced glucocorticoid desensitizes adrenoreceptors to gate the neuroendocrine response to somatic stress in male mice.
Volume: 41
Issue: 3
Pages: 111509
Publication
First Author: Zaman T
Year: 2014
Journal: J Neurosci
Title: LMO4 is essential for paraventricular hypothalamic neuronal activity and calcium channel expression to prevent hyperphagia.
Volume: 34
Issue: 1
Pages: 140-8
Publication
First Author: Li YQ
Year: 2016
Journal: J Clin Invest
Title: G(q/11)α and G(s)α mediate distinct physiological responses to central melanocortins.
Volume: 126
Issue: 1
Pages: 40-9
Publication
First Author: Chen M
Year: 2012
Journal: Endocrinology
Title: Gsα deficiency in the paraventricular nucleus of the hypothalamus partially contributes to obesity associated with Gsα mutations.
Volume: 153
Issue: 9
Pages: 4256-65
Publication
First Author: Jeanneteau FD
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus.
Volume: 109
Issue: 4
Pages: 1305-10
Publication
First Author: Mangieri LR
Year: 2018
Journal: Nat Commun
Title: A neural basis for antagonistic control of feeding and compulsive behaviors.
Volume: 9
Issue: 1
Pages: 52
Publication
First Author: Chen Y
Year: 2020
Journal: Neuron
Title: Soma-Targeted Imaging of Neural Circuits by Ribosome Tethering.
Volume: 107
Issue: 3
Pages: 454-469.e6
Publication    
First Author: Huang LW
Year: 2024
Journal: Elife
Title: Synaptic interactions between stellate cells and parvalbumin interneurons in layer 2 of the medial entorhinal cortex are organized at the scale of grid cell clusters.
Volume: 12
Publication
First Author: Zhao J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Genomic integration of ERRγ-HNF1β regulates renal bioenergetics and prevents chronic kidney disease.
Volume: 115
Issue: 21
Pages: E4910-E4919
Publication      
First Author: Gasparini S
Year: 2020
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Pre-locus coeruleus neurons in rat and mouse.
Publication
First Author: Winnubst J
Year: 2019
Journal: Cell
Title: Reconstruction of 1,000 Projection Neurons Reveals New Cell Types and Organization of Long-Range Connectivity in the Mouse Brain.
Volume: 179
Issue: 1
Pages: 268-281.e13
Publication  
First Author: Mangieri LR
Year: 2019
Journal: eNeuro
Title: Defensive Behaviors Driven by a Hypothalamic-Ventral Midbrain Circuit.
Volume: 6
Issue: 4
Publication
First Author: Sürmeli G
Year: 2015
Journal: Neuron
Title: Molecularly Defined Circuitry Reveals Input-Output Segregation in Deep Layers of the Medial Entorhinal Cortex.
Volume: 88
Issue: 5
Pages: 1040-1053
Publication
First Author: Sutton AK
Year: 2014
Journal: J Neurosci
Title: Control of food intake and energy expenditure by Nos1 neurons of the paraventricular hypothalamus.
Volume: 34
Issue: 46
Pages: 15306-18
Genotype
Symbol: Saraf/Saraf Tg(Sim1-cre)1Lowl/?
Background: involves: 129 * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Akirin2/Akirin2<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Sim1-cre)1Lowl/?
Background: involves: 129X1/SvJ * C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Akirin2/Akirin2 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Sim1-cre)1Lowl/?
Background: involves: 129X1/SvJ * C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Sim1/Sim1<+> Tg(Pdyn-EGFP)BD193Gsat/?
Background: involves: 129S6/SvEvTac * C57BL/6NCrl * FVB/NTac
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Sim1/Sim1<+> Tg(Sim1-cre)1Lowl/?
Background: involves: 129 * C57BL/6 * CD-1 * FVB
Zygosity: cn
Has Mutant Allele: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Allele
Name: methyl-CpG binding domain protein 4; targeted mutation 1, Alfonso Bellacosa
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: inturned planar cell polarity protein; targeted mutation 1.2, Aimin Liu
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: intraflagellar transport 122; targeted mutation 1, Alfonso Bellacosa
Allele Type: Targeted
Attribute String: Null/knockout
Genotype
Symbol: Fuz/Fuz
Background: involves: 129P2/OlaHsd * C3H
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Asai M
Year: 2013
Journal: Science
Title: Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity.
Volume: 341
Issue: 6143
Pages: 275-8
Publication
First Author: Jiang SZ
Year: 2023
Journal: Biol Psychiatry Glob Open Sci
Title: PACAP Controls Endocrine and Behavioral Stress Responses via Separate Brain Circuits.
Volume: 3
Issue: 4
Pages: 673-685
Publication
First Author: Wu Z
Year: 2015
Journal: J Neurosci
Title: GABAergic projections from lateral hypothalamus to paraventricular hypothalamic nucleus promote feeding.
Volume: 35
Issue: 8
Pages: 3312-8
Publication
First Author: Ramot A
Year: 2017
Journal: Nat Neurosci
Title: Hypothalamic CRFR1 is essential for HPA axis regulation following chronic stress.
Volume: 20
Issue: 3
Pages: 385-388
Publication
First Author: Chong AC
Year: 2015
Journal: Mol Metab
Title: Central insulin signaling modulates hypothalamus-pituitary-adrenal axis responsiveness.
Volume: 4
Issue: 2
Pages: 83-92
Publication
First Author: Molumby MJ
Year: 2016
Journal: Cell Rep
Title: Homophilic Protocadherin Cell-Cell Interactions Promote Dendrite Complexity.
Volume: 15
Issue: 5
Pages: 1037-1050
Publication
First Author: Kim ER
Year: 2015
Journal: J Neurosci
Title: Hypothalamic Non-AgRP, Non-POMC GABAergic Neurons Are Required for Postweaning Feeding and NPY Hyperphagia.
Volume: 35
Issue: 29
Pages: 10440-50
Publication
First Author: Lee JY
Year: 2021
Journal: Nature
Title: Dopamine facilitates associative memory encoding in the entorhinal cortex.
Volume: 598
Issue: 7880
Pages: 321-326
Publication  
First Author: Griffin H
Year: 2022
Journal: Int J Mol Sci
Title: Liraglutide Counteracts Endoplasmic Reticulum Stress in Palmitate-Treated Hypothalamic Neurons without Restoring Mitochondrial Homeostasis.
Volume: 24
Issue: 1
Publication
First Author: Kim ER
Year: 2020
Journal: Nat Commun
Title: Paraventricular hypothalamus mediates diurnal rhythm of metabolism.
Volume: 11
Issue: 1
Pages: 3794
Publication
First Author: Callahan JW
Year: 2022
Journal: J Neurosci
Title: Dysregulation of the Basal Ganglia Indirect Pathway in Early Symptomatic Q175 Huntington's Disease Mice.
Volume: 42
Issue: 10
Pages: 2080-2102
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Genotype
Symbol: Intu/Intu
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C3H
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Mbd4/Ift122/Mbd4/Ift122
Background: B6.129-Mbd4/Ift122
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Mbd4/Ift122/Mbd4/Ift122
Background: B6.129-Mbd4/Ift122
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Sohn JW
Year: 2013
Journal: Cell
Title: Melanocortin 4 receptors reciprocally regulate sympathetic and parasympathetic preganglionic neurons.
Volume: 152
Issue: 3
Pages: 612-9
Publication
First Author: Gataulin D
Year: 2023
Journal: PNAS Nexus
Title: Store-operated Ca(2+) entry regulatory factor alters murine metabolic state in an age-dependent manner via hypothalamic pathways.
Volume: 2
Issue: 3
Pages: pgad068
Publication
First Author: Atasoy D
Year: 2012
Journal: Nature
Title: Deconstruction of a neural circuit for hunger.
Volume: 488
Issue: 7410
Pages: 172-7
Publication
First Author: An JJ
Year: 2020
Journal: Nat Commun
Title: TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits.
Volume: 11
Issue: 1
Pages: 1729
Publication
First Author: Sayar-Atasoy N
Year: 2023
Journal: Nat Commun
Title: Adrenergic modulation of melanocortin pathway by hunger signals.
Volume: 14
Issue: 1
Pages: 6602
Publication
First Author: Gong R
Year: 2020
Journal: Cell
Title: Hindbrain Double-Negative Feedback Mediates Palatability-Guided Food and Water Consumption.
Volume: 182
Issue: 6
Pages: 1589-1605.e22
Publication
First Author: Piñol RA
Year: 2012
Journal: J Neurosci Methods
Title: Optogenetic approaches to characterize the long-range synaptic pathways from the hypothalamus to brain stem autonomic nuclei.
Volume: 210
Issue: 2
Pages: 238-46
Publication  
First Author: Oboti L
Year: 2018
Journal: eNeuro
Title: Amygdala Corticofugal Input Shapes Mitral Cell Responses in the Accessory Olfactory Bulb.
Volume: 5
Issue: 3
Publication
First Author: Xu Y
Year: 2019
Journal: Nat Commun
Title: Identification of a neurocircuit underlying regulation of feeding by stress-related emotional responses.
Volume: 10
Issue: 1
Pages: 3446