|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 801 to 900 out of 1099 for Smo

<< First    < Previous  |  Next >    Last >>
0.039s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
19286674 | J:147574
First Author: Norman RX
Year: 2009
Journal: Hum Mol Genet
Title: Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling.
Volume: 18
Issue: 10
Pages: 1740-54
•
•
•
•
•
Publication
25936505 | J:221657
First Author: Kong JH
Year: 2015
Journal: Dev Cell
Title: Notch activity modulates the responsiveness of neural progenitors to sonic hedgehog signaling.
Volume: 33
Issue: 4
Pages: 373-87
•
•
•
•
•
Publication
23482494 | J:194893
First Author: Yu K
Year: 2013
Journal: Development
Title: Floor plate-derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord.
Volume: 140
Issue: 7
Pages: 1594-604
•
•
•
•
•
Publication
27320915 | J:238372
First Author: Rankin SA
Year: 2016
Journal: Cell Rep
Title: A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification.
Volume: 16
Issue: 1
Pages: 66-78
•
•
•
•
•
Publication
31167144 | J:284605
First Author: Coquenlorge S
Year: 2019
Journal: Cell Rep
Title: GLI2 Modulated by SUFU and SPOP Induces Intestinal Stem Cell Niche Signals in Development and Tumorigenesis.
Volume: 27
Issue: 10
Pages: 3006-3018.e4
•
•
•
•
•
Publication
24302887 | J:205269
First Author: Cui C
Year: 2013
Journal: PLoS Biol
Title: Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton.
Volume: 11
Issue: 11
Pages: e1001720
•
•
•
•
•
Publication
18590716 | J:138713
First Author: Cho A
Year: 2008
Journal: Dev Biol
Title: FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism.
Volume: 321
Issue: 1
Pages: 27-39
•
•
•
•
•
Publication
31604927 | J:280702
First Author: Yung T
Year: 2019
Journal: Nat Commun
Title: Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals.
Volume: 10
Issue: 1
Pages: 4647
•
•
•
•
•
Publication
36218069 | J:331486
 
First Author: Hirose T
Year: 2022
Journal: Development
Title: PAR3 restricts the expansion of neural precursor cells by regulating hedgehog signaling.
Volume: 149
Issue: 21
•
•
•
•
•
Publication
15755804 | J:98216
First Author: García-García MJ
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Analysis of mouse embryonic patterning and morphogenesis by forward genetics.
Volume: 102
Issue: 17
Pages: 5913-9
•
•
•
•
•
Publication
27414999 | J:234178
First Author: Perdigoto CN
Year: 2016
Journal: PLoS Genet
Title: Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development.
Volume: 12
Issue: 7
Pages: e1006151
•
•
•
•
•
Publication
31845891 | J:291752
   
First Author: Portal C
Year: 2019
Journal: Elife
Title: Primary cilia deficiency in neural crest cells models anterior segment dysgenesis in mouse.
Volume: 8
•
•
•
•
•
Publication
14973295 | J:88577
First Author: Mu X
Year: 2004
Journal: Development
Title: Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina.
Volume: 131
Issue: 6
Pages: 1197-210
•
•
•
•
•
Publication
36920550 | J:336100
First Author: Brütsch SM
Year: 2023
Journal: Cell Mol Life Sci
Title: Mesenchyme-derived vertebrate lonesome kinase controls lung organogenesis by altering the matrisome.
Volume: 80
Issue: 4
Pages: 89
•
•
•
•
•
Publication
22076636 | J:192712
First Author: Meadows SM
Year: 2012
Journal: Circ Res
Title: Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels.
Volume: 110
Issue: 1
Pages: 34-46
•
•
•
•
•
Publication
22889265 | J:205383
First Author: Salti A
Year: 2013
Journal: Stem Cells Dev
Title: Expression of early developmental markers predicts the efficiency of embryonic stem cell differentiation into midbrain dopaminergic neurons.
Volume: 22
Issue: 3
Pages: 397-411
•
•
•
•
•
Publication
26697723 | J:233841
First Author: Inoue M
Year: 2016
Journal: Endocrinology
Title: Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice.
Volume: 157
Issue: 3
Pages: 1222-33
•
•
•
•
•
Publication
30478225 | J:272619
 
First Author: Aydoğdu N
Year: 2018
Journal: Development
Title: TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme.
Volume: 145
Issue: 23
•
•
•
•
•
Publication
17199044 | J:117334
First Author: Gritli-Linde A
Year: 2007
Journal: Dev Cell
Title: Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling.
Volume: 12
Issue: 1
Pages: 99-112
•
•
•
•
•
Publication
35905011 | J:327332
 
First Author: Kurz J
Year: 2022
Journal: Development
Title: GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter.
Volume: 149
Issue: 15
•
•
•
•
•
Publication
15306695 | J:91835
First Author: Kaput J
Year: 2004
Journal: Physiol Genomics
Title: Identification of genes contributing to the obese yellow Avy phenotype: caloric restriction, genotype, diet x genotype interactions.
Volume: 18
Issue: 3
Pages: 316-24
•
•
•
•
•
Publication
30352686 | J:270543
First Author: Tanahashi H
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Deletion of Lrp4 increases the incidence of microphthalmia.
Volume: 506
Issue: 3
Pages: 478-484
•
•
•
•
•
Publication
26238476 | J:226028
First Author: Lewandowski JP
Year: 2015
Journal: Dev Biol
Title: Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Volume: 406
Issue: 1
Pages: 92-103
•
•
•
•
•
Publication
19521566 | J:177549
First Author: Willnow T
Year: 2005
Journal: Organogenesis
Title: The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.
Volume: 2
Issue: 2
Pages: 42-7
•
•
•
•
•
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
•
•
•
•
•
Publication
29031500 | J:257654
First Author: Memic F
Year: 2018
Journal: Gastroenterology
Title: Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.
Volume: 154
Issue: 3
Pages: 624-636
•
•
•
•
•
Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
•
•
•
•
•
Publication
21731673 | J:174767
First Author: Tang F
Year: 2011
Journal: PLoS One
Title: Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
Volume: 6
Issue: 6
Pages: e21208
•
•
•
•
•
Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
•
•
•
•
•
Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
•
•
•
•
•
Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
•
•
•
•
•
Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
•
•
•
•
•
Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
•
•
•
•
•
Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
•
•
•
•
•
Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
•
•
•
•
•
Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
•
•
•
•
•
Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
•
•
•
•
•
Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
•
•
•
•
•
Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
•
•
•
•
•
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
HT Sample
GSM279679 1
       
Organism Name: mouse, laboratory
Notes: Smo gain-of-function mutant limb bud
Curation Status: Not curated (Transgenic sample)
•
•
•
•
•
HT Sample
GSM279680 1
       
Organism Name: mouse, laboratory
Notes: Smo gain-of-function mutant limb bud
Curation Status: Not curated (Transgenic sample)
•
•
•
•
•
HT Sample
GSM279681 1
       
Organism Name: mouse, laboratory
Notes: Smo gain-of-function mutant limb bud
Curation Status: Not curated (Transgenic sample)
•
•
•
•
•
Publication
26130651 | J:225591
First Author: Zhao X
Year: 2015
Journal: Cancer Res
Title: RAS/MAPK Activation Drives Resistance to Smo Inhibition, Metastasis, and Tumor Evolution in Shh Pathway-Dependent Tumors.
Volume: 75
Issue: 17
Pages: 3623-35
•
•
•
•
•
Publication
29463581 | J:262302
First Author: Rahman MM
Year: 2018
Journal: Cancer Res
Title: A Novel Mechanism for Activation of GLI1 by Nuclear SMO That Escapes Anti-SMO Inhibitors.
Volume: 78
Issue: 10
Pages: 2577-2588
•
•
•
•
•
GO Term
GO:0005119 | smoothened binding
•
•
•
•
•
Pathway
R-MMU-5635838 | Activation of SMO
•
•
•
•
•
Publication
36688010 | J:350106
First Author: George J
Year: 2022
Journal: Cancer Res Commun
Title: Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors.
Volume: 2
Issue: 6
Pages: 402-416
•
•
•
•
•
Publication
23026747 | J:188176
First Author: Caparrós-Martín JA
Year: 2013
Journal: Hum Mol Genet
Title: The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia.
Volume: 22
Issue: 1
Pages: 124-39
•
•
•
•
•
Publication
25908617 | J:223812
First Author: Caparrós-Martín JA
Year: 2015
Journal: Hum Mol Genet
Title: Specific variants in WDR35 cause a distinctive form of Ellis-van Creveld syndrome by disrupting the recruitment of the EvC complex and SMO into the cilium.
Volume: 24
Issue: 14
Pages: 4126-37
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6385332
Assay Type: RNA in situ
Annotation Date: 2020-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2856120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6385389
Age: embryonic day 12.5
Image: 1C Tbx18;Smo
Note: Loss of Smo had no effect on Tbx2 expression in the ureteric mesenchyme at E12.5.
Specimen Label: 1C Tbx18;Smo
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6385333
Assay Type: RNA in situ
Annotation Date: 2020-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2856120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6385390
Age: embryonic day 12.5
Image: 1C Tbx18;Smo
Note: Loss of Smo had no effect on Tbx3 expression in the ureteric mesenchyme at E12.5.
Specimen Label: 1C Tbx18;Smo
Detected: true
Specimen Num: 8
•
•
•
•
•
Protein Coding Gene
MGI:2445356 | Smox
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Transgene
MGI:3693107 | Tg(KRT5-SMO)#Fjs
Type: transgene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:95655 | Gas1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:105373 | Ptch1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:2151153 | Boc
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1202386 | Gas8
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1926387 | Cdon
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
Q60779
Organism: Mus musculus/domesticus
Length: 478  
Fragment?: false
•
•
•
•
•
Protein
Q01721
Organism: Mus musculus/domesticus
Length: 343  
Fragment?: false
•
•
•
•
•
Protein
Q32MD9
Organism: Mus musculus/domesticus
Length: 1250  
Fragment?: false
•
•
•
•
•
Protein
Q6AZB0
Organism: Mus musculus/domesticus
Length: 1110  
Fragment?: false
•
•
•
•
•
Protein
Q61115
Organism: Mus musculus/domesticus
Length: 1434  
Fragment?: false
•
•
•
•
•
Publication
29290584 | J:253667
First Author: Pusapati GV
Year: 2018
Journal: Dev Cell
Title: CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog.
Volume: 44
Issue: 1
Pages: 113-129.e8
•
•
•
•
•
Protein
Q99K82
Organism: Mus musculus/domesticus
Length: 555  
Fragment?: false
•
•
•
•
•
Protein
Q99K82-2
Organism: Mus musculus/domesticus
Length: 585  
Fragment?: false
•
•
•
•
•
Protein
Q99K82-9
Organism: Mus musculus/domesticus
Length: 543  
Fragment?: false
•
•
•
•
•
Protein
Q99K82-8
Organism: Mus musculus/domesticus
Length: 419  
Fragment?: false
•
•
•
•
•
Protein
Q99K82-10
Organism: Mus musculus/domesticus
Length: 190  
Fragment?: false
•
•
•
•
•
Protein
Q99K82-3
Organism: Mus musculus/domesticus
Length: 238  
Fragment?: false
•
•
•
•
•
Protein
Q99K82-7
Organism: Mus musculus/domesticus
Length: 512  
Fragment?: false
•
•
•
•
•
Protein
Q99K82-4
Organism: Mus musculus/domesticus
Length: 209  
Fragment?: false
•
•
•
•
•
Protein
Q99K82-6
Organism: Mus musculus/domesticus
Length: 536  
Fragment?: false
•
•
•
•
•
Protein
Q99K82-5
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
•
•
•
•
•
Allele
Smo<em1Smoc> | MGI:7292485
Name: smoothened, frizzled class receptor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Protein Coding Gene
MGI:96533 | Ihh
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom