|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 801 to 900 out of 998 for Snca

<< First    < Previous  |  Next >    Last >>
0.017s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Publication
32798729 | J:300567
 
First Author: Siddu A
Year: 2020
Journal: Neurobiol Dis
Title: Beneficial effects of cysteamine in Thy1-α-Syn mice and induced pluripotent stem cells with a SNCA gene triplication.
Volume: 145
Pages: 105042
•
•
•
•
•
Allele
Tg(SNCA)129Mjff | MGI:5424882
Name: transgene insertion 129, The Michael J Fox Foundation
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Publication
28413000 | J:242557
 
First Author: Chumarina M
Year: 2017
Journal: Stem Cell Res
Title: Derivation of mouse embryonic stem cell lines from tyrosine hydroxylase reporter mice crossed with a human SNCA transgenic mouse model of Parkinson's disease.
Volume: 19
Pages: 17-20
•
•
•
•
•
Allele
Tg(THY1-Snca)M1mSud | MGI:3767580
Name: transgene insertion M1m, Thomas C Sudhof
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Allele
Tg(THY1-SNCA)1Sud | MGI:3767987
Name: transgene insertion 1, Thomas C Sudhof
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Allele
Tg(THY1-SNCA*A53T)M53Sud | MGI:3768388
Name: transgene insertion M53, Thomas C Sudhof
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Allele
Snca<em1Smoc> | MGI:7292496
Name: synuclein, alpha; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Strain
MGI:6355211 | C57BL/6JSmoc-Snca<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•
Allele
Tg(THY1-SNCA*A30P)TS2Sud | MGI:3767582
Name: transgene insertion TS2, Thomas C Sudhof
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Allele
Snca<tm1Smoc> | MGI:7786934
Name: synuclein, alpha; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Strain
MGI:3767635 | STOCK Tg(THY1-Snca)M1mSud/J
Attribute String: transgenic, mutant stock
•
•
•
•
•
Strain
MGI:5498777 | B6.Cg-Tg(THY1-SNCA*A30P)TS2Sud/J
Attribute String: transgenic, congenic
•
•
•
•
•
Strain
MGI:3767637 | B6;SJL-Tg(THY1-SNCA*A30P)TS2Sud/J
Attribute String: mutant strain, transgenic
•
•
•
•
•
Strain
MGI:3784061 | C57BL/6-Tg(THY1-SNCA)1Sud/J
Attribute String: coisogenic, transgenic
•
•
•
•
•
Publication
21307242 | J:180940
First Author: Jin H
Year: 2011
Journal: J Neurosci
Title: α-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity.
Volume: 31
Issue: 6
Pages: 2035-51
•
•
•
•
•
Strain
MGI:3767638 | B6.Cg-Tg(THY1-SNCA*A53T)M53Sud/J
Attribute String: transgenic, mutant strain
•
•
•
•
•
Publication
26342897 | J:260637
 
First Author: Choi YR
Year: 2015
Journal: Neurobiol Dis
Title: FcγRIIB mediates the inhibitory effect of aggregated α-synuclein on microglial phagocytosis.
Volume: 83
Pages: 90-9
•
•
•
•
•
Publication
29035751 | J:258064
 
First Author: Zhang S
Year: 2018
Journal: Neurobiol Aging
Title: Intercellular transfer of pathogenic α-synuclein by extracellular vesicles is induced by the lipid peroxidation product 4-hydroxynonenal.
Volume: 61
Pages: 52-65
•
•
•
•
•
Publication
29298416 | J:272465
First Author: Choi YR
Year: 2018
Journal: Cell Rep
Title: Prion-like Propagation of α-Synuclein Is Regulated by the FcγRIIB-SHP-1/2 Signaling Pathway in Neurons.
Volume: 22
Issue: 1
Pages: 136-148
•
•
•
•
•
Publication
22355263 | J:298852
First Author: Lee HJ
Year: 2011
Journal: Exp Neurobiol
Title: Transmission of Synucleinopathies in the Enteric Nervous System of A53T Alpha-Synuclein Transgenic Mice.
Volume: 20
Issue: 4
Pages: 181-8
•
•
•
•
•
Allele
Tg(THY1-Snca)M2mSud | MGI:3783986
Name: transgene insertion M2m, Thomas C Sudhof
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Allele
Tg(tetO-SNCA)1Cai | MGI:4420977
Name: transgene insertion 1, Huaibin Cai
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
•
•
•
•
•
Allele
Tg(SNCA*)BXwy | MGI:7563999
Name: transgene insertion B, X William Yang
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Allele
Tg(SNCA)1Xwy | MGI:7563996
Name: transgene insertion 1, X William Yang
Allele Type: Transgenic
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(THY1-SNCA)1Sud/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(THY1-Snca)M1mSud/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(THY1-SNCA*A30P)TS2Sud/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(THY1-SNCA*A53T)M53Sud/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(THY1-SNCA*A53T)M53Sud/?
Background: B6.Cg-Tg(THY1-SNCA*A53T)M53Sud/J
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Publication
16604465 | J:107648
First Author: Gajović S
Year: 2006
Journal: Transgenic Res
Title: Unexpected rescue of alpha-synuclein and multimerin1 deletion in C57BL/6JOlaHsd mice by beta-adducin knockout.
Volume: 15
Issue: 2
Pages: 255-9
•
•
•
•
•
Allele
Del(6Snca)1Slab | MGI:2154692
 
Name: deletion, Chr 6, Schoepfer Lab 1
Allele Type: Spontaneous
•
•
•
•
•
Allele
Tg(CAG-SNCA*)1.1Ccs | MGI:3764813
Name: transgene insertion 1.1, Christine C Stichel
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Allele
Tg(Th-SNCA*)1.2Ccs | MGI:3764815
Name: transgene insertion 1.2, Christine C Stichel
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Strain
MGI:3784022 | B6.Cg-Tg(THY1-Snca)M2mSud/J
Attribute String: congenic, transgenic
•
•
•
•
•
Publication
- | J:133654
     
First Author: Sudhof TC
Year: 2008
Journal: MGI Direct Data Submission
Title: Construction of an alpha-synuclein transgenic mouse
•
•
•
•
•
Allele
Tg(THY1-SNCA*A30P)M30Sud | MGI:3810438
Name: transgene insertion M30, Thomas C Sudhof
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Allele
Tg(THY1-SNCA*A53T)F53Sud | MGI:3811331
Name: transgene insertion F53, Thomas C Sudhof
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Strain
MGI:4818994 | B6;D2-Tg(tetO-SNCA)1Cai/J
Attribute String: mutant stock, transgenic
•
•
•
•
•
Allele
Tg(Snca-EGFP)PD20Gsat | MGI:5051819
Name: transgene insertion PD20, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
•
•
•
•
•
Allele
Tg(SNCA)OVX37Rwm | MGI:5544307
Name: transgene insertion OVX37, Richard Wade-Martins
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Allele
Tg(Snca)2Nbm | MGI:5641926
Name: transgene insertion 2, Robert L Nussbaum
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Allele
Tg(Prnp-SNCA*A30P)5093Kha | MGI:6273616
Name: transgene insertion 5093, Karen Hsiao Ashe
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Strain
MGI:7564000 | FVB(B6)-Tg(SNCA*)BXwy/J
Attribute String: mutant strain, transgenic
•
•
•
•
•
Strain
MGI:7563997 | STOCK Tg(SNCA)1Xwy/J
Attribute String: mutant stock, transgenic
•
•
•
•
•
Allele
Tg(tetO/Prnp-SNCA*A53T)4360Tmd | MGI:7428915
Name: transgene insertion 4360, Ted M Dawson
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
•
•
•
•
•
Allele
Tg(CAG-SNCA*)11Ccs | MGI:7565588
Name: transgene insertion 11, Christine C Stichel
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Allele
Snca<tm1(SNCA)Cya> | MGI:7657326
Name: synuclein, alpha; targeted mutation 1, Cyagen Biosciences
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Null/knockout
•
•
•
•
•
Strain
MGI:7788781 | C57BL/6JSmoc-Snca<tm1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(THY1-Snca)M2mSud/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Strain
MGI:7442148 | C57BL/6OlaHsd-Del(6Snca)1Slab
Attribute String: coisogenic, mutant strain, spontaneous mutation
•
•
•
•
•
Allele
Snca<tm1Wtd> | MGI:2429773
Name: synuclein, alpha; targeted mutation 1, William T Dauer
Allele Type: Targeted
Attribute String: Humanized sequence, Null/knockout
•
•
•
•
•
Strain
MGI:7571060 | C57BL/6N-Tg(CAG-SNCA*)17Ccs/Ieg
Attribute String: mutant strain
•
•
•
•
•
Strain
MGI:7571059 | C57BL/6N-Tg(Th-SNCA*)15Ccs/Ieg
Attribute String: mutant strain
•
•
•
•
•
Strain
MGI:3810424 | B6;SJL-Tg(THY1-SNCA*A30P)M30Sud/J
Attribute String: congenic, transgenic
•
•
•
•
•
Publication
- | J:139867
     
First Author: Sudhof TC
Year: 2008
Journal: MGI Direct Data Submission
Title: Generation of a mutant human alpha-synuclein transgene
•
•
•
•
•
Strain
MGI:3820518 | B6.Cg-Tg(THY1-SNCA*A53T)F53Sud/J
Attribute String: congenic, transgenic
•
•
•
•
•
Strain
MGI:3811479 | STOCK Tg(THY1-SNCA*A53T)F53Sud/J
Attribute String: transgenic, mutant stock
•
•
•
•
•
Publication
- | J:140019
     
First Author: Sudhof TC
Year: 2008
Journal: MGI Direct Data Submission
Title: Generation of a mutant A53T human alpha-synuclein transgene
•
•
•
•
•
Allele
Tg(SNCA)1Nbm | MGI:4412055
Name: transgene insertion 1, Robert L Nussbaum
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Allele
Tg(SNCA*A30P)1Nbm | MGI:4412058
Name: transgene insertion 1, Robert L Nussbaum
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Allele
Tg(SNCA*A30P)2Nbm | MGI:4412059
Name: transgene insertion 2, Robert L Nussbaum
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Strain
MGI:5496556 | STOCK Tg(Snca-EGFP)PD20Gsat/Mmucd
Attribute String: mutant stock, transgenic
•
•
•
•
•
Allele
Tg(SNCA*A30P)192Rwm | MGI:5543905
Name: transgene insertion 192, Richard Wade-Martins
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Publication
32985503 | J:303353
First Author: Bengoa-Vergniory N
Year: 2020
Journal: Nat Commun
Title: CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease.
Volume: 11
Issue: 1
Pages: 4885
•
•
•
•
•
Strain
MGI:5641928 | FVB/NJ-Tg(Snca)2Nbm/J
Attribute String: coisogenic, mutant strain, transgenic
•
•
•
•
•
Publication
12598733 | J:89837
First Author: Steidl JV
Year: 2003
Journal: Neuroreport
Title: Altered short-term hippocampal synaptic plasticity in mutant alpha-synuclein transgenic mice.
Volume: 14
Issue: 2
Pages: 219-23
•
•
•
•
•
Strain
MGI:7505637 | B6;C3-Tg(tetO/Prnp-SNCA*A53T)4360Tmd/J
Attribute String: mutant stock, transgenic
•
•
•
•
•
Strain
MGI:7570282 | C57BL/6N-Tg(Prnp-SNCA*)11Ccs/Ieg
Attribute String: coisogenic, mutant strain, transgenic
•
•
•
•
•
Allele
Snca<tm1.1(SNCA)Mdk> | MGI:7576955
Name: synuclein, alpha; targeted mutation 1.1, Michael D Koob
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout
•
•
•
•
•
Allele
Snca<tm2.1(SNCA*A53T)Mdk> | MGI:7576958
Name: synuclein, alpha; targeted mutation 2.1, Michael D Koob
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout
•
•
•
•
•
Allele
Snca<tm3.1(SNCA*E46K)Mdk> | MGI:7576960
Name: synuclein, alpha; targeted mutation 3.1, Michael D Koob
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout
•
•
•
•
•
Strain
MGI:7657610 | C57BL/6N-Snca<tm1(SNCA)Cya>/Cya
Attribute String: coisogenic, targeted mutation, mutant strain
•
•
•
•
•
Genotype
Genotype
Symbol: Del(6Snca)1Slab/Del(6Snca)1Slab
Background: C57BL/6JOlaHsd
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(CAG-SNCA*)1.1Ccs/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Th-SNCA*)1.2Ccs/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Dnajc5/Dnajc5 Tg(THY1-SNCA*A30P)TS2Sud/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Dnajc5/Dnajc5 Tg(THY1-SNCA)1Sud/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Dnajc5/Dnajc5 Tg(THY1-Snca)M1mSud/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Dnajc5/Dnajc5 Tg(THY1-SNCA*A53T)M53Sud/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(THY1-SNCA*A30P)M30Sud/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(THY1-SNCA*A30P)M30Sud/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(THY1-SNCA*A53T)F53Sud/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ppif/Ppif Tg(THY1-SNCA*A53T)M53Sud/?
Background: involves: 129 * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(tetO/Prnp-SNCA*A53T)4360Tmd/?
Background: involves: C3H * C57BL/6
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
HT Experiment
E-GEOD-19534 | Alpha-synuclein deficiency affects brain Foxp1 expression and ultrasonic vocalization
Series Id: GSE19534
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
•
•
•
•
•
Publication
22187053 | J:181971
First Author: Sharma M
Year: 2012
Journal: EMBO J
Title: CSPα knockout causes neurodegeneration by impairing SNAP-25 function.
Volume: 31
Issue: 4
Pages: 829-41
•
•
•
•
•
Strain
MGI:7442150 | C57BL/6-Tg(Th-SNCA*)MI2Mgsp Del(6Snca)1Slab/J
Attribute String: coisogenic, mutant strain, transgenic, spontaneous mutation
•
•
•
•
•
Publication
31165254 | J:333800
First Author: Wegrzynowicz M
Year: 2019
Journal: Acta Neuropathol
Title: Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson's disease model.
Volume: 138
Issue: 4
Pages: 575-595
•
•
•
•
•
Publication
23632635 | J:199193
First Author: Tello JA
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Reproductive physiology of a humanized GnRH receptor mouse model: application in evaluation of human-specific analogs.
Volume: 305
Issue: 1
Pages: E67-77
•
•
•
•
•
Allele
Tg(Prnp-SNCA*A53T)AAub | MGI:3723258
Name: transgene insertion A, Georg Auburger
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Publication
23223297 | J:193193
First Author: Gan L
Year: 2012
Journal: J Neurosci
Title: Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model.
Volume: 32
Issue: 49
Pages: 17775-87
•
•
•
•
•
Allele
Tg(SNCA*A53T)1Nbm | MGI:4412061
Name: transgene insertion 1, Robert L Nussbaum
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Allele
Tg(SNCA*A53T)2Nbm | MGI:4412066
Name: transgene insertion 2, Robert L Nussbaum
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom