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Search results 801 to 900 out of 998 for Snca

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Type Details Score
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication  
First Author: Siddu A
Year: 2020
Journal: Neurobiol Dis
Title: Beneficial effects of cysteamine in Thy1-α-Syn mice and induced pluripotent stem cells with a SNCA gene triplication.
Volume: 145
Pages: 105042
Allele
Name: transgene insertion 129, The Michael J Fox Foundation
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication  
First Author: Chumarina M
Year: 2017
Journal: Stem Cell Res
Title: Derivation of mouse embryonic stem cell lines from tyrosine hydroxylase reporter mice crossed with a human SNCA transgenic mouse model of Parkinson's disease.
Volume: 19
Pages: 17-20
Allele
Name: transgene insertion M1m, Thomas C Sudhof
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Thomas C Sudhof
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion M53, Thomas C Sudhof
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: synuclein, alpha; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Allele
Name: transgene insertion TS2, Thomas C Sudhof
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: synuclein, alpha; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Strain
Attribute String: transgenic, mutant stock
Strain
Attribute String: transgenic, congenic
Strain
Attribute String: mutant strain, transgenic
Strain
Attribute String: coisogenic, transgenic
Publication
First Author: Jin H
Year: 2011
Journal: J Neurosci
Title: α-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity.
Volume: 31
Issue: 6
Pages: 2035-51
Strain
Attribute String: transgenic, mutant strain
Publication  
First Author: Choi YR
Year: 2015
Journal: Neurobiol Dis
Title: FcγRIIB mediates the inhibitory effect of aggregated α-synuclein on microglial phagocytosis.
Volume: 83
Pages: 90-9
Publication  
First Author: Zhang S
Year: 2018
Journal: Neurobiol Aging
Title: Intercellular transfer of pathogenic α-synuclein by extracellular vesicles is induced by the lipid peroxidation product 4-hydroxynonenal.
Volume: 61
Pages: 52-65
Publication
First Author: Choi YR
Year: 2018
Journal: Cell Rep
Title: Prion-like Propagation of α-Synuclein Is Regulated by the FcγRIIB-SHP-1/2 Signaling Pathway in Neurons.
Volume: 22
Issue: 1
Pages: 136-148
Publication
First Author: Lee HJ
Year: 2011
Journal: Exp Neurobiol
Title: Transmission of Synucleinopathies in the Enteric Nervous System of A53T Alpha-Synuclein Transgenic Mice.
Volume: 20
Issue: 4
Pages: 181-8
Allele
Name: transgene insertion M2m, Thomas C Sudhof
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Huaibin Cai
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
Allele
Name: transgene insertion B, X William Yang
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion 1, X William Yang
Allele Type: Transgenic
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
Genotype
Symbol: Tg(THY1-SNCA)1Sud/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(THY1-Snca)M1mSud/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(THY1-SNCA*A30P)TS2Sud/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(THY1-SNCA*A53T)M53Sud/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(THY1-SNCA*A53T)M53Sud/?
Background: B6.Cg-Tg(THY1-SNCA*A53T)M53Sud/J
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Gajović S
Year: 2006
Journal: Transgenic Res
Title: Unexpected rescue of alpha-synuclein and multimerin1 deletion in C57BL/6JOlaHsd mice by beta-adducin knockout.
Volume: 15
Issue: 2
Pages: 255-9
Allele  
Name: deletion, Chr 6, Schoepfer Lab 1
Allele Type: Spontaneous
Allele
Name: transgene insertion 1.1, Christine C Stichel
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion 1.2, Christine C Stichel
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Strain
Attribute String: congenic, transgenic
Publication      
First Author: Sudhof TC
Year: 2008
Journal: MGI Direct Data Submission
Title: Construction of an alpha-synuclein transgenic mouse
Allele
Name: transgene insertion M30, Thomas C Sudhof
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion F53, Thomas C Sudhof
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Strain
Attribute String: mutant stock, transgenic
Allele
Name: transgene insertion PD20, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion OVX37, Richard Wade-Martins
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion 2, Robert L Nussbaum
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 5093, Karen Hsiao Ashe
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: mutant strain, transgenic
Strain
Attribute String: mutant stock, transgenic
Allele
Name: transgene insertion 4360, Ted M Dawson
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
Allele
Name: transgene insertion 11, Christine C Stichel
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: synuclein, alpha; targeted mutation 1, Cyagen Biosciences
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Null/knockout
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Genotype
Symbol: Tg(THY1-Snca)M2mSud/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
Strain
Attribute String: coisogenic, mutant strain, spontaneous mutation
Allele
Name: synuclein, alpha; targeted mutation 1, William T Dauer
Allele Type: Targeted
Attribute String: Humanized sequence, Null/knockout
Strain
Attribute String: mutant strain
Strain
Attribute String: mutant strain
Strain
Attribute String: congenic, transgenic
Publication      
First Author: Sudhof TC
Year: 2008
Journal: MGI Direct Data Submission
Title: Generation of a mutant human alpha-synuclein transgene
Strain
Attribute String: congenic, transgenic
Strain
Attribute String: transgenic, mutant stock
Publication      
First Author: Sudhof TC
Year: 2008
Journal: MGI Direct Data Submission
Title: Generation of a mutant A53T human alpha-synuclein transgene
Allele
Name: transgene insertion 1, Robert L Nussbaum
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion 1, Robert L Nussbaum
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion 2, Robert L Nussbaum
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Strain
Attribute String: mutant stock, transgenic
Allele
Name: transgene insertion 192, Richard Wade-Martins
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Bengoa-Vergniory N
Year: 2020
Journal: Nat Commun
Title: CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease.
Volume: 11
Issue: 1
Pages: 4885
Strain
Attribute String: coisogenic, mutant strain, transgenic
Publication
First Author: Steidl JV
Year: 2003
Journal: Neuroreport
Title: Altered short-term hippocampal synaptic plasticity in mutant alpha-synuclein transgenic mice.
Volume: 14
Issue: 2
Pages: 219-23
Strain
Attribute String: mutant stock, transgenic
Strain
Attribute String: coisogenic, mutant strain, transgenic
Allele
Name: synuclein, alpha; targeted mutation 1.1, Michael D Koob
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout
Allele
Name: synuclein, alpha; targeted mutation 2.1, Michael D Koob
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout
Allele
Name: synuclein, alpha; targeted mutation 3.1, Michael D Koob
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout
Strain
Attribute String: coisogenic, targeted mutation, mutant strain
Genotype
Symbol: Del(6Snca)1Slab/Del(6Snca)1Slab
Background: C57BL/6JOlaHsd
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-SNCA*)1.1Ccs/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Th-SNCA*)1.2Ccs/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Dnajc5/Dnajc5 Tg(THY1-SNCA*A30P)TS2Sud/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Dnajc5/Dnajc5 Tg(THY1-SNCA)1Sud/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Dnajc5/Dnajc5 Tg(THY1-Snca)M1mSud/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Dnajc5/Dnajc5 Tg(THY1-SNCA*A53T)M53Sud/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(THY1-SNCA*A30P)M30Sud/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(THY1-SNCA*A30P)M30Sud/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(THY1-SNCA*A53T)F53Sud/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Ppif/Ppif Tg(THY1-SNCA*A53T)M53Sud/?
Background: involves: 129 * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(tetO/Prnp-SNCA*A53T)4360Tmd/?
Background: involves: C3H * C57BL/6
Zygosity: cn
Has Mutant Allele: true
HT Experiment
Series Id: GSE19534
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Sharma M
Year: 2012
Journal: EMBO J
Title: CSPα knockout causes neurodegeneration by impairing SNAP-25 function.
Volume: 31
Issue: 4
Pages: 829-41
Strain
Attribute String: coisogenic, mutant strain, transgenic, spontaneous mutation
Publication
First Author: Wegrzynowicz M
Year: 2019
Journal: Acta Neuropathol
Title: Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson's disease model.
Volume: 138
Issue: 4
Pages: 575-595
Publication
First Author: Tello JA
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Reproductive physiology of a humanized GnRH receptor mouse model: application in evaluation of human-specific analogs.
Volume: 305
Issue: 1
Pages: E67-77
Allele
Name: transgene insertion A, Georg Auburger
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Gan L
Year: 2012
Journal: J Neurosci
Title: Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model.
Volume: 32
Issue: 49
Pages: 17775-87
Allele
Name: transgene insertion 1, Robert L Nussbaum
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion 2, Robert L Nussbaum
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence