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Search results 801 to 900 out of 998 for Tal1

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Type Details Score
Publication
28219675 | J:241012
First Author: Lee M
Year: 2017
Journal: Dev Biol
Title: Tcf7l2 plays crucial roles in forebrain development through regulation of thalamic and habenular neuron identity and connectivity.
Volume: 424
Issue: 1
Pages: 62-76
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Publication
33053343 | J:305279
First Author: Morello F
Year: 2020
Journal: Cell Rep
Title: Molecular Fingerprint and Developmental Regulation of the Tegmental GABAergic and Glutamatergic Neurons Derived from the Anterior Hindbrain.
Volume: 33
Issue: 2
Pages: 108268
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Publication
15306695 | J:91835
First Author: Kaput J
Year: 2004
Journal: Physiol Genomics
Title: Identification of genes contributing to the obese yellow Avy phenotype: caloric restriction, genotype, diet x genotype interactions.
Volume: 18
Issue: 3
Pages: 316-24
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Publication
38374152 | J:345473
First Author: Lee JG
Year: 2024
Journal: Nat Commun
Title: PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development.
Volume: 15
Issue: 1
Pages: 1487
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Publication
37298722 | J:336866
 
First Author: Puelles L
Year: 2023
Journal: Int J Mol Sci
Title: The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer.
Volume: 24
Issue: 11
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Publication
18557763 | J:140152
First Author: Stevens JD
Year: 2008
Journal: Differentiation
Title: Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation.
Volume: 76
Issue: 9
Pages: 1006-22
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Publication
26930384 | J:231595
First Author: Gurdziel K
Year: 2016
Journal: Dev Dyn
Title: Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.
Volume: 245
Issue: 5
Pages: 614-26
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Publication
11044609 | J:65651
First Author: Neidhardt L
Year: 2000
Journal: Mech Dev
Title: Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos.
Volume: 98
Issue: 1-2
Pages: 77-94
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Publication
19521566 | J:177549
First Author: Willnow T
Year: 2005
Journal: Organogenesis
Title: The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.
Volume: 2
Issue: 2
Pages: 42-7
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
8605871 | J:102013
First Author: Larson RC
Year: 1996
Journal: EMBO J
Title: Protein dimerization between Lmo2 (Rbtn2) and Tal1 alters thymocyte development and potentiates T cell tumorigenesis in transgenic mice.
Volume: 15
Issue: 5
Pages: 1021-7
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Publication
29326336 | J:260466
First Author: Leong WZ
Year: 2017
Journal: Genes Dev
Title: ARID5B as a critical downstream target of the TAL1 complex that activates the oncogenic transcriptional program and promotes T-cell leukemogenesis.
Volume: 31
Issue: 23-24
Pages: 2343-2360
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Protein Coding Gene
MGI:107477 | Stil
Type: protein_coding_gene
Organism: mouse, laboratory
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Interaction Experiment
Hu X (2009)
Description: LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis.
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HT Experiment
E-MTAB-4026 | *Gastrulation* Single-cell RNA sequencing of mouse embryos with Tal1 (Scl) knockout - Bertie Gottgens (Gastrulation_RNA_Seq-sc-3711)
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
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Interaction Experiment
Huang S (2000)
Description: mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factor.
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Interaction Experiment
Kusy S (2011)
Description: Adult hematopoiesis is regulated by TIF1, a repressor of TAL1 and PU.1 transcriptional activity.
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Publication
10688671 | -
First Author: Huang S
Year: 2000
Journal: Mol Cell Biol
Title: mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factor.
Volume: 20
Issue: 6
Pages: 2248-59
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GO Term
GO:0070353 | GATA1-TAL1-TCF3-Lmo2 complex
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GO Term
GO:0070354 | GATA2-TAL1-TCF3-Lmo2 complex
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Allele
Tal1<tm1Sho> | MGI:1857254
Name: T cell acute lymphocytic leukemia 1; targeted mutation 1, Stuart Orkin
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:2162464 | B6.129S4-Tal1<tm1Sho>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:2161989 | B6;129S4-Tal1<tm1Sho>/J
Attribute String: targeted mutation, mutant stock
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Allele
Tg(Tal1-cre/ERT)42-056Jrg | MGI:3579158
Name: transgene insertion 42-056, Joachim R Gothert
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Genotype
Genotype
Symbol: Tal1/Tal1
Background: involves: 129S4/SvJae
Zygosity: hm
Has Mutant Allele: true
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Publication
1763056 | J:19155
First Author: Xia Y
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia.
Volume: 88
Issue: 24
Pages: 11416-20
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HT Experiment
GSE165402 | The migratory pathways of the cells that form the endocardium, dorsal aortae, and head vasculature in the mouse embryo
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Strain
MGI:7316478 | C57BL/6-Tg(Tal1-cre/ERT)42-056Jrg/J
Attribute String: coisogenic, mutant strain, transgenic
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Allele
Tal1<tm1Wehi> | MGI:1857566
Name: T cell acute lymphocytic leukemia 1; targeted mutation 1, Walter and Eliza Hall Institute of Medical Research
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Tg(Tal1-cre/ERT)1Jrg | MGI:3055721
Name: transgene insertion 1, Joachim R Gothert
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Allele
Tg(Lck-Tal1)#Led | MGI:3528075
Name: transgene insertion, Philip Leder
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:7549074 | C57BL/6J-Rps12<em1Nbakr> Tg(Tal1-cre/ERT)42-056Jrg
Attribute String: coisogenic, mutant strain, transgenic, endonuclease-mediated mutation
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Publication
27797340 | J:239696
First Author: Gu H
Year: 2016
Journal: J Clin Invest
Title: Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis.
Volume: 126
Issue: 12
Pages: 4537-4553
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Genotype
Genotype
Symbol: Rps12/Rps12 Tg(Tal1-cre/ERT)42-056Jrg/?
Background: C57BL/6J-Rps12 Tg(Tal1-cre/ERT)42-056Jrg
Zygosity: cn
Has Mutant Allele: true
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Publication
1528853 | J:2496
First Author: Brown L
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: HEN1 and HEN2: a subgroup of basic helix-loop-helix genes that are coexpressed in a human neuroblastoma.
Volume: 89
Issue: 18
Pages: 8492-6
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Protein
A2AD40
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: true
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Publication
1396592 | -
First Author: Aplan PD
Year: 1992
Journal: EMBO J
Title: The SCL gene product: a positive regulator of erythroid differentiation.
Volume: 11
Issue: 11
Pages: 4073-81
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Publication
1328219 | J:21702
First Author: Lipkowitz S
Year: 1992
Journal: J Biol Chem
Title: A comparative structural characterization of the human NSCL-1 and NSCL-2 genes. Two basic helix-loop-helix genes expressed in the developing nervous system.
Volume: 267
Issue: 29
Pages: 21065-71
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Publication
2752424 | -
First Author: Mellentin JD
Year: 1989
Journal: Cell
Title: lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif.
Volume: 58
Issue: 1
Pages: 77-83
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Protein Domain
IPR040238 | TAL-like
Type: Family
Description: This entry includes highly related proteins with a Myc-type, basic helix-loop-helix (bHLH) domain, including T-cell acute lymphocytic leukemia proteins 1 and 2 (TAL1 and TAL2), helix-loop-helix proteins 1 and 2 (NHLH1/HEN1 and NHLH2/HEN2), and protein lyl-1 (LYL1). The bHLH domain is required for protein dimerization and DNA binding []. TAL1 may be a positive regulator of erythroid differentiation []. The TAL1 and TAL2 genes are altered in T-cell acute lymphoblastic leukemia []. The NHLH1 and NHLH2 genes are expressed in the developing nervous system, especially cell lines derived from neuroblastoma, PNET, and small cell lung cancer [], and the proteins may have regulatory functions in the developing nervous system []. LYL1 has a role in primitive erythropoiesis []. A chromosomal aberration involving the LYL1 gene may be a cause of a form of T-cell acute lymphoblastic leukemia [].
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Strain
MGI:7316480 | C57BL/6-Tg(Tal1-cre/ERT)1Jrg/J
Attribute String: coisogenic, mutant strain, transgenic
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Allele
Tg(Lck-Tal1)4709Led | MGI:3528080
Name: transgene insertion 4709, Philip Leder
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
24385538 | J:208691
First Author: Zheng J
Year: 2014
Journal: Blood
Title: Profilin 1 is essential for retention and metabolism of mouse hematopoietic stem cells in bone marrow.
Volume: 123
Issue: 7
Pages: 992-1001
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Genotype
Genotype
Symbol: Tal1/Tal1
Background: involves: 129S1/Sv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hif1a/Hif1a Tg(Tal1-cre/ERT)42-056Jrg/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Meis1/Meis1 Tg(Tal1-cre/ERT)42-056Jrg/?
Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tal1/Tal1<+>
Background: involves: 129S1/Sv * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tal1/Tal1
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Publication
18391070 | J:134671
First Author: Weis SM
Year: 2008
Journal: J Cell Biol
Title: Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK.
Volume: 181
Issue: 1
Pages: 43-50
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Publication
37272618 | J:338970
   
First Author: Folgado-Marco V
Year: 2023
Journal: Elife
Title: Haploinsufficiency of the essential gene Rps12 causes defects in erythropoiesis and hematopoietic stem cell maintenance.
Volume: 12
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Publication
26777415 | J:231316
First Author: Sun S
Year: 2015
Journal: Cancer Cell
Title: Constitutive Activation of mTORC1 in Endothelial Cells Leads to the Development and Progression of Lymphangiosarcoma through VEGF Autocrine Signaling.
Volume: 28
Issue: 6
Pages: 758-772
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Publication
26385351 | J:231110
First Author: Anderson H
Year: 2015
Journal: Blood
Title: Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression.
Volume: 126
Issue: 26
Pages: 2811-20
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Publication
23771883 | J:231253
First Author: Schmidt TT
Year: 2013
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Conditional deletion of FAK in mice endothelium disrupts lung vascular barrier function due to destabilization of RhoA and Rac1 activities.
Volume: 305
Issue: 4
Pages: L291-300
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Publication
25863249 | J:299573
First Author: Diebold I
Year: 2015
Journal: Cell Metab
Title: BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension.
Volume: 21
Issue: 4
Pages: 596-608
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Strain
MGI:3849579 | FVB/N-Tg(Lck-Tal1)4709Led
Attribute String: coisogenic, transgenic
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Publication
24394663 | J:208690
First Author: Roderick JE
Year: 2014
Journal: Blood
Title: c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells.
Volume: 123
Issue: 7
Pages: 1040-50
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Publication
35483374 | J:325686
First Author: Li X
Year: 2022
Journal: Cell
Title: Maladaptive innate immune training of myelopoiesis links inflammatory comorbidities.
Volume: 185
Issue: 10
Pages: 1709-1727.e18
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Allele
Gt(ROSA)26Sor<tm1(Tcfe2a/Tal1)Xhsu> | MGI:3833549
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Xiao-Hong Sun
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Genotype
Genotype
Symbol: Tg(Lck-Tal1)4709Led/?
Background: FVB/N-Tg(Lck-Tal1)4709Led
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Eng/Eng Tg(Tal1-cre/ERT)1Jrg/?
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Acvrl1/Acvrl1 Tg(Tal1-cre/ERT)1Jrg/?
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Tal1-cre/ERT)1Jrg/? Tsc1/Tsc1
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
GSE52126 | Global discovery of erythroid long non-coding RNAs reveals novel regulators of red cell maturation
Series Id: E-GEOD-52126
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
32541670 | J:291905
First Author: Vu T
Year: 2020
Journal: Nat Commun
Title: Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia.
Volume: 11
Issue: 1
Pages: 3021
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Publication
25578474 | J:221975
First Author: Forristal CE
Year: 2015
Journal: Leukemia
Title: HIF-1α is required for hematopoietic stem cell mobilization and 4-prolyl hydroxylase inhibitors enhance mobilization by stabilizing HIF-1α.
Volume: 29
Issue: 6
Pages: 1366-78
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Publication
30902969 | J:276744
First Author: Kelly MJ
Year: 2019
Journal: Nat Commun
Title: Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis.
Volume: 10
Issue: 1
Pages: 1347
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Strain
MGI:7413163 | B6.Cg-Srsf2<tm2874.1Arte> Gt(ROSA)26Sor<tm1(EYFP)Cos> Tg(Tal1-cre/ERT)42-056Jrg/Apb
Attribute String: mutant strain, targeted mutation, transgenic, congenic
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Publication
28057738 | J:314582
First Author: Cañete A
Year: 2017
Journal: Haematologica
Title: A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice.
Volume: 102
Issue: 4
Pages: 647-655
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Publication
36813768 | J:333477
First Author: Yang F
Year: 2023
Journal: Nat Commun
Title: Autophagy inhibition prevents lymphatic malformation progression to lymphangiosarcoma by decreasing osteopontin and Stat3 signaling.
Volume: 14
Issue: 1
Pages: 978
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Genotype
Genotype
Symbol: Jam3/Jam3 Tg(Tal1-cre/ERT)1Jrg/?
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
23642367 | J:317950
First Author: Chan SS
Year: 2013
Journal: Cell Stem Cell
Title: Mesp1 patterns mesoderm into cardiac, hematopoietic, or skeletal myogenic progenitors in a context-dependent manner.
Volume: 12
Issue: 5
Pages: 587-601
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Publication
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