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Search results 801 to 900 out of 2796 for Thy1

0.017s
Type Details Score
Publication
First Author: Sampson TR
Year: 2016
Journal: Cell
Title: Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease.
Volume: 167
Issue: 6
Pages: 1469-1480.e12
Publication
First Author: Chen M
Year: 2022
Journal: J Cell Mol Med
Title: Increase in membrane surface expression and phosphorylation of TRPC3 related to olfactory dysfunction in α-synuclein transgenic mice.
Volume: 26
Issue: 19
Pages: 5008-5020
Publication
First Author: Brekk OR
Year: 2018
Journal: Sci Rep
Title: Lipid-dependent deposition of alpha-synuclein and Tau on neuronal Secretogranin II-positive vesicular membranes with age.
Volume: 8
Issue: 1
Pages: 15207
Publication  
First Author: Betzer C
Year: 2018
Journal: EMBO Rep
Title: Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation.
Volume: 19
Issue: 5
Publication
First Author: Games D
Year: 2013
Journal: Am J Pathol
Title: Axonopathy in an α-synuclein transgenic model of Lewy body disease is associated with extensive accumulation of C-terminal-truncated α-synuclein.
Volume: 182
Issue: 3
Pages: 940-53
Publication  
First Author: Subramaniam SR
Year: 2018
Journal: Neurobiol Dis
Title: Chronic nicotine improves cognitive and social impairment in mice overexpressing wild type α-synuclein.
Volume: 117
Pages: 170-180
Publication
First Author: Bae EJ
Year: 2018
Journal: Nat Commun
Title: LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation.
Volume: 9
Issue: 1
Pages: 3465
Publication
First Author: Fleming SM
Year: 2006
Journal: Neuroscience
Title: Behavioral effects of dopaminergic agonists in transgenic mice overexpressing human wildtype alpha-synuclein.
Volume: 142
Issue: 4
Pages: 1245-53
Publication  
First Author: Siddu A
Year: 2020
Journal: Neurobiol Dis
Title: Beneficial effects of cysteamine in Thy1-α-Syn mice and induced pluripotent stem cells with a SNCA gene triplication.
Volume: 145
Pages: 105042
Publication
First Author: Shaltiel-Karyo R
Year: 2013
Journal: J Biol Chem
Title: A blood-brain barrier (BBB) disrupter is also a potent α-synuclein (α-syn) aggregation inhibitor: a novel dual mechanism of mannitol for the treatment of Parkinson disease (PD).
Volume: 288
Issue: 24
Pages: 17579-88
Publication
First Author: Games D
Year: 2014
Journal: J Neurosci
Title: Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models.
Volume: 34
Issue: 28
Pages: 9441-54
Publication    
First Author: Abdel-Haq R
Year: 2022
Journal: Elife
Title: A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice.
Volume: 11
Publication
First Author: Cartier AE
Year: 2012
Journal: PLoS One
Title: Differential effects of UCHL1 modulation on alpha-synuclein in PD-like models of alpha-synucleinopathy.
Volume: 7
Issue: 4
Pages: e34713
Publication
First Author: Leon J
Year: 2017
Journal: Cell Rep
Title: Peripheral Elevation of a Klotho Fragment Enhances Brain Function and Resilience in Young, Aging, and α-Synuclein Transgenic Mice.
Volume: 20
Issue: 6
Pages: 1360-1371
Publication  
First Author: El-Agnaf O
Year: 2017
Journal: Neurobiol Dis
Title: Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy.
Volume: 104
Pages: 85-96
Publication
First Author: Oh CK
Year: 2017
Journal: Cell Rep
Title: S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson's Disease Models.
Volume: 21
Issue: 8
Pages: 2171-2182
Publication  
First Author: Rocha EM
Year: 2015
Journal: Neurobiol Dis
Title: Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons.
Volume: 82
Pages: 495-503
Publication
First Author: McLean JR
Year: 2012
Journal: Mol Cell Neurosci
Title: Transcript expression levels of full-length alpha-synuclein and its three alternatively spliced variants in Parkinson's disease brain regions and in a transgenic mouse model of alpha-synuclein overexpression.
Volume: 49
Issue: 2
Pages: 230-9
Publication
First Author: Lassen LB
Year: 2018
Journal: PLoS One
Title: ELISA method to detect α-synuclein oligomers in cell and animal models.
Volume: 13
Issue: 4
Pages: e0196056
Publication
First Author: Dhungel N
Year: 2015
Journal: Neuron
Title: Parkinson's disease genes VPS35 and EIF4G1 interact genetically and converge on α-synuclein.
Volume: 85
Issue: 1
Pages: 76-87
Publication    
First Author: Sampson TR
Year: 2020
Journal: Elife
Title: A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice.
Volume: 9
Publication  
First Author: Bermúdez ML
Year: 2019
Journal: Neuroscience
Title: Evaluation of Carnosine Intervention in the Thy1-aSyn Mouse Model of Parkinson's Disease.
Volume: 411
Pages: 270-278
Publication  
First Author: Fleming SM
Year: 2013
Journal: Front Neurol
Title: Impaired baroreflex function in mice overexpressing alpha-synuclein.
Volume: 4
Pages: 103
Publication  
First Author: Moloney EB
Year: 2018
Journal: Neurobiol Dis
Title: The glycoprotein GPNMB is selectively elevated in the substantia nigra of Parkinson's disease patients and increases after lysosomal stress.
Volume: 120
Pages: 1-11
Publication  
First Author: Kim C
Year: 2015
Journal: J Neuroinflammation
Title: Hypoestoxide reduces neuroinflammation and α-synuclein accumulation in a mouse model of Parkinson's disease.
Volume: 12
Pages: 236
Publication  
First Author: Gerstenberger J
Year: 2016
Journal: Behav Brain Res
Title: The novel adaptive rotating beam test unmasks sensorimotor impairments in a transgenic mouse model of Parkinson's disease.
Volume: 304
Pages: 102-10
Publication
First Author: Trudler D
Year: 2021
Journal: J Neurosci
Title: α-Synuclein Oligomers Induce Glutamate Release from Astrocytes and Excessive Extrasynaptic NMDAR Activity in Neurons, Thus Contributing to Synapse Loss.
Volume: 41
Issue: 10
Pages: 2264-2273
Publication  
First Author: Kim YC
Year: 2017
Journal: Front Neurol
Title: RNA Interference of Human α-Synuclein in Mouse.
Volume: 8
Pages: 13
Publication
First Author: Watson MB
Year: 2012
Journal: Exp Neurol
Title: Regionally-specific microglial activation in young mice over-expressing human wildtype alpha-synuclein.
Volume: 237
Issue: 2
Pages: 318-34
Publication
First Author: Yan R
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson's disease and DLB.
Volume: 115
Issue: 51
Pages: E12053-E12062
Publication  
First Author: Reimer L
Year: 2018
Journal: Neurobiol Dis
Title: Inflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell death.
Volume: 115
Pages: 17-28
Publication  
First Author: Delenclos M
Year: 2014
Journal: Neuroscience
Title: Immunolocalization of human alpha-synuclein in the Thy1-aSyn ("Line 61") transgenic mouse line.
Volume: 277
Pages: 647-64
Publication  
First Author: Schommer J
Year: 2018
Journal: Front Neurosci
Title: Palmitic Acid-Enriched Diet Increases α-Synuclein and Tyrosine Hydroxylase Expression Levels in the Mouse Brain.
Volume: 12
Pages: 552
Publication
First Author: Chesselet MF
Year: 2012
Journal: Neurotherapeutics
Title: A progressive mouse model of Parkinson's disease: the Thy1-aSyn ("Line 61") mice.
Volume: 9
Issue: 2
Pages: 297-314
Allele
Name: transgene insertion 5, Simon Rumpel
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 6, Simon Rumpel
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 41, Eliezer Masliah
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Rodriguez-Ortiz CJ
Year: 2013
Journal: Am J Pathol
Title: Neuronal-specific overexpression of a mutant valosin-containing protein associated with IBMPFD promotes aberrant ubiquitin and TDP-43 accumulation and cognitive dysfunction in transgenic mice.
Volume: 183
Issue: 2
Pages: 504-15
Publication
First Author: Rieker C
Year: 2011
Journal: PLoS One
Title: Neuropathology in mice expressing mouse alpha-synuclein.
Volume: 6
Issue: 9
Pages: e24834
Allele
Name: transgene insertion GP4.12, Douglas Kim
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 19, Vladimir L Buchman
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion GP4.6, Douglas Kim
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion GP5.1, Douglas Kim
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion GP5.3, Douglas Kim
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion GP5.12, Douglas Kim
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion GP2.11, Douglas Kim
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 13, Eliezer Masliah
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion 16, Eliezer Masliah
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion C,William Van Nostrand
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence, Reporter
Allele
Name: transgene insertion W7, Joshua R Sanes
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: coisogenic, mutant strain, transgenic
Publication
First Author: Nuber S
Year: 2021
Journal: Ann Neurol
Title: A Stearoyl-Coenzyme A Desaturase Inhibitor Prevents Multiple Parkinson Disease Phenotypes in α-Synuclein Mice.
Volume: 89
Issue: 1
Pages: 74-90
Allele
Name: transgene insertion, Yoshio Tsuboi
Allele Type: Transgenic
Attribute String: Epitope tag, Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion 19, Z David Luo
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 27, Krzysztof Kucharz
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 5-40, Scott Wilson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Ann Marie Craig
Allele Type: Transgenic
Attribute String: Epitope tag, Inserted expressed sequence
Strain
Attribute String: mutant strain, transgenic
Genotype
Symbol: Tg(Thy1-Fcer2a)2431Putt/?
Background: involves: BALB/c * C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Thy1-Fcer2a)2733Putt/?
Background: involves: BALB/c * C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(THY1-Snca)M2mSud/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Thy1-TARDBP)6Singh/Tg(Thy1-TARDBP)6Singh
Background: involves: C57BL/6 * C57BL/6J * SJL
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Thy1-SNCA)61Ema/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Thy1-VCP*A232E)BMaki/?
Background: involves: C57BL/6J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Thy1-Snca)1S13Putt/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Teichmann LL
Year: 2012
Journal: J Immunol
Title: B cell-derived IL-10 does not regulate spontaneous systemic autoimmunity in MRL.Fas(lpr) mice.
Volume: 188
Issue: 2
Pages: 678-85
Publication  
First Author: Khan AR
Year: 2015
Journal: Nat Commun
Title: PD-L1hi B cells are critical regulators of humoral immunity.
Volume: 6
Pages: 5997
Publication
First Author: Kuhn C
Year: 2017
Journal: J Immunol
Title: IL-6 Inhibits Upregulation of Membrane-Bound TGF-β 1 on CD4+ T Cells and Blocking IL-6 Enhances Oral Tolerance.
Volume: 198
Issue: 3
Pages: 1202-1209
Publication    
First Author: Clement M
Year: 2023
Journal: Elife
Title: Inhibitory IL-10-producing CD4(+) T cells are T-bet-dependent and facilitate cytomegalovirus persistence via coexpression of arginase-1.
Volume: 12
Publication
First Author: Maynard CL
Year: 2009
Journal: J Exp Med
Title: Contrasting roles for all-trans retinoic acid in TGF-beta-mediated induction of Foxp3 and Il10 genes in developing regulatory T cells.
Volume: 206
Issue: 2
Pages: 343-57
Allele
Name: transgene insertion 39, Eric K Richfield
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Ezzi SA
Year: 2010
Journal: J Neurochem
Title: Neuronal over-expression of chromogranin A accelerates disease onset in a mouse model of ALS.
Volume: 115
Issue: 5
Pages: 1102-11
Publication
First Author: Probst A
Year: 2000
Journal: Acta Neuropathol
Title: Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein.
Volume: 99
Issue: 5
Pages: 469-81
Publication
First Author: Hsieh S
Year: 2000
Journal: Mol Immunol
Title: Transgenic mice expressing surface markers for IFN-gamma and IL-4 producing cells.
Volume: 37
Issue: 6
Pages: 281-93
Publication
First Author: Wang L
Year: 2008
Journal: Neuroreport
Title: Abnormal colonic motility in mice overexpressing human wild-type alpha-synuclein.
Volume: 19
Issue: 8
Pages: 873-6
Publication
First Author: Eede P
Year: 2020
Journal: EMBO Rep
Title: Interleukin-12/23 deficiency differentially affects pathology in male and female Alzheimer's disease-like mice.
Volume: 21
Issue: 3
Pages: e48530
Publication
First Author: Rolyan H
Year: 2011
Journal: Brain
Title: Telomere shortening reduces Alzheimer's disease amyloid pathology in mice.
Volume: 134
Issue: Pt 7
Pages: 2044-56
Allele
Name: transgene insertion 18, Philipp J Kahle
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Liu Q
Year: 2007
Journal: FASEB J
Title: Dissecting the signaling pathway of nicotine-mediated neuroprotection in a mouse Alzheimer disease model.
Volume: 21
Issue: 1
Pages: 61-73
Strain
Attribute String: mutant strain, transgenic
Strain
Attribute String: mutant strain, transgenic, congenic
Publication
First Author: Roder S
Year: 2003
Journal: Neuroscience
Title: Electrophysiological studies on the hippocampus and prefrontal cortex assessing the effects of amyloidosis in amyloid precursor protein 23 transgenic mice.
Volume: 120
Issue: 3
Pages: 705-20
Publication  
First Author: Senechal Y
Year: 2008
Journal: Brain Res
Title: Increased exploratory activity of APP23 mice in a novel environment is reversed by siRNA.
Volume: 1243
Pages: 124-33
Publication
First Author: Van Dam D
Year: 2003
Journal: Eur J Neurosci
Title: Age-dependent cognitive decline in the APP23 model precedes amyloid deposition.
Volume: 17
Issue: 2
Pages: 388-96
Publication
First Author: Paganetti P
Year: 2013
Journal: Neurobiol Aging
Title: Transgenic expression of β1 antibody in brain neurons impairs age-dependent amyloid deposition in APP23 mice.
Volume: 34
Issue: 12
Pages: 2866-78
Publication
First Author: Meyer-Luehmann M
Year: 2006
Journal: Science
Title: Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host.
Volume: 313
Issue: 5794
Pages: 1781-4
Publication  
First Author: Leshchyns'ka I
Year: 2015
Journal: Nat Commun
Title: Aβ-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer's disease.
Volume: 6
Pages: 8836
Publication
First Author: Calhoun ME
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid.
Volume: 96
Issue: 24
Pages: 14088-93
Publication
First Author: Middei S
Year: 2010
Journal: Learn Mem
Title: Learning discloses abnormal structural and functional plasticity at hippocampal synapses in the APP23 mouse model of Alzheimer's disease.
Volume: 17
Issue: 5
Pages: 236-40
Publication
First Author: Wolf SA
Year: 2006
Journal: Biol Psychiatry
Title: Cognitive and physical activity differently modulate disease progression in the amyloid precursor protein (APP)-23 model of Alzheimer's disease.
Volume: 60
Issue: 12
Pages: 1314-23
Publication
First Author: Frank S
Year: 2008
Journal: Glia
Title: TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice.
Volume: 56
Issue: 13
Pages: 1438-47
Publication  
First Author: Hendrickx JO
Year: 2021
Journal: Int J Mol Sci
Title: Serum Corticosterone and Insulin Resistance as Early Biomarkers in the hAPP23 Overexpressing Mouse Model of Alzheimer's Disease.
Volume: 22
Issue: 13
Publication
First Author: Prut L
Year: 2007
Journal: Behav Brain Res
Title: Aged APP23 mice show a delay in switching to the use of a strategy in the Barnes maze.
Volume: 179
Issue: 1
Pages: 107-10
Publication
First Author: Diez M
Year: 2003
Journal: Neurobiol Dis
Title: Neuropeptide alterations in the hippocampal formation and cortex of transgenic mice overexpressing beta-amyloid precursor protein (APP) with the Swedish double mutation (APP23).
Volume: 14
Issue: 3
Pages: 579-94
Publication
First Author: Mueggler T
Year: 2003
Journal: J Neurosci
Title: Age-dependent impairment of somatosensory response in the amyloid precursor protein 23 transgenic mouse model of Alzheimer's disease.
Volume: 23
Issue: 23
Pages: 8231-6
Publication
First Author: Hellweg R
Year: 2006
Journal: Learn Mem
Title: Spatial navigation in complex and radial mazes in APP23 animals and neurotrophin signaling as a biological marker of early impairment.
Volume: 13
Issue: 1
Pages: 63-71
Publication
First Author: Beckmann N
Year: 2003
Journal: J Neurosci
Title: Age-dependent cerebrovascular abnormalities and blood flow disturbances in APP23 mice modeling Alzheimer's disease.
Volume: 23
Issue: 24
Pages: 8453-9
Publication
First Author: Heneka MT
Year: 2006
Journal: J Neurosci
Title: Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice.
Volume: 26
Issue: 5
Pages: 1343-54
Publication
First Author: Jiang H
Year: 2014
Journal: Hum Mol Genet
Title: Genetic deletion of TNFRII gene enhances the Alzheimer-like pathology in an APP transgenic mouse model via reduction of phosphorylated IκBα.
Volume: 23
Issue: 18
Pages: 4906-18
Publication
First Author: Stöhr J
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice.
Volume: 111
Issue: 28
Pages: 10329-34