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Search results 801 to 874 out of 874 for Trpv4

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Type Details Score
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
33624376 | J:355754
First Author: Redmon SN
Year: 2021
Journal: Glia
Title: TRPV4 channels mediate the mechanoresponse in retinal microglia.
Volume: 69
Issue: 6
Pages: 1563-1582
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Publication
26973533 | J:247487
 
First Author: Gu QD
Year: 2016
Journal: Front Physiol
Title: Activation of TRPV4 Regulates Respiration through Indirect Activation of Bronchopulmonary Sensory Neurons.
Volume: 7
Pages: 65
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Publication
31387748 | J:291721
First Author: Das R
Year: 2019
Journal: Biochem Biophys Res Commun
Title: TRPV4 expresses in bone cell lineages and TRPV4-R616Q mutant causing Brachyolmia in human reveals "loss-of-interaction" with cholesterol.
Volume: 517
Issue: 4
Pages: 566-574
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DO Term
DOID:0110182 | Charcot-Marie-Tooth disease axonal type 2C
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Publication
22328087 | -
First Author: Lanciotti A
Year: 2012
Journal: Hum Mol Genet
Title: Megalencephalic leukoencephalopathy with subcortical cysts protein 1 functionally cooperates with the TRPV4 cation channel to activate the response of astrocytes to osmotic stress: dysregulation by pathological mutations.
Volume: 21
Issue: 10
Pages: 2166-80
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Allele
Trpv4<em1Smoc> | MGI:7293011
Name: transient receptor potential cation channel, subfamily V, member 4; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Publication
16368742 | -
First Author: Xu H
Year: 2006
Journal: Am J Physiol Renal Physiol
Title: Glycosylation of the osmoresponsive transient receptor potential channel TRPV4 on Asn-651 influences membrane trafficking.
Volume: 290
Issue: 5
Pages: F1103-9
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Publication
20043876 | -
First Author: Peng H
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Identification of a Protein Kinase C-dependent phosphorylation site involved in sensitization of TRPV4 channel.
Volume: 391
Issue: 4
Pages: 1721-5
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Publication
17932042 | -
First Author: Wang Y
Year: 2007
Journal: J Biol Chem
Title: OS-9 regulates the transit and polyubiquitination of TRPV4 in the endoplasmic reticulum.
Volume: 282
Issue: 50
Pages: 36561-70
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Allele
Tg(Tyr,Col2a1-Trpv4*R594H)#Dhco | MGI:5788532
Name: transgene insertion, Daniel H Cohn
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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DO Term
DOID:0111215 | autosomal dominant distal hereditary motor neuronopathy 8
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DO Term
DOID:0111554 | spondylometaphyseal dysplasia Kozlowski type
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DO Term
DOID:0111514 | metatropic dysplasia
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DO Term
DOID:0111552 | scapuloperoneal spinal muscular atrophy
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DO Term
DOID:0111539 | parastremmatic dwarfism
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DO Term
DOID:0111553 | spondyloepiphyseal dysplasia Maroteaux type
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Gene
54332 | GDAP1
Type: gene
Organism: human
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Allele
Tg(Trpv4-EGFP)MT43Gsat | MGI:4847512
Name: transgene insertion MT43, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:5818236 | C57BL/6N-Trpv4<em1(cre/ERT2)Amc>/J
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Trpv4<em1Dhco> | MGI:7861782
Name: transient receptor potential cation channel, subfamily V, member 4; endonuclease-mediated mutation 1, Daniel H Cohn
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, Humanized sequence
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Genotype
Genotype
Symbol: Tg(Tyr,Col2a1-Trpv4*R594H)#Dhco/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Strain
MGI:5004224 | STOCK Tg(Trpv4-EGFP)MT43Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Strain
MGI:7861783 | C57BL/6J-Trpv4<em1Dhco>/J
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Tg(Myh6-mCherry,-Trpv4)1Td | MGI:7593922
Name: transgene insertion 1, Timothy Domeier
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Protein
Q8VHK5
Organism: Mus musculus/domesticus
Length: 382  
Fragment?: false
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Protein
E9QP87
Organism: Mus musculus/domesticus
Length: 388  
Fragment?: false
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Protein
Q8BLR0
Organism: Mus musculus/domesticus
Length: 382  
Fragment?: false
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Protein
Q80U92
Organism: Mus musculus/domesticus
Length: 423  
Fragment?: true
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Publication
25883547 | -
 
First Author: Brignone MS
Year: 2015
Journal: Front Cell Neurosci
Title: MLC1 protein: a likely link between leukodystrophies and brain channelopathies.
Volume: 9
Pages: 66
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Publication
20926452 | -
First Author: Brignone MS
Year: 2011
Journal: Hum Mol Genet
Title: The beta1 subunit of the Na,K-ATPase pump interacts with megalencephalic leucoencephalopathy with subcortical cysts protein 1 (MLC1) in brain astrocytes: new insights into MLC pathogenesis.
Volume: 20
Issue: 1
Pages: 90-103
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Publication
24561067 | -
 
First Author: Brignone MS
Year: 2014
Journal: Neurobiol Dis
Title: Megalencephalic leukoencephalopathy with subcortical cysts protein-1 modulates endosomal pH and protein trafficking in astrocytes: relevance to MLC disease pathogenesis.
Volume: 66
Pages: 1-18
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Protein Domain
IPR033280 | Membrane_MLC1
Type: Family
Description: MLC1 is a membrane protein, mainly expressed in brain astrocytes, that plays a role in astrocyte osmo-homeostasis []. Mutations in the MLC1 gene are linked to a rare leukodystrophy known as megalencephalic leukoencephalopathy with subcortical cysts (MLC). Several studies suggest that MLC1 plays a role in the regulation of ion and water fluxes and cell volume, but its exact function is not known []. It binds the beta-1 subunit of the Na,K-ATPase enzyme [], and interacts with the calcium permeable channel TRPV4 []and the vacuolar ATPase (V-ATPase) [].
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Strain
MGI:6159642 | B6.Cg-Trpv4<em1(cre/ERT2)Amc> Gt(ROSA)26Sor<tm1Sor>
Attribute String: congenic, mutant strain, targeted mutation, endonuclease-mediated mutation
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Strain
MGI:6348183 | B6.Cg-Tg(Myh6-mCherry,-Trpv4)1Td/Mmmh
Attribute String: transgenic, congenic, mutant strain
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Trpv4/Trpv4<+>
Background: B6.Cg-Trpv4 Gt(ROSA)26Sor
Zygosity: cn
Has Mutant Allele: true
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Publication
30995477 | J:284419
First Author: Rayees S
Year: 2019
Journal: Cell Rep
Title: PAR2-Mediated cAMP Generation Suppresses TRPV4-Dependent Ca2+ Signaling in Alveolar Macrophages to Resolve TLR4-Induced Inflammation.
Volume: 27
Issue: 3
Pages: 793-805.e4
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Publication
25713995 | J:321458
First Author: Sappington RM
Year: 2015
Journal: Channels (Austin)
Title: Activation of transient receptor potential vanilloid-1 (TRPV1) influences how retinal ganglion cell neurons respond to pressure-related stress.
Volume: 9
Issue: 2
Pages: 102-13
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Publication
36690845 | J:344531
First Author: Yamanoi Y
Year: 2023
Journal: Commun Biol
Title: TRPV3-ANO1 interaction positively regulates wound healing in keratinocytes.
Volume: 6
Issue: 1
Pages: 88
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Publication
21146788 | J:167037
First Author: Donkó A
Year: 2010
Journal: Free Radic Biol Med
Title: Urothelial cells produce hydrogen peroxide through the activation of Duox1.
Volume: 49
Issue: 12
Pages: 2040-8
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Publication
36070688 | J:328552
First Author: Caires R
Year: 2022
Journal: Cell Rep
Title: Genetic- and diet-induced ω-3 fatty acid enrichment enhances TRPV4-mediated vasodilation in mice.
Volume: 40
Issue: 10
Pages: 111306
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Publication
15194687 | J:92550
First Author: Hu HZ
Year: 2004
Journal: J Biol Chem
Title: 2-aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3.
Volume: 279
Issue: 34
Pages: 35741-8
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Publication
27913425 | J:238785
First Author: Suresh K
Year: 2017
Journal: Am J Physiol Lung Cell Mol Physiol
Title: CD36 mediates H2O2-induced calcium influx in lung microvascular endothelial cells.
Volume: 312
Issue: 1
Pages: L143-L153
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Publication
30848676 | J:272385
     
First Author: Collier DM
Year: 2019
Journal: Am J Physiol Heart Circ Physiol
Title: Extracellular histones induce calcium signals in the endothelium of resistance-sized mesenteric arteries and cause loss of endothelium-dependent dilation.
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Publication
18268148 | J:148452
First Author: Saliez J
Year: 2008
Journal: Circulation
Title: Role of caveolar compartmentation in endothelium-derived hyperpolarizing factor-mediated relaxation: Ca2+ signals and gap junction function are regulated by caveolin in endothelial cells.
Volume: 117
Issue: 8
Pages: 1065-74
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Publication
31150667 | J:309081
 
First Author: Sakuta H
Year: 2020
Journal: Neurosci Res
Title: Nax-positive glial cells in the organum vasculosum laminae terminalis produce epoxyeicosatrienoic acids to induce water intake in response to increases in [Na+] in body fluids.
Volume: 154
Pages: 45-51
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Publication
26945080 | J:233007
First Author: Yap FC
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: Endothelial SK3 channel-associated Ca2+ microdomains modulate blood pressure.
Volume: 310
Issue: 9
Pages: H1151-63
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Publication
25564678 | J:259447
First Author: Sullivan MN
Year: 2015
Journal: Sci Signal
Title: Localized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilation.
Volume: 8
Issue: 358
Pages: ra2
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Publication
24495803 | J:218579
First Author: Jablonski CL
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Integrin α1β1 participates in chondrocyte transduction of osmotic stress.
Volume: 445
Issue: 1
Pages: 184-90
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Publication
29037241 | J:321381
First Author: Yi M
Year: 2017
Journal: J Neuroinflammation
Title: The potassium channel KCa3.1 constitutes a pharmacological target for astrogliosis associated with ischemia stroke.
Volume: 14
Issue: 1
Pages: 203
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Publication
31866822 | J:288857
 
First Author: Wang S
Year: 2019
Journal: Front Mol Neurosci
Title: Transient Receptor Potential Cation Channel Subfamily Vanilloid 4 and 3 in the Inner Ear Protect Hearing in Mice.
Volume: 12
Pages: 296
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Publication
26019339 | J:222239
First Author: Kim KJ
Year: 2015
Journal: J Neurosci
Title: Astrocyte contributions to flow/pressure-evoked parenchymal arteriole vasoconstriction.
Volume: 35
Issue: 21
Pages: 8245-57
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Publication
25903376 | J:243253
First Author: Majhi RK
Year: 2015
Journal: FEBS J
Title: Functional expression of TRPV channels in T cells and their implications in immune regulation.
Volume: 282
Issue: 14
Pages: 2661-81
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Publication
25914628 | J:321368
 
First Author: Jie P
Year: 2015
Journal: Front Cell Neurosci
Title: Blockage of transient receptor potential vanilloid 4 inhibits brain edema in middle cerebral artery occlusion mice.
Volume: 9
Pages: 141
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Publication
38568964 | J:354616
First Author: Garrud TAC
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: WNK kinase is a vasoactive chloride sensor in endothelial cells.
Volume: 121
Issue: 15
Pages: e2322135121
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Publication
37963195 | J:354785
First Author: Mata-Daboin A
Year: 2023
Journal: Sci Signal
Title: Vasodilators activate the anion channel TMEM16A in endothelial cells to reduce blood pressure.
Volume: 16
Issue: 811
Pages: eadh9399
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Publication
32178446 | J:298458
 
First Author: Kogiso H
Year: 2020
Journal: Int J Mol Sci
Title: Airway Ciliary Beating Affected by the Pcp4 Dose-Dependent [Ca2+]i Increase in Down Syndrome Mice, Ts1Rhr.
Volume: 21
Issue: 6
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Publication
35432302 | J:323919
 
First Author: Yarishkin O
Year: 2022
Journal: Front Immunol
Title: Emergent Temporal Signaling in Human Trabecular Meshwork Cells: Role of TRPV4-TRPM4 Interactions.
Volume: 13
Pages: 805076
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Publication
28111539 | J:247526
 
First Author: Ritter KE
Year: 2016
Journal: Front Neurosci
Title: Dynamic Expression of Serotonin Receptor 5-HT3A in Developing Sensory Innervation of the Lower Urinary Tract.
Volume: 10
Pages: 592
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Publication
30118343 | J:272447
First Author: Diaz-Otero JM
Year: 2018
Journal: Am J Physiol Heart Circ Physiol
Title: Mineralocorticoid receptor antagonism improves parenchymal arteriole dilation via a TRPV4-dependent mechanism and prevents cognitive dysfunction in hypertension.
Volume: 315
Issue: 5
Pages: H1304-H1315
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Publication
28122715 | J:309794
First Author: Siroky BJ
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: Primary cilia regulate the osmotic stress response of renal epithelial cells through TRPM3.
Volume: 312
Issue: 4
Pages: F791-F805
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Publication
33122390 | J:297669
First Author: Turovsky EA
Year: 2020
Journal: J Neurosci
Title: Mechanosensory Signaling in Astrocytes.
Volume: 40
Issue: 49
Pages: 9364-9371
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Publication
26840527 | J:256657
First Author: Sonkusare SK
Year: 2016
Journal: J Physiol
Title: Inward rectifier potassium (Kir2.1) channels as end-stage boosters of endothelium-dependent vasodilators.
Volume: 594
Issue: 12
Pages: 3271-85
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Publication
30974795 | J:290976
 
First Author: Kameda T
Year: 2019
Journal: Int J Mol Sci
Title: Expression and Activity of TRPA1 and TRPV1 in the Intervertebral Disc: Association with Inflammation and Matrix Remodeling.
Volume: 20
Issue: 7
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Publication
34320366 | J:316112
First Author: Wong NR
Year: 2021
Journal: Immunity
Title: Resident cardiac macrophages mediate adaptive myocardial remodeling.
Volume: 54
Issue: 9
Pages: 2072-2088.e7
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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