|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 801 to 874 out of 874 for Trpv4

<< First    < Previous  |  Next >    Last >>
0.014s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Publication
33624376 | J:355754
First Author: Redmon SN
Year: 2021
Journal: Glia
Title: TRPV4 channels mediate the mechanoresponse in retinal microglia.
Volume: 69
Issue: 6
Pages: 1563-1582
•
•
•
•
•
Publication
26973533 | J:247487
 
First Author: Gu QD
Year: 2016
Journal: Front Physiol
Title: Activation of TRPV4 Regulates Respiration through Indirect Activation of Bronchopulmonary Sensory Neurons.
Volume: 7
Pages: 65
•
•
•
•
•
Publication
31387748 | J:291721
First Author: Das R
Year: 2019
Journal: Biochem Biophys Res Commun
Title: TRPV4 expresses in bone cell lineages and TRPV4-R616Q mutant causing Brachyolmia in human reveals "loss-of-interaction" with cholesterol.
Volume: 517
Issue: 4
Pages: 566-574
•
•
•
•
•
DO Term
DOID:0110182 | Charcot-Marie-Tooth disease axonal type 2C
•
•
•
•
•
Publication
22328087 | -
First Author: Lanciotti A
Year: 2012
Journal: Hum Mol Genet
Title: Megalencephalic leukoencephalopathy with subcortical cysts protein 1 functionally cooperates with the TRPV4 cation channel to activate the response of astrocytes to osmotic stress: dysregulation by pathological mutations.
Volume: 21
Issue: 10
Pages: 2166-80
•
•
•
•
•
Allele
Trpv4<em1Smoc> | MGI:7293011
Name: transient receptor potential cation channel, subfamily V, member 4; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Publication
16368742 | -
First Author: Xu H
Year: 2006
Journal: Am J Physiol Renal Physiol
Title: Glycosylation of the osmoresponsive transient receptor potential channel TRPV4 on Asn-651 influences membrane trafficking.
Volume: 290
Issue: 5
Pages: F1103-9
•
•
•
•
•
Publication
20043876 | -
First Author: Peng H
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Identification of a Protein Kinase C-dependent phosphorylation site involved in sensitization of TRPV4 channel.
Volume: 391
Issue: 4
Pages: 1721-5
•
•
•
•
•
Publication
17932042 | -
First Author: Wang Y
Year: 2007
Journal: J Biol Chem
Title: OS-9 regulates the transit and polyubiquitination of TRPV4 in the endoplasmic reticulum.
Volume: 282
Issue: 50
Pages: 36561-70
•
•
•
•
•
Allele
Tg(Tyr,Col2a1-Trpv4*R594H)#Dhco | MGI:5788532
Name: transgene insertion, Daniel H Cohn
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
DO Term
DOID:0111215 | autosomal dominant distal hereditary motor neuronopathy 8
•
•
•
•
•
DO Term
DOID:0111554 | spondylometaphyseal dysplasia Kozlowski type
•
•
•
•
•
DO Term
DOID:0111514 | metatropic dysplasia
•
•
•
•
•
DO Term
DOID:0111552 | scapuloperoneal spinal muscular atrophy
•
•
•
•
•
DO Term
DOID:0111539 | parastremmatic dwarfism
•
•
•
•
•
DO Term
DOID:0111553 | spondyloepiphyseal dysplasia Maroteaux type
•
•
•
•
•
Gene
54332 | GDAP1
Type: gene
Organism: human
•
•
•
•
•
Allele
Tg(Trpv4-EGFP)MT43Gsat | MGI:4847512
Name: transgene insertion MT43, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
•
•
•
•
•
Strain
MGI:5818236 | C57BL/6N-Trpv4<em1(cre/ERT2)Amc>/J
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•
Allele
Trpv4<em1Dhco> | MGI:7861782
Name: transient receptor potential cation channel, subfamily V, member 4; endonuclease-mediated mutation 1, Daniel H Cohn
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, Humanized sequence
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Tyr,Col2a1-Trpv4*R594H)#Dhco/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Strain
MGI:5004224 | STOCK Tg(Trpv4-EGFP)MT43Gsat/Mmucd
Attribute String: mutant stock, transgenic
•
•
•
•
•
Strain
MGI:7861783 | C57BL/6J-Trpv4<em1Dhco>/J
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Allele
Tg(Myh6-mCherry,-Trpv4)1Td | MGI:7593922
Name: transgene insertion 1, Timothy Domeier
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
•
•
•
•
•
Protein
Q8VHK5
Organism: Mus musculus/domesticus
Length: 382  
Fragment?: false
•
•
•
•
•
Protein
E9QP87
Organism: Mus musculus/domesticus
Length: 388  
Fragment?: false
•
•
•
•
•
Protein
Q8BLR0
Organism: Mus musculus/domesticus
Length: 382  
Fragment?: false
•
•
•
•
•
Protein
Q80U92
Organism: Mus musculus/domesticus
Length: 423  
Fragment?: true
•
•
•
•
•
Publication
25883547 | -
 
First Author: Brignone MS
Year: 2015
Journal: Front Cell Neurosci
Title: MLC1 protein: a likely link between leukodystrophies and brain channelopathies.
Volume: 9
Pages: 66
•
•
•
•
•
Publication
20926452 | -
First Author: Brignone MS
Year: 2011
Journal: Hum Mol Genet
Title: The beta1 subunit of the Na,K-ATPase pump interacts with megalencephalic leucoencephalopathy with subcortical cysts protein 1 (MLC1) in brain astrocytes: new insights into MLC pathogenesis.
Volume: 20
Issue: 1
Pages: 90-103
•
•
•
•
•
Publication
24561067 | -
 
First Author: Brignone MS
Year: 2014
Journal: Neurobiol Dis
Title: Megalencephalic leukoencephalopathy with subcortical cysts protein-1 modulates endosomal pH and protein trafficking in astrocytes: relevance to MLC disease pathogenesis.
Volume: 66
Pages: 1-18
•
•
•
•
•
Protein Domain
IPR033280 | Membrane_MLC1
Type: Family
Description: MLC1 is a membrane protein, mainly expressed in brain astrocytes, that plays a role in astrocyte osmo-homeostasis []. Mutations in the MLC1 gene are linked to a rare leukodystrophy known as megalencephalic leukoencephalopathy with subcortical cysts (MLC). Several studies suggest that MLC1 plays a role in the regulation of ion and water fluxes and cell volume, but its exact function is not known []. It binds the beta-1 subunit of the Na,K-ATPase enzyme [], and interacts with the calcium permeable channel TRPV4 []and the vacuolar ATPase (V-ATPase) [].
•
•
•
•
•
Strain
MGI:6159642 | B6.Cg-Trpv4<em1(cre/ERT2)Amc> Gt(ROSA)26Sor<tm1Sor>
Attribute String: congenic, mutant strain, targeted mutation, endonuclease-mediated mutation
•
•
•
•
•
Strain
MGI:6348183 | B6.Cg-Tg(Myh6-mCherry,-Trpv4)1Td/Mmmh
Attribute String: transgenic, congenic, mutant strain
•
•
•
•
•
Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Trpv4/Trpv4<+>
Background: B6.Cg-Trpv4 Gt(ROSA)26Sor
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Publication
30995477 | J:284419
First Author: Rayees S
Year: 2019
Journal: Cell Rep
Title: PAR2-Mediated cAMP Generation Suppresses TRPV4-Dependent Ca2+ Signaling in Alveolar Macrophages to Resolve TLR4-Induced Inflammation.
Volume: 27
Issue: 3
Pages: 793-805.e4
•
•
•
•
•
Publication
25713995 | J:321458
First Author: Sappington RM
Year: 2015
Journal: Channels (Austin)
Title: Activation of transient receptor potential vanilloid-1 (TRPV1) influences how retinal ganglion cell neurons respond to pressure-related stress.
Volume: 9
Issue: 2
Pages: 102-13
•
•
•
•
•
Publication
36690845 | J:344531
First Author: Yamanoi Y
Year: 2023
Journal: Commun Biol
Title: TRPV3-ANO1 interaction positively regulates wound healing in keratinocytes.
Volume: 6
Issue: 1
Pages: 88
•
•
•
•
•
Publication
21146788 | J:167037
First Author: Donkó A
Year: 2010
Journal: Free Radic Biol Med
Title: Urothelial cells produce hydrogen peroxide through the activation of Duox1.
Volume: 49
Issue: 12
Pages: 2040-8
•
•
•
•
•
Publication
36070688 | J:328552
First Author: Caires R
Year: 2022
Journal: Cell Rep
Title: Genetic- and diet-induced ω-3 fatty acid enrichment enhances TRPV4-mediated vasodilation in mice.
Volume: 40
Issue: 10
Pages: 111306
•
•
•
•
•
Publication
15194687 | J:92550
First Author: Hu HZ
Year: 2004
Journal: J Biol Chem
Title: 2-aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3.
Volume: 279
Issue: 34
Pages: 35741-8
•
•
•
•
•
Publication
27913425 | J:238785
First Author: Suresh K
Year: 2017
Journal: Am J Physiol Lung Cell Mol Physiol
Title: CD36 mediates H2O2-induced calcium influx in lung microvascular endothelial cells.
Volume: 312
Issue: 1
Pages: L143-L153
•
•
•
•
•
Publication
30848676 | J:272385
     
First Author: Collier DM
Year: 2019
Journal: Am J Physiol Heart Circ Physiol
Title: Extracellular histones induce calcium signals in the endothelium of resistance-sized mesenteric arteries and cause loss of endothelium-dependent dilation.
•
•
•
•
•
Publication
18268148 | J:148452
First Author: Saliez J
Year: 2008
Journal: Circulation
Title: Role of caveolar compartmentation in endothelium-derived hyperpolarizing factor-mediated relaxation: Ca2+ signals and gap junction function are regulated by caveolin in endothelial cells.
Volume: 117
Issue: 8
Pages: 1065-74
•
•
•
•
•
Publication
31150667 | J:309081
 
First Author: Sakuta H
Year: 2020
Journal: Neurosci Res
Title: Nax-positive glial cells in the organum vasculosum laminae terminalis produce epoxyeicosatrienoic acids to induce water intake in response to increases in [Na+] in body fluids.
Volume: 154
Pages: 45-51
•
•
•
•
•
Publication
26945080 | J:233007
First Author: Yap FC
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: Endothelial SK3 channel-associated Ca2+ microdomains modulate blood pressure.
Volume: 310
Issue: 9
Pages: H1151-63
•
•
•
•
•
Publication
25564678 | J:259447
First Author: Sullivan MN
Year: 2015
Journal: Sci Signal
Title: Localized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilation.
Volume: 8
Issue: 358
Pages: ra2
•
•
•
•
•
Publication
24495803 | J:218579
First Author: Jablonski CL
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Integrin α1β1 participates in chondrocyte transduction of osmotic stress.
Volume: 445
Issue: 1
Pages: 184-90
•
•
•
•
•
Publication
29037241 | J:321381
First Author: Yi M
Year: 2017
Journal: J Neuroinflammation
Title: The potassium channel KCa3.1 constitutes a pharmacological target for astrogliosis associated with ischemia stroke.
Volume: 14
Issue: 1
Pages: 203
•
•
•
•
•
Publication
31866822 | J:288857
 
First Author: Wang S
Year: 2019
Journal: Front Mol Neurosci
Title: Transient Receptor Potential Cation Channel Subfamily Vanilloid 4 and 3 in the Inner Ear Protect Hearing in Mice.
Volume: 12
Pages: 296
•
•
•
•
•
Publication
26019339 | J:222239
First Author: Kim KJ
Year: 2015
Journal: J Neurosci
Title: Astrocyte contributions to flow/pressure-evoked parenchymal arteriole vasoconstriction.
Volume: 35
Issue: 21
Pages: 8245-57
•
•
•
•
•
Publication
25903376 | J:243253
First Author: Majhi RK
Year: 2015
Journal: FEBS J
Title: Functional expression of TRPV channels in T cells and their implications in immune regulation.
Volume: 282
Issue: 14
Pages: 2661-81
•
•
•
•
•
Publication
25914628 | J:321368
 
First Author: Jie P
Year: 2015
Journal: Front Cell Neurosci
Title: Blockage of transient receptor potential vanilloid 4 inhibits brain edema in middle cerebral artery occlusion mice.
Volume: 9
Pages: 141
•
•
•
•
•
Publication
38568964 | J:354616
First Author: Garrud TAC
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: WNK kinase is a vasoactive chloride sensor in endothelial cells.
Volume: 121
Issue: 15
Pages: e2322135121
•
•
•
•
•
Publication
37963195 | J:354785
First Author: Mata-Daboin A
Year: 2023
Journal: Sci Signal
Title: Vasodilators activate the anion channel TMEM16A in endothelial cells to reduce blood pressure.
Volume: 16
Issue: 811
Pages: eadh9399
•
•
•
•
•
Publication
32178446 | J:298458
 
First Author: Kogiso H
Year: 2020
Journal: Int J Mol Sci
Title: Airway Ciliary Beating Affected by the Pcp4 Dose-Dependent [Ca2+]i Increase in Down Syndrome Mice, Ts1Rhr.
Volume: 21
Issue: 6
•
•
•
•
•
Publication
35432302 | J:323919
 
First Author: Yarishkin O
Year: 2022
Journal: Front Immunol
Title: Emergent Temporal Signaling in Human Trabecular Meshwork Cells: Role of TRPV4-TRPM4 Interactions.
Volume: 13
Pages: 805076
•
•
•
•
•
Publication
28111539 | J:247526
 
First Author: Ritter KE
Year: 2016
Journal: Front Neurosci
Title: Dynamic Expression of Serotonin Receptor 5-HT3A in Developing Sensory Innervation of the Lower Urinary Tract.
Volume: 10
Pages: 592
•
•
•
•
•
Publication
30118343 | J:272447
First Author: Diaz-Otero JM
Year: 2018
Journal: Am J Physiol Heart Circ Physiol
Title: Mineralocorticoid receptor antagonism improves parenchymal arteriole dilation via a TRPV4-dependent mechanism and prevents cognitive dysfunction in hypertension.
Volume: 315
Issue: 5
Pages: H1304-H1315
•
•
•
•
•
Publication
28122715 | J:309794
First Author: Siroky BJ
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: Primary cilia regulate the osmotic stress response of renal epithelial cells through TRPM3.
Volume: 312
Issue: 4
Pages: F791-F805
•
•
•
•
•
Publication
33122390 | J:297669
First Author: Turovsky EA
Year: 2020
Journal: J Neurosci
Title: Mechanosensory Signaling in Astrocytes.
Volume: 40
Issue: 49
Pages: 9364-9371
•
•
•
•
•
Publication
26840527 | J:256657
First Author: Sonkusare SK
Year: 2016
Journal: J Physiol
Title: Inward rectifier potassium (Kir2.1) channels as end-stage boosters of endothelium-dependent vasodilators.
Volume: 594
Issue: 12
Pages: 3271-85
•
•
•
•
•
Publication
30974795 | J:290976
 
First Author: Kameda T
Year: 2019
Journal: Int J Mol Sci
Title: Expression and Activity of TRPA1 and TRPV1 in the Intervertebral Disc: Association with Inflammation and Matrix Remodeling.
Volume: 20
Issue: 7
•
•
•
•
•
Publication
34320366 | J:316112
First Author: Wong NR
Year: 2021
Journal: Immunity
Title: Resident cardiac macrophages mediate adaptive myocardial remodeling.
Volume: 54
Issue: 9
Pages: 2072-2088.e7
•
•
•
•
•
Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom