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Search results 801 to 900 out of 968 for Tub

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1.406s

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Type Details Score
Allele
Tulp3<Gt(IST14647F6)Tigm> | MGI:5249031
 
Name: TUB like protein 3; gene trap IST14647F6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Tulp3<Gt(IST14648G9)Tigm> | MGI:5249123
 
Name: TUB like protein 3; gene trap IST14648G9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Tulp3<Gt(IST14663H8)Tigm> | MGI:5249564
 
Name: TUB like protein 3; gene trap IST14663H8, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Tulp2<Gt(IST14679D8)Tigm> | MGI:5251334
 
Name: TUB like protein 2; gene trap IST14679D8, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Tulp1<Gt(IST14704F2)Tigm> | MGI:5256567
 
Name: TUB like protein 1; gene trap IST14704F2, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Tulp2<Gt(IST14969B9)Tigm> | MGI:5272029
 
Name: TUB like protein 2; gene trap IST14969B9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Tulp1<Gt(IST14944G3)Tigm> | MGI:5272470
 
Name: TUB like protein 1; gene trap IST14944G3, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Tulp3<Gt(IST15069B9)Tigm> | MGI:5277498
 
Name: TUB like protein 3; gene trap IST15069B9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Tulp2<Gt(IST15013D2)Tigm> | MGI:5280735
 
Name: TUB like protein 2; gene trap IST15013D2, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Tulp2<tm1e(EUCOMM)Hmgu> | MGI:5294076
Name: TUB like protein 2; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Tulp2<tm1a(EUCOMM)Hmgu> | MGI:5294190
Name: TUB like protein 2; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Tulp1<tm1a(EUCOMM)Wtsi> | MGI:5296225
Name: TUB like protein 1; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Tulp1<tm1e(EUCOMM)Wtsi> | MGI:5296210
Name: TUB like protein 1; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Tulp4<tm1e(EUCOMM)Hmgu> | MGI:5516640
Name: TUB like protein 4; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Tulp3<tm1b(EUCOMM)Hmgu> | MGI:5548429
Name: TUB like protein 3; targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Strain
MGI:5641963 | C57BL/6J-Tub<m1Btlr>
Attribute String: mutant strain, chemically induced mutation, coisogenic
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Allele
Tulp3<tm1c(EUCOMM)Hmgu> | MGI:5752546
Name: TUB like protein 3; targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Tulp4<em1(IMPC)Mbp> | MGI:6152667
Name: TUB like protein 4; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Tulp2<em1(IMPC)Mbp> | MGI:6430648
Name: TUB like protein 2; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6724568 | C57BL/6-Tulp2<em1Huizh>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Tulp2<em1Smoc> | MGI:7293040
Name: TUB like protein 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Tulp2<tm1Osb> | MGI:7488119
Name: TUB like protein 2; targeted mutation 1, Research Institute for Microbial Diseases, Osaka University
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:7591759 | C57BL/6J-Tub<em1Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7590504 | C57BL/6J-Tulp3<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Tulp1<em1Smoc> | MGI:7626973
Name: TUB like protein 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:7783446 | C57BL/6J-Tulp2<em1Zfhu>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7837128 | C57BL/6JCya-Tulp1<em1Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7839725 | C57BL/6JCya-Tulp1<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Tulp3/Tulp3
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tulp1/Tulp1
Background: involves: 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tub/Tub
Background: C57BL/6-Tub
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tulp1/Tulp1
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tub/Tub
Background: C57BL/6J-Tub
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tulp3/Tulp3
Background: involves: C57BL/6J * FVB/NJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tulp2/Tulp2
Background: C57BL/6-Tulp2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tulp2/Tulp2
Background: C57BL/6J-Tulp2
Zygosity: hm
Has Mutant Allele: true
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Publication
11483369 | J:71488
First Author: Heikenwälder MF
Year: 2001
Journal: Gene
Title: Molecular cloning, expression and regulation of the avian tubby-like protein 1 (tulp1) gene.
Volume: 273
Issue: 1
Pages: 131-9
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Publication
19334287 | J:148411
First Author: Cameron DA
Year: 2009
Journal: Dev Dyn
Title: Tulp3 is a critical repressor of mouse hedgehog signaling.
Volume: 238
Issue: 5
Pages: 1140-9
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Publication
31825820 | J:283254
First Author: Ferent J
Year: 2019
Journal: Cell Rep
Title: The Ciliary Protein Arl13b Functions Outside of the Primary Cilium in Shh-Mediated Axon Guidance.
Volume: 29
Issue: 11
Pages: 3356-3366.e3
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Publication
- | J:357849
     
First Author: Wang W
Year: 2024
Journal: Elife
Title: Control of ciliary transcriptional programs during spermatogenesis by antagonistic transcription factors.
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Publication
30799239 | J:276614
First Author: Hwang SH
Year: 2019
Journal: Curr Biol
Title: Tulp3 Regulates Renal Cystogenesis by Trafficking of Cystoproteins to Cilia.
Volume: 29
Issue: 5
Pages: 790-802.e5
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Strain
MGI:6756407 | B6.Cg-Tulp1<tm1Pjn> Tg(Map1a)56Pjn/Pjn
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:6335875 | C57BL/6N-Tulp4<tm1a(KOMP)Wtsi>/Biat
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:6143417 | C57BL/6N-Tulp3<tm1a(EUCOMM)Hmgu>/HMmucd
Attribute String: mutant strain, coisogenic, targeted mutation
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Strain
MGI:5557080 | C57BL/6NTac-Tulp3<tm1a(EUCOMM)Hmgu>/H
Attribute String: coisogenic, targeted mutation
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Strain
MGI:5630160 | C57BL/6N-Tulp3<tm1b(EUCOMM)Hmgu>/H
Attribute String: coisogenic, targeted mutation
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Strain
MGI:6122840 | C57BL/6N-Tulp3<tm1c(EUCOMM)Hmgu>/H
Attribute String: mutant strain, coisogenic, targeted mutation
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Strain
MGI:6428039 | C57BL/6NTac-Tulp3<tm1c(EUCOMM)Hmgu>/H
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:6143614 | C57BL/6NCrl-Tulp4<em1(IMPC)Mbp>/Mmucd
Attribute String: mutant strain, coisogenic, endonuclease-mediated mutation
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Strain
MGI:6474508 | C57BL/6NCrl-Tulp2<em1(IMPC)Mbp>/Mmucd
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6696575 | C57BL/6N-Tulp2<em1(IMPC)Mbp>/MbpMmucd
Attribute String: coisogenic, targeted mutation
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Strain
MGI:7507393 | B6;D2-Tulp2<em1Osb>/OsbRbrc
Attribute String: endonuclease-mediated mutation, mutant stock
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Strain
MGI:7507391 | STOCK Tulp2<tm1Osb>/3BOsbRbrc
Attribute String: mutant stock, targeted mutation
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Strain
MGI:7507392 | C57BL/6N-Tulp2<tm1Osb>/1BOsbRbrc
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:7507390 | STOCK Tulp2<tm1Osb>/4AOsbRbrc
Attribute String: mutant stock, targeted mutation
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Strain
MGI:6476564 | C57BL/6JSmoc-Tulp1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Tulp3/Tulp3<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Shh/Shh Tulp3/Tulp3
Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeH * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tulp3/Tulp3
Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeH * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smo/Smo Tulp3/Tulp3
Background: involves: 129X1/SvJ * C3H/HeH * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gli3/Gli3 Tulp3/Tulp3
Background: involves: C3H/HeH * C3H/HeJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tulp3/Tulp3<+>
Background: involves: C3H/HeH * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tulp3/Tulp3
Background: involves: C57BL/6 * C57BL/6N * FVB/NJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Map1a)56Pjn/? Tulp1/Tulp1
Background: B6.Cg-Tulp1 Tg(Map1a)56Pjn/Pjn
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tulp4/Tulp4
Background: involves: C57BL/6N * C57BL/6NRj
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tulp2/Tulp2
Background: C57BL/6N-Tulp2/MbpMmucd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tulp3/Tulp3
Background: C57BL/6N-Tulp3/H
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tulp4/Tulp4
Background: C57BL/6NCrl-Tulp4/Mmucd
Zygosity: hm
Has Mutant Allele: true
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Publication
20889716 | J:164641
First Author: Mukhopadhyay S
Year: 2010
Journal: Genes Dev
Title: TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia.
Volume: 24
Issue: 19
Pages: 2180-93
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Publication
30799240 | J:284006
First Author: Legué E
Year: 2019
Journal: Curr Biol
Title: Tulp3 Is a Ciliary Trafficking Gene that Regulates Polycystic Kidney Disease.
Volume: 29
Issue: 5
Pages: 803-812.e5
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Publication
19223390 | J:147584
First Author: Patterson VL
Year: 2009
Journal: Hum Mol Genet
Title: Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway.
Volume: 18
Issue: 10
Pages: 1719-39
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Genotype
Genotype
Symbol: Gli3/Gli3<+> Tulp3/Tulp3
Background: involves: C3H/HeH * C3H/HeJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gli3/Gli3 Tulp3/Tulp3<+>
Background: involves: C3H/HeH * C3H/HeJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tulp4/Tulp4<+>
Background: involves: C57BL/6N * C57BL/6NRj
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tulp3/Tulp3<+>
Background: C57BL/6N-Tulp3/H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tulp4/Tulp4<+>
Background: C57BL/6NCrl-Tulp4/Mmucd
Zygosity: ht
Has Mutant Allele: true
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Publication
31761534 | J:282613
First Author: Hilgendorf KI
Year: 2019
Journal: Cell
Title: Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis.
Volume: 179
Issue: 6
Pages: 1289-1305.e21
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Publication
11595174 | J:71635
First Author: Li QZ
Year: 2001
Journal: Gene
Title: Molecular cloning and characterization of the mouse and human TUSP gene, a novel member of the tubby superfamily.
Volume: 273
Issue: 2
Pages: 275-84
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Publication
26305592 | J:239783
First Author: Garcia-Gonzalo FR
Year: 2015
Journal: Dev Cell
Title: Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling.
Volume: 34
Issue: 4
Pages: 400-409
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Publication
36971348 | J:356260
 
First Author: Elliott KH
Year: 2023
Journal: Development
Title: Identification of a heterogeneous and dynamic ciliome during embryonic development and cell differentiation.
Volume: 150
Issue: 8
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Publication
19286674 | J:147574
First Author: Norman RX
Year: 2009
Journal: Hum Mol Genet
Title: Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling.
Volume: 18
Issue: 10
Pages: 1740-54
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Publication
11471064 | J:70759
First Author: Planchart A
Year: 2001
Journal: Mamm Genome
Title: Experimental and computational approaches yield a high-resolution, 1-Mb physical map of the region harboring the mouse t haplotype sterility factor, tcs1.
Volume: 12
Issue: 8
Pages: 668-70
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Genotype
Genotype
Symbol: Gli3/Gli3<+> Tulp3/Tulp3<+>
Background: involves: C3H/HeH * C3H/HeJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tulp3/Tulp3
Background: involves: C57BL/6 * C57BL/6J * C57BL/6N * FVB/NJ
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tulp3/Tulp3 Tg(Pax8-rtTA2S*M2)1Koes/? Tg(tetO-cre)1Jaw/?
Background: involves: 129 * C57BL/6 * C57BL/6N * DBA * SJL
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
E-GEOD-29752 | RNA-Seq of mouse eye and retina tissues from wild type and Nrl transcription factor knockout mice
Series Id: GSE29752
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Protein
Q3UEX1
Organism: Mus musculus/domesticus
Length: 167  
Fragment?: true
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Protein
A0A1B0GSC0
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: true
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Protein
Q3UQE5
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: false
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Protein
A0A0N4SVN5
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: true
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Protein
Q8CBS7
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: false
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Publication
11801719 | -
First Author: Ikeda A
Year: 2002
Journal: J Cell Sci
Title: The tubby-like proteins, a family with roles in neuronal development and function.
Volume: 115
Issue: Pt 1
Pages: 9-14
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Protein Domain
IPR005398 | Tubby_N
Type: Domain
Description: A mutation in the mouse tub gene causes maturity-onset obesity, insulin resistance and sensory deficits [, ]. By contrast with the rapid juvenile-onset weight gain seen in diabetes (db) and obese (ob) mice, obesity in tubby mice develops gradually, and strongly resembles the late-onset obesity observed in the human population []. Excessive deposition of adipose tissue culminates in a two-fold increase of body weight. Tubby mice also suffer retinal degeneration and neurosensory hearing loss. The tripartite character of the tubby phenotype is highly similar to human obesity syndromes, such as Alstrom and Bardet-Biedl. Although these phenotypes indicate a vital role for tubby proteins, no biochemical function has yet been ascribed to any family member [], although it has been suggested that the phenotypic features of tubby mice may be the result of cellular apoptosis triggered by expression of the mutuated tub gene.Mammalian tub is a hydrophilic protein of ~500 residues. Tub carries a nuclear localisation signal and is able to activate transcription []. The N-terminal portion of the protein is conserved neither in length nor sequence, but the C-terminal 250 residues are highly conserved. The C-terminal extremity contains a cysteine residue that might play an important role in the normal functioning of these proteins. The C-terminal is represented by .
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Publication
27727273 | J:236236
First Author: Hong CJ
Year: 2016
Journal: PLoS Genet
Title: Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function.
Volume: 12
Issue: 10
Pages: e1006357
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Genotype
Genotype
Symbol: Tulp3/Tulp3 Pkd1/Pkd1 Tg(Pax8-rtTA2S*M2)1Koes/? Tg(tetO-cre)1Jaw/?
Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6N * DBA * SJL
Zygosity: cn
Has Mutant Allele: true
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Protein
Q3TMT9
Organism: Mus musculus/domesticus
Length: 301  
Fragment?: true
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Protein
O88413
Organism: Mus musculus/domesticus
Length: 460  
Fragment?: false
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Protein
P46686
Organism: Mus musculus/domesticus
Length: 562  
Fragment?: false
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Protein
P50586
Organism: Mus musculus/domesticus
Length: 505  
Fragment?: false
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Protein
A0A0R4J1P1
Organism: Mus musculus/domesticus
Length: 459  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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