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Search results 801 to 865 out of 865 for Vangl2

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Type Details Score
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
23988578 | J:202339
First Author: Sittaramane V
Year: 2013
Journal: Dev Biol
Title: The PCP protein Vangl2 regulates migration of hindbrain motor neurons by acting in floor plate cells, and independently of cilia function.
Volume: 382
Issue: 2
Pages: 400-12
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Publication
20558380 | -
First Author: Lei YP
Year: 2010
Journal: N Engl J Med
Title: VANGL2 mutations in human cranial neural-tube defects.
Volume: 362
Issue: 23
Pages: 2232-5
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Interaction Experiment
Montcouquiol M (2006)
Description: Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals.
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Interaction Experiment
Hu Z (2023)
Description: VANGL2 inhibits antiviral IFN-I signaling by targeting TBK1 for autophagic degradation.
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Allele
Gt(ROSA)26Sor<tm1(Vangl2)Yy> | MGI:6833866
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Yingzi Yang
Allele Type: Targeted
Attribute String: Conditional ready, Epitope tag, Inserted expressed sequence
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Interaction Experiment
Torban E (2004)
Description: Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family.
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Allele
Igs1<tm4(CAG-Bgeo,-Vangl2)Nat> | MGI:5314813
Name: intergenic site 1; targeted mutation 4, Jeremy Nathans
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, No functional change, Reporter
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Strain
MGI:5658217 | B6;129-Igs1<tm4(CAG-Bgeo,-Vangl2)Nat>/J
Attribute String: mutant stock, targeted mutation
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Allele
Gt(ROSA)26Sor<tm2(Vangl2*)Yy> | MGI:6833868
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Yingzi Yang
Allele Type: Targeted
Attribute String: Conditional ready, Epitope tag, Inserted expressed sequence
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Allele
Gt(ROSA)26Sor<tm3(Vangl2*)Yy> | MGI:6833876
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Yingzi Yang
Allele Type: Targeted
Attribute String: Conditional ready, Epitope tag, Inserted expressed sequence
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Genotype
Genotype
Symbol: Igs1/Igs1
Background: involves: 129 * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Protein
Q80Z96
Organism: Mus musculus/domesticus
Length: 526  
Fragment?: false
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Protein
Q91ZD4
Organism: Mus musculus/domesticus
Length: 521  
Fragment?: false
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Protein
F7BWJ0
Organism: Mus musculus/domesticus
Length: 253  
Fragment?: true
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Protein
Q6ZPV8
Organism: Mus musculus/domesticus
Length: 575  
Fragment?: true
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Protein
D3Z374
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: true
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Protein
A0A0H2UH25
Organism: Mus musculus/domesticus
Length: 393  
Fragment?: false
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Protein
D3Z4X2
Organism: Mus musculus/domesticus
Length: 130  
Fragment?: true
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Protein
E0CX72
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: true
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Protein
D3YY75
Organism: Mus musculus/domesticus
Length: 561  
Fragment?: false
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Protein
Q3UXU7
Organism: Mus musculus/domesticus
Length: 476  
Fragment?: false
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Publication
24981109 | -
First Author: Hatakeyama J
Year: 2014
Journal: Endocr Relat Cancer
Title: Vangl1 and Vangl2: planar cell polarity components with a developing role in cancer.
Volume: 21
Issue: 5
Pages: R345-56
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Protein Domain
IPR009539 | VANGL
Type: Family
Description: VANGL proteins play important roles in the establishment of planar cell polarity (PCP) []. Vangl2 is required for retinal axon guidance [], kidney-branching morphogenesis and glomerular maturation []. It also plays a role in the orientation of stereociliary bundles in the cochlea and is required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process []. It is required for cell surface localization of FZD3 and FZD6 in the inner ear [].
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HT Experiment
E-GEOD-24276 | Fz1Fz2 double knock out mouse palate microarray (E13.5)
Series Id: GSE24276
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE140779 | A mammalian Wnt5a-Ror2-angl2 axis controls the cytoskeleton and confers cellular properties required for alveologenesis
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
34613779 | J:346427
First Author: Ban Y
Year: 2021
Journal: Sci Adv
Title: Prickle promotes the formation and maintenance of glutamatergic synapses by stabilizing the intercellular planar cell polarity complex.
Volume: 7
Issue: 41
Pages: eabh2974
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Publication
37828896 | J:342410
 
First Author: Cheong SS
Year: 2023
Journal: Dis Model Mech
Title: A method for TAT-Cre recombinase-mediated floxed allele modification in ex vivo tissue slices.
Volume: 16
Issue: 11
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Publication
20962251 | J:170159
First Author: Hayashi K
Year: 2011
Journal: Biol Reprod
Title: WNTs in the neonatal mouse uterus: potential regulation of endometrial gland development.
Volume: 84
Issue: 2
Pages: 308-19
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Publication
24927917 | J:310320
First Author: Yang T
Year: 2014
Journal: Cell Tissue Res
Title: Prickle1 is necessary for the caudal migration of murine facial branchiomotor neurons.
Volume: 357
Issue: 3
Pages: 549-61
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Publication
27055101 | J:301941
First Author: Treat AC
Year: 2016
Journal: PLoS One
Title: The PDZ Protein Na+/H+ Exchanger Regulatory Factor-1 (NHERF1) Regulates Planar Cell Polarity and Motile Cilia Organization.
Volume: 11
Issue: 4
Pages: e0153144
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Publication
30414501 | J:270306
First Author: Richards T
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Atmin modulates Pkhd1 expression and may mediate Autosomal Recessive Polycystic Kidney Disease (ARPKD) through altered non-canonical Wnt/Planar Cell Polarity (PCP) signalling.
Volume: 1865
Issue: 2
Pages: 378-390
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Publication
21840926 | J:177787
First Author: Seo JH
Year: 2011
Journal: Hum Mol Genet
Title: Mutations in the planar cell polarity gene, Fuzzy, are associated with neural tube defects in humans.
Volume: 20
Issue: 22
Pages: 4324-33
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Publication
28935705 | J:245765
First Author: Goodyear RJ
Year: 2017
Journal: Development
Title: A tectorin-based matrix and planar cell polarity genes are required for normal collagen-fibril orientation in the developing tectorial membrane.
Volume: 144
Issue: 21
Pages: 3978-3989
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Publication
28923978 | J:252661
First Author: Moreno-Fortuny A
Year: 2017
Journal: Biol Open
Title: MCAM contributes to the establishment of cell autonomous polarity in myogenic and chondrogenic differentiation.
Volume: 6
Issue: 11
Pages: 1592-1601
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Publication
39092607 | J:353338
 
First Author: Satta JP
Year: 2024
Journal: Development
Title: Exploring the principles of embryonic mammary gland branching morphogenesis.
Volume: 151
Issue: 15
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Publication
37589570 | J:340498
 
First Author: Fernández-Santos B
Year: 2023
Journal: Dis Model Mech
Title: The loop-tail mouse model displays open and closed caudal neural tube defects.
Volume: 16
Issue: 8
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Publication
39791757 | J:361141
 
First Author: Ahmad S
Year: 2025
Journal: Cells
Title: Small Extracellular Vesicles Promote Axon Outgrowth by Engaging the Wnt-Planar Cell Polarity Pathway.
Volume: 14
Issue: 1
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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